ZA796194B - New 2,2-dimethyl 19-nor steroid derivatives,process for their preparation,their application as medicaments and pharmaceutical compositions containing them - Google Patents

New 2,2-dimethyl 19-nor steroid derivatives,process for their preparation,their application as medicaments and pharmaceutical compositions containing them

Info

Publication number
ZA796194B
ZA796194B ZA00796194A ZA796194A ZA796194B ZA 796194 B ZA796194 B ZA 796194B ZA 00796194 A ZA00796194 A ZA 00796194A ZA 796194 A ZA796194 A ZA 796194A ZA 796194 B ZA796194 B ZA 796194B
Authority
ZA
South Africa
Prior art keywords
medicaments
dimethyl
preparation
new
application
Prior art date
Application number
ZA00796194A
Other languages
English (en)
Inventor
V Torelle
L Nedelec
R Fournex
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA796194B publication Critical patent/ZA796194B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
ZA00796194A 1978-12-13 1979-11-16 New 2,2-dimethyl 19-nor steroid derivatives,process for their preparation,their application as medicaments and pharmaceutical compositions containing them ZA796194B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7835046A FR2444047A1 (fr) 1978-12-13 1978-12-13 Nouveaux derives 2,2-dimethyl 19-nor steroides, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ZA796194B true ZA796194B (en) 1980-11-26

Family

ID=9216044

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00796194A ZA796194B (en) 1978-12-13 1979-11-16 New 2,2-dimethyl 19-nor steroid derivatives,process for their preparation,their application as medicaments and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4263290A (hu)
EP (2) EP0044575B1 (hu)
JP (1) JPS5585598A (hu)
AU (1) AU527582B2 (hu)
CA (1) CA1146531A (hu)
DK (1) DK527379A (hu)
ES (1) ES486791A0 (hu)
FI (1) FI70027C (hu)
FR (1) FR2444047A1 (hu)
HU (1) HU180931B (hu)
IE (1) IE49235B1 (hu)
PT (1) PT70575A (hu)
SU (1) SU1178325A3 (hu)
ZA (1) ZA796194B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012523A1 (en) * 1992-11-30 1994-06-09 Mallinckrodt Medical, Inc. Steroid-21-phosphate complex of technetium-99m
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
FR2917975B1 (fr) * 2007-06-26 2009-10-16 Ceva Sante Animale Sa Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains
US20090270356A1 (en) * 2008-04-28 2009-10-29 Ceva Sante Animale Sa Compositions and treatments of heart failure in non-human mammal animals
CA2813433C (en) 2010-10-27 2019-08-20 Dignity Health Trimegestone (tmg) for treatment of preterm birth

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138460A (en) * 1965-06-01 1969-01-01 Merck & Co Inc Steroid compounds
FR1476572A (fr) * 1965-09-13 1967-04-14 Gonènes synthétiques et leur procédé de préparation
FR2322606A1 (fr) * 1975-09-02 1977-04-01 Roussel Uclaf Nouveaux 2,2-dimethyl steroides, leur procede de preparation et leur application comme medicament
FR2364655A1 (fr) * 1976-09-17 1978-04-14 Roussel Uclaf Nouveaux 2,2-dimethyl 19-nor steroides, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
EP0012641A3 (en) 1980-09-17
AU5376279A (en) 1980-07-10
FI793847A (fi) 1980-06-14
EP0012641A2 (fr) 1980-06-25
EP0044575B1 (fr) 1984-03-21
JPS6337796B2 (hu) 1988-07-27
FI70027B (fi) 1986-01-31
PT70575A (fr) 1980-01-01
FR2444047A1 (fr) 1980-07-11
US4263290A (en) 1981-04-21
FR2444047B1 (hu) 1982-05-28
AU527582B2 (en) 1983-03-10
CA1146531A (fr) 1983-05-17
JPS5585598A (en) 1980-06-27
SU1178325A3 (ru) 1985-09-07
EP0044575A1 (fr) 1982-01-27
IE49235B1 (en) 1985-09-04
EP0012641B1 (fr) 1982-05-12
HU180931B (en) 1983-05-30
DK527379A (da) 1980-06-14
ES8102149A1 (es) 1980-12-16
FI70027C (fi) 1986-09-12
ES486791A0 (es) 1980-12-16
IE792420L (en) 1980-06-13

Similar Documents

Publication Publication Date Title
IL67920A0 (en) New derivatives of 3-keto delta 4,9,19-nor steroids,their preparation,their application as medicaments,the compositions containing them and the new intermediates obtained
IL57020A (en) Carbazolyl-(4)-oxypropanolamine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
DE2960178D1 (en) New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
DE2960954D1 (en) 1-aryloxy-3-nitratoalkylamino-2-propanols, process for their preparation and pharmaceutical compositions
PT69821A (en) Process for the preparation of new 5-phenylpyrazole derivatives the salts thereof and the pharmaceutical compositions containing same
DE2964209D1 (en) Spiro-furanohydantoin derivatives, process for their preparation and pharmaceutical compositions containing them
DE2962112D1 (en) Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them
IL57785A0 (en) New imidazoquinoxalines and their salts,process for their preparation,their use as medicaments and the pharmaceutical compositions containing them
IL56808A0 (en) 1-oxo-1h-pyrimido(6,1)benztheazole derivatives,process forthe preparation thereof and pharmaceutical compositions containing the same
IL57213A (en) Substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof,and pharmaceutical compositions containing them
IL57920A0 (en) 1-phenylpiperazine derivatives,their preparation and pharmaceutical compositions containing them
IL56856A (en) 4,5-diaryl-pyrrole derivatives,their preparation and pharmaceutical compositions containing them
ZA796194B (en) New 2,2-dimethyl 19-nor steroid derivatives,process for their preparation,their application as medicaments and pharmaceutical compositions containing them
ZA793682B (en) New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
IL54111A (en) 3,6-disubstituted-1,2,4-triazine-5-one-derivatives,process for their preparation and pharmaceutical compositions containing them
ZA793967B (en) New acetylene derivatives of androst-4-ene,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them
DE2861570D1 (en) 17 alpha-aryl or 17 alpha-heteroaryl steroids, process for their preparation, their use as medicines and pharmaceutical compositions containing them
DE2967070D1 (en) 11,17-substituted pregnanes, their preparation and application for the preparation of pharmaceutical compositions
IL59857A0 (en) New derivatives of 1 ,25-dihydroxy-cholecalciferol,process for preparing it,its use as a medicament and the pharmaceutical compositions containing it
DE3166459D1 (en) New 8-alpha-oestra-1,3,5(10)-triene derivatives, processes for their preparation and pharmaceutical compositions
ZA794631B (en) New 1-methyl-4-piperidinol esters,process for their preparation and pharmaceutical compositions containing them
IL61176A0 (en) 1,2,4-oxadiazine derivatives,process for their preparation and pharmaceutical compositions containing them
IL50430A0 (en) New 2,4-diamino-5-benzylpyrimidines process for their preparation and pharmaceutical compositions containing these compounds
DE2960521D1 (en) 2-amino-3a,4,5,6-tetrahydroperimidine derivatives, medicaments containing them and process for their preparation
DE2962843D1 (en) Substituted-19-nor-pregn-4-ene-3,20-dione derivatives, process for their preparation and pharmaceutical compositions containing them