ZA200203383B - Mimetic peptides for epitope of apolipoprotein B-100, concatemer and modified peptides thereof, and the vaccine composition comprising the same. - Google Patents

Mimetic peptides for epitope of apolipoprotein B-100, concatemer and modified peptides thereof, and the vaccine composition comprising the same.

Info

Publication number
ZA200203383B
ZA200203383B ZA200203383A ZA200203383A ZA200203383B ZA 200203383 B ZA200203383 B ZA 200203383B ZA 200203383 A ZA200203383 A ZA 200203383A ZA 200203383 A ZA200203383 A ZA 200203383A ZA 200203383 B ZA200203383 B ZA 200203383B
Authority
ZA
South Africa
Prior art keywords
peptides
apolipoprotein
epitope
vaccine composition
mimetic
Prior art date
Application number
ZA200203383A
Inventor
Hae-Jung Joung
Hyo-Joon Kim
Original Assignee
Hyo-Joon Kim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyo-Joon Kim filed Critical Hyo-Joon Kim
Publication of ZA200203383B publication Critical patent/ZA200203383B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0012—Lipids; Lipoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: Provided are mimetic peptides for epitope of apolipoprotein b-100, their concatemers and modified peptides, and a vaccine composition comprising them. The vaccine composition is used for the treatment of obesity. CONSTITUTION: The mimetic peptides for epitope of apolipoprotein B-100 are represented by the SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3. Their concatemers consist of 1-15, preferably 4 mimetic peptides. The vaccine composition for the treatment of obesity contains them and is formulated into an intradermal injection. Their manufacturing method comprises the steps of: inserting DNA coding mimetic peptides for epitope of apolipoprotein b-100, their concatemers and modified peptides, into a vector; transforming a strain with the vector then culturing it; and separating mimetic peptides for epitope of apolipoprotein b-100, their concatemers and modified peptides from the culture.
ZA200203383A 2000-09-04 2002-04-29 Mimetic peptides for epitope of apolipoprotein B-100, concatemer and modified peptides thereof, and the vaccine composition comprising the same. ZA200203383B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20000052055 2000-09-04

Publications (1)

Publication Number Publication Date
ZA200203383B true ZA200203383B (en) 2002-12-10

Family

ID=19687156

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200203383A ZA200203383B (en) 2000-09-04 2002-04-29 Mimetic peptides for epitope of apolipoprotein B-100, concatemer and modified peptides thereof, and the vaccine composition comprising the same.

Country Status (4)

Country Link
KR (1) KR100472841B1 (en)
AT (1) ATE485053T1 (en)
DE (1) DE60143300D1 (en)
ZA (1) ZA200203383B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100639397B1 (en) * 2004-03-18 2006-10-26 (주)에스제이바이오메드 Anti-obese immuogenic hybrid polypeptides and anti-obese vaccine composition comprising the same
EP2076544A4 (en) 2006-09-25 2009-11-11 Sj Biomed Inc Anti-obese immunogenic hybrid polypeptides and anti-obese vaccine composition comprising the same
BR112023000620A2 (en) 2020-07-22 2023-03-28 3H Bio Co Ltd PEPTIDE USED FOR IMMUNOTHERAPEUTICS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5408038A (en) * 1991-10-09 1995-04-18 The Scripps Research Institute Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides
KR100330310B1 (en) * 1998-06-18 2002-08-08 한국과학기술연구원 New Monoclonal Antibodies to Human Plasma Apolipoprotein B-100 and Hybridoma Cell Lines Producing Them

Also Published As

Publication number Publication date
DE60143300D1 (en) 2010-12-02
KR100472841B1 (en) 2005-03-07
ATE485053T1 (en) 2010-11-15
KR20020018971A (en) 2002-03-09

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