ZA201209298B - Hydroxyalkyl benzyl pyrazoles,and use thereof for the treatment of hyperproliferative and angiogenic diseases - Google Patents
Hydroxyalkyl benzyl pyrazoles,and use thereof for the treatment of hyperproliferative and angiogenic diseasesInfo
- Publication number
- ZA201209298B ZA201209298B ZA2012/09298A ZA201209298A ZA201209298B ZA 201209298 B ZA201209298 B ZA 201209298B ZA 2012/09298 A ZA2012/09298 A ZA 2012/09298A ZA 201209298 A ZA201209298 A ZA 201209298A ZA 201209298 B ZA201209298 B ZA 201209298B
- Authority
- ZA
- South Africa
- Prior art keywords
- hyperproliferative
- treatment
- angiogenic diseases
- hydroxyalkyl
- pyrazoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10004854 | 2010-05-08 | ||
| PCT/EP2011/057019 WO2011141325A1 (en) | 2010-05-08 | 2011-05-03 | Hydroxyalkyl benzyl pyrazoles, and use thereof for the treatment of hyperproliferative and angiogenic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201209298B true ZA201209298B (en) | 2014-05-28 |
Family
ID=44243203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2012/09298A ZA201209298B (en) | 2010-05-08 | 2012-12-07 | Hydroxyalkyl benzyl pyrazoles,and use thereof for the treatment of hyperproliferative and angiogenic diseases |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2569309A1 (en) |
| JP (1) | JP2013530139A (en) |
| KR (1) | KR20130108998A (en) |
| CN (1) | CN103003266A (en) |
| AU (1) | AU2011252222A1 (en) |
| BR (1) | BR112012028652A2 (en) |
| CA (1) | CA2798374A1 (en) |
| IL (1) | IL222850A0 (en) |
| MX (1) | MX2012012905A (en) |
| RU (1) | RU2012152800A (en) |
| WO (1) | WO2011141325A1 (en) |
| ZA (1) | ZA201209298B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014031928A2 (en) * | 2012-08-24 | 2014-02-27 | Philip Jones | Heterocyclic modulators of hif activity for treatment of disease |
| WO2014031933A2 (en) | 2012-08-24 | 2014-02-27 | Philip Jones | Heterocyclic modulators of hif activity for treatment of disease |
| ES2691643T3 (en) | 2012-08-24 | 2018-11-28 | Board Of Regents, The University Of Texas System | Heterocyclic modulators of HIF activity for the treatment of diseases |
| ES2726648T3 (en) | 2014-02-25 | 2019-10-08 | Univ Texas | Salts of heterocyclic modulators of HIF activity for the treatment of diseases |
| CN107235873B (en) * | 2017-07-04 | 2018-11-06 | 中节能万润股份有限公司 | A kind of preparation method of mesna |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060194807A1 (en) | 2003-04-03 | 2006-08-31 | Cosford Nicholas D P | Di-aryl substituted pyrazole modulators of metabotropic glutamate receptor-5 |
| WO2005030121A2 (en) | 2003-06-30 | 2005-04-07 | Hif Bio, Inc. | Compounds, compositions and methods |
| WO2007065010A2 (en) | 2005-12-02 | 2007-06-07 | Hif Bio, Inc. | Anti-angiogenesis compounds |
| BRPI0812361A2 (en) | 2007-05-18 | 2015-02-03 | Bayer Schering Pharma Ag | Heteroaryl PIRAZOL DERIVATIVES SUBSTITUTED FOR THE TREATMENT OF ANGIOGENESE DISORDERS AND HYPERPROLIFERATIVE DISEASES |
| DE102008057344A1 (en) * | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Aminoalkyl-substituted aryl compounds and their use |
| ES2538301T3 (en) * | 2008-11-14 | 2015-06-18 | Bayer Intellectual Property Gmbh | Aryl compounds with heterocyclic substituents as HIF inhibitors |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
| ES2405054T3 (en) | 2009-01-23 | 2013-05-30 | Bristol-Myers Squibb Company | Pyrazole-1,2,4-oxadiazole derivatives as sphingosine-1-phosphate agonists |
-
2011
- 2011-05-03 AU AU2011252222A patent/AU2011252222A1/en not_active Abandoned
- 2011-05-03 CN CN2011800338366A patent/CN103003266A/en active Pending
- 2011-05-03 KR KR1020127032070A patent/KR20130108998A/en not_active Application Discontinuation
- 2011-05-03 JP JP2013509504A patent/JP2013530139A/en not_active Withdrawn
- 2011-05-03 EP EP11716947A patent/EP2569309A1/en not_active Withdrawn
- 2011-05-03 BR BR112012028652A patent/BR112012028652A2/en not_active IP Right Cessation
- 2011-05-03 CA CA2798374A patent/CA2798374A1/en not_active Abandoned
- 2011-05-03 WO PCT/EP2011/057019 patent/WO2011141325A1/en active Application Filing
- 2011-05-03 MX MX2012012905A patent/MX2012012905A/en unknown
- 2011-05-03 RU RU2012152800/04A patent/RU2012152800A/en not_active Application Discontinuation
-
2012
- 2012-11-05 IL IL222850A patent/IL222850A0/en unknown
- 2012-12-07 ZA ZA2012/09298A patent/ZA201209298B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012028652A2 (en) | 2016-08-09 |
| RU2012152800A (en) | 2014-06-20 |
| EP2569309A1 (en) | 2013-03-20 |
| CA2798374A1 (en) | 2011-11-17 |
| MX2012012905A (en) | 2012-12-17 |
| CN103003266A (en) | 2013-03-27 |
| JP2013530139A (en) | 2013-07-25 |
| KR20130108998A (en) | 2013-10-07 |
| WO2011141325A1 (en) | 2011-11-17 |
| AU2011252222A1 (en) | 2012-12-06 |
| IL222850A0 (en) | 2012-12-31 |
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