ZA81694B - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
ZA81694B
ZA81694B ZA00810694A ZA81694A ZA81694B ZA 81694 B ZA81694 B ZA 81694B ZA 00810694 A ZA00810694 A ZA 00810694A ZA 81694 A ZA81694 A ZA 81694A ZA 81694 B ZA81694 B ZA 81694B
Authority
ZA
South Africa
Prior art keywords
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
ZA00810694A
Other languages
English (en)
Inventor
A Fischli
Q Branca
A Szente
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA81694B publication Critical patent/ZA81694B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00810694A 1980-02-08 1981-02-02 Benzodiazepine derivatives ZA81694B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH103980 1980-02-08

Publications (1)

Publication Number Publication Date
ZA81694B true ZA81694B (en) 1982-03-31

Family

ID=4201027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00810694A ZA81694B (en) 1980-02-08 1981-02-02 Benzodiazepine derivatives

Country Status (8)

Country Link
US (1) US4361511A (xx)
EP (1) EP0033973B1 (xx)
JP (1) JPS56125375A (xx)
AU (1) AU545491B2 (xx)
CA (1) CA1145333A (xx)
DE (1) DE3160986D1 (xx)
DK (1) DK39581A (xx)
ZA (1) ZA81694B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1163266A (en) * 1980-07-31 1984-03-06 Albert E. Fischli Benzodiazepine derivatives
US5939412A (en) * 1992-06-26 1999-08-17 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
AU666318B2 (en) * 1991-06-28 1996-02-08 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
US6403578B1 (en) 1993-12-21 2002-06-11 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
MA23420A1 (fr) * 1994-01-07 1995-10-01 Smithkline Beecham Corp Antagonistes bicycliques de fibrinogene.
US6458784B1 (en) 1994-06-29 2002-10-01 Smithkline Beecham Corporation Vitronectin receptor antagonists
US5977101A (en) * 1995-06-29 1999-11-02 Smithkline Beecham Corporation Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity
JPWO2006132295A1 (ja) * 2005-06-09 2009-01-08 大日本住友製薬株式会社 アルドステロン受容体調節剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
BE787117A (fr) * 1971-08-04 1973-02-05 Hoffmann La Roche Derives de benzodiazepine
FR2252103A1 (en) * 1973-11-28 1975-06-20 Hoffmann La Roche Hydroxamino-substd. oxazolobenzodiazepines - sedatives, muscle relaxants and anti-convulsants
US4251444A (en) * 1980-04-07 1981-02-17 American Home Products Corporation Thiazepino-[4,3-b]-isoquinoline-1,5-dione derivatives and precursors

Also Published As

Publication number Publication date
AU545491B2 (en) 1985-07-18
EP0033973B1 (de) 1983-09-28
US4361511A (en) 1982-11-30
DE3160986D1 (en) 1983-11-03
DK39581A (da) 1981-08-09
EP0033973A1 (de) 1981-08-19
CA1145333A (en) 1983-04-26
AU6681981A (en) 1981-08-13
JPS56125375A (en) 1981-10-01

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