ZA854946B - Pyrrolo(1,2-b)(1,2,5)triazepines,a process and intermediates for their preparation and their use as medicaments - Google Patents

Pyrrolo(1,2-b)(1,2,5)triazepines,a process and intermediates for their preparation and their use as medicaments

Info

Publication number
ZA854946B
ZA854946B ZA854946A ZA854946A ZA854946B ZA 854946 B ZA854946 B ZA 854946B ZA 854946 A ZA854946 A ZA 854946A ZA 854946 A ZA854946 A ZA 854946A ZA 854946 B ZA854946 B ZA 854946B
Authority
ZA
South Africa
Prior art keywords
hydrogen
compounds
triazepines
pyrrolo
medicaments
Prior art date
Application number
ZA854946A
Other languages
English (en)
Inventor
Richard C Effland
Joseph T Klein
R Richard L Hamer
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA854946B publication Critical patent/ZA854946B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/50—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA854946A 1984-07-02 1985-07-01 Pyrrolo(1,2-b)(1,2,5)triazepines,a process and intermediates for their preparation and their use as medicaments ZA854946B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/627,329 US4517195A (en) 1984-07-02 1984-07-02 Pyrrolo[1,2-b][1,2,5]triazepines and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
ZA854946B true ZA854946B (en) 1986-02-26

Family

ID=24514226

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA854946A ZA854946B (en) 1984-07-02 1985-07-01 Pyrrolo(1,2-b)(1,2,5)triazepines,a process and intermediates for their preparation and their use as medicaments

Country Status (13)

Country Link
US (1) US4517195A (fr)
EP (1) EP0167922B1 (fr)
JP (1) JPS6118781A (fr)
KR (1) KR860001113A (fr)
AT (1) ATE51401T1 (fr)
AU (2) AU593771B2 (fr)
CA (1) CA1251790A (fr)
DE (1) DE3576822D1 (fr)
DK (1) DK298085A (fr)
ES (5) ES8702913A1 (fr)
GR (1) GR851599B (fr)
PT (1) PT80746B (fr)
ZA (1) ZA854946B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800203A (en) * 1987-09-24 1989-01-24 Hoechst-Roussel Pharmaceuticals, Inc. Pyrrolo(1,2-b)cinnolines
US5274116A (en) * 1992-07-30 1993-12-28 Hoechst-Roussel Pharmaceuticals Inc. 1-aminoacetamidopyrroles and 1-aminoacetamido-2-(substituted)pyrroles and related compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121081A (en) * 1961-08-18 1964-02-11 Du Pont 6-amino-7, 8-dicyanopyrrolo [b]-as-triazines and 7-amino-8, 9-dicyanopyrrolo [b]-[1.2.4]triazepines and their preparation
US3116203A (en) * 1962-03-14 1963-12-31 Hoffmann La Roche Oleaginous systems
GB1433103A (en) * 1974-03-20 1976-04-22 Lepetit Spa Pharmacologically active pyrrolodiazepines
US4201712A (en) * 1975-07-16 1980-05-06 Boehringer Ingelheim Gmbh Process for preparation of 6-aryl-4H-s-triazolo-[3,4-c]-thieno-[2,3-e]-1,4-diazepines
FI803908L (fi) * 1979-12-21 1981-06-22 Sandoz Ag Nya pyrrolobenszotriazepiner deras framstaellning och dessa innehaollande farmaceutiska foereningar
GR76455B (fr) * 1981-06-04 1984-08-10 Lepetit Spa

Also Published As

Publication number Publication date
ES552022A0 (es) 1987-02-16
ES557083A0 (es) 1987-08-01
CA1262904C (fr) 1989-11-14
KR860001113A (ko) 1986-02-22
EP0167922A2 (fr) 1986-01-15
ES8707536A1 (es) 1987-08-01
ES8703837A1 (es) 1987-03-01
EP0167922A3 (en) 1987-01-21
AU4722889A (en) 1990-05-17
JPS6118781A (ja) 1986-01-27
ES8703422A1 (es) 1987-02-16
GR851599B (fr) 1985-11-25
PT80746A (en) 1985-08-01
ATE51401T1 (de) 1990-04-15
AU593771B2 (en) 1990-02-22
ES8702913A1 (es) 1987-01-16
PT80746B (en) 1987-02-13
ES552024A0 (es) 1987-03-01
ES8703836A1 (es) 1987-03-01
ES552023A0 (es) 1987-03-01
DK298085A (da) 1986-01-03
DK298085D0 (da) 1985-07-01
ES544746A0 (es) 1987-01-16
US4517195A (en) 1985-05-14
AU4451485A (en) 1986-01-09
DE3576822D1 (de) 1990-05-03
CA1251790A (fr) 1989-03-28
EP0167922B1 (fr) 1990-03-28

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