ZA822297B - 5 fluoro pgi compounds - Google Patents

5 fluoro pgi compounds

Info

Publication number
ZA822297B
ZA822297B ZA822297A ZA822297A ZA822297B ZA 822297 B ZA822297 B ZA 822297B ZA 822297 A ZA822297 A ZA 822297A ZA 822297 A ZA822297 A ZA 822297A ZA 822297 B ZA822297 B ZA 822297B
Authority
ZA
South Africa
Prior art keywords
fluoro
compounds
pgi compounds
fluoro pgi
pgi
Prior art date
Application number
ZA822297A
Other languages
English (en)
Inventor
L Nysted
R Pappo
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of ZA822297B publication Critical patent/ZA822297B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
ZA822297A 1981-04-02 1982-04-02 5 fluoro pgi compounds ZA822297B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25053081A 1981-04-02 1981-04-02

Publications (1)

Publication Number Publication Date
ZA822297B true ZA822297B (en) 1983-04-27

Family

ID=22948130

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA822297A ZA822297B (en) 1981-04-02 1982-04-02 5 fluoro pgi compounds

Country Status (12)

Country Link
EP (1) EP0062303B1 (es)
JP (1) JPS57176978A (es)
AU (1) AU549367B2 (es)
CA (1) CA1215973A (es)
DE (1) DE3267651D1 (es)
DK (1) DK149682A (es)
ES (1) ES8306997A1 (es)
IE (1) IE52937B1 (es)
NO (2) NO157329C (es)
NZ (1) NZ200210A (es)
PT (1) PT74691B (es)
ZA (1) ZA822297B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation
JPS57200378A (en) * 1981-06-02 1982-12-08 Teijin Ltd Halogenated pgi2 and its preparation
US4670569A (en) * 1981-04-02 1987-06-02 G. D. Searle & Co. 5-fluoro-PGI2 compounds
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
US4579958A (en) * 1983-12-23 1986-04-01 G. D. Searle & Co. 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds
US4611065A (en) * 1985-01-25 1986-09-09 G. D. Searle & Co. Method for preparing 5-fluoroprostacyclins
US4616034A (en) * 1985-02-28 1986-10-07 G. D. Searle & Co. 15(R)-5-fluoroprostacyclins, pharmaceutical compositions and anti-thrombotic method of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097489A (en) * 1977-06-17 1978-06-27 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds
JPS56501319A (es) * 1979-10-10 1981-09-17
DE3176313D1 (en) * 1980-12-09 1987-08-20 Teijin Ltd Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof

Also Published As

Publication number Publication date
NO157329C (no) 1988-03-02
EP0062303A2 (en) 1982-10-13
EP0062303B1 (en) 1985-11-27
JPS57176978A (en) 1982-10-30
NO854442L (no) 1982-10-04
PT74691A (en) 1982-05-01
NO821108L (no) 1982-10-04
IE52937B1 (en) 1988-04-13
EP0062303A3 (en) 1982-11-10
ES511067A0 (es) 1983-06-16
DK149682A (da) 1982-10-03
IE820773L (en) 1982-10-02
DE3267651D1 (en) 1986-01-09
NO157329B (no) 1987-11-23
NZ200210A (en) 1985-10-11
AU8225882A (en) 1982-10-07
AU549367B2 (en) 1986-01-23
ES8306997A1 (es) 1983-06-16
PT74691B (en) 1983-10-26
CA1215973A (en) 1986-12-30

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