ZA200700670B - Mixed solvate of olanzapine, method for preparing it and method for preparing form I of olanzapine therefrom - Google Patents

Mixed solvate of olanzapine, method for preparing it and method for preparing form I of olanzapine therefrom

Info

Publication number
ZA200700670B
ZA200700670B ZA200700670A ZA200700670A ZA200700670B ZA 200700670 B ZA200700670 B ZA 200700670B ZA 200700670 A ZA200700670 A ZA 200700670A ZA 200700670 A ZA200700670 A ZA 200700670A ZA 200700670 B ZA200700670 B ZA 200700670B
Authority
ZA
South Africa
Prior art keywords
olanzapine
preparing
therefrom
mixed solvate
preparing form
Prior art date
Application number
ZA200700670A
Other languages
English (en)
Inventor
Dalmases Barjoan Pere
Bessa Bellmunt Jordi
Original Assignee
Inke Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inke Sa filed Critical Inke Sa
Publication of ZA200700670B publication Critical patent/ZA200700670B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA200700670A 2004-07-27 2005-07-07 Mixed solvate of olanzapine, method for preparing it and method for preparing form I of olanzapine therefrom ZA200700670B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200401850A ES2253091B1 (es) 2004-07-27 2004-07-27 Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.

Publications (1)

Publication Number Publication Date
ZA200700670B true ZA200700670B (en) 2008-08-27

Family

ID=35064845

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200700670A ZA200700670B (en) 2004-07-27 2005-07-07 Mixed solvate of olanzapine, method for preparing it and method for preparing form I of olanzapine therefrom

Country Status (13)

Country Link
US (1) US7759484B2 (xx)
EP (1) EP1773841B1 (xx)
JP (1) JP2008508254A (xx)
KR (1) KR20070063496A (xx)
AR (1) AR050359A1 (xx)
AT (1) ATE380191T1 (xx)
DE (1) DE602005003678T2 (xx)
ES (2) ES2253091B1 (xx)
PL (1) PL1773841T3 (xx)
PT (1) PT1773841E (xx)
TW (1) TWI295993B (xx)
WO (1) WO2006013435A1 (xx)
ZA (1) ZA200700670B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003300324A1 (en) 2002-12-24 2004-07-22 Teva Pharmaceutical Industries Ltd. Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
EP2264016B1 (en) * 2004-07-14 2013-05-01 Jubilant Organosys Limited A process for producing pure form form of 2-Methyl-4-(4-Methyl-1-Piperazinyl)-10h-thieno[2,3-B][1,5] benzodiazepine
ES2292333B1 (es) * 2004-07-27 2008-12-16 Inke, S.A. Mejoras en el objeto de la patente principal n. 200401850, por "solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo".
ES2279715B1 (es) 2005-12-26 2008-06-01 Laboratorios Lesvi, S.L. Formulacion oral de olanzapina.
WO2007077134A1 (en) * 2006-01-05 2007-07-12 Inke, S.A. Method for preparing a mixed solvate of 0lanzapine
CN102532158A (zh) * 2010-12-17 2012-07-04 北大方正集团有限公司 一种合成奥氮平的方法
JP6042153B2 (ja) * 2012-09-26 2016-12-14 株式会社トクヤマ オランザピンの製造方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
US5637584A (en) 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
ZA978515B (en) 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
CZ300725B6 (cs) * 1997-09-30 2009-07-29 Eli Lilly And Company 2-Methylthienbenzodiazepinová formulace
CA2344873A1 (en) * 1998-09-30 2000-04-06 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
IL154688A0 (en) 2000-08-31 2003-09-17 Reddys Lab Ltd Dr Hydrates of olanzapine and processes for the preparation thereof
AU2002367119A1 (en) 2001-12-24 2003-07-15 Sun Pharmaceutical Industries Limited Crystalline form I of 2-methyl-4-(4-methyl-1-piperazinyl) 10H thieno [2,3-b][1,5]benzodiazepine
PL196814B1 (pl) * 2002-05-17 2008-02-29 Inst Farmaceutyczny Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty
SI1513846T1 (sl) 2002-05-31 2011-11-30 Sandoz Ag Postopek za pripravo olanzapina form I
SI21270A (sl) * 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
AU2003300324A1 (en) * 2002-12-24 2004-07-22 Teva Pharmaceutical Industries Ltd. Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms

Also Published As

Publication number Publication date
ATE380191T1 (de) 2007-12-15
WO2006013435A1 (en) 2006-02-09
EP1773841A1 (en) 2007-04-18
TW200613284A (en) 2006-05-01
AR050359A1 (es) 2006-10-18
ES2253091A1 (es) 2006-05-16
PL1773841T3 (pl) 2008-04-30
ES2253091B1 (es) 2007-02-01
JP2008508254A (ja) 2008-03-21
DE602005003678T2 (de) 2008-11-20
US20080280884A1 (en) 2008-11-13
ES2299049T3 (es) 2008-05-16
KR20070063496A (ko) 2007-06-19
DE602005003678D1 (de) 2008-01-17
EP1773841B1 (en) 2007-12-05
PT1773841E (pt) 2008-02-20
TWI295993B (en) 2008-04-21
US7759484B2 (en) 2010-07-20

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