ZA857358B - Carboxylalkyldipeptides,their preparation and pharmaceutical compositions containing them - Google Patents

Carboxylalkyldipeptides,their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA857358B
ZA857358B ZA857358A ZA857358A ZA857358B ZA 857358 B ZA857358 B ZA 857358B ZA 857358 A ZA857358 A ZA 857358A ZA 857358 A ZA857358 A ZA 857358A ZA 857358 B ZA857358 B ZA 857358B
Authority
ZA
South Africa
Prior art keywords
carboxylalkyldipeptides
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
ZA857358A
Other languages
English (en)
Inventor
David Roy Andrews
Federico Carlos Arejola Gaeta
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA857358B publication Critical patent/ZA857358B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA857358A 1984-09-24 1985-09-24 Carboxylalkyldipeptides,their preparation and pharmaceutical compositions containing them ZA857358B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/653,186 US4556655A (en) 1984-09-24 1984-09-24 Antihypertensive compounds having both diuretic and angiotensin converting enzyme inhibitory activity

Publications (1)

Publication Number Publication Date
ZA857358B true ZA857358B (en) 1986-05-28

Family

ID=24619842

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA857358A ZA857358B (en) 1984-09-24 1985-09-24 Carboxylalkyldipeptides,their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
US (1) US4556655A (xx)
EP (1) EP0195817B1 (xx)
JP (1) JPS62500241A (xx)
AU (1) AU581388B2 (xx)
CA (1) CA1278150C (xx)
DE (1) DE3573784D1 (xx)
DK (1) DK241686D0 (xx)
IL (1) IL76484A (xx)
NZ (1) NZ213581A (xx)
PH (1) PH22607A (xx)
WO (1) WO1986001803A1 (xx)
ZA (1) ZA857358B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766110A (en) * 1981-08-21 1988-08-23 Ryan James W Novel complex amido and imido derivatives of carboxyalkyl peptides
AU581929B2 (en) * 1985-09-16 1989-03-09 Schering Corporation Antihypertensive agents, pharmaceutical compositions containing them and processes for the preparation of the agents and compositions
US4634689A (en) * 1985-10-31 1987-01-06 Schering Corporation Phosphinylalkanoyl imino acids
IL120310A (en) * 1996-03-01 2002-02-10 Akzo Nobel Nv Serine protease inhibitors and pharmaceuticals containing them
JPWO2004065368A1 (ja) * 2003-01-21 2006-05-18 大原薬品工業株式会社 トランドラプリル合成中間体の製造方法
JP2008545006A (ja) 2005-07-05 2008-12-11 シプラ・リミテッド Ace阻害剤の合成方法
EP1864973A1 (en) * 2006-06-09 2007-12-12 Sochinaz SA Process for the preparation of perindopril and salts thereof
WO2011009021A1 (en) 2009-07-16 2011-01-20 Abbott Laboratories Processes for the synthesis of (2s, 3ar, 7as)-octahydro-1h-indole carboxylic acid as an intermediate for trandolapril

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431644A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
DE3360065D1 (en) * 1982-03-08 1985-03-28 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4468396A (en) * 1982-12-20 1984-08-28 Schering Corporation Antihypertensive benzothiadiazines

Also Published As

Publication number Publication date
AU581388B2 (en) 1989-02-16
EP0195817B1 (en) 1989-10-18
AU4963985A (en) 1986-04-08
NZ213581A (en) 1989-04-26
IL76484A (en) 1990-02-09
DK241686A (da) 1986-05-23
DK241686D0 (da) 1986-05-23
CA1278150C (en) 1990-12-18
DE3573784D1 (en) 1989-11-23
WO1986001803A1 (en) 1986-03-27
JPS62500241A (ja) 1987-01-29
PH22607A (en) 1988-10-17
EP0195817A1 (en) 1986-10-01
US4556655A (en) 1985-12-03
IL76484A0 (en) 1986-01-31

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