ZA728428B - A process for the preparation of benzylpyrimidines - Google Patents

A process for the preparation of benzylpyrimidines

Info

Publication number
ZA728428B
ZA728428B ZA728428A ZA728428A ZA728428B ZA 728428 B ZA728428 B ZA 728428B ZA 728428 A ZA728428 A ZA 728428A ZA 728428 A ZA728428 A ZA 728428A ZA 728428 B ZA728428 B ZA 728428B
Authority
ZA
South Africa
Prior art keywords
benzylpyrimidines
preparation
Prior art date
Application number
ZA728428A
Inventor
J Naiman
M Nussim
E Levy
Original Assignee
Plantex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plantex Ltd filed Critical Plantex Ltd
Publication of ZA728428B publication Critical patent/ZA728428B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
ZA728428A 1971-12-01 1972-11-28 A process for the preparation of benzylpyrimidines ZA728428B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL38276A IL38276A (en) 1971-12-01 1971-12-01 Process for the preparation of 2,4-diamino-5-substituted benzylpyrimidines

Publications (1)

Publication Number Publication Date
ZA728428B true ZA728428B (en) 1973-10-31

Family

ID=11046229

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA728428A ZA728428B (en) 1971-12-01 1972-11-28 A process for the preparation of benzylpyrimidines

Country Status (8)

Country Link
AT (1) AT331249B (en)
AU (1) AU476925B2 (en)
CA (1) CA989840A (en)
CH (1) CH584692A5 (en)
DE (1) DE2258238A1 (en)
IL (1) IL38276A (en)
NL (1) NL7216163A (en)
ZA (1) ZA728428B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5025575A (en) * 1973-07-03 1975-03-18
FR2283129A1 (en) * 1974-03-01 1976-03-26 Wellcome Found 2,4-Diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine prodn - strong bacteri-cide, for increasing activity of sulpha drugs
GR71725B (en) * 1977-11-10 1983-06-22 Hoffmann La Roche
CN105294574B (en) * 2015-11-25 2018-06-29 湖南湘易康制药有限公司 A kind of synthetic method of trimethoprim

Also Published As

Publication number Publication date
CA989840A (en) 1976-05-25
ATA1008872A (en) 1975-11-15
AT331249B (en) 1976-08-10
NL7216163A (en) 1973-06-05
DE2258238A1 (en) 1973-06-07
IL38276A (en) 1976-09-30
AU476925B2 (en) 1976-10-07
IL38276A0 (en) 1972-02-29
CH584692A5 (en) 1977-02-15
AU4935772A (en) 1974-05-30

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