ZA827641B - Thiadiazine, oxadiazine and triazine derivatives which possess cardiotonic and/or antihypertensive activity - Google Patents
Thiadiazine, oxadiazine and triazine derivatives which possess cardiotonic and/or antihypertensive activityInfo
- Publication number
- ZA827641B ZA827641B ZA827641A ZA827641A ZA827641B ZA 827641 B ZA827641 B ZA 827641B ZA 827641 A ZA827641 A ZA 827641A ZA 827641 A ZA827641 A ZA 827641A ZA 827641 B ZA827641 B ZA 827641B
- Authority
- ZA
- South Africa
- Prior art keywords
- oxadiazine
- thiadiazine
- triazine derivatives
- antihypertensive activity
- possess cardiotonic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C07D273/02—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
- C07D273/04—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8134176 | 1981-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA827641B true ZA827641B (en) | 1983-09-28 |
Family
ID=10525837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA827641A ZA827641B (en) | 1981-11-12 | 1982-10-19 | Thiadiazine, oxadiazine and triazine derivatives which possess cardiotonic and/or antihypertensive activity |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4493835A (no) |
| EP (1) | EP0086301A1 (no) |
| JP (1) | JPS58131973A (no) |
| AU (1) | AU9000682A (no) |
| DK (1) | DK487082A (no) |
| ES (1) | ES517333A0 (no) |
| FI (1) | FI823895L (no) |
| GR (1) | GR77782B (no) |
| IL (1) | IL67098A0 (no) |
| NO (1) | NO823765L (no) |
| PT (1) | PT75828A (no) |
| ZA (1) | ZA827641B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3172252D1 (en) * | 1980-11-14 | 1985-10-17 | Ici Plc | Heterocyclic compounds |
| US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
| GB8310435D0 (en) * | 1983-04-18 | 1983-05-25 | Fujisawa Pharmaceutical Co | Triazine derivatives |
| GB8328907D0 (en) * | 1983-10-28 | 1983-11-30 | Smith Kline French Lab | Chemical compounds |
| GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| US4508718A (en) * | 1984-01-16 | 1985-04-02 | Warner-Lambert Company | Cardiotonic and antihypertensive oxadiazinone compounds |
| US4898862A (en) * | 1986-03-20 | 1990-02-06 | Sankyo Company Limited | 1,2,4-triazinone derivatives, their preparation and use |
| US5185332A (en) * | 1989-02-11 | 1993-02-09 | Orion-Yhtyma Oy | Thiadiazines and pharmaceutical compositions thereof as well as method of use |
| EP3661917B1 (en) | 2017-08-04 | 2022-05-11 | Bayer Aktiengesellschaft | 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer |
| JOP20200024A1 (ar) | 2017-08-04 | 2020-02-02 | Bayer Ag | مركبات ثنائي هيدروكساديازينون |
| EP3917915A1 (en) * | 2019-02-01 | 2021-12-08 | Bayer Aktiengesellschaft | 1,2,4-triazin-3(2h)-one compounds for the treatment of hyperproliferative diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3377345A (en) * | 1966-09-23 | 1968-04-09 | Dow Chemical Co | Substituted 3, 4, 5, 6-tetrahydro-2h-1, 3, 4-oxadiazin-2-one compounds and method ofpreparation thereof |
| FR8169M (no) * | 1967-05-17 | 1970-08-31 | ||
| US3946010A (en) * | 1975-04-09 | 1976-03-23 | E. R. Squibb & Sons, Inc. | 3-Phenyl-2,5-dihydro-as-triazin-6 (1H)-ones |
| US4097425A (en) * | 1975-08-28 | 1978-06-27 | General Electric Company | Thermoplastic formable blends, a foaming method and products made thereby |
| US4097671A (en) * | 1975-08-28 | 1978-06-27 | General Electric Company | Dihydrooxadiazinones and method for making |
| US4105848A (en) * | 1976-12-27 | 1978-08-08 | General Electric Company | Process for the production of dihydrooxadiazinone compounds |
| DE3172252D1 (en) * | 1980-11-14 | 1985-10-17 | Ici Plc | Heterocyclic compounds |
-
1982
- 1982-10-19 ZA ZA827641A patent/ZA827641B/xx unknown
- 1982-10-26 US US06/436,802 patent/US4493835A/en not_active Expired - Fee Related
- 1982-10-28 IL IL67098A patent/IL67098A0/xx unknown
- 1982-10-29 AU AU90006/82A patent/AU9000682A/en not_active Abandoned
- 1982-11-03 DK DK487082A patent/DK487082A/da not_active Application Discontinuation
- 1982-11-04 EP EP82305869A patent/EP0086301A1/en not_active Withdrawn
- 1982-11-05 GR GR69740A patent/GR77782B/el unknown
- 1982-11-10 PT PT75828A patent/PT75828A/pt unknown
- 1982-11-11 NO NO823765A patent/NO823765L/no unknown
- 1982-11-12 FI FI823895A patent/FI823895L/fi not_active Application Discontinuation
- 1982-11-12 ES ES517333A patent/ES517333A0/es active Granted
- 1982-11-12 JP JP57197841A patent/JPS58131973A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO823765L (no) | 1983-05-13 |
| IL67098A0 (en) | 1983-02-23 |
| FI823895A0 (fi) | 1982-11-12 |
| JPS58131973A (ja) | 1983-08-06 |
| US4493835A (en) | 1985-01-15 |
| AU9000682A (en) | 1983-05-19 |
| DK487082A (da) | 1983-05-13 |
| ES8404340A1 (es) | 1984-04-16 |
| GR77782B (no) | 1984-09-25 |
| PT75828A (en) | 1982-12-01 |
| FI823895L (fi) | 1983-05-13 |
| ES517333A0 (es) | 1984-04-16 |
| EP0086301A1 (en) | 1983-08-24 |
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