JPS57203100A - 11 alpha-amino-androstanes - Google Patents

11 alpha-amino-androstanes

Info

Publication number
JPS57203100A
JPS57203100A JP57089996A JP8999682A JPS57203100A JP S57203100 A JPS57203100 A JP S57203100A JP 57089996 A JP57089996 A JP 57089996A JP 8999682 A JP8999682 A JP 8999682A JP S57203100 A JPS57203100 A JP S57203100A
Authority
JP
Japan
Prior art keywords
group
alkyl
alkoxy
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57089996A
Other languages
English (en)
Inventor
Hanrei Fuiritsupusu Goodon
Sedoritsuku Hanbaa Deibitsudo
Buranchi Yuuan Jiyooji
Antonii Kuumaa Barii
Jieimuzu Peitoman Antonii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JPS57203100A publication Critical patent/JPS57203100A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57089996A 1981-05-29 1982-05-28 11 alpha-amino-androstanes Pending JPS57203100A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8116410 1981-05-29

Publications (1)

Publication Number Publication Date
JPS57203100A true JPS57203100A (en) 1982-12-13

Family

ID=10522121

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57089996A Pending JPS57203100A (en) 1981-05-29 1982-05-28 11 alpha-amino-androstanes

Country Status (7)

Country Link
US (1) US4497805A (ja)
EP (1) EP0066468B1 (ja)
JP (1) JPS57203100A (ja)
AT (1) ATE8641T1 (ja)
AU (1) AU8428782A (ja)
DE (1) DE3260462D1 (ja)
ZA (1) ZA823783B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1212835B (it) * 1983-08-18 1989-11-30 Lehner Ag Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
US4968675A (en) * 1988-10-28 1990-11-06 Upjohn Non-hemolytic lazaroid parenteral formulation
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1581234A (en) * 1976-04-05 1980-12-10 Glaxo Operations Ltd 11a - amino - 3a - hydroxysteroids
GB1581235A (en) * 1977-04-04 1980-12-10 Glaxo Operations Ltd 11a-amino-3a-hydroxy-steroids
AU7288081A (en) * 1980-07-16 1982-01-21 Glaxo Group Limited 11alpha-amino-androstanes
SE8104393L (sv) * 1980-07-16 1982-01-17 Glaxo Group Ltd Llalfa-amino-androstaner

Also Published As

Publication number Publication date
ZA823783B (en) 1983-03-30
ATE8641T1 (de) 1984-08-15
US4497805A (en) 1985-02-05
DE3260462D1 (en) 1984-08-30
AU8428782A (en) 1982-12-02
EP0066468B1 (en) 1984-07-25
EP0066468A1 (en) 1982-12-08

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