ZA200505321B - Topical stabilized prostaglandin E compound dosage forms - Google Patents
Topical stabilized prostaglandin E compound dosage forms Download PDFInfo
- Publication number
- ZA200505321B ZA200505321B ZA200505321A ZA200505321A ZA200505321B ZA 200505321 B ZA200505321 B ZA 200505321B ZA 200505321 A ZA200505321 A ZA 200505321A ZA 200505321 A ZA200505321 A ZA 200505321A ZA 200505321 B ZA200505321 B ZA 200505321B
- Authority
- ZA
- South Africa
- Prior art keywords
- dosage form
- prostaglandin
- compound
- group
- accordance
- Prior art date
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- -1 prostaglandin E compound Chemical class 0.000 title claims abstract description 48
- 239000002552 dosage form Substances 0.000 title claims description 28
- 230000000699 topical effect Effects 0.000 title claims description 22
- 150000001875 compounds Chemical class 0.000 claims abstract description 56
- 239000000203 mixture Substances 0.000 claims abstract description 46
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical group CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 claims abstract description 30
- 239000007909 solid dosage form Substances 0.000 claims abstract description 18
- 239000003961 penetration enhancing agent Substances 0.000 claims abstract description 17
- 239000004067 bulking agent Substances 0.000 claims abstract description 7
- 150000003839 salts Chemical class 0.000 claims description 11
- HSMMSDWNEJLVRY-INIZCTEOSA-N dodecyl (2s)-2-(dimethylamino)propanoate Chemical group CCCCCCCCCCCCOC(=O)[C@H](C)N(C)C HSMMSDWNEJLVRY-INIZCTEOSA-N 0.000 claims description 7
- 239000003125 aqueous solvent Substances 0.000 claims description 4
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- IPWWTXFQEUNUNX-UHFFFAOYSA-N dodecyl 2-(dimethylamino)propanoate;hydrochloride Chemical compound Cl.CCCCCCCCCCCCOC(=O)C(C)N(C)C IPWWTXFQEUNUNX-UHFFFAOYSA-N 0.000 claims 2
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/336,481 US6841574B2 (en) | 2003-01-03 | 2003-01-03 | Topical stabilized prostaglandin E compound dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200505321B true ZA200505321B (en) | 2006-04-26 |
Family
ID=32681022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200505321A ZA200505321B (en) | 2003-01-03 | 2005-06-30 | Topical stabilized prostaglandin E compound dosage forms |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6841574B2 (fr) |
| EP (1) | EP1585483B1 (fr) |
| JP (2) | JP2006514068A (fr) |
| KR (2) | KR20050098853A (fr) |
| CN (1) | CN100574763C (fr) |
| AT (1) | ATE468098T1 (fr) |
| AU (1) | AU2003300113B2 (fr) |
| BR (1) | BR0317924A (fr) |
| CA (1) | CA2512015C (fr) |
| DE (1) | DE60332656D1 (fr) |
| DK (1) | DK1585483T3 (fr) |
| ES (1) | ES2343246T3 (fr) |
| HK (1) | HK1090293A1 (fr) |
| IL (1) | IL169425A (fr) |
| PT (1) | PT1585483E (fr) |
| WO (1) | WO2004062632A1 (fr) |
| ZA (1) | ZA200505321B (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050004226A1 (en) * | 1998-12-10 | 2005-01-06 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
| JP4667369B2 (ja) | 2003-03-21 | 2011-04-13 | ネックスメド ホールディングス インコーポレイテッド | 早漏を治療するための組成物および方法 |
| US20050113274A1 (en) * | 2003-11-22 | 2005-05-26 | Nadir Buyuktimkin | Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| CA2610465A1 (fr) * | 2005-06-03 | 2006-12-14 | Duramed Pharmaceuticals, Inc. | Compositions pharmaceutiques comprenant des agonistes des recepteurs prostanoides et procedes de fabrication et d'utilisation de celles-ci |
| ITMI20051417A1 (it) * | 2005-07-22 | 2007-01-23 | Mipharm S P A | Formulazione topica in forma di gel contenente come ingredienti attivi ciclovit e lidocaina |
| EP1971312A1 (fr) * | 2005-12-06 | 2008-09-24 | MonoSol Rx LLC | Compositions de films topiques pour la liberation d actifs |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| US7560489B2 (en) * | 2006-10-11 | 2009-07-14 | Nexmed Holdings, Inc. | Stabilized prostaglandin E composition |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| ES2921527T3 (es) | 2009-06-03 | 2022-08-29 | Forsight Vision5 Inc | Administración de fármaco en segmento anterior |
| US8939948B2 (en) | 2010-06-01 | 2015-01-27 | Forsight Vision5, Inc. | Ocular insert apparatus and methods |
| US8940794B2 (en) | 2011-04-07 | 2015-01-27 | Nexmed Holdings, Inc. | Methods and compositions for treating Raynaud's disease |
| CN104884006B (zh) | 2012-10-26 | 2017-12-15 | 弗赛特影像5股份有限公司 | 用于持续释放药物到眼睛的眼科系统 |
| US8900625B2 (en) | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
| EP3283004A4 (fr) | 2015-04-13 | 2018-12-05 | Forsight Vision5, Inc. | Composition d'insert oculaire d'agent pharmaceutiquement actif cristallin ou semi-cristallin |
| WO2019142015A1 (fr) * | 2018-01-18 | 2019-07-25 | Caicedo Pinto, David Felipe | Composition pharmaceutique d'administration transdermique par voie urétrale en gouttes pour le traitement de la dysfonction érectile |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883576A (en) * | 1971-02-02 | 1975-05-13 | Upjohn Co | Prostaglandin E{HD 3 {B analogs |
| US3826823A (en) * | 1972-09-25 | 1974-07-30 | Syntex Inc | Stabilized prostaglandin preparations |
| US3875300A (en) * | 1972-12-18 | 1975-04-01 | Ortho Pharma Corp | Composition for sustained release of a medicament and method of using same |
| US4136162A (en) * | 1974-07-05 | 1979-01-23 | Schering Aktiengesellschaft | Medicament carriers in the form of film having active substance incorporated therein |
| US5017382A (en) * | 1979-03-21 | 1991-05-21 | National Research Development Corporation | Controlled release compositions (II) |
| JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS5948409A (ja) * | 1982-09-10 | 1984-03-19 | Teikoku Seiyaku Kk | 矯正的歯牙移動促進剤 |
| JPS6185315A (ja) * | 1984-10-04 | 1986-04-30 | Teikoku Seiyaku Kk | シ−ト状製剤 |
| IE59361B1 (en) * | 1986-01-24 | 1994-02-09 | Akzo Nv | Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension |
| US5219885A (en) * | 1987-02-16 | 1993-06-15 | Froelich Juergen | Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration |
| BR9203277A (pt) * | 1992-08-21 | 1994-03-01 | Cesar Roberto Dias Nahoum | Utilizaccao de drogas eretogenicas e respectivas metodologias de aplicacao |
| US5380760A (en) * | 1993-11-19 | 1995-01-10 | Minnesota Mining And Manufacturing Company | Transdermal prostaglandin composition |
| SE9501670L (sv) * | 1995-05-05 | 1996-06-10 | Perstorp Ab | Omläggningsset |
| US6593369B2 (en) * | 1997-10-20 | 2003-07-15 | Vivus, Inc. | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
| US20020004529A1 (en) * | 1997-10-20 | 2002-01-10 | Gary W. Neal | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
| US6414028B1 (en) * | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
| US6046244A (en) * | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
| US5942545A (en) * | 1998-06-15 | 1999-08-24 | Macrochem Corporation | Composition and method for treating penile erectile dysfunction |
| JP2002518417A (ja) * | 1998-06-25 | 2002-06-25 | ラヴィファム ラボラトリーズ インコーポレーテッド | 勃起機能不全の治療装具及び方法 |
| US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
| KR100402334B1 (ko) * | 2000-06-23 | 2003-10-22 | 환인제약 주식회사 | 알프로스타딜 외용제 |
-
2003
- 2003-01-03 US US10/336,481 patent/US6841574B2/en not_active Expired - Lifetime
- 2003-12-31 KR KR1020057012502A patent/KR20050098853A/ko not_active Application Discontinuation
- 2003-12-31 BR BR0317924-9A patent/BR0317924A/pt not_active Application Discontinuation
- 2003-12-31 KR KR1020117008180A patent/KR101174788B1/ko not_active IP Right Cessation
- 2003-12-31 PT PT03800371T patent/PT1585483E/pt unknown
- 2003-12-31 JP JP2004566647A patent/JP2006514068A/ja active Pending
- 2003-12-31 ES ES03800371T patent/ES2343246T3/es not_active Expired - Lifetime
- 2003-12-31 DK DK03800371.1T patent/DK1585483T3/da active
- 2003-12-31 EP EP03800371A patent/EP1585483B1/fr not_active Expired - Lifetime
- 2003-12-31 CA CA2512015A patent/CA2512015C/fr not_active Expired - Lifetime
- 2003-12-31 WO PCT/US2003/041658 patent/WO2004062632A1/fr active Application Filing
- 2003-12-31 DE DE60332656T patent/DE60332656D1/de not_active Expired - Lifetime
- 2003-12-31 AU AU2003300113A patent/AU2003300113B2/en not_active Expired
- 2003-12-31 AT AT03800371T patent/ATE468098T1/de active
- 2003-12-31 CN CN200380110112A patent/CN100574763C/zh not_active Expired - Fee Related
-
2005
- 2005-06-27 IL IL169425A patent/IL169425A/en unknown
- 2005-06-30 ZA ZA200505321A patent/ZA200505321B/en unknown
-
2006
- 2006-10-05 HK HK06111022.3A patent/HK1090293A1/xx not_active IP Right Cessation
-
2011
- 2011-09-14 JP JP2011200752A patent/JP5395138B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR0317924A (pt) | 2005-11-29 |
| EP1585483A1 (fr) | 2005-10-19 |
| IL169425A (en) | 2010-11-30 |
| HK1090293A1 (en) | 2006-12-22 |
| DE60332656D1 (de) | 2010-07-01 |
| CN1756532A (zh) | 2006-04-05 |
| US6841574B2 (en) | 2005-01-11 |
| EP1585483A4 (fr) | 2006-04-19 |
| JP2006514068A (ja) | 2006-04-27 |
| ATE468098T1 (de) | 2010-06-15 |
| CA2512015C (fr) | 2011-11-08 |
| KR101174788B1 (ko) | 2012-08-20 |
| KR20050098853A (ko) | 2005-10-12 |
| WO2004062632A1 (fr) | 2004-07-29 |
| JP2012036196A (ja) | 2012-02-23 |
| CN100574763C (zh) | 2009-12-30 |
| AU2003300113B2 (en) | 2010-03-11 |
| DK1585483T3 (da) | 2010-07-19 |
| CA2512015A1 (fr) | 2004-07-29 |
| AU2003300113A1 (en) | 2004-08-10 |
| KR20110042138A (ko) | 2011-04-22 |
| EP1585483B1 (fr) | 2010-05-19 |
| JP5395138B2 (ja) | 2014-01-22 |
| US20040131664A1 (en) | 2004-07-08 |
| PT1585483E (pt) | 2010-06-17 |
| ES2343246T3 (es) | 2010-07-27 |
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