ZA822987B - 4-(4-phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones - Google Patents

4-(4-phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones

Info

Publication number
ZA822987B
ZA822987B ZA822987A ZA822987A ZA822987B ZA 822987 B ZA822987 B ZA 822987B ZA 822987 A ZA822987 A ZA 822987A ZA 822987 A ZA822987 A ZA 822987A ZA 822987 B ZA822987 B ZA 822987B
Authority
ZA
South Africa
Prior art keywords
imidazol
dihydro
piperidinyl
acyl
ones
Prior art date
Application number
ZA822987A
Other languages
English (en)
Inventor
Martin J Grisar
Richard A Schnettler
Richard C Dage
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA822987B publication Critical patent/ZA822987B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hematology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA822987A 1981-05-04 1982-04-30 4-(4-phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones ZA822987B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/260,449 US4329471A (en) 1981-05-04 1981-05-04 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones

Publications (1)

Publication Number Publication Date
ZA822987B true ZA822987B (en) 1983-03-30

Family

ID=22989212

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA822987A ZA822987B (en) 1981-05-04 1982-04-30 4-(4-phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones

Country Status (10)

Country Link
US (1) US4329471A (xx)
EP (1) EP0064707B1 (xx)
JP (1) JPS57185281A (xx)
AT (1) ATE20891T1 (xx)
AU (1) AU546960B2 (xx)
CA (1) CA1167848A (xx)
DE (1) DE3272114D1 (xx)
ES (1) ES8308871A1 (xx)
IL (1) IL65667A (xx)
ZA (1) ZA822987B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
IT1230703B (it) * 1989-01-26 1991-10-29 Luso Farmaco Inst Derivati imidazolonici ad attivita' antiipertensiva, loro metodi di preparazione e composizioni farmaceutiche che li contengono.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them
US2441936A (en) * 1946-03-22 1948-05-18 Hoffmann La Roche Imidazolones and method of preparation
US2514380A (en) * 1946-12-26 1950-07-11 Hoffmann La Roche Diamines and method of production
US3303199A (en) * 1963-07-15 1967-02-07 Geigy Chem Corp Certain imidazolone derivatives and process for making same
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

Also Published As

Publication number Publication date
IL65667A0 (en) 1982-08-31
US4329471A (en) 1982-05-11
JPS57185281A (en) 1982-11-15
AU546960B2 (en) 1985-09-26
JPH0261475B2 (xx) 1990-12-20
ES511873A0 (es) 1983-10-01
EP0064707A1 (en) 1982-11-17
CA1167848A (en) 1984-05-22
DE3272114D1 (de) 1986-08-28
EP0064707B1 (en) 1986-07-23
ATE20891T1 (de) 1986-08-15
ES8308871A1 (es) 1983-10-01
IL65667A (en) 1985-12-31
AU8317682A (en) 1982-11-11

Similar Documents

Publication Publication Date Title
JPS57185281A (en) 4-(4-phenyl-1-piperidinyl)methyl-5-acyl-1,3- dihydro-2h-imidazole-2-one
AU546890B2 (en) 4-aminomethyl-5-acyl-1,3 dihydro-2h-imidazol-2-ones
DE3264545D1 (en) 5-(4-phenyl-1-piperidinyl)methyl-2,3-dihydro-2-oxo-1h-imidazole-4-carboxylic acid derivatives
AU6716981A (en) 4-(2,2-dialkyl-indane-1-ylidene)-piperidines
GB2097792B (en) 1,3-dihydro-2h-imidazol-2-ones
DE3271755D1 (en) 5-aminomethyl-2,3-dihydro-2-oxo-1h-imidazole-4-carboxylic acid derivatives
IT7920617V0 (it) Casella alveolare per la cottura di piastrelle.
SU1010844A1 (ru) 3,3-бис-(хлорметил)-тиетан в качестве компонента термостабилизирующей композиции полиэтилена высокого давления