ZA200702321B - Novel gene disruptions, compositions and methods relating thereto - Google Patents
Novel gene disruptions, compositions and methods relating theretoInfo
- Publication number
- ZA200702321B ZA200702321B ZA200702321A ZA200702321A ZA200702321B ZA 200702321 B ZA200702321 B ZA 200702321B ZA 200702321 A ZA200702321 A ZA 200702321A ZA 200702321 A ZA200702321 A ZA 200702321A ZA 200702321 B ZA200702321 B ZA 200702321B
- Authority
- ZA
- South Africa
- Prior art keywords
- compositions
- methods relating
- novel gene
- gene disruptions
- disruptions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Environmental Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60432304P | 2004-08-25 | 2004-08-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200702321B true ZA200702321B (en) | 2009-09-30 |
Family
ID=35677379
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200702321A ZA200702321B (en) | 2004-08-25 | 2005-08-23 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802563A ZA200802563B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802556A ZA200802556B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802560A ZA200802560B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802557A ZA200802557B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802558A ZA200802558B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802559A ZA200802559B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802561A ZA200802561B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802562A ZA200802562B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
Family Applications After (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200802563A ZA200802563B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802556A ZA200802556B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802560A ZA200802560B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802557A ZA200802557B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802558A ZA200802558B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802559A ZA200802559B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802561A ZA200802561B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
ZA200802562A ZA200802562B (en) | 2004-08-25 | 2008-03-19 | Novel gene disruptions, compositions and methods relating thereto |
Country Status (7)
Country | Link |
---|---|
US (2) | US7956237B2 (fr) |
EP (1) | EP1781824A2 (fr) |
JP (1) | JP2008510488A (fr) |
AU (1) | AU2005280266A1 (fr) |
CA (1) | CA2577102A1 (fr) |
WO (1) | WO2006026222A2 (fr) |
ZA (9) | ZA200702321B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7981420B2 (en) | 2000-12-22 | 2011-07-19 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Therapeutic use of antibodies directed against repulsive guidance molecule (RGM) |
JP2009510002A (ja) | 2005-09-30 | 2009-03-12 | アボット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 反発誘導分子(rgm)タンパク質ファミリーのタンパク質の結合ドメイン、及びその機能的断片、及びそれらの使用 |
JP2009544324A (ja) * | 2006-07-28 | 2009-12-17 | ジェネンテック・インコーポレーテッド | 遺伝子破壊、それに関連する組成物および方法 |
WO2009037295A1 (fr) * | 2007-09-18 | 2009-03-26 | Commissariat A L'energie Atomique | Procédé pour tester une sensibilité au psoriasis |
CA2715628A1 (fr) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systemes et procedes pour traiter, transmettre et afficher des donnees de detecteur |
US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
MX2012006560A (es) | 2009-12-08 | 2012-10-05 | Abbott Gmbh & Co Kg | Anticuerpos monoclonales contra la proteina rgm a para utilizarse en el tratamiento de degeneracion de capa de fibra de nervio retinal. |
EP2750662A4 (fr) | 2011-08-31 | 2015-06-24 | Univ Georgia | Nanoparticules ciblant l'apoptose |
PL2807192T3 (pl) | 2012-01-27 | 2019-02-28 | Abbvie Deutschland | Kompozycja oraz sposób diagnostyki i leczenia chorób związanych ze zwyrodnieniem neurytów |
ES2669561T3 (es) | 2012-02-17 | 2018-05-28 | University Of Georgia Research Foundation, Inc. | Nanopartículas para el transporte mitocondrial de agentes |
WO2015138992A1 (fr) | 2014-03-14 | 2015-09-17 | University Of Georgia Research Foundation, Inc. | Administration de 3-bromopyruvate dans les mitochondries |
CN111778284B (zh) * | 2020-06-24 | 2023-09-22 | 西安医学院 | 通过ctrp6介导的动脉粥样化动物模型及其建立方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000053753A2 (fr) | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Activation ou inhibition de l'angiogenese et de la cardiovascularisation |
US6057435A (en) * | 1997-09-19 | 2000-05-02 | Genentech, Inc. | Tie ligand homologues |
US7378507B2 (en) * | 1997-09-18 | 2008-05-27 | Genentech, Inc. | PRO217 polypeptides |
CA2372511C (fr) * | 1999-06-15 | 2011-11-22 | Genentech, Inc. | Polypeptides secretes et transmembranaires et acides nucleiques les codant |
US7390879B2 (en) * | 1999-06-15 | 2008-06-24 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO2002040662A2 (fr) * | 2000-11-15 | 2002-05-23 | Deltagen, Inc. | Souris transgenique contenant des disruptions geniques ciblees |
ZA200801231B (en) | 2003-12-16 | 2009-05-27 | Genentech Inc | Novel gene disruptions, compositions and methods relating thereto |
ZA200606461B (en) | 2004-02-12 | 2008-02-27 | Lexicon Pharmaceuticals Inc | Gene disruptions, compositions and methods relating thereto |
ZA200608527B (en) * | 2004-05-12 | 2007-12-27 | Genentech Inc | Novel gene disruptions, compositions and methods relating thereto |
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2005
- 2005-08-23 US US11/572,702 patent/US7956237B2/en not_active Expired - Fee Related
- 2005-08-23 JP JP2007530006A patent/JP2008510488A/ja active Pending
- 2005-08-23 AU AU2005280266A patent/AU2005280266A1/en not_active Abandoned
- 2005-08-23 CA CA002577102A patent/CA2577102A1/fr not_active Abandoned
- 2005-08-23 WO PCT/US2005/029782 patent/WO2006026222A2/fr active Application Filing
- 2005-08-23 EP EP05793413A patent/EP1781824A2/fr not_active Withdrawn
- 2005-08-23 ZA ZA200702321A patent/ZA200702321B/xx unknown
-
2008
- 2008-03-19 ZA ZA200802563A patent/ZA200802563B/en unknown
- 2008-03-19 ZA ZA200802556A patent/ZA200802556B/en unknown
- 2008-03-19 ZA ZA200802560A patent/ZA200802560B/en unknown
- 2008-03-19 ZA ZA200802557A patent/ZA200802557B/en unknown
- 2008-03-19 ZA ZA200802558A patent/ZA200802558B/xx unknown
- 2008-03-19 ZA ZA200802559A patent/ZA200802559B/en unknown
- 2008-03-19 ZA ZA200802561A patent/ZA200802561B/en unknown
- 2008-03-19 ZA ZA200802562A patent/ZA200802562B/xx unknown
-
2010
- 2010-11-12 US US12/945,589 patent/US20110061114A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2577102A1 (fr) | 2006-03-09 |
ZA200802562B (en) | 2010-02-24 |
ZA200802558B (en) | 2010-01-27 |
US20110061114A1 (en) | 2011-03-10 |
US20080160034A1 (en) | 2008-07-03 |
ZA200802563B (en) | 2010-02-24 |
WO2006026222A3 (fr) | 2006-06-01 |
ZA200802560B (en) | 2009-05-27 |
EP1781824A2 (fr) | 2007-05-09 |
ZA200802557B (en) | 2010-01-27 |
WO2006026222A2 (fr) | 2006-03-09 |
ZA200802561B (en) | 2010-02-24 |
ZA200802556B (en) | 2010-02-24 |
AU2005280266A1 (en) | 2006-03-09 |
US7956237B2 (en) | 2011-06-07 |
JP2008510488A (ja) | 2008-04-10 |
ZA200802559B (en) | 2009-05-27 |
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