AU476925B2 - A process forthe preparation of benzylpyrimidines - Google Patents

A process forthe preparation of benzylpyrimidines

Info

Publication number
AU476925B2
AU476925B2 AU49357/72A AU4935772A AU476925B2 AU 476925 B2 AU476925 B2 AU 476925B2 AU 49357/72 A AU49357/72 A AU 49357/72A AU 4935772 A AU4935772 A AU 4935772A AU 476925 B2 AU476925 B2 AU 476925B2
Authority
AU
Australia
Prior art keywords
benzylpyrimidines
process forthe
forthe preparation
preparation
forthe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU49357/72A
Other versions
AU4935772A (en
Inventor
Gussin Ezra Levy Jacob Naiman Manasse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Plantex Ltd
Original Assignee
Plantex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plantex Ltd filed Critical Plantex Ltd
Publication of AU4935772A publication Critical patent/AU4935772A/en
Application granted granted Critical
Publication of AU476925B2 publication Critical patent/AU476925B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU49357/72A 1971-12-01 1972-11-28 A process forthe preparation of benzylpyrimidines Expired AU476925B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ILIL38276 1971-12-01
IL38276A IL38276A (en) 1971-12-01 1971-12-01 Process for the preparation of 2,4-diamino-5-substituted benzylpyrimidines
ILIL38412 1971-12-20

Publications (2)

Publication Number Publication Date
AU4935772A AU4935772A (en) 1974-05-30
AU476925B2 true AU476925B2 (en) 1976-10-07

Family

ID=11046229

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49357/72A Expired AU476925B2 (en) 1971-12-01 1972-11-28 A process forthe preparation of benzylpyrimidines

Country Status (8)

Country Link
AT (1) AT331249B (en)
AU (1) AU476925B2 (en)
CA (1) CA989840A (en)
CH (1) CH584692A5 (en)
DE (1) DE2258238A1 (en)
IL (1) IL38276A (en)
NL (1) NL7216163A (en)
ZA (1) ZA728428B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5025575A (en) * 1973-07-03 1975-03-18
FR2283129A1 (en) * 1974-03-01 1976-03-26 Wellcome Found 2,4-Diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine prodn - strong bacteri-cide, for increasing activity of sulpha drugs
GR71725B (en) * 1977-11-10 1983-06-22 Hoffmann La Roche
CN105294574B (en) * 2015-11-25 2018-06-29 湖南湘易康制药有限公司 A kind of synthetic method of trimethoprim

Also Published As

Publication number Publication date
IL38276A0 (en) 1972-02-29
CA989840A (en) 1976-05-25
IL38276A (en) 1976-09-30
AT331249B (en) 1976-08-10
ZA728428B (en) 1973-10-31
AU4935772A (en) 1974-05-30
CH584692A5 (en) 1977-02-15
DE2258238A1 (en) 1973-06-07
NL7216163A (en) 1973-06-05
ATA1008872A (en) 1975-11-15

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