ZA855581B - 2-benzyl-4-(4-pyridyl)thiozoles and derivatives therof as immunoregulants - Google Patents
2-benzyl-4-(4-pyridyl)thiozoles and derivatives therof as immunoregulantsInfo
- Publication number
- ZA855581B ZA855581B ZA855581A ZA855581A ZA855581B ZA 855581 B ZA855581 B ZA 855581B ZA 855581 A ZA855581 A ZA 855581A ZA 855581 A ZA855581 A ZA 855581A ZA 855581 B ZA855581 B ZA 855581B
- Authority
- ZA
- South Africa
- Prior art keywords
- immunoregulants
- thiozoles
- pyridyl
- benzyl
- derivatives therof
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/634,094 US4697012A (en) | 1984-07-25 | 1984-07-25 | Morpholino pyridyl thiazole compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA855581B true ZA855581B (en) | 1986-03-26 |
Family
ID=24542414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA855581A ZA855581B (en) | 1984-07-25 | 1985-07-24 | 2-benzyl-4-(4-pyridyl)thiozoles and derivatives therof as immunoregulants |
Country Status (12)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0149884B1 (en) * | 1983-09-09 | 1992-12-16 | Takeda Chemical Industries, Ltd. | 5-pyridyl-1,3-thiazole derivatives, their production and use |
| GB9201692D0 (en) * | 1992-01-27 | 1992-03-11 | Smithkline Beecham Intercredit | Compounds |
| HUP9801057A3 (en) * | 1995-05-26 | 2000-06-28 | Bayer Ag | Pyridyl-thiazoles and their use to protect plants against infections by micro-organisms |
| JP4662764B2 (ja) | 2002-06-14 | 2011-03-30 | メルク セローノ ソシエテ アノニム | アゾールメチリデンシアニド誘導体およびそれらのタンパク質キナーゼモジュレーターとしての使用 |
| SA04250288B1 (ar) * | 2003-09-19 | 2008-07-19 | سولفاي فارماسوتيكالز بي . في | مشتقات ثيازول thiazole كمعدلات لمستقبل المكونات الكيميائية للقنب cannabinoid |
| US7294640B2 (en) | 2004-02-06 | 2007-11-13 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
| EP2616441B1 (en) * | 2010-09-17 | 2019-08-07 | Purdue Pharma L.P. | Pyridine compounds and the uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1112128A (en) * | 1965-12-22 | 1968-05-01 | Bellon Labor Sa Roger | New thiazolyl-diphenylmethane derivatives |
| IL28803A (en) * | 1966-11-18 | 1974-05-16 | Wyeth John & Brother Ltd | Oxazole and thiazole compounds,their preparation and pharmaceutical compositions containing them |
| CA962269A (en) * | 1971-05-05 | 1975-02-04 | Robert E. Grahame (Jr.) | Thiazoles, and their use as insecticides |
| US4153703A (en) * | 1977-06-30 | 1979-05-08 | Uniroyal, Inc. | Method of controlling insects and acarids with certain aryl-substituted thiazoles |
| EP0149884B1 (en) * | 1983-09-09 | 1992-12-16 | Takeda Chemical Industries, Ltd. | 5-pyridyl-1,3-thiazole derivatives, their production and use |
-
1984
- 1984-07-25 US US06/634,094 patent/US4697012A/en not_active Expired - Fee Related
-
1985
- 1985-07-16 IL IL75823A patent/IL75823A0/xx unknown
- 1985-07-18 EP EP85108969A patent/EP0169502B1/en not_active Expired - Lifetime
- 1985-07-18 DE DE8585108969T patent/DE3580317D1/de not_active Expired - Fee Related
- 1985-07-18 PT PT80833A patent/PT80833B/pt unknown
- 1985-07-22 ES ES545439A patent/ES8700255A1/es not_active Expired
- 1985-07-22 GR GR851809A patent/GR851809B/el unknown
- 1985-07-24 KR KR1019850005279A patent/KR860001105A/ko not_active Application Discontinuation
- 1985-07-24 DK DK336685A patent/DK336685A/da not_active Application Discontinuation
- 1985-07-24 AU AU45320/85A patent/AU575666B2/en not_active Expired - Fee Related
- 1985-07-24 ZA ZA855581A patent/ZA855581B/xx unknown
- 1985-07-25 JP JP16308885A patent/JPS6137784A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0169502B1 (en) | 1990-10-31 |
| DE3580317D1 (en) | 1990-12-13 |
| DK336685A (da) | 1986-01-26 |
| IL75823A0 (en) | 1985-11-29 |
| EP0169502A3 (en) | 1987-02-25 |
| ES545439A0 (es) | 1986-10-01 |
| US4697012A (en) | 1987-09-29 |
| JPS6137784A (ja) | 1986-02-22 |
| AU575666B2 (en) | 1988-08-04 |
| PT80833B (en) | 1987-05-27 |
| DK336685D0 (da) | 1985-07-24 |
| AU4532085A (en) | 1986-01-30 |
| KR860001105A (ko) | 1986-02-22 |
| ES8700255A1 (es) | 1986-10-01 |
| EP0169502A2 (en) | 1986-01-29 |
| GR851809B (US20100223739A1-20100909-C00005.png) | 1985-11-26 |
| PT80833A (en) | 1985-08-01 |
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