ZA856807B - A tumor therapeutic agent and a process for its preparation - Google Patents
A tumor therapeutic agent and a process for its preparationInfo
- Publication number
- ZA856807B ZA856807B ZA856807A ZA856807A ZA856807B ZA 856807 B ZA856807 B ZA 856807B ZA 856807 A ZA856807 A ZA 856807A ZA 856807 A ZA856807 A ZA 856807A ZA 856807 B ZA856807 B ZA 856807B
- Authority
- ZA
- South Africa
- Prior art keywords
- therapeutic agent
- preparation
- tumor therapeutic
- monoclonal antibodies
- antigens
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 102000005348 Neuraminidase Human genes 0.000 abstract 1
- 108010006232 Neuraminidase Proteins 0.000 abstract 1
- 210000005260 human cell Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Window Of Vehicle (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Saccharide Compounds (AREA)
Abstract
The process entails either tumour cells which carry antigens which are bound by the monoclonal antibodies described in German Offenlegungsschrift 33 29 184 being dried or stabilised by a chemical treatment, or antigens being isolated from human cells using these monoclonal antibodies, and converted into a therapeutic agent, adding neuraminidase where appropriate.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843432714 DE3432714A1 (en) | 1984-09-06 | 1984-09-06 | TUMOR THERAPEUTICS AND METHOD FOR THE PRODUCTION THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA856807B true ZA856807B (en) | 1986-04-30 |
Family
ID=6244749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA856807A ZA856807B (en) | 1984-09-06 | 1985-09-05 | A tumor therapeutic agent and a process for its preparation |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0173951B1 (en) |
JP (1) | JPS6168427A (en) |
AT (1) | ATE64531T1 (en) |
CA (1) | CA1277600C (en) |
DE (2) | DE3432714A1 (en) |
DK (1) | DK172253B1 (en) |
ES (1) | ES8704082A1 (en) |
FI (1) | FI88360C (en) |
GR (1) | GR852149B (en) |
IE (1) | IE58638B1 (en) |
IL (1) | IL76289A (en) |
PT (1) | PT81093B (en) |
ZA (1) | ZA856807B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3806565A1 (en) * | 1988-03-01 | 1989-09-14 | Deutsches Krebsforsch | VIRUS-MODIFIED TUMOR VACCINES FOR THE IMMUNOTHERAPY OF TUMOR METAL KEYS |
AT398900B (en) * | 1991-02-12 | 1995-02-27 | Pekar Rudolf Dr | Vaccine for immunotherapy |
US7105159B1 (en) | 1992-11-05 | 2006-09-12 | Sloan-Kettering Institute For Cancer Research | Antibodies to prostate-specific membrane antigen |
US7070782B1 (en) | 1992-11-05 | 2006-07-04 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
US6953668B1 (en) | 1992-11-05 | 2005-10-11 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
DE69334071T2 (en) * | 1992-11-05 | 2007-10-25 | Sloan-Kettering Institute For Cancer Research | PROSTATE-SPECIFIC MEMBRANEANT |
US6569432B1 (en) | 1995-02-24 | 2003-05-27 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
US7037647B1 (en) | 1995-02-24 | 2006-05-02 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
DE19506483A1 (en) * | 1995-02-24 | 1996-08-29 | Jens Dr Dr Atzpodien | Antitumour vaccines |
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
EP3184539A3 (en) | 2001-10-23 | 2017-09-13 | PSMA Development Company L.L.C. | Psma antibodies |
CN1315536C (en) * | 2002-09-13 | 2007-05-16 | 李进 | Novel vaccine of tumor antigen, its preparation method and vaccine composition |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4152410A (en) * | 1975-09-03 | 1979-05-01 | Eisai Co., Ltd. | Diagnosis reagent for neoplasm and method for diagnosis of neoplasm |
DE2643215A1 (en) * | 1976-09-25 | 1978-04-06 | Bayer Ag | CANCEROSTATICALLY EFFECTIVE PREPARATIONS FROM TUMOR CELLS AND A METHOD FOR THEIR PRODUCTION |
ZA776822B (en) * | 1976-11-24 | 1979-06-27 | D Mccollester | Vaccine and method for immunotherapy of neoplastic disease |
DE2918927A1 (en) * | 1979-05-10 | 1980-11-20 | Hans Prof Dr Limburg | MEDICINAL PRODUCT FOR TREATING CARCINOMAS AND METHOD FOR THE PRODUCTION THEREOF |
US4446122A (en) * | 1979-12-28 | 1984-05-01 | Research Corporation | Purified human prostate antigen |
US4468457A (en) * | 1981-06-01 | 1984-08-28 | David M. Goldenberg | Method for producing a CSAp tryptic peptide and anti-CSAp antibodies |
DE3329184A1 (en) * | 1983-08-12 | 1985-02-21 | Behringwerke Ag, 3550 Marburg | MONOCLONAL ANTIBODIES WITH SPECIFICITY FOR MEMBRANE-ASSOCIATED ANTIGENS |
DE3416774A1 (en) * | 1984-05-07 | 1985-11-14 | Behringwerke Ag, 3550 Marburg | MONOCLONAL ANTIBODIES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE |
-
1984
- 1984-09-06 DE DE19843432714 patent/DE3432714A1/en not_active Withdrawn
-
1985
- 1985-08-27 EP EP85110757A patent/EP0173951B1/en not_active Expired - Lifetime
- 1985-08-27 DE DE8585110757T patent/DE3583265D1/en not_active Expired - Fee Related
- 1985-08-27 AT AT85110757T patent/ATE64531T1/en not_active IP Right Cessation
- 1985-09-03 DK DK402485A patent/DK172253B1/en not_active IP Right Cessation
- 1985-09-04 FI FI853389A patent/FI88360C/en not_active IP Right Cessation
- 1985-09-04 ES ES546701A patent/ES8704082A1/en not_active Expired
- 1985-09-04 GR GR852149A patent/GR852149B/el unknown
- 1985-09-04 IL IL76289A patent/IL76289A/en not_active IP Right Cessation
- 1985-09-05 JP JP60195000A patent/JPS6168427A/en active Pending
- 1985-09-05 CA CA000490026A patent/CA1277600C/en not_active Expired - Lifetime
- 1985-09-05 PT PT81093A patent/PT81093B/en not_active IP Right Cessation
- 1985-09-05 IE IE219185A patent/IE58638B1/en not_active IP Right Cessation
- 1985-09-05 ZA ZA856807A patent/ZA856807B/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI853389A0 (en) | 1985-09-04 |
ES546701A0 (en) | 1987-03-16 |
FI853389L (en) | 1986-03-07 |
DK402485D0 (en) | 1985-09-03 |
GR852149B (en) | 1986-01-03 |
DK172253B1 (en) | 1998-02-09 |
IL76289A0 (en) | 1986-01-31 |
PT81093B (en) | 1988-07-01 |
DE3583265D1 (en) | 1991-07-25 |
ATE64531T1 (en) | 1991-07-15 |
JPS6168427A (en) | 1986-04-08 |
DE3432714A1 (en) | 1986-04-24 |
PT81093A (en) | 1985-10-01 |
EP0173951B1 (en) | 1991-06-19 |
ES8704082A1 (en) | 1987-03-16 |
DK402485A (en) | 1986-03-07 |
EP0173951A3 (en) | 1988-06-08 |
FI88360B (en) | 1993-01-29 |
CA1277600C (en) | 1990-12-11 |
IE852191L (en) | 1986-03-06 |
EP0173951A2 (en) | 1986-03-12 |
IE58638B1 (en) | 1993-10-20 |
IL76289A (en) | 1992-01-15 |
FI88360C (en) | 1993-05-10 |
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