ZA714729B - Novel benzcyclobutene derivatives - Google Patents

Novel benzcyclobutene derivatives

Info

Publication number
ZA714729B
ZA714729B ZA714729A ZA714729A ZA714729B ZA 714729 B ZA714729 B ZA 714729B ZA 714729 A ZA714729 A ZA 714729A ZA 714729 A ZA714729 A ZA 714729A ZA 714729 B ZA714729 B ZA 714729B
Authority
ZA
South Africa
Prior art keywords
benzcyclobutene
derivatives
novel
novel benzcyclobutene
benzcyclobutene derivatives
Prior art date
Application number
ZA714729A
Other languages
English (en)
Inventor
H Panneman
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of ZA714729B publication Critical patent/ZA714729B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/16—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ZA714729A 1970-08-07 1971-07-16 Novel benzcyclobutene derivatives ZA714729B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7011683A NL7011683A (enExample) 1970-08-07 1970-08-07

Publications (1)

Publication Number Publication Date
ZA714729B true ZA714729B (en) 1972-04-26

Family

ID=19810731

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA714729A ZA714729B (en) 1970-08-07 1971-07-16 Novel benzcyclobutene derivatives

Country Status (9)

Country Link
US (1) US3804898A (enExample)
AU (1) AU3153171A (enExample)
BE (1) BE771055A (enExample)
CA (1) CA971970A (enExample)
DE (1) DE2139526A1 (enExample)
FR (1) FR2102106A1 (enExample)
HU (1) HU162459B (enExample)
NL (1) NL7011683A (enExample)
ZA (1) ZA714729B (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013682A (en) * 1973-08-03 1977-03-22 Akzona Incorporated N-hydroxy-amidine compounds
NL7315350A (nl) * 1973-11-09 1975-05-13 Akzo Nv Nieuwe aminoguanidine verbindingen.
US4101675A (en) * 1973-11-09 1978-07-18 Akzona Incorporated Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method
NL7407469A (nl) * 1974-06-01 1975-12-03 Akzo Nv Nieuwe amidinohydrazonverbindingen.
US5478863A (en) * 1986-07-10 1995-12-26 State Of Oregon, Oregon Health Sciences University Of Oregon Substituted guanidines having high binding to the sigma receptor and the use thereof
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
ES2181668T3 (es) 1990-03-02 2003-03-01 Oregon State Guanidinas tri- y tetra-substituidas y su uso como antagonistas de aminoacido excitador.
US5336689A (en) * 1990-03-02 1994-08-09 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
EP0532642A1 (en) * 1990-05-25 1993-03-24 STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON Substituted guanidines having high binding to the sigma receptor and the use thereof
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
ATE186047T1 (de) * 1991-02-08 1999-11-15 Cambridge Neuroscience Res Substituierte guanidine und derivate hiervon als modulatoren der freisetzung von neurotransmittern und neue methode zur identifizierung von inhibitoren der neurotransmitter-freisetzung
CN1188121C (zh) * 1993-05-27 2005-02-09 剑桥神经科学公司 治疗性取代的胍类
KR100424523B1 (ko) * 1993-11-23 2004-09-30 캠브리지 뉴로사이언스, 인코포레이티드 치료용의치환된구아니딘
US5877218A (en) 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
AU1867095A (en) * 1994-01-10 1995-08-01 Technion Research & Development Foundation Ltd. 1-aminoindan derivatives and compositions thereof
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
JPH09509156A (ja) 1994-02-03 1997-09-16 ケンブリッジ・ニューロサイエンス・インコーポレーテッド 治療用グアニジン類
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
IL130528A (en) 1996-12-18 2004-12-15 Teva Pharma Aminoindan derivatives, pharmaceutical compositions comprising them and uses thereof
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
CN103142570A (zh) * 2005-12-09 2013-06-12 耶路撒冷希伯来大学伊森姆研究发展公司 低剂量Ladostigil 用于神经保护的用途
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof

Also Published As

Publication number Publication date
US3804898A (en) 1974-04-16
FR2102106A1 (fr) 1972-04-07
HU162459B (enExample) 1973-02-28
AU3153171A (en) 1973-01-25
BE771055A (nl) 1971-12-16
CA971970A (en) 1975-07-29
DE2139526A1 (enExample) 1972-03-09
NL7011683A (enExample) 1972-02-09

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