ZA721297B - Process of separating optical,geometric,structural isomers and the compounds used for - Google Patents

Process of separating optical,geometric,structural isomers and the compounds used for

Info

Publication number
ZA721297B
ZA721297B ZA721297A ZA721297A ZA721297B ZA 721297 B ZA721297 B ZA 721297B ZA 721297 A ZA721297 A ZA 721297A ZA 721297 A ZA721297 A ZA 721297A ZA 721297 B ZA721297 B ZA 721297B
Authority
ZA
South Africa
Prior art keywords
geometric
compounds used
structural isomers
separating optical
separating
Prior art date
Application number
ZA721297A
Other languages
English (en)
Inventor
R Viterbo
J Jacques
Original Assignee
Richardson Merrell Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Spa filed Critical Richardson Merrell Spa
Publication of ZA721297B publication Critical patent/ZA721297B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
ZA721297A 1971-03-18 1972-02-28 Process of separating optical,geometric,structural isomers and the compounds used for ZA721297B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49167/71A IT951631B (it) 1971-03-18 1971-03-18 Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi

Publications (1)

Publication Number Publication Date
ZA721297B true ZA721297B (en) 1973-03-28

Family

ID=11269830

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA721297A ZA721297B (en) 1971-03-18 1972-02-28 Process of separating optical,geometric,structural isomers and the compounds used for

Country Status (18)

Country Link
US (1) US3848030A (cs)
JP (1) JPS5547013B1 (cs)
AU (1) AU462431B2 (cs)
BE (1) BE780887A (cs)
CA (1) CA961500A (cs)
CH (1) CH576921A5 (cs)
DE (1) DE2212660C3 (cs)
DK (1) DK139944B (cs)
ES (1) ES400862A1 (cs)
FR (1) FR2129741A5 (cs)
GB (1) GB1360946A (cs)
IL (1) IL38860A (cs)
IT (1) IT951631B (cs)
NL (1) NL7203574A (cs)
NO (1) NO136357C (cs)
PH (1) PH10768A (cs)
SE (1) SE409323B (cs)
ZA (1) ZA721297B (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143028A (en) * 1977-12-05 1979-03-06 Ciba-Geigy Corporation Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions
US5288914A (en) * 1984-08-27 1994-02-22 The Dow Chemical Company Poly(arylcyclobutenes)
NL8403224A (nl) * 1984-10-24 1986-05-16 Oce Andeno Bv Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
DE3940765A1 (de) * 1989-12-09 1991-06-13 Hoechst Ag Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester
MX9605611A (es) * 1994-05-16 1998-05-31 Merrell Pharma Inc Procedimiento y sales diastereomericas utiles para la resolucion optica de a-(4-(1,1-dimetiletil)fenil)-4-(hidroxidifenil-metil)-1-pipe ridinbutanol racemico y compuestos derivados.
JP4725757B2 (ja) * 1999-03-24 2011-07-13 東ソー株式会社 ビナフトールリン酸誘導体及びその利用
DE60008807T2 (de) 1999-03-24 2005-01-13 Tosoh Corp., Shinnanyo Binaphtol-monophosphorsäurederivate und deren Verwendung
WO2001030763A1 (en) * 1999-10-22 2001-05-03 Takeda Chemical Industries, Ltd. Process for producing optically active naphthalene derivative and optical resolver therefor
EP1229019A4 (en) * 1999-11-10 2004-08-18 Takeda Chemical Industries Ltd METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE, CYCLIC ENAMINONE DERIVATIVES
US6391926B2 (en) 2000-03-13 2002-05-21 Tosoh Corporation Optically active phosphate derivative
NZ530491A (en) 2001-07-09 2007-08-31 Repros Therapeutics Inc Composition comprising 0-29% cis-clomiphene and 79-100% trans-clomiphene testosterone deficiency in men
CN100410234C (zh) * 2003-04-25 2008-08-13 东亚合成株式会社 利用手性布朗斯台德酸的不对称合成用催化剂和使用该催化剂的不对称合成方法
US7229557B2 (en) * 2004-02-04 2007-06-12 Konec, Inc. Method to separate stereoisomers
EP2486032A4 (en) * 2009-10-09 2013-03-27 Hetero Research Foundation RACEMATSPALTUNG SUBSTITUTED 2- (2-PYRIDINYLMETHYLSULFINYL) -1H-BENZIMIDAZOLE
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
UA113324C2 (xx) 2012-08-21 2017-01-10 Склади транс-кломіфену та їх застосування
WO2014070523A1 (en) 2012-11-02 2014-05-08 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
JP2017507961A (ja) * 2014-03-11 2017-03-23 レプロス セラピューティクス インコーポレイティド 単一の溶媒を用いるクロミフェン合成
DK3171866T3 (da) 2014-07-24 2020-11-09 Aspen Park Pharmaceuticals Inc Behandling af androgen deprivationsterapi-inducerede hedeture og knogletab ved anvendelse af cis-clomiphen
EP3015453B1 (en) 2014-10-28 2016-10-12 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of Clomiphene
EP3015454A1 (en) 2014-10-28 2016-05-04 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Stable solid form of trans-Clomiphene citrate
CA2989364C (en) 2016-04-22 2021-07-20 F.I.S. - Fabbrica Italiana Sintetici S.P.A. Process for the preparation of enclomiphene citrate having needle shaped crystal habit.
CA3073836A1 (en) 2017-09-11 2019-03-14 Atossa Therapeutics, Inc. Methods for making and using endoxifen
FR3082842A1 (fr) * 2018-06-21 2019-12-27 Veru Inc. Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci
WO2021003433A1 (en) 2019-07-03 2021-01-07 Atossa Therapeutics, Inc. Sustained release compositions of endoxifen
CA3098725A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Zuclpomiphene salts and crystalline forms thereof
CA3098552A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Processes for the preparation of zuclomiphene and intermediates thereof
CA3105944A1 (en) 2020-01-22 2021-07-22 Apotex Inc. Crystalline forms of zuclomiphene citrate
EP3907213A1 (en) 2020-05-04 2021-11-10 Pcas Processes for the production of isomerically pure or enriched cis-clomiphene
US11578025B2 (en) 2020-10-19 2023-02-14 Apotex Inc. Processes for the preparation of zuclomiphene intermediates

Also Published As

Publication number Publication date
GB1360946A (en) 1974-07-24
DK139944B (da) 1979-05-21
CA961500A (en) 1975-01-21
JPS5547013B1 (cs) 1980-11-27
DE2212660A1 (de) 1972-09-28
AU3961172A (en) 1973-09-06
NO136357C (no) 1977-08-24
US3848030A (en) 1974-11-12
SE409323B (sv) 1979-08-13
ES400862A1 (es) 1976-04-16
NO136357B (cs) 1977-05-16
IL38860A0 (en) 1972-04-27
AU462431B2 (en) 1975-06-09
DK139944C (cs) 1979-10-22
CH576921A5 (cs) 1976-06-30
BE780887A (fr) 1972-07-17
IL38860A (en) 1975-06-25
DE2212660C3 (de) 1981-09-24
NL7203574A (cs) 1972-09-20
FR2129741A5 (cs) 1972-10-27
IT951631B (it) 1973-07-10
DE2212660B2 (de) 1980-07-10
PH10768A (en) 1977-09-05

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