ZA200803580B - N-Benzyl Substituted Pyridyl Porphyrin Compounds and methods of use thereof - Google Patents
N-Benzyl Substituted Pyridyl Porphyrin Compounds and methods of use thereofInfo
- Publication number
- ZA200803580B ZA200803580B ZA200803580A ZA200803580A ZA200803580B ZA 200803580 B ZA200803580 B ZA 200803580B ZA 200803580 A ZA200803580 A ZA 200803580A ZA 200803580 A ZA200803580 A ZA 200803580A ZA 200803580 B ZA200803580 B ZA 200803580B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- substituted pyridyl
- benzyl substituted
- porphyrin compounds
- pyridyl porphyrin
- Prior art date
Links
- -1 Pyridyl Porphyrin Compounds Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/16—Emollients or protectives, e.g. against radiation
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Obesity (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72138805P | 2005-09-28 | 2005-09-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200803580B true ZA200803580B (en) | 2009-01-28 |
Family
ID=37900440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200803580A ZA200803580B (en) | 2005-09-28 | 2008-04-23 | N-Benzyl Substituted Pyridyl Porphyrin Compounds and methods of use thereof |
Country Status (7)
Country | Link |
---|---|
US (2) | US7642250B2 (ja) |
EP (1) | EP1928467A4 (ja) |
JP (1) | JP2009510083A (ja) |
AU (1) | AU2006294655A1 (ja) |
CA (1) | CA2622988A1 (ja) |
WO (1) | WO2007038630A2 (ja) |
ZA (1) | ZA200803580B (ja) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA06011244A (es) * | 2004-03-29 | 2007-04-13 | Inotek Pharmaceuticals Corp | Compuestos de porfirina sustituida por piridilo, y metodos de uso de los mismos. |
US20110111007A1 (en) * | 2005-04-29 | 2011-05-12 | Mcginnis James F | Inhibition of retinal cell degeneration or neovascularization by cerium oxide nanoparticles |
US7959949B2 (en) | 2006-04-27 | 2011-06-14 | University Of Central Florida Research Foundation, Inc. | Functionalized nanoceria composition for ophthalmic treatment |
US9119391B1 (en) | 2007-07-16 | 2015-09-01 | University Of Central Florida Research Foundation, Inc. | Polymer coated ceria nanoparticles for selective cytoprotection |
US20090257999A1 (en) * | 2007-12-31 | 2009-10-15 | Inotek Pharmaceuticals Corporation | Method of preventing contrast-induced nephropathy |
US8916199B1 (en) | 2008-04-25 | 2014-12-23 | University of Central Florida Research Foundation, Ind. | Inhibition of angiogenesis associated with ovarian cancer by nanoparticles of cerium oxide |
AU2009240470B8 (en) * | 2008-04-25 | 2015-02-05 | The Board Of Regents Of The University Of Oklahoma | Inhibition of neovascularization by cerium oxide nanoparticles |
US9127202B1 (en) | 2008-07-18 | 2015-09-08 | University Of Central Florida Research Foundation, Inc. | Biocompatible nano rare earth oxide upconverters for imaging and therapeutics |
US8883519B1 (en) | 2009-03-17 | 2014-11-11 | University Of Central Florida Research Foundation, Inc. | Oxidase activity of polymeric coated cerium oxide nanoparticles |
US20120065181A1 (en) * | 2009-05-26 | 2012-03-15 | Warner David S | Method of providing neuroprotection using substituted porphyrins |
US9585840B1 (en) | 2009-07-10 | 2017-03-07 | University Of Central Florida Research Foundation, Inc. | Redox active cerium oxide nanoparticles and associated methods |
US8795731B1 (en) | 2009-10-12 | 2014-08-05 | University Of Central Florida Research Foundation, Inc. | Cerium oxide nanoparticle-based device for the detection of reactive oxygen species and monitoring of chronic inflammation |
US8877207B2 (en) | 2010-09-17 | 2014-11-04 | University Of Central Florida Research Foundation, Inc. | Nanoparticles of cerium oxide targeted to an amyloid-beta antigen of Alzheimer's disease and associated methods |
US9274060B1 (en) | 2011-01-13 | 2016-03-01 | Mocon, Inc. | Methods for transmembrane measurement of oxygen concentration and monitoring changes in oxygen concentration within a space enclosed by a membrane employing a photoluminescent transmembrane oxygen probe |
US8907081B2 (en) | 2011-05-27 | 2014-12-09 | Sharp Laboratories Of America, Inc. | Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells |
US8951539B1 (en) | 2011-06-07 | 2015-02-10 | University Of Central Florida Research Foundation, Inc. | Methods of promoting angiogenesis using cerium oxide nanoparticles |
US9161950B2 (en) | 2011-09-21 | 2015-10-20 | University Of Central Florida Foundation, Inc. | Neuronal protection by cerium oxide nanoparticles |
CN102408452B (zh) * | 2011-12-13 | 2014-09-03 | 中山大学 | 四吡啶基卟啉桥联十字形四核铂配合物及其制备方法和抗肿瘤活性 |
WO2013151698A1 (en) | 2012-04-04 | 2013-10-10 | Duke University | Methods for using cerium oxide nanoparticles to mitigate or protect against radiation injury |
WO2013153873A1 (ja) * | 2012-04-09 | 2013-10-17 | 東洋合成工業株式会社 | 感光性化合物、感光性樹脂及び感光性組成物 |
US8658429B1 (en) | 2012-08-06 | 2014-02-25 | Mocon, Inc. | Photoluminescent oxygen probe tack |
US9463437B2 (en) | 2013-02-14 | 2016-10-11 | University Of Central Florida Research Foundation, Inc. | Methods for scavenging nitric oxide using cerium oxide nanoparticles |
US9733187B2 (en) * | 2015-03-06 | 2017-08-15 | King Saud University | Method of detecting bladder cancer by optical analysis of bodily fluids |
WO2022047196A1 (en) * | 2020-08-28 | 2022-03-03 | Nisibis, Llc-S | Pten inhibitors for treatment and prevention of bone marrow loss |
CN115792075B (zh) * | 2021-09-10 | 2023-11-03 | 江苏瑞科生物技术股份有限公司 | 4′-单磷酰脂质a类化合物的检测方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040223A1 (en) | 1995-06-07 | 1996-12-19 | Duke University | Oxidant scavengers |
EP0988037A1 (en) | 1997-02-05 | 2000-03-29 | Board Of Regents, The University Of Texas System | Porphyrin compounds as telomerase inhibitors |
DE69813898T2 (de) * | 1997-11-03 | 2004-03-11 | Duke University | Substituierte porphyrinen |
IL126953A0 (en) * | 1998-11-08 | 1999-09-22 | Yeda Res & Dev | Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives |
US6448239B1 (en) | 1999-06-03 | 2002-09-10 | Trustees Of Princeton University | Peroxynitrite decomposition catalysts and methods of use thereof |
US6573258B2 (en) * | 2000-09-27 | 2003-06-03 | Frontier Scientific, Inc. | Photodynamic porphyrin antimicrobial agents |
WO2002098431A1 (en) * | 2001-06-01 | 2002-12-12 | National Jewish Medical And Research Center | Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance |
CA2488500A1 (en) * | 2002-06-07 | 2003-12-18 | Duke University | Substituted porphyrins |
US7807825B2 (en) * | 2004-02-09 | 2010-10-05 | Duke University | Substituted porphyrins |
MXPA06011244A (es) * | 2004-03-29 | 2007-04-13 | Inotek Pharmaceuticals Corp | Compuestos de porfirina sustituida por piridilo, y metodos de uso de los mismos. |
WO2008045358A1 (en) | 2006-10-06 | 2008-04-17 | Trustees Of Princeton | Porphyrin catalysts and methods of use thereof |
-
2006
- 2006-09-26 WO PCT/US2006/037742 patent/WO2007038630A2/en active Application Filing
- 2006-09-26 CA CA002622988A patent/CA2622988A1/en not_active Abandoned
- 2006-09-26 JP JP2008533585A patent/JP2009510083A/ja not_active Withdrawn
- 2006-09-26 US US11/528,082 patent/US7642250B2/en not_active Expired - Fee Related
- 2006-09-26 AU AU2006294655A patent/AU2006294655A1/en not_active Abandoned
- 2006-09-26 EP EP06815616A patent/EP1928467A4/en not_active Withdrawn
-
2008
- 2008-04-23 ZA ZA200803580A patent/ZA200803580B/xx unknown
-
2009
- 2009-11-20 US US12/622,809 patent/US20100113386A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20100113386A1 (en) | 2010-05-06 |
US7642250B2 (en) | 2010-01-05 |
EP1928467A4 (en) | 2009-11-04 |
US20070072825A1 (en) | 2007-03-29 |
CA2622988A1 (en) | 2007-04-05 |
JP2009510083A (ja) | 2009-03-12 |
WO2007038630A3 (en) | 2007-10-25 |
WO2007038630A2 (en) | 2007-04-05 |
EP1928467A2 (en) | 2008-06-11 |
AU2006294655A1 (en) | 2007-04-05 |
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