ZA200503461B - Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof - Google Patents

Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof Download PDF

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Publication number
ZA200503461B
ZA200503461B ZA200503461A ZA200503461A ZA200503461B ZA 200503461 B ZA200503461 B ZA 200503461B ZA 200503461 A ZA200503461 A ZA 200503461A ZA 200503461 A ZA200503461 A ZA 200503461A ZA 200503461 B ZA200503461 B ZA 200503461B
Authority
ZA
South Africa
Prior art keywords
gel
biocompatible
cohesive biopolymer
biopolymer gel
dextran sulfate
Prior art date
Application number
ZA200503461A
Other languages
English (en)
Inventor
Nevo Zvi
Astachov Liliana
Rochkind Semion
Shahar Abraham
Original Assignee
Nvr Labs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nvr Labs Ltd filed Critical Nvr Labs Ltd
Publication of ZA200503461B publication Critical patent/ZA200503461B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02Dextran; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/32Materials or treatment for tissue regeneration for nerve reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Peptides Or Proteins (AREA)
ZA200503461A 2002-09-30 2005-04-29 Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof ZA200503461B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15203002A IL152030A0 (en) 2002-09-30 2002-09-30 Cohesive biopolymers comprising sulfated polysaccharides and fibrillar proteins and use thereof for tissue repair

Publications (1)

Publication Number Publication Date
ZA200503461B true ZA200503461B (en) 2007-01-31

Family

ID=29765027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200503461A ZA200503461B (en) 2002-09-30 2005-04-29 Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof

Country Status (8)

Country Link
US (1) US20060110426A1 (fr)
EP (1) EP1549295A4 (fr)
JP (1) JP2006506110A (fr)
AU (1) AU2003269440A1 (fr)
CA (1) CA2501009A1 (fr)
IL (1) IL152030A0 (fr)
WO (1) WO2004029095A2 (fr)
ZA (1) ZA200503461B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1748781E (pt) 2004-05-27 2013-01-22 Baxter Int Processos para o tratamento de distúrbios de hemorragias utilizando polissacarídeos sulfatados
WO2006033103A2 (fr) * 2004-09-21 2006-03-30 Nvr Labs. Ltd. Compositions et methodes servant a l'expansion et a la differenciation de cellules souches
FR2881434B1 (fr) * 2005-02-02 2007-05-11 Coletica Sa Dispositif de support de culture de cellules
CN100382772C (zh) * 2005-09-28 2008-04-23 南通大学 含蚕丝丝素的医用神经移植物的制备方法
EP2259803B2 (fr) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Dispositif pour la promotion de l homéostasie et/ou la cicatrisation des plaies
AU2009284393B2 (en) 2008-08-22 2014-09-25 Takeda Pharmaceutical Company Limited Methods for treating bleeding disorders
DE102008059857A1 (de) * 2008-12-01 2010-06-02 Forschungsinstitut für Leder und Kunststoffbahnen gGmbH Mit Kohlenhydrat-Derivaten additivierte Gelatinezusammensetzungen
WO2010076798A1 (fr) * 2009-01-02 2010-07-08 Ramot At Tel Aviv University Ltd. Matrices de fibrine et de fibrinogène et leurs applications
EP2498830B1 (fr) * 2009-11-11 2016-09-21 University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) Hydrogels à base de dextrane-acide hyaluronique
US8632991B2 (en) 2010-01-14 2014-01-21 Baxter International Inc. Methods and compositions for treating bleeding disorders
EP2734213B1 (fr) 2011-07-19 2018-06-06 Baxalta GmbH Activateurs de résorption comme additifs pour améliorer la formulation orale de polysaccharides sulfatés non anticoagulants
CA2865349C (fr) 2012-03-06 2021-07-06 Ferrosan Medical Devices A/S Recipient mis sous pression contenant de la pate hemostatique
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
EP3594686A3 (fr) 2012-08-14 2020-04-08 Baxalta GmbH Procédés et systèmes de criblage de compositions comprenant des polysaccharides sulfatés non anticoagulants
US9421221B2 (en) * 2012-11-12 2016-08-23 Warsaw Orthopedic, Inc. Compositions and methods for inhibiting adhesion formation
US9474767B2 (en) * 2012-11-12 2016-10-25 Warsaw Orthopedic, Inc. Compositions and methods for inhibiting bone growth
RU2700162C2 (ru) 2013-06-21 2019-09-13 Ферросан Медикал Дивайсиз А/С Расширенная под вакуумом сухая композиция и шприц для ее сохранения
US9981067B2 (en) 2013-09-30 2018-05-29 Bioactive Regenerative Therapeutics, Inc. Biomimetic hybrid gel compositions and methods of use
EP3079731B1 (fr) 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Composition sèche comprenant un améliorateur d'extrusion
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
WO2016102446A1 (fr) 2014-12-24 2016-06-30 Ferrosan Medical Devices A/S Seringue pour retenir et mélanger des première et seconde substances
CA2986981A1 (fr) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Seringue pour melanger deux composants et pour conserver un vide dans une condition de stockage
KR20210008479A (ko) 2018-05-09 2021-01-22 훼로산 메디칼 디바이스 에이/에스 지혈 조성물을 제조하는 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352707B1 (en) * 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
US5571166A (en) * 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
US5783214A (en) * 1994-06-13 1998-07-21 Buford Biomedical, Inc. Bio-erodible matrix for the controlled release of medicinals
AU737348B2 (en) * 1994-08-12 2001-08-16 Meadox Medicals, Inc. Vascular graft impregnated with a heparin-containing collagen sealant
AU700584C (en) * 1994-08-12 2002-03-28 Meadox Medicals, Inc. Vascular graft impregnated with a heparin-containing collagen sealant
AU725654B2 (en) * 1996-05-03 2000-10-19 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
CA2476653C (fr) * 2002-02-21 2009-01-27 Encelle, Inc. Matrices d'hydrogel bioactif reticule

Also Published As

Publication number Publication date
AU2003269440A1 (en) 2004-04-19
WO2004029095A2 (fr) 2004-04-08
IL152030A0 (en) 2003-05-29
JP2006506110A (ja) 2006-02-23
US20060110426A1 (en) 2006-05-25
EP1549295A2 (fr) 2005-07-06
WO2004029095A3 (fr) 2004-06-03
CA2501009A1 (fr) 2004-04-08
EP1549295A4 (fr) 2007-08-15

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