ZA202203272B - Anti-stem cell factor antibodies and methods of use thereof - Google Patents

Anti-stem cell factor antibodies and methods of use thereof

Info

Publication number
ZA202203272B
ZA202203272B ZA2022/03272A ZA202203272A ZA202203272B ZA 202203272 B ZA202203272 B ZA 202203272B ZA 2022/03272 A ZA2022/03272 A ZA 2022/03272A ZA 202203272 A ZA202203272 A ZA 202203272A ZA 202203272 B ZA202203272 B ZA 202203272B
Authority
ZA
South Africa
Prior art keywords
methods
stem cell
cell factor
factor antibodies
antibodies
Prior art date
Application number
ZA2022/03272A
Other languages
English (en)
Inventor
Martin Phillips
Original Assignee
Opsidio Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opsidio Llc filed Critical Opsidio Llc
Publication of ZA202203272B publication Critical patent/ZA202203272B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2022/03272A 2019-09-16 2022-03-18 Anti-stem cell factor antibodies and methods of use thereof ZA202203272B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962900927P 2019-09-16 2019-09-16
PCT/US2020/050973 WO2021055408A1 (en) 2019-09-16 2020-09-16 Anti-stem cell factor antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
ZA202203272B true ZA202203272B (en) 2022-12-21

Family

ID=74868426

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2022/03272A ZA202203272B (en) 2019-09-16 2022-03-18 Anti-stem cell factor antibodies and methods of use thereof

Country Status (28)

Country Link
US (6) US20220324957A1 (enExample)
EP (3) EP4650367A3 (enExample)
JP (4) JP7717687B2 (enExample)
KR (1) KR20220079561A (enExample)
CN (2) CN114729036B (enExample)
AR (1) AR119979A1 (enExample)
AU (2) AU2020351138A1 (enExample)
BR (1) BR112022004776A2 (enExample)
CA (2) CA3154648A1 (enExample)
CL (1) CL2022000633A1 (enExample)
CO (1) CO2022003661A2 (enExample)
DK (1) DK4031569T3 (enExample)
DO (1) DOP2022000058A (enExample)
EC (1) ECSP22022676A (enExample)
ES (1) ES3053942T3 (enExample)
FI (1) FI4031569T3 (enExample)
IL (1) IL291385A (enExample)
MX (1) MX2022003159A (enExample)
PE (1) PE20230090A1 (enExample)
PH (1) PH12022550647A1 (enExample)
PL (1) PL4031569T3 (enExample)
PT (1) PT4031569T (enExample)
SA (1) SA522431966B1 (enExample)
TW (1) TWI875812B (enExample)
UA (1) UA129546C2 (enExample)
UY (1) UY38883A (enExample)
WO (2) WO2021055408A1 (enExample)
ZA (1) ZA202203272B (enExample)

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US20220324957A1 (en) 2019-09-16 2022-10-13 Opsidio, LLC Anti-stem cell factor antibodies and methods of use thereof in renal disease
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WO2026079764A1 (ko) * 2024-10-10 2026-04-16 아주대학교산학협력단 마우스 scf를 중화하는 항체 및 이의 용도

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Also Published As

Publication number Publication date
US20240076367A1 (en) 2024-03-07
UY38883A (es) 2021-04-30
TW202124434A (zh) 2021-07-01
EP4031569A4 (en) 2023-10-18
JP2022548646A (ja) 2022-11-21
CA3154649A1 (en) 2021-03-25
EP4031176A4 (en) 2023-11-29
DOP2022000058A (es) 2022-08-31
UA129546C2 (uk) 2025-05-28
US20220340655A1 (en) 2022-10-27
DK4031569T3 (da) 2025-11-17
US20230019680A1 (en) 2023-01-19
CN118561997A (zh) 2024-08-30
PL4031569T3 (pl) 2026-02-16
FI4031569T3 (fi) 2025-11-14
MX2022003159A (es) 2022-04-07
US11939373B2 (en) 2024-03-26
ES3053942T3 (en) 2026-01-28
PH12022550647A1 (en) 2023-03-27
US20210079084A1 (en) 2021-03-18
TWI875812B (zh) 2025-03-11
EP4650367A2 (en) 2025-11-19
BR112022004776A2 (pt) 2022-06-21
SA522431966B1 (ar) 2025-05-18
JP7717687B2 (ja) 2025-08-04
WO2021055409A1 (en) 2021-03-25
JP2022547733A (ja) 2022-11-15
EP4031176A1 (en) 2022-07-27
PE20230090A1 (es) 2023-01-16
AU2020351138A1 (en) 2022-03-31
CL2022000633A1 (es) 2022-11-11
AU2020348295A1 (en) 2022-04-07
CO2022003661A2 (es) 2022-04-08
EP4031569A1 (en) 2022-07-27
AR119979A1 (es) 2022-01-26
WO2021055408A1 (en) 2021-03-25
EP4031569B1 (en) 2025-08-20
CN114729036A (zh) 2022-07-08
CA3154648A1 (en) 2021-03-25
US20260193336A1 (en) 2026-07-09
US12410246B2 (en) 2025-09-09
KR20220079561A (ko) 2022-06-13
JP7698635B2 (ja) 2025-06-25
TW202523696A (zh) 2025-06-16
ECSP22022676A (es) 2022-05-31
IL291385A (en) 2022-05-01
CN114729036B (zh) 2024-07-02
JP2025125563A (ja) 2025-08-27
PT4031569T (pt) 2025-11-12
JP2025165991A (ja) 2025-11-05
EP4650367A3 (en) 2026-03-04
US20220324957A1 (en) 2022-10-13

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