ZA200604013B - Novel carboxamides for use as xa inhibitors - Google Patents

Novel carboxamides for use as xa inhibitors

Info

Publication number
ZA200604013B
ZA200604013B ZA200604013A ZA200604013A ZA200604013B ZA 200604013 B ZA200604013 B ZA 200604013B ZA 200604013 A ZA200604013 A ZA 200604013A ZA 200604013 A ZA200604013 A ZA 200604013A ZA 200604013 B ZA200604013 B ZA 200604013B
Authority
ZA
South Africa
Prior art keywords
inhibitors
novel carboxamides
carboxamides
novel
Prior art date
Application number
ZA200604013A
Inventor
Gerlach Kai
Priepke Henning
Schuler-Metz Annete
Nar Herbert
Hauel Norbert
Pfau Roland
Wienen Wolfgang
Dahmann Georg
Handschuh Sandra Ruth
Kauffmann-Hefner Iris
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA200604013B publication Critical patent/ZA200604013B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200604013A 2004-02-28 2006-05-18 Novel carboxamides for use as xa inhibitors ZA200604013B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004009835A DE102004009835A1 (en) 2004-02-28 2004-02-28 New 4-heterocyclyl-benzamide derivatives, useful as antithrombotic agents for treating or preventing e.g. deep vein thrombosis or reocclusion after angioplasty, are inhibitors of factor Xa and other serine proteases

Publications (1)

Publication Number Publication Date
ZA200604013B true ZA200604013B (en) 2007-08-29

Family

ID=34853838

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200604013A ZA200604013B (en) 2004-02-28 2006-05-18 Novel carboxamides for use as xa inhibitors

Country Status (5)

Country Link
CN (1) CN101103022B (en)
DE (1) DE102004009835A1 (en)
ES (1) ES2371920T3 (en)
UA (1) UA86616C2 (en)
ZA (1) ZA200604013B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006031715A2 (en) * 2004-09-10 2006-03-23 Janssen Pharmaceutica N.V. Novel imidazolidin-2-one derivatives as selective androgen receptor modulators (sarms)
GB201909190D0 (en) * 2019-06-26 2019-08-07 Ucb Biopharma Sprl Therapeutic agents
CN112574181A (en) * 2019-09-30 2021-03-30 天津药业研究院股份有限公司 Preparation method and application of suvorexant intermediate
CN112354005B (en) * 2020-11-11 2021-07-27 问兰药业(苏州)有限公司 Dressing for promoting healing of burn and scald wound surfaces and preparation method thereof

Also Published As

Publication number Publication date
CN101103022A (en) 2008-01-09
DE102004009835A1 (en) 2005-09-15
UA86616C2 (en) 2009-05-12
CN101103022B (en) 2012-06-27
ES2371920T3 (en) 2012-01-11

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