ZA200906048B - Improved antibody profiling sensitivity through increased reporter antibody layering - Google Patents

Improved antibody profiling sensitivity through increased reporter antibody layering

Info

Publication number
ZA200906048B
ZA200906048B ZA200906048A ZA200906048A ZA200906048B ZA 200906048 B ZA200906048 B ZA 200906048B ZA 200906048 A ZA200906048 A ZA 200906048A ZA 200906048 A ZA200906048 A ZA 200906048A ZA 200906048 B ZA200906048 B ZA 200906048B
Authority
ZA
South Africa
Prior art keywords
antibody
layering
improved
increased reporter
sensitivity
Prior art date
Application number
ZA200906048A
Other languages
English (en)
Inventor
William A Apel
Vicki S Thompson
Original Assignee
Battelle Energy Alliance Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Energy Alliance Llc filed Critical Battelle Energy Alliance Llc
Publication of ZA200906048B publication Critical patent/ZA200906048B/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
ZA200906048A 2007-03-26 2009-09-01 Improved antibody profiling sensitivity through increased reporter antibody layering ZA200906048B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/691,096 US7695919B2 (en) 2001-05-10 2007-03-26 Antibody profiling sensitivity through increased reporter antibody layering

Publications (1)

Publication Number Publication Date
ZA200906048B true ZA200906048B (en) 2010-05-26

Family

ID=38369060

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200906048A ZA200906048B (en) 2007-03-26 2009-09-01 Improved antibody profiling sensitivity through increased reporter antibody layering

Country Status (13)

Country Link
US (1) US7695919B2 (xx)
EP (1) EP2126567A4 (xx)
JP (1) JP2010522885A (xx)
CN (1) CN101657723A (xx)
AU (1) AU2008231213A1 (xx)
BR (1) BRPI0809371A2 (xx)
CA (1) CA2679573A1 (xx)
CO (1) CO6231057A2 (xx)
GT (1) GT200900255A (xx)
IL (1) IL200657A0 (xx)
MX (1) MX2009009448A (xx)
WO (1) WO2008118558A2 (xx)
ZA (1) ZA200906048B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE46351E1 (en) 2001-05-10 2017-03-28 Battelle Energy Alliance, Llc Antibody profiling sensitivity through increased reporter antibody layering
US6989276B2 (en) 2001-05-10 2006-01-24 Battelle Energy Alliance, Llc Rapid classification of biological components
US20080286881A1 (en) * 2007-05-14 2008-11-20 Apel William A Compositions and methods for combining report antibodies
US20080300796A1 (en) * 2007-05-31 2008-12-04 Lassahn Gordon D Biological analysis methods, biological analysis devices, and articles of manufacture
SE533515C2 (sv) * 2008-04-16 2010-10-12 Aamic Ab Analysförfarande för samtidig analys av flera analyter
WO2010148365A2 (en) 2009-06-19 2010-12-23 The Arizona Board Of Regents, A Body Corporate Of The State Of Arizona For And On Behalf Of Arizona State University Compound arrays for sample profiling
US8969009B2 (en) * 2009-09-17 2015-03-03 Vicki S. Thompson Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
US9410965B2 (en) * 2009-09-17 2016-08-09 Battelle Energy Alliance, Llc Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
US8651158B2 (en) * 2009-11-17 2014-02-18 The United States Of America, As Represented By The Secretary Of The Navy Processing microtitre plates for covalent immobilization chemistries
US10758886B2 (en) 2015-09-14 2020-09-01 Arizona Board Of Regents On Behalf Of Arizona State University Conditioned surfaces for in situ molecular array synthesis
US11774446B2 (en) 2016-06-20 2023-10-03 Cowper Sciences Inc. Methods for diagnosis and treatment of autoimmune diseases
WO2017223116A2 (en) 2016-06-20 2017-12-28 Healthtell Inc. Methods for differential diagnosis of autoimmune diseases
AU2017357818A1 (en) 2016-11-11 2019-05-30 HealthTell, Inc. Methods for identifying candidate biomarkers
WO2019055618A1 (en) 2017-09-15 2019-03-21 Arizona Board Of Regents On Behalf Of Arizona State University METHODS OF CLASSIFYING RESPONSES TO ANTICANCER IMMUNOTHERAPY
WO2021067550A1 (en) 2019-10-02 2021-04-08 Arizona Board Of Regents On Behalf Of Arizona State University Methods and compositions for identifying neoantigens for use in treating and preventing cancer
CN113219169B (zh) * 2021-05-22 2021-12-17 北京金诺百泰生物技术有限公司 生物检测用封闭剂及其制备方法、包被板及应用该包被板的试剂盒
CN113764037B (zh) * 2021-05-28 2023-10-27 腾讯科技（深圳）有限公司 模型训练、抗体改造和结合位点预测的方法与装置

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US566558A (en) 1896-08-25 Marking instrument
US4542104A (en) 1983-04-06 1985-09-17 The Board Of Trustees Of The Leland Stanford Jr. Univ. Phycobiliprotein fluorescent conjugates
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US4880750A (en) 1987-07-09 1989-11-14 Miragen, Inc. Individual-specific antibody identification methods
ATE161096T1 (de) 1988-11-03 1997-12-15 Igen Inc Elektrochemilumineszente reaktion unter verwendung eines von einem amin abgeleiteten reduktionsmittels
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5238652A (en) * 1990-06-20 1993-08-24 Drug Screening Systems, Inc. Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques
JPH04195485A (ja) 1990-11-28 1992-07-15 Hitachi Ltd 画像情報入力装置
US5885780A (en) 1991-07-19 1999-03-23 University Of Utah Method of obtaining small conformationally rigid conopeptides
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5541113A (en) 1993-09-22 1996-07-30 Beckman Instruments, Inc. Method for detecting an analyte using an electrochemical luminescent transition metal label
EP0864082B1 (en) 1995-11-30 2003-04-02 Chromavision Medical Systems, Inc. Method for automated image analysis of biological specimens
WO1997029206A1 (en) 1996-02-12 1997-08-14 Miragen, Inc. Antibody profile linked diagnostic testing
US6103479A (en) 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US6306584B1 (en) * 1997-01-21 2001-10-23 President And Fellows Of Harvard College Electronic-property probing of biological molecules at surfaces
JP3683591B2 (ja) 1997-02-27 2005-08-17 セロミックス インコーポレイテッド 細胞に基づくスクリーニングシステム
US5858801A (en) 1997-03-13 1999-01-12 The United States Of America As Represented By The Secretary Of The Navy Patterning antibodies on a surface
US6180391B1 (en) 1998-01-28 2001-01-30 Amgen Inc. Highly efficient controlled expression of exogenous genes in e. coli
US6591196B1 (en) 2000-06-06 2003-07-08 Agilent Technologies Inc. Method and system for extracting data from surface array deposited features
US6965704B2 (en) 2000-08-22 2005-11-15 Affymetrix, Inc. System, method, and computer software product for grid alignment of multiple scanned images
US20040085443A1 (en) 2000-12-13 2004-05-06 Kallioniemi Olli P Method and system for processing regions of interest for objects comprising biological material
US7219016B2 (en) 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
US6989276B2 (en) * 2001-05-10 2006-01-24 Battelle Energy Alliance, Llc Rapid classification of biological components
AU2002315131A1 (en) 2001-06-13 2002-12-23 Elan Pharmaceuticals, Inc. Aminediols as agents for the treatment of alzheimer's disease
US6980677B2 (en) 2002-05-24 2005-12-27 Niles Scientific, Inc. Method, system, and computer code for finding spots defined in biological microarrays
US7643703B2 (en) 2003-09-03 2010-01-05 Battelle Energy Alliance, Llc Image change detection systems, methods, and articles of manufacture
US20060115429A1 (en) 2004-11-30 2006-06-01 Noubar Afeyan Biological systems analysis
AR051800A1 (es) 2004-12-15 2007-02-07 Wyeth Corp Anticuerpos a beta usados en mejorar la cognicion
EP1920073A2 (en) * 2005-07-01 2008-05-14 Dako Denmark A/S Method of simultaneously visualizing multiple biological targets

Also Published As

Publication number Publication date
CN101657723A (zh) 2010-02-24
EP2126567A2 (en) 2009-12-02
US7695919B2 (en) 2010-04-13
JP2010522885A (ja) 2010-07-08
WO2008118558A3 (en) 2008-12-18
AU2008231213A1 (en) 2008-10-02
GT200900255A (es) 2010-07-28
US20070190585A1 (en) 2007-08-16
WO2008118558A2 (en) 2008-10-02
IL200657A0 (en) 2010-05-17
BRPI0809371A2 (pt) 2014-09-16
CO6231057A2 (es) 2010-12-20
MX2009009448A (es) 2009-09-16
CA2679573A1 (en) 2008-10-02
EP2126567A4 (en) 2010-04-28

Similar Documents

Publication Publication Date Title
IL200657A0 (en) Improved antibody profiling sensitivity through increased reporter antibody layering
GB2454359B (en) Seismic sensing
DK2059534T3 (da) Gensplejsede anti-il-23p19-antistoffer
ZA201102119B (en) Improved antibody libraies
BRPI0906877A2 (pt) Anticorpos anti-trkb aperfeiçoados
EP2241578A4 (en) ANTI-CLDN6 ANTIBODIES
HK1136970A1 (en) Penta-specific antibody
EP2138576A4 (en) ANTI-CLAUDIN-4 ANTIBODY
BRPI0921773A2 (pt) indicador de carga
BRPI0915491A2 (pt) sensor de imunoensaio
DE602008004276D1 (de) Luftkanone
ATE536091T1 (de) Binderbodensensor
EP2172483A4 (en) ANTI-MUC17 ANTIBODY
EP2179306A4 (en) DETERMINATION OF FORMATION PROPERTIES
BRPI0817427A2 (pt) Anticorpo anti-bst2
DE602008002287D1 (de) Aufzeichnungsgerät
BRPI0909633A2 (pt) anticorpos anti-tyrp1
BRPI0912769A2 (pt) anticorpos anti-pirb
DE602008005825D1 (de) Luftdruckwaffe
DE602008002037D1 (de) Aufzeichnungsgerät
GB0911770D0 (en) Antibody
FI20086029A0 (fi) Mittausjärjestely
TWM298710U (en) Improved proportion measurement structure
GB0702892D0 (en) Sensitivity test
SE0700306L (sv) Harmonianalys