ZA200808647B - Glycosylated antibodies - Google Patents

Glycosylated antibodies

Info

Publication number
ZA200808647B
ZA200808647B ZA200808647A ZA200808647A ZA200808647B ZA 200808647 B ZA200808647 B ZA 200808647B ZA 200808647 A ZA200808647 A ZA 200808647A ZA 200808647 A ZA200808647 A ZA 200808647A ZA 200808647 B ZA200808647 B ZA 200808647B
Authority
ZA
South Africa
Prior art keywords
glycosylated antibodies
glycosylated
antibodies
Prior art date
Application number
ZA200808647A
Inventor
Silke Hansen
Klause-Peter Kuenkele
Dietmar Reusch
Ralf Schumacher
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA200808647B publication Critical patent/ZA200808647B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/72—Increased effector function due to an Fc-modification
ZA200808647A 2006-04-11 2008-10-09 Glycosylated antibodies ZA200808647B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06007565 2006-04-11

Publications (1)

Publication Number Publication Date
ZA200808647B true ZA200808647B (en) 2009-12-30

Family

ID=36452141

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200808647A ZA200808647B (en) 2006-04-11 2008-10-09 Glycosylated antibodies

Country Status (2)

Country Link
CN (1) CN101460522B (en)
ZA (1) ZA200808647B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120196310A1 (en) * 2009-10-02 2012-08-02 Christiane Jaeger A-fucosylation detection in antibodies
BR112014003110A2 (en) * 2011-08-10 2018-10-09 Lab Francais Du Fractionnement composition, method for producing a highly galactosylated population of antibodies, mammary gland epithelial cells and tramsgenic non-human mammal
WO2014140927A2 (en) 2013-02-13 2014-09-18 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
ES2755181T3 (en) 2013-02-13 2020-04-21 Lab Francais Du Fractionnement Highly galactosylated anti-TNF-alpha antibodies and uses thereof
CN110241134A (en) * 2018-03-08 2019-09-17 中国科学院上海高等研究院 A method of transformation CHO-lec2 cell improves galactose content in antibody sugar chain
CN110241133A (en) * 2018-03-08 2019-09-17 中国科学院上海高等研究院 A method of transformation CHO-K1 cell improves galactose content in antibody sugar chain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR046071A1 (en) * 2003-07-10 2005-11-23 Hoffmann La Roche ANTIBODIES AGAINST RECEIVER I OF THE INSULINAL TYPE GROWTH FACTOR AND THE USES OF THE SAME
AR045614A1 (en) * 2003-09-10 2005-11-02 Hoffmann La Roche ANTIBODIES AGAINST THE RECEIVER OF INTERLEUQUINA- 1 AND USES OF THE SAME

Also Published As

Publication number Publication date
CN101460522A (en) 2009-06-17
CN101460522B (en) 2014-07-23

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