ZA782454B - Benzylpyrimidines and process for the preparation thereof - Google Patents

Benzylpyrimidines and process for the preparation thereof

Info

Publication number
ZA782454B
ZA782454B ZA00782454A ZA782454A ZA782454B ZA 782454 B ZA782454 B ZA 782454B ZA 00782454 A ZA00782454 A ZA 00782454A ZA 782454 A ZA782454 A ZA 782454A ZA 782454 B ZA782454 B ZA 782454B
Authority
ZA
South Africa
Prior art keywords
benzylpyrimidines
preparation
Prior art date
Application number
ZA00782454A
Other languages
English (en)
Inventor
I Kompis
A Wick
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA782454B publication Critical patent/ZA782454B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00782454A 1977-05-05 1978-04-28 Benzylpyrimidines and process for the preparation thereof ZA782454B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77268A LU77268A1 (xx) 1977-05-05 1977-05-05

Publications (1)

Publication Number Publication Date
ZA782454B true ZA782454B (en) 1979-04-25

Family

ID=19728558

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00782454A ZA782454B (en) 1977-05-05 1978-04-28 Benzylpyrimidines and process for the preparation thereof

Country Status (13)

Country Link
US (1) US4191758A (xx)
JP (1) JPS53137977A (xx)
AU (1) AU3555378A (xx)
BE (1) BE866652A (xx)
CA (1) CA1075694A (xx)
DE (1) DE2819211A1 (xx)
DK (1) DK195478A (xx)
FR (1) FR2389612A1 (xx)
GB (1) GB1581015A (xx)
LU (1) LU77268A1 (xx)
NL (1) NL7804769A (xx)
SE (1) SE7805187L (xx)
ZA (1) ZA782454B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2095518A1 (en) * 1990-11-14 1992-05-15 Jeffrey M. Blaney Specific inhibition of dihydrofolate reductase and compounds therefor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996356A (en) * 1969-07-02 1976-12-07 Hoffmann-La Roche Inc. Composition containing 5-sulfanilamido-3,4-dimethylisoxazole and a trimethoxybenzyl pyrimidine
BE795023A (fr) * 1972-02-07 1973-08-06 Hoffmann La Roche Nouvelles benzylpyrimidines
US3985876A (en) * 1973-01-05 1976-10-12 Burroughs Wellcome Co. Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine
US4033962A (en) * 1975-06-26 1977-07-05 Hoffman-La Roche Inc. 2,4-Diamino-pyrimidine derivatives and processes

Also Published As

Publication number Publication date
CA1075694A (en) 1980-04-15
BE866652A (fr) 1978-11-03
JPS53137977A (en) 1978-12-01
GB1581015A (en) 1980-12-10
SE7805187L (sv) 1978-11-06
NL7804769A (nl) 1978-11-07
LU77268A1 (xx) 1979-01-18
FR2389612A1 (xx) 1978-12-01
DE2819211A1 (de) 1978-11-16
DK195478A (da) 1978-11-06
US4191758A (en) 1980-03-04
AU3555378A (en) 1979-11-01

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