ZA201209240B - Topical ophthalmic suspensions containing tobramyccin and dexamethasone - Google Patents

Topical ophthalmic suspensions containing tobramyccin and dexamethasone

Info

Publication number
ZA201209240B
ZA201209240B ZA2012/09240A ZA201209240A ZA201209240B ZA 201209240 B ZA201209240 B ZA 201209240B ZA 2012/09240 A ZA2012/09240 A ZA 2012/09240A ZA 201209240 A ZA201209240 A ZA 201209240A ZA 201209240 B ZA201209240 B ZA 201209240B
Authority
ZA
South Africa
Prior art keywords
tobramyccin
dexamethasone
suspensions containing
topical ophthalmic
ophthalmic suspensions
Prior art date
Application number
ZA2012/09240A
Inventor
Bhagwati P Karba
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of ZA201209240B publication Critical patent/ZA201209240B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA2012/09240A 2010-06-23 2012-12-06 Topical ophthalmic suspensions containing tobramyccin and dexamethasone ZA201209240B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2010/039618 WO2011162752A1 (en) 2010-06-23 2010-06-23 Topical ophthalmic suspensions containing tobramycin and dexamethasone

Publications (1)

Publication Number Publication Date
ZA201209240B true ZA201209240B (en) 2014-02-26

Family

ID=44080140

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/09240A ZA201209240B (en) 2010-06-23 2012-12-06 Topical ophthalmic suspensions containing tobramyccin and dexamethasone

Country Status (10)

Country Link
EP (1) EP2585037A1 (en)
JP (1) JP5728082B2 (en)
KR (1) KR20130094280A (en)
CN (1) CN102946855B (en)
AU (1) AU2010356098B2 (en)
BR (1) BR112012033052A2 (en)
CA (1) CA2801731A1 (en)
MX (1) MX2012015051A (en)
WO (1) WO2011162752A1 (en)
ZA (1) ZA201209240B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201208080D0 (en) * 2012-05-09 2012-06-20 Norton Healthcare Ltd Tobramycin formulation
JP6527315B2 (en) * 2014-08-08 2019-06-05 Dsp五協フード&ケミカル株式会社 Fast-dissolving thickener, thickener for people with dysphagia and dysphagia, food and drink for patients with dysphagia and dysphagia
CN109260219B (en) * 2018-11-30 2021-03-09 山东省药学科学院 Articular cavity injection preparation and application thereof
IT202000002296A1 (en) * 2020-02-06 2021-08-06 Sifi Spa Topical ophthalmic formulations based on xanthan with reduced dosage
IT202200000821A1 (en) * 2022-01-19 2023-07-19 Sifi Spa TOPICAL OPHTHALMIC FORMULATIONS BASED ON XANTHANE WITH REDUCED DOSAGE
CN115006412B (en) * 2022-05-20 2023-11-10 北京诺康达医药科技股份有限公司 Compound tobramycin eye drops and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US5149694A (en) 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and dexamethasone for topical ophthalmic use
EP1348427B1 (en) * 1997-07-29 2008-04-09 Alcon Laboratories, Inc. Ophthalmic compositions containing galactomannan polymers and borate
US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
DE69909768T2 (en) * 1998-04-07 2004-06-17 Alcon Manufacturing Ltd., Fort Worth XANTHAN GUM CONTAINING YELLOWING OPHTHALMIC COMPOSITIONS
PL199321B1 (en) 2000-07-28 2008-09-30 Alcon Inc Pharmaceutical compositions containing tobramycin and xanthan gum

Also Published As

Publication number Publication date
BR112012033052A2 (en) 2019-09-24
CA2801731A1 (en) 2011-12-29
JP2013529632A (en) 2013-07-22
CN102946855A (en) 2013-02-27
CN102946855B (en) 2016-01-06
WO2011162752A1 (en) 2011-12-29
KR20130094280A (en) 2013-08-23
AU2010356098B2 (en) 2014-08-14
EP2585037A1 (en) 2013-05-01
AU2010356098A1 (en) 2013-01-10
MX2012015051A (en) 2013-02-15
JP5728082B2 (en) 2015-06-03

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