ZA823783B - 11 alpha-amino-androstanes - Google Patents

11 alpha-amino-androstanes

Info

Publication number
ZA823783B
ZA823783B ZA823783A ZA823783A ZA823783B ZA 823783 B ZA823783 B ZA 823783B ZA 823783 A ZA823783 A ZA 823783A ZA 823783 A ZA823783 A ZA 823783A ZA 823783 B ZA823783 B ZA 823783B
Authority
ZA
South Africa
Prior art keywords
group
alkyl
alkoxy
compounds
formula
Prior art date
Application number
ZA823783A
Other languages
English (en)
Inventor
Gordon Hanley Phillipps
David Cedric Humber
George Blanch Ewan
Barry Anthony Coomber
Anthony James Pateman
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA823783B publication Critical patent/ZA823783B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011Unsubstituted amino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA823783A 1981-05-29 1982-05-28 11 alpha-amino-androstanes ZA823783B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8116410 1981-05-29

Publications (1)

Publication Number Publication Date
ZA823783B true ZA823783B (en) 1983-03-30

Family

ID=10522121

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA823783A ZA823783B (en) 1981-05-29 1982-05-28 11 alpha-amino-androstanes

Country Status (7)

Country Link
US (1) US4497805A (xx)
EP (1) EP0066468B1 (xx)
JP (1) JPS57203100A (xx)
AT (1) ATE8641T1 (xx)
AU (1) AU8428782A (xx)
DE (1) DE3260462D1 (xx)
ZA (1) ZA823783B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1212835B (it) * 1983-08-18 1989-11-30 Lehner Ag Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
US4968675A (en) * 1988-10-28 1990-11-06 Upjohn Non-hemolytic lazaroid parenteral formulation
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1581234A (en) * 1976-04-05 1980-12-10 Glaxo Operations Ltd 11a - amino - 3a - hydroxysteroids
GB1581235A (en) * 1977-04-04 1980-12-10 Glaxo Operations Ltd 11a-amino-3a-hydroxy-steroids
AU7288081A (en) * 1980-07-16 1982-01-21 Glaxo Group Limited 11alpha-amino-androstanes
SE8104393L (sv) * 1980-07-16 1982-01-17 Glaxo Group Ltd Llalfa-amino-androstaner

Also Published As

Publication number Publication date
ATE8641T1 (de) 1984-08-15
JPS57203100A (en) 1982-12-13
US4497805A (en) 1985-02-05
DE3260462D1 (en) 1984-08-30
AU8428782A (en) 1982-12-02
EP0066468B1 (en) 1984-07-25
EP0066468A1 (en) 1982-12-08

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