ZA851611B - New sulfonic resins having a therapeutical acitivity,preparation thereof and pharmaceutical compositions containing them - Google Patents
New sulfonic resins having a therapeutical acitivity,preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- ZA851611B ZA851611B ZA851611A ZA851611A ZA851611B ZA 851611 B ZA851611 B ZA 851611B ZA 851611 A ZA851611 A ZA 851611A ZA 851611 A ZA851611 A ZA 851611A ZA 851611 B ZA851611 B ZA 851611B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- acitivity
- therapeutical
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229920005989 resin Polymers 0.000 title 1
- 239000011347 resin Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010052895 Coronary artery insufficiency Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 208000037849 arterial hypertension Diseases 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19960/84A IT1175814B (it) | 1984-03-09 | 1984-03-09 | Resine solfoniche ad attivita' terapeutica,loro preparazione e composizioni farmaceutiche che le contengono |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA851611B true ZA851611B (en) | 1985-11-27 |
Family
ID=11162658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA851611A ZA851611B (en) | 1984-03-09 | 1985-03-04 | New sulfonic resins having a therapeutical acitivity,preparation thereof and pharmaceutical compositions containing them |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4587242A (ja) |
| EP (1) | EP0154895B1 (ja) |
| JP (1) | JPH0623104B2 (ja) |
| AT (1) | ATE75614T1 (ja) |
| DE (1) | DE3585963D1 (ja) |
| ES (1) | ES8700932A1 (ja) |
| IT (1) | IT1175814B (ja) |
| ZA (1) | ZA851611B (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364620A (en) * | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| DE3719764A1 (de) * | 1987-06-13 | 1988-12-22 | Bayer Ag | Ionenaustauscherharze beladen mit chinoloncarbonsaeurederivaten, ihre herstellung und verwendung |
| FR2623714B1 (fr) * | 1987-11-26 | 1990-04-20 | Ethypharm Sa | Forme a liberation prolongee du diltiazem, et son medicament ainsi obtenu |
| US5008433A (en) * | 1988-05-18 | 1991-04-16 | Marion Laboratories, Inc. | 2-hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem |
| DE69411387T2 (de) * | 1994-09-16 | 1999-02-25 | Orion Corp. FERMION, Espoo | Verfahren zur Herstellung von pharmazeutisch aktiven Benzothiazepinderivaten. |
| US20050142097A1 (en) * | 2003-12-29 | 2005-06-30 | Deepak Thassu | Multiple active drug resin conjugate |
| JP2008546835A (ja) * | 2005-06-28 | 2008-12-25 | ユ セ ベ ソシエテ アノニム | 複数の活性薬物−樹脂抱合体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB857194A (en) * | 1957-07-05 | 1960-12-29 | Clinical Products Ltd | Therapeutic agents comprising ion-exchange resins |
| US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| BR6915295D0 (pt) * | 1969-01-25 | 1973-04-12 | Tanabe Seiyaku Co | Indicador cronologico de evento em transmissao televisada |
| US4364928A (en) * | 1979-10-23 | 1982-12-21 | Roussel-Uclaf | Novel salts of ion exchange resins of the acid type |
| US4369175A (en) * | 1981-07-27 | 1983-01-18 | Ciba-Geigy Corporation | Process for the manufacture of prolonged action vincamine preparations, the vincamine preparations so obtained, and medicaments containing them |
| JPS5910512A (ja) * | 1982-07-09 | 1984-01-20 | Tanabe Seiyaku Co Ltd | 徐放性マイクロカプセルおよびその製法 |
-
1984
- 1984-03-09 IT IT19960/84A patent/IT1175814B/it active Protection Beyond IP Right Term
-
1985
- 1985-02-28 AT AT85102208T patent/ATE75614T1/de not_active IP Right Cessation
- 1985-02-28 EP EP85102208A patent/EP0154895B1/en not_active Expired - Lifetime
- 1985-02-28 DE DE8585102208T patent/DE3585963D1/de not_active Expired - Lifetime
- 1985-03-04 ZA ZA851611A patent/ZA851611B/xx unknown
- 1985-03-07 US US06/709,081 patent/US4587242A/en not_active Expired - Lifetime
- 1985-03-08 ES ES541089A patent/ES8700932A1/es not_active Expired
- 1985-03-08 JP JP60046298A patent/JPH0623104B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES8700932A1 (es) | 1986-11-16 |
| ES541089A0 (es) | 1986-11-16 |
| EP0154895A3 (en) | 1987-05-06 |
| IT8419960A0 (it) | 1984-03-09 |
| EP0154895A2 (en) | 1985-09-18 |
| DE3585963D1 (de) | 1992-06-11 |
| ATE75614T1 (de) | 1992-05-15 |
| EP0154895B1 (en) | 1992-05-06 |
| JPH0623104B2 (ja) | 1994-03-30 |
| IT1175814B (it) | 1987-07-15 |
| JPS60208918A (ja) | 1985-10-21 |
| US4587242A (en) | 1986-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY102038A (en) | 4-substituted androstendione derivatives and process for their preparation | |
| ZA851611B (en) | New sulfonic resins having a therapeutical acitivity,preparation thereof and pharmaceutical compositions containing them | |
| ES540758A0 (es) | Un procedimiento para la preparacion de una composicion blanqueante de poroxido de hidrogeno. | |
| AR242561A1 (es) | Procedimiento para la preparacion de clorhidrato de s-(-)-1-propil-2',6'-pipecoloxilidida opticamente sustancialmente puro y procedimiento | |
| EP0166695A3 (en) | Process for the preparation of glycidyl thioethers | |
| AU610175B2 (en) | Pharmaceutical composition comprising a compound containing sulfhydryl group(s) for the treatment of otitis | |
| PH24727A (en) | Agents having renal function improving effect | |
| ES2023774A6 (es) | Procedimiento para la preparacion del intermedio de diltiazem. | |
| HUT70033A (en) | Process for producing synergetic pharmaceutical composition containing calcium channel blocking agent and calcium compound or vitamin d | |
| SE8403042D0 (sv) | Hypolipidemisk komposition | |
| GB8711407D0 (en) | Pharmaceutical composition | |
| IT8420148A0 (it) | Procedimento per la preparazione del(+)-cis-5-[2-(dimetilamino)etil]-2,3-diidro-3-idrossi-2-(p-metossifenil)-1,5-benzotiazepin-4(5h)-one acetato cloridrato | |
| JPS56156218A (en) | Inhibitor against blood platelet agglutination | |
| IT8422701A0 (it) | Procedimento per il recupero delcis(+)-3-acetilossi-5-[2-(dimetilammino)etil]-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin-4-(5h)-one cloridrato | |
| AU5783290A (en) | 2-amino-1,2,3,4-tetrahydronaphthalene derivatives with cardiovascular activity, process for their preparation and pharmaceutical compositions containing them. | |
| IT8521855A0 (it) | Procedimento per il recupero delcis(+)-3-acetilossi-5-[2-(dimetilammino)etil]-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin-4-(5h)-one cloridrato | |
| LV11324A (lv) | Panemiens 3-hidroksi-5-/2-(dimetilamino) etil/-2,3-dihidro-2-(4-metoksifenil)-1,5-benzotiazepin-4(5H)-ona iegusanai un mineta savienojuma pielietojums | |
| ES2020722A6 (es) | Procedimiento para la purificacion de intermedios para la preparacion de benzotiacepinas. | |
| NZ230745A (en) | Composition for treatment of retrovirus infection comprising tingsten oxide-containing salts | |
| HUT42767A (en) | Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one | |
| PT84299A (en) | Process for the preparation of a pharmacologically active compound of substituted oxodiazine | |
| IT8419671A0 (it) | Derivati del 3-(acetilossi)-5-[2(dimetilamino)etil]-2,3-diidro-2(4-metossifenil)-1,5-benzotiazepin-4(5h)-one, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
| IT8323108A0 (it) | Procedimento per il recupero delcis(+)-3-acetilossi-5-aperta parentesi quadrata 2-(dimetilammino)etil chiusa parentesi quadrata-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin-4-(5h)-one cloridrato. | |
| ES542610A0 (es) | Procedimiento de preparacion de una nueva composicion anti- bacteriana-antiprotozoaria sinergetica | |
| KR920011495A (ko) | 치료용 활성을 갖는 설폰산수지, 그것의 제제 및 그것을 함유한 약제 조성물 |