ZA826418B - 4a-substituted avermectin compounds - Google Patents

4a-substituted avermectin compounds

Info

Publication number
ZA826418B
ZA826418B ZA826418A ZA826418A ZA826418B ZA 826418 B ZA826418 B ZA 826418B ZA 826418 A ZA826418 A ZA 826418A ZA 826418 A ZA826418 A ZA 826418A ZA 826418 B ZA826418 B ZA 826418B
Authority
ZA
South Africa
Prior art keywords
avermectin compounds
substituted avermectin
substituted
compounds
avermectin
Prior art date
Application number
ZA826418A
Other languages
English (en)
Inventor
Helmut H Mrozik
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA826418B publication Critical patent/ZA826418B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA826418A 1981-09-03 1982-09-02 4a-substituted avermectin compounds ZA826418B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29886181A 1981-09-03 1981-09-03

Publications (1)

Publication Number Publication Date
ZA826418B true ZA826418B (en) 1984-04-25

Family

ID=23152281

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA826418A ZA826418B (en) 1981-09-03 1982-09-02 4a-substituted avermectin compounds

Country Status (6)

Country Link
EP (1) EP0074758B1 (xx)
JP (1) JPS5859988A (xx)
AU (1) AU551069B2 (xx)
DE (1) DE3272017D1 (xx)
NZ (1) NZ201681A (xx)
ZA (1) ZA826418B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920285A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−二塩基酸エステル誘導体及びその塩
US4530921A (en) * 1983-10-03 1985-07-23 Merck & Co., Inc. Avermectin epoxide derivatives and method of use
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
IT1182857B (it) * 1984-09-14 1987-10-05 Glaxo Group Ltd Composti antibiotici, composizioni antiparassitarie che li contengono e procedimento per prepararli ed applicarli
EP0180539A1 (de) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- und 13-Hydroximilbemycine
AU574852B2 (en) * 1984-10-26 1988-07-14 Sankyo Company Limited 13 - acyloxy - 5 - ketomilbemycin derivatives and preparation of 13 - hydroxy - 5 - ketomilbemycin derivatives
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
NZ216908A (en) * 1985-07-29 1989-06-28 Merck & Co Inc Avermectin derivatives
US4778809A (en) * 1985-08-23 1988-10-18 Ciba-Geigy Corporation 5-esters of milbemycins for controlling parasitic pests
GB8606123D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
JP2587241B2 (ja) * 1986-07-24 1997-03-05 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
US5212322A (en) * 1986-12-11 1993-05-18 Sankyo Company, Limited Macrolide compounds, their preparation and their use
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
EP0298423A3 (en) * 1987-07-07 1989-10-25 Kumiai Chemical Industry Co., Ltd. Antibiotic ksb-1939 compounds and production process thereof as well as pesticidal agents containing same
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
DE3888936T2 (de) * 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
JP2849389B2 (ja) * 1988-07-05 1999-01-20 三共株式会社 新規マクロライド化合物
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US5840324A (en) * 1993-05-26 1998-11-24 Commonwealth Scientific And Industrial Organisation Antiparasitic compositions
JP4509007B2 (ja) * 2005-11-08 2010-07-21 株式会社堀場製作所 エマメクチンおよびその類似化合物に対する抗体の製造方法、抗体、ハイブリドーマ、その免疫学的測定方法および測定キット
CN113735924A (zh) * 2021-09-01 2021-12-03 河北威远生物化工有限公司 一种23-酮阿维菌素B2a/B2b衍生物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992551A (en) * 1972-06-08 1976-11-16 Sankyo Company Limited Antisiotic substances B-41, their production and their use as insecticides acaricides
JPS5645890B2 (xx) * 1973-05-29 1981-10-29
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4144352A (en) * 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
JPS55131398A (en) * 1980-04-01 1980-10-13 Sankyo Co Ltd Preparation of antibiotic b-41
JPS5777686A (en) * 1980-10-31 1982-05-15 Sankyo Co Ltd Aitibiotic b-41e or b-41f, their preparations, acaricide and insecticide comprising them as active ingredients

Also Published As

Publication number Publication date
NZ201681A (en) 1985-11-08
JPH0516431B2 (xx) 1993-03-04
AU551069B2 (en) 1986-04-17
AU8790982A (en) 1983-03-10
EP0074758B1 (en) 1986-07-16
EP0074758A1 (en) 1983-03-23
DE3272017D1 (en) 1986-08-21
JPS5859988A (ja) 1983-04-09

Similar Documents

Publication Publication Date Title
GB2111488B (en) 1-oxa- and 1-thia-spirocyclic compounds
GB8417905D0 (en) Hydroxymethyl-5 oxazolidinic derivatives
ZA826418B (en) 4a-substituted avermectin compounds
IL65799A0 (en) 2-amino-1-alkanol derivatives
GB2111483B (en) 3-acylamino-4-hydroxy-phenethylamine derivatives
GB2101580B (en) Allophanoylpiperazine compounds
GB2097003B (en) Phosporus-containing compounds
GB2098604B (en) 3-substituted-2-azetidinone compounds
GB2101986B (en) Thiazolinoazetidinone derivatives
JPS57163384A (en) Benzopyranoimidazole compounds
GB2099424B (en) Isoprenylamine derivatives
GB2099419B (en) Imidazothizole derivatives
GB2155932B (en) Phenylhydrazinomethylenemalononitrile derivatives
GB2106519B (en) Aminooxazolyl compounds
GB2098613B (en) Polyisoprenylamine derivatives
GB2094297B (en) Apovincaminol derivatives
GB2104889B (en) Phenethylpiperidine compounds
DE3260986D1 (en) Anthelmintics
GB2099423B (en) Isopyrenylamine derivatives
DE3260771D1 (en) Pyridothienopyridazine compounds
GB2092587B (en) Substituted phenylcarbamoylbenzimidates
GB2112781B (en) Aminopropylaminobleomycin derivatives
GB2096998B (en) Dioxaazabicyclic compounds
ZA823153B (en) Substituted 2-aminoethanols
ZA823207B (en) Benzylazole derivatives