ZA85154B - 7-oxabicycloheptane prostaglandin analogs - Google Patents

7-oxabicycloheptane prostaglandin analogs

Info

Publication number
ZA85154B
ZA85154B ZA85154A ZA85154A ZA85154B ZA 85154 B ZA85154 B ZA 85154B ZA 85154 A ZA85154 A ZA 85154A ZA 85154 A ZA85154 A ZA 85154A ZA 85154 B ZA85154 B ZA 85154B
Authority
ZA
South Africa
Prior art keywords
prostaglandin analogs
oxabicycloheptane prostaglandin
oxabicycloheptane
analogs
prostaglandin
Prior art date
Application number
ZA85154A
Other languages
English (en)
Inventor
Masami Nakane
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ZA85154B publication Critical patent/ZA85154B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA85154A 1984-01-26 1985-01-07 7-oxabicycloheptane prostaglandin analogs ZA85154B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/573,992 US4526901A (en) 1984-01-26 1984-01-26 7-Oxabicycloheptane substituted oxamide prostaglandin analogs and their use in treating thrombolytic disease

Publications (1)

Publication Number Publication Date
ZA85154B true ZA85154B (en) 1985-08-28

Family

ID=24294243

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA85154A ZA85154B (en) 1984-01-26 1985-01-07 7-oxabicycloheptane prostaglandin analogs

Country Status (6)

Country Link
US (1) US4526901A (de)
EP (1) EP0150709A3 (de)
JP (1) JPS60178876A (de)
AU (1) AU575108B2 (de)
CA (1) CA1214177A (de)
ZA (1) ZA85154B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4533673A (en) * 1984-01-26 1985-08-06 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted enaminone prostaglandin analogs and their use in treatment of thrombolytic disease
US4588741A (en) * 1985-02-28 1986-05-13 E. R. Squibb & Sons, Inc. Platelet aggregation inhibiting and bronchoconstriction inhibiting thiabicycloheptane substituted amino prostaglandin analog derivatives, compositions, and method of use therefor
US4607048A (en) * 1985-05-16 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4654356A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
US4654355A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amide-thioamide prostaglandin analogs
US4632931A (en) * 1985-09-25 1986-12-30 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs useful in the treatment of thrombotic disease
US4652576A (en) * 1985-10-18 1987-03-24 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amide-carbamate prostaglandin analogs
US4656185A (en) * 1985-12-05 1987-04-07 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted aminoalkyl amide prostaglandin analogs
US4652578A (en) * 1986-02-24 1987-03-24 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amide prostaglandin analogs
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease
US4977174A (en) * 1989-06-12 1990-12-11 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
IE920039A1 (en) * 1991-02-01 1992-08-12 Squibb & Sons Inc Heterocyclic amido prostaglandin analogs
US5238951A (en) * 1991-02-01 1993-08-24 E. R. Squibb & Sons, Inc. Heterocyclic amido prostaglandin analogs
BR9608498B1 (pt) 1995-06-21 2008-11-18 derivados de amino bicÍclico e antagonista pgd2 contendo os mesmos.
EP1554572B1 (de) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP2671508B1 (de) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-Informatiksystem
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
GB2092589B (en) * 1979-01-05 1983-06-08 Nat Res Dev Prostaglandins
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
US4456616A (en) * 1982-12-27 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction

Also Published As

Publication number Publication date
EP0150709A2 (de) 1985-08-07
JPS60178876A (ja) 1985-09-12
CA1214177A (en) 1986-11-18
AU3754785A (en) 1985-08-01
AU575108B2 (en) 1988-07-21
US4526901A (en) 1985-07-02
EP0150709A3 (de) 1985-10-02

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