ZA200903334B - Substituted diazepan compounds as orexin receptor antagonists - Google Patents

Substituted diazepan compounds as orexin receptor antagonists

Info

Publication number
ZA200903334B
ZA200903334B ZA200903334A ZA200903334A ZA200903334B ZA 200903334 B ZA200903334 B ZA 200903334B ZA 200903334 A ZA200903334 A ZA 200903334A ZA 200903334 A ZA200903334 A ZA 200903334A ZA 200903334 B ZA200903334 B ZA 200903334B
Authority
ZA
South Africa
Prior art keywords
receptor antagonists
orexin receptor
diazepan compounds
substituted diazepan
substituted
Prior art date
Application number
ZA200903334A
Inventor
Jeffrey M Bergman
Michael J Breslin
Paul J Coleman
Christopher D Cox
Swati P Mercer
Anthony J Roecker
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA200903334B publication Critical patent/ZA200903334B/en

Links

ZA200903334A 2006-12-01 2009-05-14 Substituted diazepan compounds as orexin receptor antagonists ZA200903334B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87239306P 2006-12-01 2006-12-01

Publications (1)

Publication Number Publication Date
ZA200903334B true ZA200903334B (en) 2010-04-28

Family

ID=41522310

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200903334A ZA200903334B (en) 2006-12-01 2009-05-14 Substituted diazepan compounds as orexin receptor antagonists

Country Status (4)

Country Link
CN (1) CN101627028B (en)
HN (1) HN2009001067A (en)
UA (2) UA100974C2 (en)
ZA (1) ZA200903334B (en)

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WO2014072961A2 (en) * 2012-11-12 2014-05-15 Dr. Reddy's Laboratories Limited Polymorphic forms of suvoroxant
CN103012293A (en) * 2012-12-13 2013-04-03 同济大学 Synthetic method for anti-sleeplessness medicine MK-4305 intermediate
CN103923068B (en) * 2014-02-13 2016-09-07 武汉珈瑜科技有限公司 For compound preparing suvorexant and preparation method thereof
WO2015180060A1 (en) * 2014-05-28 2015-12-03 杭州普晒医药科技有限公司 Salt of diazacycloheptane compound and crystal form and amorphous substance thereof
EP3177616B1 (en) * 2014-08-04 2021-02-24 Sandoz AG Novel routes of synthesis for the preparation of suvorexant
CN105461699B (en) * 2014-09-25 2019-07-09 广东东阳光药业有限公司 Substituted heterocyclic compound and its application method and purposes
CN104327061A (en) * 2014-10-19 2015-02-04 湖南华腾制药有限公司 Preparation method of bromobenzo[d]oxazole derivative
CN104649983B (en) * 2014-12-23 2018-01-23 广东东阳光药业有限公司 A kind of sour preparation method
CN106349228B (en) * 2015-07-17 2019-07-09 广东东阳光药业有限公司 Substituted quianzolinones and its preparation method and application
US10370380B2 (en) * 2015-11-23 2019-08-06 Sunshine Lake Pharma Co., Ltd. Octahydropyrrolo[3,4-c]pyrrole derivatives and uses thereof
CN106916149A (en) * 2015-12-25 2017-07-04 上海奥博生物医药技术有限公司 A kind of method for preparing Su Woleisheng
CN107021964A (en) * 2016-02-01 2017-08-08 广东东阳光药业有限公司 7-naphthyridine derivatives and application thereof
CN105949203B (en) * 2016-05-24 2018-07-13 广东东阳光药业有限公司 Octahydro pyrrolo- [3,4-c] azole derivatives and its application method and purposes
CN106866632A (en) * 2017-01-19 2017-06-20 成都美域高制药有限公司 A kind of method for preparing Suvorexant intermediates and the like
CN109942563A (en) * 2017-12-21 2019-06-28 上海医药工业研究院 A kind of preparation method of Su Woleisheng midbody compound
WO2020247445A1 (en) * 2019-06-04 2020-12-10 Hager Biosciences, Llc Imidazolo derivatives, compositions and methods as orexin antagonists
CN111943945B (en) * 2020-09-03 2022-07-12 上海应用技术大学 Suvorexant intermediate and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS536156B2 (en) * 1972-10-30 1978-03-04
EP0794178A4 (en) * 1994-11-25 1998-02-25 Nippon Chemiphar Co Quinazoline derivative
KR100774621B1 (en) * 2003-09-09 2007-11-14 에프. 호프만-라 로슈 아게 1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses

Also Published As

Publication number Publication date
UA106873C2 (en) 2014-10-27
UA100974C2 (en) 2013-02-25
HN2009001067A (en) 2011-05-11
CN101627028A (en) 2010-01-13
CN101627028B (en) 2013-03-27

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