ZA200100020B - Salts of paroxetine. - Google Patents

Salts of paroxetine. Download PDF

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Publication number
ZA200100020B
ZA200100020B ZA200100020A ZA200100020A ZA200100020B ZA 200100020 B ZA200100020 B ZA 200100020B ZA 200100020 A ZA200100020 A ZA 200100020A ZA 200100020 A ZA200100020 A ZA 200100020A ZA 200100020 B ZA200100020 B ZA 200100020B
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South Africa
Prior art keywords
acid
benzoic
phenyl
methyl
carboxylic
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ZA200100020A
Inventor
Jacewicz Victor Witold
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Smithkline Beechan Plc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Description

: SALTS OF PAROXETINE
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
Pharmaceutical products with antidepressant and anti-Parkinson properties are described in
US-A-3912743 and US-A-4007196. An especially important compound among those disclosed is paroxetine, the (-)trans isomer of 4-(4'-fluorophenyl)-3-(3',4'-methylenedioxy- phenoxymethy!)-piperidine. This compound is used in therapy as the hydrochloride salt for the treatment and prophylaxis of inter alia depression, obsessive compulsive disorder (OCD) and panic.
The present invention provides novel salts of paroxetine which may be used as an alternative to the currently marketed hydrochloride, or as an intermediate in the preparation of the hydrochloride.
According to the present invention there is provided a salt of paroxetine with an acid selected from the group consisting of: 2-methyl-3-phenylbutyric acid } tricyclo(10.2.2.2(4,7))octadeca-hexaene-9.10-dicarboxylic acid 1-pyreneacetic acid 2.4 6-trifluorocinnamic acid 2-bromoisobutyric acid cyclohexylsuccinic acid 3,5-dichloro-2,6-dimethoxybenzoic acid 5-ethoxy-2-hydroxybenzoic acid trans-11-eicosenoic acid 3-bromopropionic acid 3-[5-(4-bromo-phenyl)-furan-2-yl}-acrylic acid 2-phenylacrylic acid 21-docosenoic acid
Tr TO VIR. Cu Ce Co BR n-(p-amylcinnamoyl)anthranilic acid (2'methyl 4'amino) phenyl azo naphthylene 3,8 disuifonic acid 7,7-dimethyleicosadienoic acid 2,5-dibromobenzenesulfonic acid 5,7-eicosadiynoic acid nonadec-18-enoic acid 3-methoxycyclohexanecarboxylic acid 5-chloro-2-thiophenecarboxylic acid beta-naphthyl phosphate 2-(1,4-benzodioxan-2-yl)thiazole-4-carboxylic acid 2-methyl-1,6-naphthyridine-3-carboxylic acid (10-ho-10-ph-4h-8-thia-7,10a-diaza-pentaleno(1,2-a)naphthalen-9-yl)-acetic acid fmoc-isonipecotic acid 4-(3-(2-fluoro-5-nitrophenyl)ureido)benzoic acid n-ethylmaleamic acid 7-methoxycoumarin-4-acetic acid trans-4-n-pentylcyclohexanecarboxylic acid 2.4-dimethylcinnamic acid (s)-3-methylnonanoic acid 3-maleimidobenzoic acid acetoxyvalerenic acid 7.12-dimethylbenz(a)anthracene-5-carboxylic acid 4-chlorophthalic acid 2-(carboxymethyl-amino)-6-chloro-benzoic acid 3'-methoxyphthalanilic acid
I-(+)-2-amino-6-phosphonohexanoic acid (1)-2,3-diacetoxy-n-(1-(1-naphthyl)ethyl)succinamic acid 4-fluorophenoxydifluoroacetic acid 3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid 3-(4-(2-carboxy-ethyl)-2,5-dimethoxy-phenyl)-propionic acid 6-(6-hydroxy-3-oxo-3h-xanthen-9-yl)-3-cyclohexene- 1-carboxylic acid cis-n-tert-butylhexahydrophthalamic acid
2,5-dihydroxycinnamic acid 3-bromo-2-(bromomethyl)propionic acid 3-ethyl-3-phenylglutaric acid alpha-(2,4-dimethoxy-6-methylbenzylidene)hippuric acid 5-phenylvaleric acid (+/-)-2-amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4-yl]propi onic acid 4-aminonicotinic acid p-fluoro-alpha-acetamidocinnamic acid 2.5-dihydroxybenzoic acid 10-(1-pyrene)-10-ketodecanoic acid 2-chloro-3,5-dinitrobenzoic acid p-azoxy benzoic acid
2-ethylthio-2,2-diphenylacetic acid 4-(3-cinnamoyl-2-thioureido)benzoic acid 2-hydroxydibenzofuran-3-carboxylic acid 2-(3,5-dinitro-thiophen-2-ylamino)-pentanoic acid 2-benzoylamino-cyclohexanecarboxylic acid 3-hydroxyhomophthalic acid
2.5-dibromobenzoic acid 4-(2-chloro-2-cyanoethyl)-benzoic acid 2-methylhydrocinnamic acid
13-methylpentadecanoic acid
3,4,5-trimethoxyphenylacetic acid d1-2-hydroxy-4-(methylthio)butyric acid
2-oxoadipic acid bromoacetic acid
1-(4-isopropyl-3-methyl-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid perfluoroazelaic acid acetyl syringic acid
3'-acetyiphthalanilic acid alpha-bromophenylacetic acid
3-(3,4-diacetoxy-5-methyl-phenyl)-acrylic acid p-iodocinnamic acid 4,4'-methylenebis(maleanilic acid) 3-(4-trifluoromethylsulfanyl-phenylcarbamoyl)-acrylic acid 3-[2-(pyrazin-2-yl)-1-[4-(trifluoromethyl)phenyljethoxy]propanoic acid 2-phenoxybutyric acid 2-[4-chloro(phenylsulfonyl)anilino]acetic acid boc-dl-beta-aminobutyric acid 3,5-dinitrobenzoic acid 4-tert-butylcyclohexanecarboxylic acid (r)-2.2-dimethyl-3-formyl 4-thiazolidinecarboxylic acid (2s.4s)-(-)-azetidine-2,4-dicarboxylic acid 2-(4-nitro-phenyl)-3-phenyl-acrylic acid 3-nitrobenzoic acid 10,1 1-dihydro-dibenzo(b,f)oxepine-4,6-dicarboxylic acid (2-isopropyl-5-oxo-cyclohexyloxy)-acetic acid (s)-(-)-n-(1-phenylethyl)succinamic acid 6-(2-bromobenzoyl)hexanoic acid (1alpha,3alpha,Sbeta)-1,3,5-trimethyl-1,3.5-cyclohexanetricarboxylic acid 2-methylpropane tricarboxylic acid 5-(4-hydroxymethyl-3-methoxyphenoxy)valeric acid n-(3,4-dicyano-phenyl)-phthalamic acid 5-fluorosalicylic acid itaconic acid 2.2-dimethyl-cyclobutane-1,1,3,3-tetracarboxylic acid 8-hydroxy-5-(4-sulfophenylazo)-2-naphthalenesulfonic acid 3-(4-chlorophenylthio)butyric acid n-benzylglutaramic acid 3-(2,5-dimethoxybenzoyl)propionic acid 4-cyanocinnamic acid
2-(4-methoxy-phenyl)-1 3-dioxo-2,3-dihydro-1h-isoindole-5-carboxylic acid 2-hydroxyimino-pentanedioic acid 6-methyl-1 ,3-benzodioxole-5-carboxylic acid 2-(4-hydroxyphenoxy)propionic acid 7h-dodecafluoroheptanoic acid 3' 5'-dimethylmaleanilic acid 2-butyl-5-tert-butyl-isophthalic acid 4-chloro-2-phthalimidobenzoic acid 2-methyl-1,3-dithiolane-2-propionic acid 4-chloro-2-nitrophenol-6-sulfonic acid n-methyl-l-glutamic acid 4,6,2' 4'-tetranitro-biphenyl-2-carboxylic acid (r)-(-)-2-amino-2-methylbutanedioic acid 3-[2-(4-tert-butylphenoxy)-5-nitro phenyljacrylic acid 4-(trifluoromethylthio)phenylacetic acid dithiodiglycolic acid n.n-bis-(phosphonomethyl)-glycine 3-(10-(2-carboxy-ethyl)-anthracen-9-yl)-propionic acid hydrocinnamic acid 3,6-dichloro-5-hydroxy-o-anisic acid 3,5-difluorophenylacetic acid 2'-(trifluoromethyl)succinanilic acid cis-5,8,11,14,17-eicosapentaenoic acid 3,3'-(dimethylsilylene)bispropionic acid 1-(3-chloro-3-trifluoromethyl-2-pyridyl)pyrrole-2-caroxylic acid n-(4,6-dimethylpyrimidin-2-yl)-4-aminobenzoic acid 10,12-docosadiyndioic acid 6,6-dimethyl-3-(methylthio)-4,5,6,7-tetrahydrobenzo(c]thiophen -4-one-1-carboxylic acid gentisuric acid 2-fluoro-4-heptyloxybenzoic acid 2-(4-chloro-3-nitrobenzoyl)benzoic acid
3-(4-bromo-2-thienyl)acrylic acid 3,5-dimethoxycinnamic acid 3-((2-carboxy-ethyl)-(1,3,4)thiadiazol-2-yl-amino)-propionic acid 4 sulfo anthranilic acid d-pyroglutamic acid (2,5-xylyl)phosphonic acid 3-bromo-5-methoxy-benzo(b)thiophene-2-carboxylic acid 4.5.5.6,6.6-hexafluoro-4-(trifluoromethyl)-2-hexenoic acid 2,3-difluorophenylacetic acid 3,3,3-trifluoro-dl-lactic acid 3-[4-(4-methylphenylthio)-3-nitrophenyljacrylic acid 2.8-dimethoxy-dodecahydro-dibenzofuran-1-carboxylic acid 4-cyclohexylbenzoic acid boc-d-1,2.3.4-tetrahydronorharman-3-carboxylic acid 2-benzyl-cyclohexanecarboxylic acid 3-{(4-fluoro-phenyl)-(toluene-4-sulfonyl)-amino]-propionic acid 3-(2,4,5-trimethyl-phenyl)-butyric acid 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyric acid chelidamic acid 4-(4-(1-methyl-1 h-quinolin-4-ylidene)-but-2-enylideneamino)-benzoic acid 8-carbamoylnaphthalene-1-carboxylic acid n-(m-tolyl)succinamic acid n-(1-naphthyl)phthalamic acid 3-(3,4-dihydro-naphthalen-1-yl)-propionic acid 4-(2-phenylsulfanyl-acetylamino)-benzoic acid perfluoroheptanoic acid 4'-chloro-2'-methylphthalanilic acid diethylphosphonopentanoic acid 2-(3-methoxy-benzylidene)-pentanedioic acid 4 4'-biphenyldicarboxylic acid 18-methylnonadecanoic acid
4 -(n-methylacetamido)glutaranilic acid (+)-3-methyladipic acid 7-bromo-3-methoxythiophene-4-carboxylic acid (5-(4-chloro-phenyl)-pyrimidin-4-ylsulfanyl)-acetic acid glycyl-d-aspartic acid 3-(n-(3,4-dichlorophenyl)carbamoyl)-5-norbornene-2-carboxylic acid n-(3-bromo-2,4,6-trimethylphenylcarbamoylmethyl)iminodiacetic acid 1,2,3,4,5,6-cyclohexanehexacarboxylic acid alpha-(phenylthio)phenylacetic acid geranic acid 5-hydroxy-2-(1-octynyl)-3-oxo- 1-cyclopentene-1-heptanoic acid n-fmoc-2-aminoindan-2-carboxylic acid 3-(9,10-diox0-9.1 0-dihydro-anthracen-2-yl)-acrylic acid p-tolylacetic acid 4-(4-(4-tolyl)butyl)phenylacetic acid 2-methylcyclopropanecarboxylic acid 4-chloro-alpha,alpha-dimethylphenylacetic acid (2,4-dichloro-3-methylphenylthio)acetic acid 3-(3,4-dichlorobenzylthio)thiophene-2-carboxylic acid (+)-3-methyl-2-phenylbutyric acid 3-cyclopentenecarboxylic acid n-tris(hydroxymethy!)methyl-2-amino-ethanesulphonic acid (s)-5-oxotetrahydrofuran-2-carboxylic acid 5-benzoylthiophene-2-acetic acid p-toluenesulfonic acid 3,6-dimethyl-cyclohex-4-ene-1 ,2-dicarboxylic acid 3-(2-chlorophenyl)-5-methyl isoxazole-4-carboxylic acid 1-(4-acetylphenyl)isonipecotic acid phenyl-o-tolyl-phosphinic acid 2-(1 -(2-(3 4-dimethoxy-phenyl)-ethyl)-5-ethyl-2-oxo-piperidin-4-yl)-malonic acid n-(4-methoxyphenyl)malonic acid
(+)-3-pinanecarboxylic acid 2-(2,4,5-trichlorophenoxy)-propionic acid 10-hydroxydecanoic acid : 5-(3-chloro-phenyl)-pentanoic acid 4-{[[4-[(46-dimethylpyrimidin-2-yl)thio]phenylJamino]-4-oxo-(22)-butenoic acid 2_acetamido-3-(4'-chlorophenyl)-acrylic acid 2-hydroxy-6-[3-(trifluoromethyl)phenyl]-3,5-pyridinedicarboxylic acid 9-hydroxyimino-9h-fluorene-4-carboxylic acid mucochloric acid 4-methyl-1-naphthoic acid 2-naphthyl acrylic acid 4-hexyl-cyclohexanecarboxylic acid 4-(3,5-dimethyl-naphthalen-2-y1)-3-methyl-pentanoic acid n.n,n".n'-ethylenediaminetetra(methylenephosphonic acid) 6-heptynoic acid 2-(4-methoxybenzylidene)succinic acid (r)-(+)-2-chloropentanoic acid 2-(3-chloro-4-methoxy-phenylamino)-benzoic acid 3,5-bis(trifluoromethyl)cinnamic acid 4-hexyloxybiphenyl-4'-carboxylic acid (+/-)-10-camphorsulfonic acid 4 4'-oxybisbutanoic acid 2-methyl decanoic acid 4-biphenylcarboxylic acid 3-chloro-n-butyric acid 3-anthracen-2-yl-acrylic acid (s,s)-(+)-2,3-diphenylsuccinic acid 10-methyldodecanoic acid 4'-fluorosuccinanilic acid 2-bromo-3-methylbenzoic acid n-(4-trifluoromethoxypheny!)malonamic acid
3-(2-thienyl)acrylic acid
3-(3-methoxyphenoxy)propionic acid 2,3,6-trifluorocinnamic acid 3-chloroadamantane-1-carboxylic acid 2,5-dichloro-alpha-methyl-3-thiopheneacrylic acid 2-ho-10-methanesulfonyl-9-oxa-tricyclo(6.2.1.0(1,5))undecane-4-carboxylic acid 2.2-dichlorooctanoic acid
7-chloro-6-fluoro-1-ethyl-4-oxoquinoline-3-carboxylic acid acetoxy decanoic acid
5-bromovaleric acid meso-2,3-bis(benzylamino)succinic acid 3.6-dimethyl-4,5-diphenyl-cyclohexa-3.5-diene-1.2-dicarboxylic acid dodecafluoro-2-methyl-3-oxahexanoic acid dl-2-(4-methoxyphenyl)butyric acid 3-(n,n-diethylcarbamoyl)-5-norbornene-2-carboxylic acid o-carboxypheny! phosphate n-boc-2-aminoindane-2-carboxylic acid
9-hydroxynonanoic acid
3-(2,5-dimethoxy-phenyl)-propionic acid 4-((2-hydroxy-3-nitro-benzylidene)-amino)-benzoic acid fmoc-10-aminodecanoic acid thiophene-2.5-dicarboxylic acid
2-bromophenylacetic acid
3-(3.4-methylenedioxyphenyl)propionic acid
(z)-styrylsulphonylpropionic acid
2'-carboxymaleanilic acid gamma-0Xo- | -naphthalenebutyric acid
11-((5-dimethylaminonaphthalene- 1-sulfonyl)amino)undecanoic acid 2-[[(4-chlorophenyl)sulfonyl]-3-(trifluoromethyl)anilinojacetic acid
2-nonenoic acid
2-formylphenoxyacetic acid
2,4-pyridinedicarboxylic acid 2-fluoro-6-(trifluoromethyl)phenylacetic acid acenaphthene-3-carboxylic acid 2-fluoro-6-hydroxybenzoic acid 4~((pyridin-3-ylmethylene)-amino)-benzoic acid 4-isobutylbenzoic acid diheptyl-phosphinic acid 3-chloropivalic acid 2-(2-nitro-4-(trifluoromethyl)phenyl)acetic acid 2.5-dichlorobenzoic acid 4-methoxy-3-methylbenzoic acid 2-fluoro-5-methoxybenzoic acid 14(s),15(r)-epoxy-(5z.8z.1 1 z)-eicosatrienoic acid (2-(1-phenyl-ethyl)-phenoxy)-acetic acid 4-(benzenesulfonamido)-salicylic acid 4-hydroxy-3-iodo-5-nitro-phenylacetic acid 2.6-dihydroxy-3,5-dimethyl-benzoic acid 2.4-dimethoxy-6-methyl-benzoic acid n-(2-thiazolyl)succinamic acid 7-(3,3-dimethyl-2,3-2h-benzo(b)thiophen-5-yl)-3-methyl-octa-2,4,6-trienoic acid r-4-nitromandelic acid (1r)~(-)-10-camphorsulfonic acid 2-fluoro-4-(trifluoromethy!l)cinnamic acid 3-(4-tert-butyl-phenylsulfanyl)-propionic acid 2-(3,5-dinitro-thiophen-2-ylamino)-succinic acid (2-((3,4-dimethoxy-phenyl)-acetyl)-5-methoxy-phenyl)-acetic acid 3,5-diiodosalicylic acid 2-(3-chlorophenoxy)propionic acid erythro-9,10-dihydroxystearic acid nitrous acid . shikimic acid
2'-me-1,3,1',3'-tetraoxo-1,3 ,2',3'-4h-1 'h-(2,5")biisoindolyl-5-carboxylic acid alpha3-chloro-5,7-dimethyl-1 ,3-adamantanediacetic acid 4-(4-pentyl-cyclohexyl)-benzoic acid 3-methyl-2-(toluene-4-sulfonylamino)-butyric acid (s)-1 -amino(3-methylbutane)phosphonic acid 5-benzyloxy-4-methoxy-2-methyl-benzoic acid 4'-bromo-2'-chlorohexahydrophthalanilic acid 2-pentynoic acid 2-benzofurancarboxylic acid 3-(p-tolylthio)propionic acid 2-cyano-3-ethoxyacrylic acid 2-[3-(n"-octanoyl-hydrazino)-3-oxo-propionylamino}-benzoic acid 4-hydroxy-3-nitroso-1-naphthalenesulfonic acid 3-iodo-4-(isopropylsulphonyl)-5-(methylthio)thiophene-2-carboxylic acid n-boc-I-1,2,3 4-tetrahydroisoquinoline-3-carboxylic acid 3-(1-naphthylthio)propionic acid 2.4 6-trimethylbenzoic acid bicyclo(2.2.1)heptane-3,4-dicarboxylic acid 1,1 '_ethylenebis(5-oxo0-3-pyrrolidinecarboxylic acid) rhodanine-3-acetic acid nitranilic acid (r)-(-)-2-hydroxy-2-phenylpropionic acid methylthiohydantoin-dl-aspartic acid 6-methyl-2-pyridin-3-yl-quinoline-4-carboxylic acid citraconic acid : n-(acetoacetyl)anthranilic acid n-(3-ethoxyphenyl)maleamic acid 2' 4'-difluorophthalanilic acid 2 4-dimethoxycinnamic acid 12-me-tricyclo(8.2.2.2(4,7))hexadeca-hexaene-5-carboxylic acid [2-(propane-2-sulfonyl)-acetylamino}-acetic acid
2-hydroxydecanoic acid - cis-n-benzylhexahydrophthalamic acid 1,4-phenylenediacrylic acid (2~(4-methoxy-phenyl)-6-oxo-cyclohex-1-enyl)-acetic acid 2-(5-fluoro-1-naphthoyl)benzoic acid (2,2,2-trichloro-1-(3-(4-methoxycarbonyl-ph)-thioureido)-ethyl)-carbamic acid 2-[3-(n'-benzoyl-hydrazino)-3-oxo-propionylamino]-benzoic acid dl-p-aminobenzylsuccinic acid 2-isopropyl-2-phenylacetic acid fmoc-(3s,4s,5s)-4-amino-3-hydroxy-5-methyl-heptanoic acid 2-chloroisonicotinic acid 3,4.4-trichloro-but-3-enoic acid 1-(4-chlorophenyl)-1-cyclobutanecarboxylic acid 4-(4-(4-chloro-phenoxy)-benzenesulfonyl)-benzoic acid (4-acetylamino-benzenesulfonylsulfanyl)-acetic acid } n-(4-aminobenzoyl)-1-glutamic acid 4-(3-phenylureido)butyric acid 2'-fluoro-3.,4,5,6-tetrachlorophthalanilic acid 4-sulfobenzoic acid ascorbyl palmitate [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioJacetic acid 2-amino-4-phenylthiazole-3-carboxylic acid 4-hydroxy-5-methoxy-1-phenyl-naphthalene-2-carboxylic acid 3,4,5-trimethyl-1h-pyrrole-2-carboxylic acid 3,3',4,4'-benzophenonetetracarboxylic acid 4'-chloro-2',5'-dimethoxyhexahydrophthalanilic acid 3-(4-ethoxybenzoyl)propionic acid 4-chloro-2,6-dimethyl-nicotinic acid 3-[2-(4-butoxy-benzoylamino)-3-(4-methoxy-phenyl)-acryloylamino]-propionic acid 2-methylthiobenzimidazolesulfonic acid phenaceturic acid alpha, beta-dibromocinnamic acid o-trifluoromethyl-alpha-acetamidocinnamic acid boc-d-alpha-amino-gamma-(4-methylbenzylmercapto)-butyric acid n-alpha-(benzyloxycarbonyl)-d-aspartic acid 2-fluoro-4-pentyloxybenzoic acid boc-(3s,4s)-4-amino-3-hydroxy-5-phenyl-pentanoic acid pyruvic acid 4-(2-chlorophenoxy)-3-nitrocinnamic acid 3-(aminocarbonylmethylthio)thiophene-2-carboxylic acid chlorobenzoyl(4-) benzoic acid 3-phenyl-2-p-tolyl-propionic acid 7-hydroxycoumarin-4-acetic acid 2.3.4-trifluorobenzoic acid 3-acetyl-2-phenyl-4-thiazolidinecarboxylic acid 2-(3-(2,2,2-trichloro-1-((furan-2-carbonyl)-amino)-et)-thioureido)-benzoic acid 2-(3-chloro-benzoyl)-benzoic acid n-phthaloyl-gly-dl-alpha-amino-n-butyric acid 2-naphthoic acid cyclooctane-1,2-dicarboxylic acid 4.4'-dicarboxydiphenyl sulfone 3-(4-n-heptyloxybenzoyl)propionic acid n-(4-methoxyphenyl)maleamic acid 3-((2-carboxy-ethyl)-(6-methyl-benzothiazol-2-yl)-amino)-propionic acid 3,6-diphenyl-cyclohex-4-ene-1,2-dicarboxylic acid 5-(3-bromobenzoyl)pentanoic acid diisooctyldithiophosphinic acid 5-bromo-2-furoic acid 1,2,3,4-tetrahydro-phenanthrene-1,2-dicarboxylic acid 9-ethyl-3-carbazolephosphonous acid 4-(2-hydroxy-6-(trimethylsilyl)-1-naphthylazo)benzoic acid ethylmalonic acid cyclobutyl phenylglycolic acid 3-bromophenylacetic acid n-(2-carboxyethyl)iminodiacetic acid 4-(tert-butyl)benzamidoacetic acid fmoc-11-aminoundecanoic acid fmoc-l-octahydroindole-2-carboxylic acid 2-(3-(4-(4,4-dicarboxy-butyl)-phenyl)-propyl)-malonic acid 3-(4-methylbenzamido)benzoic acid a 1-(2-benzo|1,3]dioxol-5-yl-et)-2-(2-carboxy-et)-oxo-pyrrolidine-carboxylic acid 4-hydroxy-3.5-diisopropyl-benzoic acid 3-((2-carboxy-ethyl)-phenyl-amino)-propionic acid p-phenylazomaleanilic acid 2-bromoacrvlic acid 2.3-bis-(4-chloro-benzylidene)-succinic acid n-(4-methyl-3-nitrophenyl)glutaramic acid 3-bromo-5-methoxy-2-propyl-benzoic acid oxamic acid 2-(2-naphthoyl)benzoic acid 2-(2-formamidothiazol-4-yl)-2-methoxyiminoacetic acid (r)-tetrahydrofuran-2-carboxylic acid 4-mercaptobenzoic acid (s)-2-fluoro-2-methylpentanoic acid 4-nitrophenoxyacetic acid ac-d-ala-d-lactic acid 2-(4-hydroxymethyl-3-methoxyphenoxy)butyric acid 4-(3-nitrophenyl)-1,3-butadiene- 1 -carboxylic acid 4-bromo-4,4-difluorobutyric acid 3-(4-chloro-2-nitro-phenyl)-2-oxo-propionic acid 20,20,20-trifluoroarachidonic acid dibromofluoroacetic acid 2-bromolauric acid bis(4-chlorophenoxy)acetic acid 4 4'-trimethylenebis(phenylacetic acid) 4 hydroxy pyridine-3,5-dicarboxylic acid 2-ethoxy-1-naphthoic acid 3-(4,5-diphenyl-2-oxazolyl)propionic acid tetrachlorophthalic acid perchloric acid [3-(methoxycarbonyl)-2-methyl-S5-oxo-2-pyrrolin-4-yl]acetic acid 3-(3-(1-butyrylamino-2.2,2-trichloro-ethyl)-thioureido)-benzoic acid 3,4,9,10-perylenetetracarboxylic acid 3-fluoro-4-hydroxybenzoic acid dl-alpha-hydroxyisovaleric acid 3-(2-chloro-ethanesulfonyl)-propionic acid fmoc-l-pipecolic acid 2-methyl-1,1-dioxo-2,3-dihydro-1h-benzo(b)thiophene-2-carboxylic acid 3-acetyl-thiazolidine-2-carboxylic acid 1-methyl-1-cyclohexanecarboxylic acid 2-(3-benzyloxy-4-methoxy-benzyl)-2-phenyl-malonic acid n-[3-(triethoxysilyl)propyl]phthalamic acid 2.2.5,5-tetramethyl-3-pyrrolin-1-oxyl-3-carboxylic acid fmoc-8-aminocaprylic acid 3-methylthianaphthene-2-acetic acid 3-bromocinnamic acid 1-oxalyl-1.4-phenylenediamine-2-sulfonic acid succinamic acid : 4-[(di-n-propylamino)sulfonyl]benzoic acid alpha-fluorocinnamic acid 2,3-diphenyl-2-cyclopropene- 1-carboxylic acid 3,4-pyridinedicarboxylic acid p-pentyloxybenzoic acid 3-(1,3-dioxo-1h,3h-benzo(de)isoquinolin-2-yl)-benzoic acid
3-tricyclo(8.2.2.2(4,7)hexadeca-hexaen-2-yl-acrylic acid
2-(1-methyl-2-(4-nitro-phenyl)-propoxy)-benzoic acid 2,4 5-trifluorophenylacetic acid 3-chloro-3-p-tolylcarbamoyl-acrylic acid 3,7-dihydroxy-2-naphthoic acid 3-methoxyphenylacetic acid 2-benzoylamino-3-(4-hydroxy-3-methoxy-phenyl)-propionic acid 3-(4-methylbenzoyl)-acrylic acid n-cyclododecyimaleamic acid
11-hydroxyundecanoic acid
3-bromo-2-methylbenzoic acid n-(2,3-dichlorophenyl)maleamic acid 2-fluoro-3-nitrobenzoic acid hydroxy-(2,3,5,6-tetramethyl-phenyl)-acetic acid 2-isopropyl-2-phenylglycolic acid 1-hydroxy-4-(4-nitrophenoxy)-2-naphthoic acid 2-hydroxy-6-(3,4,5-trimethoxyphenyl)-3,5-pyridinedicarboxylic acid (1-amino-1-phosphono-ethyl)-phosphonic acid n-(2,4-dichlorophenyl)maleamic acid n,n'-terephthalylidenebis(4-aminosalicylic acid) trans-aconitic acid
5'-chloro-2'.4'-dimethoxyphthalanilic acid (r)-2-bromobutyric acid 4-azido-2,3,5,6-tetrafluorobenzoic acid n-(3-methoxyphenyltetrachlorophthalamic acid 5-fluoro-2-(triflucromethyl)benzoic acid 2,2-dimethyl-4-pentenoic acid heptadecanoic acid
3,5-pyridinedicarboxylic acid beta,beta-dimethyl-1-pyrrolepropanoic acid 2-chloro-3-(trifluoromethyl)benzoic acid
2,3-dihydro-benzo(b)azepine- 1-carboxylic acid
4-(1-methyl-butyl)-benzoic acid p-(beta-bromoethyl)benzoic acid 2,2-dichloropentanoic acid 7-(dimethylaminosulphonyl)-2,3-dihydro-gamma-oxo-1-(1h)-indolebutanoic acid 13(s)-hydroxyoctadeca-9z,11e-dienoic acid 4-bromophenylacetic acid
(s)-(+)-o-acetylmandelic acid 3-chloro-2-fluorobenzoic acid camphorquinone-10-sulfonic acid
3-nonenoic acid 9-0x0-bicyclo(3.3.1)non-6-ene-3-carboxylic acid 3'-chloro-2.3-dibromo-4'-methylsuccinanilic acid 4-bromo-2-fluorobenzoic acid 17-iodoheptadecanoic acid 1,2,3,4,6,7,8-heptachloro-tricyclo{4.2.0.0(3,8)]oct-4-ene-2,7-dicarboxylic acid n-cbz-l-glutamic acid carboxy phenyl! gama acid 4-benzyloxy-3,5-dimethoxy-benzoic acid 4-cresidine-6-sulfonic acid 2-(2,5-dichlorophenoxy)propionic acid (2-bromo-4.5-dimethoxy-phenyl)-acetic acid 2'-hydroxy-2-biphenylcarboxylic acid
4 4 4-trifluoro-3-(trifluoromethyl)crotonic acid
16-hydroxyhexadecanoic acid 4-nitro-3-(octanoyloxy)-benzoic acid
1,3-diaminopropane-n,n,n’,n'-tetraacetic acid 4-fluoro-2-(trifluoromethyl)cinnamic acid 2,3-dichloroisobutyric acid
3,4-difluorocinnamic acid
3-(3-adamantan-1-yl-ureido)-propionic acid
1,1-dimethyl-indan-4-carboxylic acid d(-)-2-amino-5-phosphonopentanoic acid fmoc-5-aminovaleric acid 3-methoxy-9-0x0-6,7,8,9-tetrahydro-Sh-benzocycloheptene-6-carboxylic acid 4 4-dichloro-4-fluorobutanoic acid (4-(4-carboxymethylsulfanyl-benzyl)-phenylsulfanyl)-acetic acid trans-2-(2-thiophenecarbonyl)-1-cyclohexanecarboxylic acid 3,5-dimethoxy-4-hydroxyphenylacetic acid 1-pyrenebutyric acid n-(2,6-dimethylphenylcarbamoylmethyl)iminodiacetic acid 4-nitrophenyloxamic acid 3-ethyl-cyclohex-4-ene-1,2-dicarboxylic acid (I)-menthyl carboxylic acid 3,3,3-trimethylpyruvic acid 1-methyl-2-phenyl-cyclopent-2-enecarboxylic acid hexahydro-4'-sulfamoyiphthalanilic acid - 2-methoxyphenylacetic acid 3-carboxybenzaldehyde n-phenethylmaleamic acid citrinin 3-nitrophenoxyacetic acid 8-hydroxvoctanoic acid bis-(3-chloro-phenyl)-phosphinic acid 2-(2-carboxy-ethyl)-6,6-dimethyl-3-oxo-cyclohex-1-enecarboxylic acid cis-8-methylnon-6-enoic acid o-(carbomethoxy)-salicylic acid 3-benzoyl-2-(3-chlorophenyl)propionic acid (2-[2-(5-me-[1,3,4]thiadiazol-2-ylsulfanyl)-ac-amino}-thiazol-4-yl)-acetic acid octahydro-3-methyl-1-pentalene carboxylic acid p-phenyl hippuric acid n-(2,2-dichloroacetyl)-5-iodoanthranilic acid
2-fluoro-4-nonyloxybenzoic acid 3,5-dimethyl-p-anisic acid ethylenediaminetetrapropionic acid 2-amino-3,6-dimethyl-5-nitro-benzoic acid 4-(4-methoxybenzoyl)butyric acid methoxyacetic acid 5-benzo(1,3)dioxol-5-y1-8-hydroxy-naphtho(2,3-d)(1,3)dioxole-6-carboxylic acid 4-oxohexanoic acid 2-(p-hydroxybenzoyl)benzoic acid 2-hydroxyeicosanoic acid (r)-3-hydroxy-3-phenylpropanoic acid 4-0x0-6-phenyl-5-hexenoic acid d-desthiobiotin 7-0x0-6-0oxa-bicyclo{3.2.1]octane-3-carboxylic acid 2-hydroxy-3,5-dimethyl-benzoic acid (+)-cis-2-benzamidocyclohexanecarboxylic acid anthracene-1,5-dicarboxylic acid phenyl-n-propylphosphinic acid 3-hydroxyundecanoic acid (2-naphthalen-2-yl-acetylamino)-acetic acid (5-cyano-6-hydroxy-4-methyl-2-oxo-2h-pyridin-1-yl)-acetic acid 2-benzoylamino-3.3-dichloro-acrylic acid 3-methylundecanoic acid 4 4-bis~(3,5-dichloro-4-hydroxyphenyl)-valeric acid fmoc-dl-2-aminohexanoic acid 4-hexenoic acid cyclobutanecarboxylic acid 4.4.5,5,6,6,6-heptafluorohexanoic acid n,n-dimethylsuccinamic acid 2'-carboxysuccinanilic acid 2.5-dimethylbenzenesulfonic acid
4-methyl-4-cyclohexene-1,2-dicarboxylic acid (2-sec-butyl-3-chloro-phenoxy)-acetic acid 3'4'-dichloro-1,2,3,6-tetrahydrophthalanilic acid (r)-(-)-(1-aminoethyl)phosphonic acid (s)-(+)-2-0x0-4-phenyl-3-oxazolidineacetic acid 4-hydroxymethylbenzoic acid 3-hydroxy-4-methoxymandelic acid 3-bromoanisic acid (2-nitro-benzenesulfonyl)-acetic acid 3,3,3-trifluoro-2,2-dihydroxy-propionic acid n-alpha-(benzyloxycarbonyl)-gamma-(t-butyl ester)-d-glutamic acid -(+)-2-amino-5-phosphonovaleric acid 2-fluorobenzoic acid n-(3,3,5-trimethylcyclohexyl)-dithiocarbamic acid
I-(+)-mandelic acid
S-fluoro-2-(trifluoromethyl)cinnamic acid 2,6-dimethylbenzoic acid : (2-chloro-2-phenyl-vinyl)-phosphonic acid 3-benzoyl-2-benzylidenepropionic acid aurintricarboxylic acid 4-(2-naphthyl)butyric acid cis-10-pentadecenoic acid (c15:1) 2-butynoic acid 2,3-dibromo-n-(1-naphthyl)succinamic acid p-chlorophenoxyacetic acid (r)-3-phenylbutyric acid (o-tolyl)phosphonic acid 4'-bromo-3'-methylphthalanilic acid 15-ketoeicosa-6e,8z,11z,13e-tetranoic acid homoisocitric acid para-(4-oxo-2-thioxothiazolidino)-benzoic acid trans-3-acetoxy- 1,3-oxathiolane-2-carboxylic acid 3-formyl-2,4,6-trimethyl-benzoic acid d-3-phenyllactic acid 4'-ethylphthalanilic acid 2-[2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]carbohydrazonoyl}benzoic acid 2'-methylglutaranilic acid 4-nitropicolinic acid 4-chloro-3,5-dinitrobenzenesulfonic acid 2-bromocinnamic acid 3-butoxy-4-nitrobenzoic acid phosphorous acid butylmalonic acid 4-methoxycinnamic acid thiophene-2-acetic acid cycloundecanecarboxylic acid 3'-hydroxyphthalanilic acid (4-tert-butyl-phenoxy)-acetic acid 3-(4-n-pentylbenzoyl)propionic acid 5-(3.5-dichlorophenoxy)furan-2-carboxylic acid 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-methoxybenzoic acid hvdroxy-phenyl-p-tolyl-acetic acid 2-norbornene-2,3-dicarboxylic acid (phenyithio)acetic acid 5-keto-d-gluconic acid 7-ho-1.3-dimethyl-2,4-diox0-1,2,3,4-4h-pyrido(3,2-d)pyrimidine-6-carboxylic acid m-hydroxymandelic acid oxanilic acid alpha-ethylcinnamic acid 3-[5-(4-methoxy-phenyl)-furan-2-yl]-acrylic acid 2.5-dimethoxyphenylacetic acid uvitic acid
2-hydroxyimino-propionic acid
1,2,3-benzenetricarboxylic acid 2.4-dimethylglutaric acid 4-methylcyclohexaneacetic acid 3-(2-chlorophenyl)-2-cyanopropionic acid fmoc-l-norleucine 1,4-benzodioxan-2-carboxylic acid 3-(4-chloro-2-oxo-benzothiazol-3-yl)-propionic acid 4.,5,5,5-tetrafluoro-4-(trifluoromethoxy)pentanoic acid 2.3-dimethylglutaric acid heptafluorobutyric acid 2-benzenesulfonyloxy-3-methoxy-benzoic acid 2'-carboxy-2-hydroxy-4-methoxy-benzophenone 7-methyl-2-phenylimidazo[1,2-ajpyridine-3-carboxylic acid 5-hexenoic acid
3'-chloro-2,3-dibromosuccinanilic acid oe 2.2-dichlorohexanoic acid 4-((pyridine-4-carbonyl)-amino)-butyric acid 3,3-dichloropivalic acid 2-imidazolidone-4-carboxylic acid beta-oxalylamino-d-alanine 4'-ethoxy-3,4,5.6-tetrachlorophthalanilic acid (2-benzothiazolylthio)acetic acid 4-benzyloxyindole-2-carboxylic acid 2-trans-benzoyl-5-trans-phenyl-1-cyclohexanecarboxylic acid 12-nitro-tricyclo(8.2.2.2(4,7))hexadeca-hexaene-S-carboxylic acid 2-acetyl-3-thiophenecarboxylic acid 4'-nitrosuccinanilic acid 2-hydroxyisobutyric acid 2,3-dimethylbenzoic acid propylene diphosphonic acid
2-cyclopentene-1-acetic acid
4-(pyridin-2-yl-acetyl)-benzoic acid 4-(3-(3-chioro-4-fluorophenyl)ureido)benzoic acid 4-nitrophenylglyoxylic acid pth-glutamic acid (8r,15s)-dihydroxy-(5z,9¢,11z,13e)-eicosatetraenoic acid 5-nitro-2-furoic acid
2-butyloctanoic acid n-formyl-4-nitroanthranilic acid 2-methoxy-alpha-methylcinnamic acid 2-(2-ethoxycarbonyl-acetylamino)-benzoic acid 2,3-dimethylphenoxyacetic acid 3.5-dimethoxy-4-hydroxycinnamic acid 3-chloro-4-nitrobenzenesulfonic acid dl-alpha-aminopimelic acid alpha-cyano-4-hydroxycinnamic acid 3-((5-bromo-1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-amino)-benzoic acid n-ethyl-l-aspartic acid n-alpha-fmoc-n-beta-boc-d-diaminopropionic acid n-t-boc-(2s,3r)-3-amino-2-hydroxy-4-(4-nitrophenyl)butyric acid 2.6-pyridinedicarboxylic acid 3-dibenzo(a,c)phenazin-11-yl-acrylic acid valerenic acid nicotinic acid n-oxide 5-(4-benzyloxy-3-methoxy-phenyl)-penta-2,4-dienoic acid 4-chlorophenyl cyclohexane carboxylic acid 4-(p-chlorophenoxy)butyric acid n-tris[hydroxymethyl]methyl-4-aminobutanesulfonic acid s-4-nitromandelic acid
4,5-dichloro-2-fluorobenzoic acid n-(2,3-xylyl)glutaramic acid
4,5,5-trifluoro-4-pentenoic acid 5-fluoro-2,6-dihydroxy-pyrimidine-4-carboxylic acid 3-phenylsalicylic acid 2-(2-hydroxy-5-methyl-benzoyl)-benzoic acid cis-4-cyclohexene-1,2-dicarboxylic acid 2-bromostearic acid l-trans-pyrrolidine-2,4-dicarboxylic acid 2-chlorobenzoic acid 5-sulfonic acid 3-thiophenecarboxylic acid 2-((3-methoxy-phenyl)-phenyl-methylene)-succinic acid 3-chlorocinnamic acid 4-phenylcinnamic acid 3-(3,5-dinitro-4-hydroxyphenyl)propionic acid 7-acetoxycoumarin-3-carboxylic acid d-alpha-galacturonic acid 3-bromo-2,5,6-trimethoxybenzoic acid 3-tert-butyl adipic acid 2-methylnonanoic acid 3-hydroxy-4-methyl-2-nitrobenzoic acid 2,6-dihydroxy-4-methyl-benzoic acid 7-(3.3-dimethyl-2.3-dihydro-benzofuran-3-vl)-3-methyl-octa-2 4 6-trienoic acid 5-methoxy-2-propyl-isophthalic acid 3-(3-benzyloxy-4,5-dimethoxy-phenyl)-propionic acid (1s,2s)-(+)-1,2-cyclohexanedicarboxylic acid 2-(amidinothio)ethanesulfonic acid d-(-)-s-benzoyl-b-mercaptoisobutyric acid 3-fluoro-5-(triflucromethyl)benzoic acid 2-(9h-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butyric acid 2-bromo-4-nitro-benzoic acid (s)-2-ethyldecanoic acid 11-phenoxyundecanoic acid
2-nitro-6-(2,4-pentadien- 1-yloxy)benzoic acid 5-(methanesulphonyl)thiophene-2-carboxylic acid : 2-(4-fluorobenzoyl)benzoic acid 2-benzoyl-3,6-dimethylbenzoic acid 2-carboethoxysyringic acid 3.3',4,4',5,6-hexachlorophthalanilic acid 3-methylthiopropionic acid (+/-)-abscisic acid 4-chloro-3-nitrophenylacetic acid 2-octynoic acid 3-(4-azidophenyl)propionic acid 9,10-dihydro-9,10-ethanoanthracene-11-carboxylic acid (2-hydroxyimino-propionylamino)-acetic acid n-(4-ethoxycarbonylphenyl)phthalamic acid dl-2-amino-3-phosphonopropionic acid 2-(2-dibenzo(a,d)cyclohepten-5-ylidene-ethyl)-malonic acid 7-phenylheptanoic acid 5-bromo-4,4,5 5-tetrafluoropentanoic acid 8-benzoyloctanoic acid 3-hydroxy-5-(1-hydroxy-1-methyl-ethyl)-cyclohexanecarboxylic acid 3-dodecenoic acid n-(1-naphthyl)-3.4,5,6-tetrachlorophthalamic acid 4-(trifluoromethyl)phenylacetic acid s-acetamidomethyl-3-mercaptopropionic acid dihydroanthracene-9,10-dicarboxylic acid meso-2,5-dibromoadipic acid 2,3-dibromo-2'-methoxy-5'-methylsuccinanilic acid 3-chloro-4-(isopropylsulphonyl)-5-(methylthio)thiophene-2-ca rboxylic acid 4-n-propylbenzoic acid 2,3-dibromo-3-(2-(methoxycarbonyl)phenylcarbamoyl)propionic acid 10-heptadecenoic acid
3-methoxyphenoxyacetic acid 4,4'-dimethylenebis(phenylacetic acid) 4-chloro-3,5-dinitrobenzoic acid : diethylphosphonoacetic acid : (1r)-(-)~(1-aminopropyl)phosphonic acid
Ln = (r)-3-(4-fluorophenyl)butanoic acid phenazine-1,6-dicarboxylic acid [1r-(ex0,ex0)]}-3-(benzoyloxy)-8-azabicyclo[3.2.1]octane-2beta-c arboxylic acid 2'-fluorophthalanilic acid 4-bromo-3-methylbenzoic acid 3-(morpholine-4-carbothioylsulfanyl)-propionic acid (6-iodo-benzo(1,3)dioxol-5-yl)-acetic acid 3'-fluorohexahydrophthalanilic acid 1-phenylsulfonyl-4,4-piperidinedicarboxylic acid i. 2-(3,5-xylyl)acetic acid beta-chlorolactic acid 10,12-heptacosadiynoic acid n-acetyl-1-thiazolidine-4-carboxylic acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid trans- 1 S-octadecenoic acid 2'-(hydroxymethyl)-2-biphenylcarboxylic acid coumalic acid n-(2,4,6-trimethylphenylcarbamoylmethyl)iminodiacetic acid 2-(3,4-dimethoxy-phenyl)-3-(2-nitro-phenyl)-acrylic acid suberic acid heptadecanedioic acid 2'.4' 6'-trimethylmaleanilic acid uramil-n,n-diacetic acid (2,3-xylylphosphonic acid 6-chlorokynurenic acid 8-i0do-1-naphthoic acid
4-(1,1,2,2-tetrafluoroethoxy)benzoic acid
3-(n-(4-methylphenyl)carbamoyl)-5-norbornene-2-carboxylic acid elaidic acid n,n,n',n'-1,4-phenylenediaminetetraacetic acid 3-(3,4-dichlorobenzoyl)-2-(4-methylphenyl)propionic acid 3-phenyl-pyrrolo(2,1,5-cd)indolizine-1,2-dicarboxylic acid phenylglycine-o-carboxylic acid
2 4-dimethyl-6-(2'-methylpropyl)benzene-1,2'-dicarboxylic acid 4-benzoylbutyric acid n-alpha-n-beta-di-z-1-diaminopropionic acid 4-((6-phenyl)-1,3,5-hexatrienyl)benzoic acid 4-(2-chloroethyl)benzoic acid
(2,2-difluoro-adamantan- 1-vl)-acetic acid trans-2-octenoic acid cis,cis-2,5-dimethylmuconic acid 4-(fluorosulfonyl)benzoic acid 2-{[(4-chlorophenyl)sulfonyl](2-pyridyl)amino]acetic acid beta-n-oxalylamino-l-alanine octanoic acid
1-dihydroorotic acid
14-hydroxy-10.12-tetradecadiynoic acid 4-(2,5-dimethylphenyl)butyric acid 2,2-difluoro-2-phenoxyacetic acid n-[3-(trifluoromethyl)phenyljmaleamic acid n-carbamyl-dl-alpha-amino-n-butyric acid 1-(m-sulfophenyl)-3-methyl-5-pyrazolone acenaphthen-5-yl-acetic acid cis-15-octadecenoic acid benzo(c)phenanthrene-6-carboxylic acid 2-chloro-5-iodobenzoic acid
1-(4-fluorophenyl)cyclopentanecarboxylic acid
3-heptenoic acid chromone-3-carboxylic acid (s)-(-)-2-chloropentanoic acid 3-(2,5-dimethyl-phenyl)-3-methyi-butyric acid (s)-(+)-2-bromo 3-phenylpropionic acid cyclohexylphenylacetic acid 3,3',3"-nitrilotripropionic acid 2-biphenylcarboxylic acid - (4-chloro-3,5-dimethyl-phenoxy)-acetic acid 4-(2-amino-5-bromo-3-ethyl-phenyl)-4-oxo-butyric acid 3,4-methylenedioxycinnamic acid oe 5-(2-nitrophenyl)-2-furoic acid = 4'-bromo-3'-methyvlsuccinanilic acid 2,3-dihydrobenzofuran-7-carboxylic acid
Sh. o 4-(2,4-di-tert-pentyl-phenoxy)-butyric acid 4-(3,4-dimethoxyphenyl)butyric acid
Es 2-[(5-chloro-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid : 9-anthracenecarboxylic acid (r)-3-(4-tert-butoxyphenyl)butanoic acid 5,5'-methylenedisalicylic acid 4-methylnonanoic acid 2-fluoro-6-iodobenzoic acid
I-(+)-s-acetyl-beta-mercaptoisobutyric acid 1(+)-2-(2,4-dichlorophenoxy) propionic acid (+/-)5,6-epoxyeicosa-8z,1 1z,14z-trienoic acid 1,6-naphthalenedicarboxylic acid 3-1sobutyrylamino-3-phenyl-propionic acid (z)-(3)-10doacrylic acid 1-(4'-sulfophenyl)-3-carboxy-5 -pyrazolone 4-(3-phenyl-2-thioureido)hippuric acid 4-(2-(2-hydroxy-phenoxy)-acetylamino)-benzoic acid
1-ethyl-4-0xo0-1,4-dihydro-quinoline-3-carboxylic acid 6-(trifluoromethyl)nicotinic acid
S-norbornene-2-endo,3-exo-dicarboxylic acid 4'-bromo-2'-chlorosuccinanilic acid 2-acetoxy-3-methylbenzoic acid 4-chloro-3-nitrocinnamic acid 2-(benzenesulphonyl)ethylthio acetic acid 1 1-(methoxycarbonyimethylthio)-undecanoic acid cis-3',5'-dimethylhexahydrophthalanilic acid 2,6-dichloro phenoxy acetic acid 3-chloro-4-hydroxyphenylacetic acid 7-[{(4-amino-3-sulfophenyl)amino]-4-hydroxy-2-naphthalenesulfonic acid n-alpha-(benzyloxycarbonyl)-alpha-(t-butyl ester)-l-glutamic acid 6-ketoundecane-1,11-dioic acid 6-amino-2-(2-ho-et)-1,3-dioxo-2.3-2h-1h-benzo(de)isoquinoline-5-sulfonic acid 3-nitrophenylacetic acid 5-methyl-2-thiophenecarboxylic acid 2-[3-(n'-dodecanoyl-hydrazino)-3-oxo-propionylamino}-benzoic acid 4'-nitrophthalanilic acid 3-nitro-4-phenoxybenzenesulfonic acid 1.2.3,4-butanetetracarboxylic acid (1s)-(+)-(1-aminohexyl)phosphonic acid (s)-3-phenylbutyric acid diethylenetriaminepentaacetic acid boc-d-2-aminobutyric acid 3-bromo-4-chloropentafluorobutyric acid 2.4,6-trinitrobenzoic acid 2-nitrophenoxyacetic acid dl-homocysteic acid (4-ethylphenyl)phosphonic acid 4-(4-nitrophenyl)butyric acid
~ cis-cyclobutane-1,2-dicarboxylic acid thieno(3,2-b)thiophene-2-carboxylic acid meso-butane-1,2,3,4-tetracarboxylic acid pentafluorobenzene sulfonic acid a : o-iodohippuric acid : 4,5,6,7-tetrafluoro-3-indoleacetic acid 2-(phenethylthio)-acetic acid 1-hydroxyethane-1.1-diphosphonic acid 1-2-aminoadipic acid 6-oxoheptanoic acid 2-formamido-3-thiophenecarboxylic acid : 14-methylpentadecanoic acid bis-(4-bromo-phenyl)-hydroxy-acetic acid 3-iodopropionic acid 2,6-dioxo-4-piperidinecarboxylic acid . d-alpha-aminoadipic acid “ 3-bromo-5-chloro-2,6-dimethoxy benzoic acid orotic acid 6-[2-acetylamino-3-(4-methoxy-phenyl)-acryloylamino}-hexanoic acid 3-(4-chlorobenzenesulphonyl) butyric acid 2-bromoisophthalic acid 3-amino-4-isopropenyl-benzoic acid 3-phenoxypropionic acid n-(2-chlorophenyl)glutaramic acid 4-[(e)-2-(5,6,7,8-tetrahydro-5,5,8.8-tetramethyl-2-naphthalenyl)- 1-propenyl] benzoic acid 3-chloro-2-methylbenzoic acid 3-(3-ethoxyphenyl)propionic acid 2'-chloro-6'-methylphthalanilic acid 4-[[2-fluoro-5-(methylsulphonyl)phenyljamino]-4-oxobutanoic acid 3,6-dimethylsalicylic acid 3-(2,6-dichlorobenzylthio)-2-thiophenecarboxylic acid
(s)~(-)-2-guanidinoglutaric acid
3,4-dinitrobenzoic acid alpha-trityl-2-naphthalenepropionic acid 3,4-dichlorophenylacetic acid phenylbenzene omega-phosphono-alpha-amino acid n-methylhippuric acid hydroquinone-o,0-diacetic acid
3-~(4-n-octylbenzoyl)propionic acid
1 1-methyltridecanoic acid
3-~cyclohexylpropionic acid
3,5-di-tert-butyl-4-hydroxybenzoic acid (3-cyano-6-(4-methoxy-phenyl)-3-methyl-2-oxo-cyclohexyl)-acetic acid 4-hydroxyisophthalic acid di(cyclohexyl) phosphoric acid
3-aminoadipic acid
(4-nitrobenzyl)phosphonic acid 4-(4-methoxy-phenyl)-4-methyl-pentanoic acid 4-(2-hydroxybenzylideneamino)salicylic acid n-hexadecylphosphonic acid
4'-methoxyphthalanilic acid
1-ho-8-imino-3-0x0-4-(4-sulfo-phenylamino)-5,8-2h-naphthalene-2-sulfonic acid kainic acid tetrahydrofuran-2,3,4,5-tetracarboxylic acid
4-methyl-5-oxohexanoic acid
12-0x0-12-(1-pyrenyl)dodecanoic acid alpha-isoatropic acid
4-(2-thienylmethyleneamino)salicylic acid
1odic acid
2-fluorophenylacetic acid
(benzoyl-benzyl-amino)-acetic acid cis-3-chloroacrylic acid
3-pyrimidin-2-yl-propionic acid 2-(2-(3,4-dimethyl-phenoxy)-acetylamino)-benzoic acid malonamic acid (s)-(+)-(1-aminoethyl)phosphonic acid 6-methyl-2-pyridin-4-yl-quinoline-4-carboxylic acid 4,6-dimethyl-isophthalic acid di-n-propylphosphate benzothiazol-2-yl-2-(2-aminothiazole-4-yl) acetic acid 5-(4-fluorobenzoyl)thiophene-2-acetic acid 2-acetylamino-but-2-enoic acid 4-fluoro-2-(trifluoromethyl)benzoic acid 8,11-eicosadiynoic acid n-(4-methylphenyl)tetrachlorophthalamic acid 4'-butylhexahydrophthalanilic acid : ethylxanthogenacetic acid alpha-phenylcyclopentaneacetic acid n-methyl-l-aspartic acid 3-bromo-5-methoxy-2-methyl-benzoic acid iso octyl phosphate acid 2-(2,2-dimethyl-propionylamino)-4,5,6,7-4h-benzo{b]thiophene-3-carboxylic acid 4-chloro-3-nitrobenzoylbenzoic acid n-(2-carboxyphenyl)malonamic acid 2,5-norbornadiene-2,3-dicarboxylic acid 3-benzyloxy-4,5-dimethoxy-benzoic acid 4-(2-isopropylisulfanyl-acetylamino)-benzoic acid 5-fluoro-6-hydroxy-pyrimidine-4-carboxylic acid 2-(3-nitro-benzylidene)-pent-4-enoic acid n-carbamoylmaleamic acid 4-(4-hydroxyphenoxy)benzoic acid tetracosanedioic acid 2-bromo-5-methoxybenzoic acid
4-formylcinnamic acid (methylthio)acetic acid 4-0x0-4-(4-(4-(ethoxycarbonyl)butyl)phenyl)butyric acid 2,4-dichlorophenoxyacetic acid 4-((1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-amino)-benzoic acid 3,4-dimethoxyphenylpyruvic acid (s)-2-fluoro-2-methylheptanoic acid 2-benzoylamino-3-(4-benzyloxy-3-methoxy-phenyl)-acrylic acid 3-naphthalen-1-yl-propynoic acid 4 4-dinitroheptanedioic acid 3-benzo(1,3)dioxol-5-yl-propynoic acid tetraacetyl-mucic acid cis-hexahydro-n-(4-ethoxyphenyl)phthalamic acid 3-[(3,5-dimethoxy-phenyl)-(toluene-4-sulfonyl)-amino]-propionic acid 3-(4-n-pentyloxybenzoyl)propionic acid 2-chlorocinnamic acid n-cyclohexylglutaramic acid (-)-cis-2-benzamidocyclohexanecarboxylic acid - dl-citramalic acid 1h-pyrazole-3,4-dicarboxylic acid 2-fluoro-4-hexyloxybenzoic acid n-(3-chloro-2-methylphenyl)glutaramic acid trans-1.2-diaminocyclohexane-n,n,n',n'-tetraacetic acid monohydrate 2.2-dichlorooctadecanoic acid 2-fluoro-6-(trifluoromethyl)cinnamic acid boc-d-7-hydroxy-1,2,3 4-tetrahydroisoquinoline-3-carboxylic acid 5-(3-methoxy-phenyl)-hexa-2,4-dienoic acid 5-(4-hydroxy-3-methoxy-phenyl)-pentanoic acid 5-(alpha,alpha-dimethyl-4-hydroxybenzyl)salicylic acid 3-decenoic acid n-benzyliminodiacetic acid n-alpha-(benzyloxycarbonyl)-l-glycyl-l-glycine (4-ethoxyphenyl)phenylphosphinic acid : (4'-carboxymethylsulfanyl-biphenyl-4-ylsulfanyl)-acetic acid 1-methylorotic acid 3-(3,5-di-tert-butyl-benzoylamino)-benzoic acid 4-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-benzoic acid oo 2' 5'-dimethoxymaleanilic acid boc-alpha-aminobutyric acid (3-nitro-phenyl)-phosphonic acid : 4-(2-acetylamino-3-phenyl-acryloylamino)-butyric acid : 2.2-bis-(4-chlorophenyl)-acetic acid }-alpha-glutamyl-l-alpha-glutamyl-l-glutamic acid 4-(trifluoromethoxy)phenoxyacetic acid 2-ene-valproic acid n(o-tolyl)phthalimidic acid n-(2-ethylphenyl)glutaramic acid 2.4,6-trihydroxybenzoic acid cis-2-hydroxy-1-cyclopentanecarboxylic acid diphenylphosphinic acid 4-(4-methoxyphenyl)thiophene-2-carboxylic acid 4-(4-methylbenzylideneamino)salicylic acid (2.2,2-trichloro-1-(3-p-tolyl-thioureido)-ethyl)-carbamic acid (s)-(+)-alpha-hydroxy-1,3-dioxo-2-isoindolinebutyric acid 2,2'-(1,2-ethanediyl)bis[5-aminobenzenesulfonic acid) 4'-nitromaleanilic acid 3,5-diisopropoxybenzoic acid n-(4-(4-chloro-phenoxy)-phenyl)-phthalamic acid benzoylamino-phenyl-acetic acid 4-chloro-3-nitrobenzoic acid 4-methylphthalic acid beta-(2-acetoxyphenyl)propionic acid
(3-fluorophenyl)phosphonic acid (r,1)-(-)-2,3-diphenylsuccinic acid 2-(4-chlorophenyl)-1-(2-(34dimethoxyphenyl)ethyl)6oxo3piperidinecarboxylic acid ethoxyacetic acid 3-(3-(2,4,5-trichlorophenyl)ureido)benzoic acid 2-[3-0x0-3-(n'-tetradecanoyl-hydrazino)-propionylamino}-benzoic acid 2-(2-(2-chlorophenyl)-4-phenylthiazol-5-yl)acetic acid 4-(benzylideneamino)benzoic acid heneicosanoic acid cis-hexahydro-n-(3-nitrophenyl)phthalamic acid 3-(n-cyclohexylcarbamoyl)-5-norbornene-2-carboxylic acid cyclohexanecarboxylic acid 3-(2-hydroxypheny!)propionic acid 3'-fluoroglutaranilic acid tetrafluoroterephthalic acid 4-acetamido-3-fluorobenzoic acid dihydroxyfumaric acid 4-butoxyphenylacetic acid dl-beta-hydroxypalmitic acid 13-keto-octadeca-9z, 11e-dienoic acid 1-propionyl-pyrrolidine-2-carboxylic acid 3',5'-dichloro-2'-hydroxy-4'-methylmaleantlic acid 3-(triphenylsilyl)propionic acid 2-methyl-2-pentenoic acid (3-chlorophenyl)phosphonic acid 3-(thiophen-3-ylsulfanyl)-thiophene-2-carboxylic acid 3-fluoro-4-methoxybenzoic acid 3-(4-biphenylyloxy)propionic acid boc-gamma-aminobutyric acid 4,5-dimethoxy-2-nitrophenylacetic acid 3-(2,4-dihydroxyphenyl)propionic acid
2-hexadecylcarbamoyl-4-nitrobenzoic acid 3-fluoro-4-hydroxyphenylacetic acid : 4-(trifluoromethoxy)phenylacetic acid benzoylformic acid camphoric acid 5-benzo(1,3)dioxol-5-yl-penta-2,4-dienoic acid 2.3 4-trimethoxyphenylacetic acid 2-(3,5-dinitro-thiophen-2-ylamino)-3-methyl-butyric acid : 3-(4-methoxy-phenyl)-2-(1-phenyl-ethylideneamino)-acrylic acid l-ascorbic acid methylsuccinic acid . (-)-isoborneol-3-acetic acid 1,1.2-cvclopropanetricarboxylic acid indole-6-carboxylic acid 4-(hexadecylthio)benzenesulfonic acid > hexahydro-n-(2,3-xylyl)phthalamic acid :
Fi (r)-(+)-n-(1-phenylethyl)succinamic acid 2,6-naphthalenedicarboxylic acid : 5-chloro-2-iodobenzoic acid 2-(4-bromobenzoyl)-acrylic acid 2-fluoro-3-(trifluoromethyl)cinnamic acid 8,8'-diapocarotenedioic acid 5,6-dichlorovanillic acid 3-hydroxytridecanoic acid 2-([2-[3-chloro-5-(trifluoromethyl)-2-pyridyljhydrazinojcarbonyl)benzoic acid 2-methoxy-9-o0x0-8,9-dihydro-7h-benzocycloheptene-6-carboxylic acid cis-5.8,1 1 -eicosatrienoic acid 3-hydroxybutyric acid 2-nitro-4-(trifluoromethyl)phenylthioglycollic acid 2,4-bis(trifluoromethyl)phenylacetic acid 4-hydroxy-alpha-mercapto-3-methoxycinnamic acid
4-chloro-nitrobenzene sulfonic acid 4-methylumbelliferyl phosphate 2' 5'-dimethylphthalanilic acid 3-(naphthalene-2-sulfonyl)-propionic acid 2',6'-diisopropylglutaranilic acid 2-(3,4-dimethoxystyryl)glyoxylic acid 6-(4-(3-carboxy-propyl)-phenyl)-hexanoic acid metatartaric acid dodecafluorosuberic acid phenol sulphonic acid 5-bromo-2,4-dihydroxybenzoic acid 2-(9h-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid 4-butyloxybiphenyi-4'-carboxylic acid p-phenylazobenzenesulfonic acid 4-methylsulphonylphenylacetic acid 3-benzyloxy-4-methoxy-2-nitro-benzoic acid 4 5-dihydro-4,5-dioxo-1h-pyrrolo[2,3-flquinoline-2.7 9-tricarboxylic acid 2'-(trifluoromethyl)maleanilic acid 2-benzoylbenzoic acid 4-chloro-2-(2-thienylethyl)benzoic acid r-(-)-hexahydromandelic acid 2.5-dichloro-4-methoxy-benzoic acid benzyloxycarbonyl-d-pyroglutamic acid n-(2-cyanoacetamido)-3,4,5,6-tetrachlorophthalamic acid (r,s)-fmoc-1,3-dihydro-2h-isoindole carboxylic acid cis- 1-amino-3-(2-phosphonoacetyl)cyclobutane- 1 -carboxylic acid alpha-(2,4-dimethoxy-3-methylbenzylidene)hippuric acid 5-fluoro-2-methylbenzoic acid 1,3,3a,4,7,7a~hexahydro-2-methyl-3-phenyl- 1-oxo-3a-isoindolecarboxylic acid 5(s),12(s)-dihydroxyeicosa-6¢,8z,10e,14z-tetraenoic acid 5(s), 14(r), 15(s)-trihydroxyicosa-6-trans-8-cis-10-trans- 12-trans-tetraeno ic acid
4-(3-[2,2.2-tri-cl-1-(cyclopentanecarbonyl-amino)-et]-thioureido)-benzoic acid dodeceny! succinic acid blend : alpha-fluorophenylacetic acid (4-amino-3-(3-chloro-phenyl)-pyrimidin-2-ylsulfanyl)-acetic acid : 3-(3,4,5-trimethoxyphenyl)-2-thiopyruvic acid n-fmoc-(3s,4s)-4-amino-3-hydroxy-5-cyclohexylpentanoic acid n-acetyl-dl-glutamic acid 2-(hexadecyloxy)benzoic acid . 3-(2,2-dimethyl-propionylamino)-3-phenyl-propionic acid 4-(4'-n-heptylphenyl)benzoic acid 3-(4-n-hexyloxybenzoyl)propionic acid (+/-)-1-amino-cis-3-phosphonocyclopentanecarboxylic acid dl-pyroglutamic acid 4-(2-carboxy-acetylamino)-benzoic acid 8,11,14-eicosatriynoic acid
E 2,2-bis(hydroxymethyl)butyric acid 1,10-phenanthroline-2,9-dicarboxylic acid 2-carboxymethoxy-3-methoxy-benzoic acid (s)-(+)-2,2-dimethyl-5-o0x0-1,3-dioxolane-4-acetic acid 1,2-diphenyl-cyclopropanecarboxylic acid d-glutamic acid (4-isopropyl-2-methoxy-phenoxy)-acetic acid (4-dimethylamino-6-methyl-pyrimidin-2-ylsulfanyl)-acetic acid dl-glyceric acid l-beta-p-nitrophenyllactic acid 5-bromo-6-hydroxy-pyrimidine-4-carboxylic acid 2-(2-chlorophenyl)-4-methylthiazole-5-carboxylic acid 2-benzamido-3-methylcrotonic acid 2-amino-4-trifluoromethylthiazole-5-carboxylic acid 4,5,10,11-tetramethyl-tetradeca-2,4,10,12-tetracne-6,8-diynedioic acid 3-hydroxy-4,4,4-trifluorobutyric acid
4'-fluoro-3'-nitroglutaranilic acid (3,5-dimethoxyphenyl)acetic acid 4-phenylphthalic acid 2'-chloro-hexahydro-5'-(trifluoromethyl)phthalanilic acid n-(4,6-dimethylpyrimidin-2-yl)-3-aminobenzoic acid 4-(hexadecyloxy)-3-nitrobenzenesulfonic acid (r)-(+)-2-bromopentanoic acid s-trans,trans-farnesylthiosalicylic acid (4-(5,5-dimethyl-hexyl)-phenoxy)-acetic acid 4-(2,4,5-trichlorophenoxy)-butyric acid (+/-) 12-hydroxyeicosa-5z,8z,10¢,14z-tetraenoic acid 4-(octadecyloxy)benzoic acid 4'-fluoro-3'-nitrohexahydrophthalanilic acid 4-bromophthalic acid hydantoin-5-acetic acid n-tert-butylphthalamic acid d-(-)-o-formyloxy-2-phenylacetic acid 2.3-dichloropropionic acid 2-dodecenedioic acid iso-butylacrylic acid 3-(4-fluorothiophenoxy)propionic acid 4-(2-benzoylacetamido)benzoic acid 4-0x0-4-phenylamino-2-butenoic acid 4-oxo0-hepta-2,5-dienedioic acid acetodiphosphonic acid 3,5,5-trimethylhexanoic acid 3-ethyl-2-hexenoic acid 3'-chloro-2'-methyl-1,2,3,6-tetrahydrophthalanilic acid 3,4-diacetoxyphenylacetic acid trans-1,4-cyclohexanedicarboxylic acid 3-(3-hydroxy-phenyl)-2-methyl-acrylic acid boc-l-4-thiazolylalanine n-(5-chloro-2,4-dimethoxyphenyl)glutaramic acid 16-methyloctadecanoic acid 4-n-hexyloxybenzoic acid
: 3-(n-(3,4-dimethylphenyl)carbamoyl)-5-norbornene-2-carboxylic acid
2-dodecanoylamino-benzoic acid 2-isopropoxybenzoic acid 3-(2-carboxy-ethyl)-6-chloro-1h-indole-2-carboxylic acid
; beta-phenylcinnamic acid
3-(n-(4-chlorophenyl)carbamoyl)-5-norbomene-2-carboxylic acid 2-(3,4-dimethoxy-phenyl)-3-phenyl-acrylic acid 1,2,3,4-tetrahydro-2-naphthalenepropionic acid 3-(3,5-dimethoxy-4-hydroxyphenyl)-propionic acid 3-bromo-4-methoxyphenylacetic acid 1-acetoxy-2-naphthoic acid - 4-hydroxy-3-(p-diazophenylphosphorylcholine)-phenylacetic acid 6-nitrocaproic acid : 3-nitro-4-(4-chlorophenoxy)cinnamic acid octadec-9-ynedioic acid n(2-chlorophenyl)malonamic acid 4'-ethoxyglutaranilic acid 2,4,6-trihydroxybenzoic acid n-fmoc-l-homophenylalanine n-(4-acetamido-3-methoxyphenyl)phthalamic acid n-(4-piperidone)glutaramic acid 4-(1 -(n-(2-chloro-5-nitrophenyl)carbamoyl)-3,3-dimethyl-2-oxobutoxy)benzoic acid 1-naphthoxyacetic acid benzyloxycarbonyl-l-pyroglutamic acid 2-chloroisophthalic acid 2-amino-3-bromo-5-iodobenzoic acid 2,4, 6-trifluorophenylacetic acid fmoc-(3s,4s)-4-amino-5-cyclohexyi-3-hydroxypentanoic acid 3,3'4,5,5' 6-hexachlorophthalanilic acid 2.4.5-trifluorocinnamic acid 2-bromo-5-fluorocinnamic acid 3-hydroxy-alpha-mercapto-beta-methylcinnamic acid 3-benzoyl-2-(4-chlorophenyl)propionic acid
I-homocysteic acid 4-(3-(2,6-xylylureitdo)benzoic acid n-4-tert-butylbenzoyl-n-phenylanthranilic acid benzothiazole-2-sulfonic acid 4-methyl-dec-4-en-8-ynoic acid 4-methoxy-3-nitrobenzoic acid 4-(3-(5-chloro-2-methoxyphenyl)ureido)benzoic acid 3-bromo-2-methylacrylic acid d-campholic acid fmoc-(3s.4s)-4-amino-3-hydroxy-6-methylthio-hexanoic acid 10,12-heptadecadiynoic acid 4-(((4-chloro-benzenesulfonylimino)-phenyl-methyl)-amino)-benzoic acid 13-cis-retinoic acid 2-(carboxymethoxy)benzoic acid cis-hexahydro-n-(4-methyl-3-nitrophenyl)phthalamic acid 6-hydroxy-5-nitroso-2-naphthalenesulfonic acid 3-chlorothiophene-2-carboxylic acid 3-benzyladipic acid 2' 5'-dimethylsuccinanilic acid bis(2-ethylhexyl) pyrophosphoric acid 4-oxo0-3-phenyl-2-thioxo-1-imidazolidineacetic acid (11, 2s)-1-hydroxy-1,2,3,4-tetrahydro-2-naphthoic acid 5-(4-fluorophenyl)-2,3-dihydro- 1h-pyrrolizine-6,7-dicarboxylic acid 3-(n'-(2,4-dinitro-phenyl)-hydrazinocarbonyl)-acrylic acid n-chloroacetyl-dl-alpha-amino-butyric acid
2-(2-hydroxy-benzoyl)-benzoic acid 3-benzoylamino-3-phenyl-propionic acid 4-heptyloxybiphenyl-4'-carboxylic acid 4-nitrohippuric acid : 4'-jodosuccinanilic acid 2-acetamidoisophthalic acid 15-phenyl-3-methyl-pentadecanoic acid trans-4-propylcyclo hexanecarboxylic acid dibutyl phosphate 4' 4"-sulfonyldimaleanilic acid trans, trans-muconic acid 2-(3 4-dimethoxyphenylthio)acetic acid : 4-((5-bromo-2-hydroxy-benzylidene)-amino)-benzoic acid (s)-(+)-3-(benzyloxycarbonyl)-5-o0x0-4-oxazolidineacetic acid fmoc-(3s,4s)-4-amino-3-hydroxy-6-methylheptanoic acid 3-(n-benzylcarbamoyl)-5-norbornene-2-carboxylic acid (s)-(+)-2-(benzyloxycarbonyl)-1 2.3 4-tetrahydro-3-isoquinolinecarboxylic acid (2-phenoxyethylthio)acetic acid 1-nitroanthraquinone-2-carboxylic acid d-homocysteinesulfinic acid 3-methoxybutyric acid 2-iodobenzoic acid alpha,3-dibromo-1-adamantaneacetic acid 4-(2-hydroxyethoxy)benzoic acid 4-benzenesulfonyl-4-cyano-heptanedioic acid n-phthalyl-dl-aspartic acid 2-(1-cyclohexenyl)-butyric acid 3-(4-chlorobenzyloxy)thiophene-2-carboxylic acid 4-(2-hydroxy-ethylamino)-3-nitro-benzoic acid 2,3-dichloro-6-fluorobenzoic acid 6-(2-carboxy-ethyl)-2,3-dimethoxy-benzoic acid
4.5-dibromo-2-fluorobenzoic acid ethylchromotropic acid 4-butylbenzoic acid edta, isothiocyanobenzyl- 5,6-diamino-1,3-naphthalenedisulfonic acid 11-(butyithio)-undecanoic acid 3-(2-ethylsulfanyl-benzothiazol-6-ylcarbamoyl)-acrylic acid
S-nitrobenzofuran-2-carboxylic acid (ethylenedithio)diacetic acid o-isopropy! benzoic acid 3-(3-(4-acetoxy-phenyl)-2-benzoylamino-acryloylamino)-propionic acid 2.3.5,6-tetramethyl-benzoic acid 3.4-methylenedioxyphenylacetic acid 2-hydroxyamino-3-methyl-butyric acid trans, trans-2,4-hexadienoic acid 3-(trifluoromethyl)benzoic acid 1-naphthylamine-3,5,7-trisulphonic acid 4-aminophenylsuccinic acid 3-[benzyl-(toluene-4-sulfonyl)-amino]-propionic acid 11-methyldodecanoic acid 3.5-difluoromandelic acid 2'.4' 5'-trichlorosuccinanilic acid (+/-)-jasmonic acid (+/-)-2-(6-methoxy-2-naphthyl)propionic acid nitrilotriacetic acid 2-methoxy-3-methylbenzoic acid 2-(4-chloro-benzoylamino)-3-hydroxy-propionic acid 3-benzoyl-2-naphthoic acid 4'-(trifluoromethyl)-2-biphenylcarboxylic acid 4-(dodecylthio)butyric acid 4-(trifluoromethyl)mandelic acid n-alpha-boc-n-gamma-finoc-d-diaminobutyric acid 4-formamidobenzoic acid boc-11-aminoundecanoic acid 4-fluoro-2-methylphenoxyacetic acid : 7-amino-1,3-naphthalenedisulfonic acid 2,3-dibromo-3-(3,4-dimethoxyphenyl)propionic acid 3-[[(4-chlorophenyl)sulfonyl]methyl}-4-nitrobenzoic acid m-anisic acid 2' 4'-dimethyl-3.4,5,6-tetrachlorophthalanilic acid 3-bromothiophene-2-carboxylic acid
E 2-(thiobenzoyl)thiolacetic acid edta, aminobenzyl- : 2.3-dibromo-2'-methyl-4'-nitrosuccinanilic acid (1-carboxymethyl-3,3-dimethyl-cyclohexyl)-acetic acid 4'-ethyl-3,4,5,6-tetrachlorophthalanilic acid cis-1,2-cyclohexanedicarboxylic acid 4-ureidobenzoic acid 2-phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid 5-chloro-2-hydroxy-benzenesulfonic acid 3-ethoxy-4-hydroxyphenylacetic acid 3-(decyloxy)benzoic acid n-acetyl-dl-ethionine eicosa-5,8-dienoic acid 2,5-dihydroxybenzene-1,4-disulfonic acid 2-bromobenzoic acid 2-chloromandelic acid r-4-methoxymandelic acid 3-chloro-3'-methyl-biphenyl-2,2'-dicarboxylic acid p-nitrocinnamic acid 6-bromo-2-pyridin-4-yl-quinoline-4-carboxylic acid 4-fluoroglutamic acid benzo(c)phenanthrene-5,6-dicarboxylic acid
3-benzyloxythiophene-2-carboxylic acid 2-(4-methylbenzoyl)benzoic acid n-(phenylethyl)succinamic acid cyclohexane-1,1-bis-(3-mercaptopropionic acid) 2-iodo-5-methylbenzoic acid 1-(4-fluorophenyl)cyclohexanecarboxylic acid (adamantan-1-yloxy)-acetic acid fmoc-d-glutamic acid gamma-t-butyl ester 4-(tert-butoxycarbonylamino-methyl)-benzoic acid 9,10-dihydro-12-ethoxy-9,10-ethanoanthracene- 1 1-carboxylic acid 3-fluorophthalic acid cis-hexahydro-n-(2-methoxy-5-methylphenyl)phthalamic acid 2-bromo-5-iodobenzoic acid alpha-methyllevulinic acid
2.6-dibromo-benzoic acid n(2.4-dichlorophenyl)malonamic acid (+/-)-beta-p-chlorophenylglutamic acid
3-bromobenzoic acid
(+)-alpha-methyl-4-carboxyphenylglycine boc-l-glutamic acid gamma-t-butyl ester 4-(2-benzoylamino-3-methyl-but-2-enoylamino)-butyric acid 3-(n-(2,4,6-trimethylphenyl)carbamoyl)-5-norbornene-2-carbox ylic acid
1-(4-methoxyphenyl)- 1-cyclopentanecarboxylic acid n-alpha-(t-butyloxycarbonyl)-beta-(1-adamantyl ester)-l-aspartic acid 3,4-difluorophenylacetic acid chloric acid n-((r)-1-(1-naphthyl)ethyl)phthalamic acid hydroxy-2-naphthalenyl-methylphosphonic acid 3-(4-isopropyl-benzoyl)acrylic acid (3-methoxyphenyl)phosphonic acid
: 2,4-difluorobenzoic acid 2-(2,4,6-trimethylbenzoyl)benzoic acid (3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-acetic acid 2-ethyl-2-hydroxybutyric acid iminobis(methylphosphonic acid) 1-(aminocarbonyl)-1-cyclopropanecarboxylic acid (r)-(+)-3-hydroxy- 1-cyclopentene- 1 -heptanoic acid 2,3-dimethylsuccinic acid di-n-propylmalonic acid 4-dibenzo(a,d)cyclohepten-5-ylidene-butyric acid 15(s)-hydroxyeicosa-8z,11z,13e-trienoic acid 4-phosphono-benzoic acid cis-2'.5'-dimethylhexahydrophthalanilic acid cis-n-(2,3-dichlorophenyl)hexahydrophthalamic acid 3-(2-methoxy-benzoylamino)-benzoic acid (+/-)-1-aminocyclohexane-trans-1,2-dicarboxylic acid n-benzoyl-d-aspartic acid 2-(2-phenoxy-acetylamino)-3-phenyl-propionic acid trans-2-(p-methylbenzoyl)-1-cyclohexane-carboxylic acid n-alpha-(benzyloxycarbonyl)-gamma-(benzyl ester)-i-glutamic acid 4-bromobutyric acid beta-(3-acetoxyphenyl)propionic acid alpha-chloro-3,5-dimethyl-1-adamantaneacetic acid 1 1-dodecenoic acid (s)-cbz-oxaproline mesityiglyoxylic acid cyclopentylacetic acid 3-chlorosalicylic acid 2-methylglutaric acid n-alpha-(9-fluorenylmethyloxycarbonyl)-l-norvaline l-alpha-glutamyl-l-aspartic acid n-(4,6-dimethylpyrimidin-2-yl)-2-aminobenzoic acid 6-heptadecyloxy-1-hydroxy-naphthalene-2-carboxylic acid 1,3-phenylenedipropionic acid 4'-methyl-3'-nitromaleanilic acid tricosa-10,12-diynedioic acid dl-2-[4~(trifluoromethoxy)phenoxy Jpropionic acid n-(diphenylmethyl)glutaramic acid 2-benzoylpyridine-4-carboxylic acid 2,4,6-trichlorobenzoic acid 2-(2,4-dimethyl-benzyl)-benzoic acid 2,4-heneicosadiynoic acid 3-methyl-2-(ortho-tolyl)-butyric acid 2,3.4,5,6-pentachlorobenzoic acid 3,4-dichloropentafluorobutyric acid 3.4 4-trichloro-2-nitro-but-3-enoic acid 1,2.4-benzenetricarboxylic acid
S-mercapto-tetrazole- 1-propionic acid lauric acid 4-iodobutyric acid cis-8,11,14-eicosatrienoic acid 3-carboxy-4-hydroxy-5-sulfoaniline 2-furylthio pyruvic acid 2-chloro-5-nitrobenzenesulfinic acid n-alpha-(t-butyloxycarbonyl)-beta-(2-adamantyl ester)-l-aspartic acid
I-cis-pyrrolidine-2,4-dicarboxylic acid 2-amino-5-cyano-3-ethyl-benzoic acid 1-acetoxynaphthalene-6-sulfonic acid 5(s)-hydroxyeicosa-6e,8z,11z,14z-tetraenoic acid fmoc-d-norvaline 4-(n-(3-chlorophenyl)carbamoyl)butyric acid 3-methyl-1,1-cyclohexanediacetic acid
6-nitro-1-diazo-2-naphthol-4-sulfonic acid
2-(4-methoxyphenoxy)-5-nitrobenzoic acid
4 4'-diaminodiphenylamine-2,2-disulphonic acid : 2-methyloctadecanoic acid 2,6-difluorocinnamic acid 20-hydroxy-(5z,8z,11z,14z)-eicosatetraenoic acid 4-toluenesulfonylacetic acid
5-bromo-3-methylsalicylic acid
5-chlorovaleric acid
5-benzyl-3,6-dioxo-2-piperazineacetic acid 5-hydroxy-cyclohexane-1,3-dicarboxylic acid 3-bromo-2-methoxy-5-methyl-benzoic acid
2-furoic acid
5-(2,5-dichlorophenylazo)-4-methylsalicylic acid 4-((benzenesulfonylimino-phenyl-methyl)-amino)-benzoic acid 1-naphthylacetic actd
: 3-((furan-2-carbonyl)-amino)-benzoic acid trans-2,4-pentadienoic acid 3-(3-(2-chloro-6-methylphenyl)ureido)benzoic acid 2-(3-[2,2.2-trichloro-1-(2,2-di-me-propionylamino)-et)-thioureido)-benzoic acid 5.5'-dithiobis(2-nitrobenzoic acid) cis-hexahydro-n-(3-chloro-4-methylphenyl)phthalamic acid (z)-(2-(formamido)thiazol-4-yl)(methoxyimino)acetic acid pyridine-2-sulfonic acid
4-(tetradecyloxy)benzoic acid 4-cyclopentyl-naphthalene-1-carboxylic acid 4-(4-(1-methyl-1h-quinolin-2-ylidene)-but-2-enylideneamino)-benzoic acid 3-amino-2-naphthol-1,8-disulphonic acid
5-nitroorotic acid
4'-(2-furoylamino)-3'-hydroxymalonanilic acid (2-phenyl-cyclohexyl)-acetic acid
4-dodecyloxybenzoic acid
15-methylhexadecanoic acid (r)-(+)-2-chlorobutanoic acid 3-amino-1,5-naphthalene disulfonic acid isoindolin-1-one-2-acetic acid 2-(3-[n'-(3-methyl-butyryl)-hydrazino]-3-oxo-propionylamino)-benzoic acid (3,3-dimethyl-1-phenyl-1.3-dihydro-isobenzofuran- 1-yl)-acetic acid 2-methyl-4-naphthalen-1-yl-butyric acid
4-(chlorosulfonyl)benzoic acid
3-carboxy-2-furanacetic acid
3-[4-(4-bromophenylthio)-3-nitro phenyljacrylic acid bicyclo(2.2.1)heptane-1-carboxylic acid
2'-ethoxymaleanilic acid
3-nitro-5-(trifluoromethyl)benzoic acid p-(benzylsulfonamido)benzoic acid
3-(1-naphthyl)acrylic acid n-acetyl-8-hydroxy-2-naphthylamine-6-sulfonic acid [biphenyl-2-yl-(toluene-4-sulfonyl)-amino]-acetic acid n-acetylglycyl-d-glutamic acid
3-ethylheptanoic acid
7-chlorobenzofuran-2-carboxylic acid
3.5-difluorocinnamic acid 3-(3,4-dimethyli-phenyl)-3-methyl-butyric acid 5,8,11,14,17-eicosapentaenoic acid
2.4,6-trinitrobenzenesulfonic acid nervonic acid
5-methyl-2-phenylthiazole-4-yl acetic acid (5,6-dimethoxy-3-0x0-1,3-dihydro-isobenzofuran-1-yl)-acetic acid 1-methylcyclopropane-1-carboxylic acid dodecylbenzene sulfonic acid
3-ethylhexanoic acid
}-n-(1-carboxy-5-amino-pentyl)-iminodiacetic acid 4-hydroxy-3-nitrobenzoic acid di-n-butylphosphinic acid 4'-octyloxy-4-biphenylcarboxylic acid 2-diazo-1-naphthol-5-sulfonic acid : 4'-bromophthalanilic acid 2.6-dinitrotoluene-4-sulfonic acid n-acetyl-6-chloro anthranilic acid 4-(2-acetylamino-4,5-dimethyl-phenyl)-4-oxo-butyric acid 2,4-dinitrobenzenesulfonic acid ) 3-(2-chloro-3,4-dimethoxyphenyl) acrylic acid p-heptyloxybenzoic acid 4-chloro-3-hydroxybenzoic acid 3-(ac-(5-nitro-1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-amino)-benzoic acid 12-hydroxydodecanoic acid trichloroacrylic acid piperonylic acid 4-methoxy-alpha-methylcinnamic acid 5-benzyloxy-2-nitrophenylpyruvic acid 2-(2-hydroxy-1-naphthylmethyleneamino)benzoic acid 7-methoxy-2.2-diphenyl-benzo(1,3)dioxole-5-carboxylic acid 13-oxotetracosanoic acid dipropyl-phosphinic acid gibberic acid 3'-chloro-4'-methylsuccinanilic acid 1-hexadecenylsuccinic acid 3-bromo-4-hydroxy-5-methoxy-phenylacetic acid n-(2,4-dichlorobenzyl)-1,2,3,6-tetrahydrophthalamic acid 2,4-heptadecadiynoic acid (+)-4'-methyltartranilic acid 3,5-dimethyl-4-formyl-2-pyrrolecarboxylic acid
11(r)-hydroxy-(5z,8z,12¢,14z)-eicosatetraenoic acid n-formyl-4-(methylamino)benzoic acid succinic acid 2-(n-heptoxy)-butyric acid 2,3 4-trifluorocinnamic acid 3-(4-methoxy-2-methyl-phenyl)-propionic acid gamma-d-glutamyltaurine 4-chloro-3-fluorocinnamic acid 4-(5-indanylmethyleneamino)benzoic acid 2,4-difluoromandelic acid 5-oxoazelaic acid 3-[3-chloro-5-(trifluoromethyl)-2-pyridyl]propanoic acid trans-3-(4-methoxybenzoyl)acrylic acid n-alpha-(t-butyloxycarbonyl)-l-octahydroindole-2-carboxyii ¢ acid (s)-(+)-hexahydromandelic acid ~ n-(3-chlorophenyl)phthalamic acid n-(1-naphthyl)-maleamic acid 2-(4-tert-butylphenoxy)-2,2-difluoroacetic acid 2-ethylnonanoic acid 3-(5-bromo-2-ethoxyphenyl) acrylic acid fmoc-6-aminohexanoic acid chlorosuccinic acid gamma-d-glutamylaminoethylphosphonic acid 3-hydroxy-4,4,4-trichlorobutyric acid acetyl-d-aminoheptylic acid 3-(methoxycarbonylmethylthio)thiophene-2-carboxylic acid n~(1,1-bis(hydroxymethyl)ethyl)-3,4,5,6-tetrachlorophthalamic acid 1,1-cyclopropanedicarboxylic acid 4 amino acetanilide 2 sulphonic acid 2-(4-hexyl-benzoylamino)-benzoic acid 4 4'-(carbonyldiimino)bis-benzoic acid
3-isobutyrylamino-3-(4-methoxy-phenyl)-propionic acid biphenyl-3,5-dicarboxylic acid 3,3-dimethyl-4-oxovaleric acid pinonic acid 3-chloro-pentanedioic acid giberellic acid 3-(nonylamido)benzoic acid 4-(trifluoromethyl)benzoic acid ) 3-(allylsulfanyl)-2-thiophenecarboxylic acid 3',4'-dibromophthalanilic acid 3-hydroxynonaoic acid 3-(4-0x0-3,4,5,6,7.8-6h-benzo[4,5]thieno[2.3-d]pyrimidin-2-yl)-propionic acid 4-(4-phenoxy-benzoyl)-benzoic acid 2,5-diiodobenzoic acid 3-(n-(2.4-difluorophenyl)carbamoyl)-5-norbornene-2-carboxylic acid benzo(c)phenanthrene-3-carboxylic acid 2-methyl-2-(7-methylindan-4-yloxy)propionic acid : exo-2-bromo-5,5-ethylenedioxy-bicyclo[2.2.1 Jheptane-syn-7-carboxylic acid 3-methoxy-2,4,5-trifluorobenzoic acid (+)-2-(1-naphthoxy)propionic acid 2,2-dichloro-1-methyl-cyclopropanecarboxylic acid 2-fluoro-4-(trifluoromethyl)phenylacetic acid (+/-)-azetidine-2-one-4-carboxylic acid 4-(3-(3,5-di-tert-butyl-4-hydroxy-phenyl)-3-oxo-propenyl)-benzoic acid levulinic acid dimethyl phosphate 2,4-dinitrophenylacetic acid 3,4-dichlorobenzenesulfonic acid boc-3-aminobenzoic acid 3,4-dimethylbenzoic acid 2-fluoro-5-methylbenzoic acid
: n-alpha-(9-fluorenylmethyloxycarbonyl)-1-2-amino-5-ureido-n -valeric acid o-nitrobenzoic acid 2,3-dibromosuccinic acid beta-s-(4-methoxybenzylmercapto)-isovaleric acid 4-bromo-7-0x0-6-0xa-bicyclo(3.2.1)octane-2-carboxylic acid 1-pentanesulfonic acid
5-hydroxyisophthalic acid s-4-chloromandelic acid 1-hydroxy-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid 3-acetamido-3-methylbutyric acid
3'-(trifluoromethyl)succinanilic acid 2-meo-4-methyl-6-(2,2,2-trichloro-1-hydroxy-ethyl)-cyclohexanecarboxylic acid 4-ethoxycinnamic acid
5-bromo-isophthalic acid
2'-chloro-5'-nitrophthalanilic acid
2-methyl-3-p-tolyl-acrylic acid 5.5.6,6.7,7,7-heptafluoro-4,4-bis(trifluoromethyl)-2-heptenoic acid 2' 4'-dimethylmaleanilic acid
4-acetoxybenzoic acid
3.6-disulfo-naphthalene-1,8-dicarboxylic acid
(r)-(-)-citramalic acid
1-octanesulfonic acid
2-methyl-2-phenyl-hexanedioic acid
3-noradamantanecarboxylic acid 2-cyano-3-(3,4-dihydroxy-5-methoxy-phenyl)-acrylic acid 3.5-dinitro-4-hydroxyphenylacetic acid 2-chloro-3,4-dimethoxybenzoic acid 5-(trifluoromethyl)thieno[3,2-b]pyridine-6-carboxylic acid 9.,9-dihydroxy-5-oxo-nonanoic acid diisooctylphosphinic acid boc-nipecotic acid
3 4-dichloro-2-thiophenecarboxylic acid n-alpha-fmoc-n-gamma-aloc-l-diaminobutyric acid oo cis-2-(tert-butoxycarbonylamino)-1 -cyclopentanecarboxylic acid boc-4-aminobenzoic acid phosphatidic acid cis-3',4'-dimethylhexahydrophthalanilic acid 1,2,3-triazole-4,5-dicarboxylic acid : n-(3-nitrophenyl)-1,2,5,6-tetrahydrophthalamic acid 3-((2-carboxy-ethyl)-(4-methyl-thiazol-2-yl)-amino)-propionic acid 2,3 ,4-trimethyl-cyclobutanecarboxylic acid 5-(2'-(3"-chloro-5'"-trifluoromethyl)pyridylamino)methyl-3 4-dihydro isoxazole-2- 3-(n-cthylthiocarbamoylthio)-propionic acid n-alpha-boc-n-beta-bromoacetyl-I-diamino-propionic acid : trans- 1,2-cyclohexanediacetic acid : 2,6-diflucromandelic acid cis-n-(2-chloropheny)hexahydrophthalamic acid 2,6-dichloropyridine-4-carboxylic acid n-(1-naphthyl)-1,2,3 ,6-tetrahydrophthalamic acid 3-(trifluoromethylthio)benzoic acid n-(2-bromophenyl)maleamic acid beta-glutamic acid 6-hydroxy-1-naphthoic acid 4-(2-thienylmethyleneamino)benzoic acid n-(2,4-dimethoxy-phenyl)-phthalamic acid heptafluoro-2-hexenoic acid (4-benzyloxy-3-methoxy-2-nitro-phenyl)-acetic acid : 3-(4-chlorophenyl)propionic acid boc-1-beta-aminobutyric acid (4-fluorophenylthio)acetic acid (2-isopropylsulfanyl-acetylamino)-acetic acid 2-(3 5-dinitro-thiophen-2-ylamino)-pentanedioic acid
3,3'-dichloropivalic acid (2-butyryl-phenoxy)-acetic acid styrene phosphonic acid {-(2-fluorophenyl)cyclopentanecarboxylic acid 2-(2,3-dimethoxystyryl)glyoxylic acid 3,5-di-tert-butylsalicylic acid 2-(pentamethylbenzoyl)benzoic acid 4-ethyl-2-pyridinecarboxylic acid n,n'-dodecamethylenebis(glutaramic acid) n-cbz-(2r,3r)-3-amino-2-hydroxy-4-phenyl-butyric acid carboxymethanesulfonylmethanesulfonyl-acetic acid 3-(2,3 ,4-trimethoxyphenyl)propionic acid 17-(p-toluenesuifonyloxy)-heptadecanoic acid 4-((2-hydroxy-5-nitro-benzylidene)-amino)-benzoic acid 4-((naphthalen-1 -ylmethylene)-amino)-benzoic acid 3-benzoyl-3-benzylidenepropionic acid valeryl salicylate 3 4-diphenyl-cyclobutane-1 ,2-dicarboxylic acid 2-chloro-5-(trifluoromethyl)benzoic acid 3-pyridinepropionic acid 4-(2,5-bis-(2,2-dimethyl-propyl)-phenoxy)-butyric acid 3-(octadecyloxy)benzoic acid (r)-(+)-2-bromopropionic acid 3 4-dihydro-6-methoxy-1-naphthoic acid 2-nitro-4-(2,2,2-trifluoro-1-hydroxy-1 -trifluoromethyl-ethyl)-benzoic acid glycolic acid 2-isoquinolin- 1-ylmethyl-benzoic acid 3,4 4-trichloro-2-dichloromethylene-but-3-enoic acid 4-methyl-2-phenyl-1 2,3-triazole-5-carboxylic acid 3-bromo-4-fluorocinnamic acid 8-nitro-quinoline-4-carboxylic acid
3.(3-me-5-oxo0-4,5-dihydro-pyrazol-1 _yl)-2-phenylcarbamoyl-benzenesulfonic acid 4-(trifluoromethylthio)benzoic acid 4-(3-(2-ethylphenylureido)salicylic acid 7'-ethylmaleanilic acid p-xylene-2-sulfonic acid 2.3.4,4,5,5,5-heptafluoro-2-pentenoic acid 4-jodo-3-nitrobenzoic acid 2-benzoylamino-3-(diethoxy-phosphoryl)-3-phenyl-acrylic acid 4 4'-dinitrostilbene-2,2'-disulfonic acid trans-4-n-butylcyclohexanecarboxylic acid 3 4-difluoro-5-(trifluoromethyl)phenylacetic acid 2 -nitro-alpha,alpha,alpha-trifluoro-p-toluic acid 2 4-dichloropyridine-5-carboxylic acid . 2-(morpholine-4-carbothioylsulfanyl)-propionic acid alpha-methyl-4-nitrocinnamic acid 6-methyl-2-phenylimidazo[l 2-apyridine-3-carboxylic acid (1-2-3 4-dimethoxy-phenyl)-ethyl)-5-ethyl-2-oxo-piperidin-4-yl)-acetic acid 5-carboxyvanillic acid 3 _benzyl-quinoline-4-carboxylic acid 3-(4-methylthiobenzoyl)propionic acid n-(2-benzylsulfanyl-benzothiazol-6-yl)-succinamic acid 3.(8-benzyl-9-0x0-6,7,8.9-tetrahydro-Sh-benzocyclohepten-8-ylpropionic acid succinanilic acid n-tosyl-3-pyrrolecarboxylic acid 2-ethyl-3-(4-methoxy-phenyl)-acrylic acid butyric acid (1alpha,2alpha,3beta.4beta)-2.4-bis(4-hydroxyphenyl)- 1 3-cyclobutanedicarboxylic acid 3 4-difluoro-5-(trifluoromethyl)benzoic acid 2.3,5,6-tetrafluoro-p-toluic acid 2-bromo-4,5-dimethoxybenzoic acid 3.(2-benzoylamino-3-(4-methoxy-phenyl)-acryloylamino)-propionic acid
5-nitro-1,2,3,4-tetrahydro-1 4-ethenonaphthalene-2,3-dicarboxylic acid 3-(4-n-heptylbenzoyl)propionic acid (1-oxo-decahydro-naphthalen-2-yl)-acetic acid -(carborxy-hydroxy-methyl)-6-hydroxy-4-methyl-cyclohexanecarboxylie acid n-furfurylphthalamic acid
3(2-furyl)-2-oximino propionic acid 10,1 1-dihydroxy-undecanoic acid 2-thioorotic acid 2'_chloro-5'-nitroglutaranilic acid g8-nonynoic acid
(rs)-1 -aminoindan-1,5-dicarboxylic acid
4-(3,5-diisopropyl-benzoylamino)-benzoic acid
2-butyl-3-(2-methoxy-phenyl)-acrylic acid n-finoc-1-amino-cyclopropane- 1 -carboxylic acid iminodiacetic acid bis(p-nitrophenyl) phosphate
>-benzoylamino-3-(3,4-dimethoxy-phenyl)-propionic acid
3-(3,5-dimethyl-naphthalen-2-yl)-2-methyl-butyric acid 2-ethoxy-4-methoxybenzoic acid d1-2-hydroxy-n-butyric acid (2-carbamoylphenoxy acetic acid 5-acetylsalicylic acid n-benzylphthalamic acid n-(4-methylphenyl)maleamic acid {-leucyl-1-glutamic acid : (4-(3-methyl-ureido)-benzoylamino)-acetic acid arabinic acid
9-methylundecanoic acid
2-(methylthio)benzoic acid arachidonic acid
2 4-dichlorophenylacetic acid
2-dibenzothiophenepropionic acid 3-(3 4-ethylenedioxybenzoyl)propionic acid 2-methyl-2-(4-methyl-3-oxocyclohexyDmalonic acid 8-cyano-naphthalene-1-sulfonic acid 5-(methylthio)thiophene-2-carboxylic acid 2-bromodecanoic acid 2-isopropylideneaminooxy-butyric acid allylmalonic acid ) 3 5-dimethoxy-4-methylbenzoic acid alpha-(4-methoxy-1 -naphthyl)-o-toluic acid 3-(4-ethoxyphenyl)propionic acid 0 3.(2-nitro-4-trifluoromethylphenoxy)-2-thiophenecarboxylic acid 3-(2,6-dichloro-phenyl)-2-methyl-acrylic acid 4-(4-cyano-phenoxy)-benzoic acid ’ chlorendic acid 12-formyl-tricyclo(8.2.2.2(4,7))hexadeca-hexaene-S-carboxylic acid ) n-(2,6-dimethylphenyl)- 1,2,3,6-tetrahydrophthalamic acid poly-1-glutamic acid (s)-(+)-ketopinic acid 34 5-trimethoxy-2-nitro-benzoic acid homovanillic acid 8-chloro-4-dibenzofurancarboxylic acid 5,6a,7,7 a-tetrahydro-4h-cyclopropa(e)acenaphthylene-7-carboxylic acid 3-(n-(2,6-xylyl)carbamoyl)propionic acid (4-methoxyphenyl)phenylphosphinic acid 4-acetamidobutyric acid trans-norpinic acid fmoc-(3r,4s)-4-amino-3-hydroxy-6-methylheptanoic acid 3.4,5,6-tetrachloro-pyridine-2-carboxylic acid 2'-methoxy-5'-methylmaleanilic acid 3-(octane-1 -sulfonyl)-propionic acid
2-chloropropionic acid 4-(4-(1,3-dioxo-1 3-dihydro-isobenzofuran-5-carbonyl)-phenoxy)-benzoic acid 12-methyltetradecanoic acid triphenylacetic acid 3-methyl-1 -oxo-isochroman-5-carboxylic acid (4-phenyl-5-phenylamino-4h-(1,2,4)triazol-3-ylsulfanyl)-acetic acid 9-hydroxyimino-9,1 0-dihydro-anthracene-1-carboxylic acid 7-methoxy-1-methyl-4-0x0-2,3 4.5-tetrahydro-1h-benzo[d] azepine-2-carboxylic acid 2,5-dichlorophenylthioglycolic acid 1-cyanocyclopropanecarboxylic acid 2 6-dinitromesitylene-4-sulfonic acid 3-(4-hydroxy-3-methoxy-phenyl)-2-methyl-acrylic acid 3-(4-cyclohexylbenzoyljacrylic acid 2-cyano-2-methyl-3-phenyl-propionic acid 2.3-dimethoxyphenylacetic acid n-alpha-(benzyloxycarbony!)-gamma-(benzy! ester)-d-glutamic acid n-(4-methoxyphenyl)tetrachlorophthalamic acid 4-phenylbutyric acid 3-nitrobenzaldehyde-4-sulfonic acid n-octadecylsuccinic acid pyridine-4-sulfonic acid 2-hydroxy-2-trifluoromethylbutyric acid 2,6-dimethyl-terephthalic acid terephthalic acid 3,5-di-tert-butyl-4-hydroxycinnamic acid : 3-ethoxypropionic acid 4-allyl-2-methoxyphenoxyacetic acid d-(-)-diisopropyl-d-tartaric acid 4-bromomethyl-naphthalene-1 -carboxylic acid 7'_chloro-6'-methylsuccinanilic acid 2' 4'-dimethoxyhexahydrophthalanilic acid
2, 7-difluoro-9-oxo-4-fluorenecarboxylic acid 2-methoxy-6-(2,2-dimethylpropionamido)cyclohexanecarboxylic acid 3-hydroxyphenylacetic acid 6-iodohexanoic acid 3-bromo-2,6-dimethoxybenzoic acid 3-(4-chlorophenyl)-2-phenyl-propionic acid (s)-(-)-2-chloro 3-methylpentanoic acid alpha-chloro-3-(trifluoromethyl)-hydrocinnamic acid 3-(hexadecane-1-sulfonyl)-propionic acid 12(s)-hydroxy-(5z,8¢,1 0e)-heptadecatrienoic acid 1,3,5-cyclohexanetricarboxylic acid 3-hydroxy-4,5-dimethoxy-benzoic acid 4-bromo-1,2,3,4-tetrachloro-1 ,3-butadiene-1-carboxylic acid (2.,4-xylyl)phosphonic acid : 4-bromo-3-methoxy-naphthalene-2-carboxylic acid
LC (4/-)-threo-4-methylglutamic acid levulinic acid oxime cis-13-octadecenoic acid 4-(methylsulfonyl)benzoic acid (3-methoxy-4-phenoxy-phenyl)-acetic acid carboxypyrazolone-2,5-disulfonic acid 5-methoxy- 1-indanone-3-acetic acid tnp-1-glutamic acid 4-chlorobutyric acid 1 naphthyl amine 2,4,7, trisulfonic acid 6-hydroxy-3 -oxo-7a-propionyl-octahydro-indene-1 -carboxylic acid furan-2,5-dicarboxylic acid alpha-(4-chlorophenyl)-4-nitrocinnamic acid 2-bromovaleric acid 2.2-diethylbutyric acid dl-glutamic acid
4-(4-hydroxybenzylideneamino)salicylic acid (s)-(+)-2-methylbutyric acid n-alpha-n-beta-bis-boc-I-diaminopropionic acid 2,2-diphenylpropionic acid 1-hydroxy cyclohexane carboxylic acid stearic acid 2-(2-carboxy-ethylamino)-succinic acid coumarin-3-carboxylic acid 4-(2-(4-tert-octylphenoxy)ethoxy)benzoic acid 2-(2-chioro-4-fluorophenylthio)acetic acid 5-bromo-2-methyl-benzoic acid myristic acid cis-10-nonadecenoic acid 2-bromo-4-fluorocinnamic acid {-(4-methylbenzenesulphonyl)indole-3-acrylic acid 1-et-6-fluoro-7-hydroxy-4-oxo-1,4-dihydro-(1 ,8)naphthyridine-3-carboxylic acid 3 4-diethoxyphenylacetic acid 12(r)-hydroxy-16-heptadecynoic acid 4-chlorobenzenesulphinic acid 11-bromo-undec-10-ynoic acid 3-[(4,6-dimethoxypyrimidin-2-yloxypyridine-2-carboxylic acid 3.4,5-trimethoxybenzoic acid 2-fluoro-4-octyloxybenzoic acid 4-methyl-2-thioxo-2,3-dihydro-thiazole-5-carboxylic acid 4-methyl-2-pentenoic acid : 2-carboxymethyl-2-methyl-cyclohexanecarboxylic acid 7-hydroxy-4-methyl-cumarone-3-yl acetic acid 1,5-pentanebisphosphonic acid trans-3-furanacrylic acid 3-acetamido-p-toluic acid 3-[4-(methylsulphonyl)phenyl]-(2¢)-propenoic acid
4-fluoro-2,3,5,6-tetramethyl-benzoic acid 4-tricyclo(4.3.1.1(3,8)undecanecarboxylic acid 2-methoxy-4-nitrobenzoic acid vanillic acid n-(4-acetylpheny!) maleanilic acid taurine-n,n-diacetic acid 4.5,5,5-tetrafluoro-4-(heptafluoropropoxy)pentanoic acid diethylmalonic acid 3-(3-(3-(trifluoromethyl)phenyl)ureido)benzoic acid 5-bromo-2-nitrobenzoic acid 2-(4-cinnamoylphenoxy)acetic acid adrenic acid tetracosanoic acid 3-(trifluoromethyl)anthranilic acid 3-(2-0-tolyloxy-acetylamino)-benzoic acid n-(2,4,6-trimethylpheny!)glutaramic acid 2' 4'-dichlorosuccinanilic acid 2,3-dihydrobenzo{b]furan-5-carboxylic acid 3-(2-chlorophenyl)propionic acid 2-fluoropalmitic acid 5-(4-methoxyphenyl)-2,3-dihydro-1 h-pyrrolizine-6,7-dicarboxylic acid (5-cyano-2-(4-methoxy-phenyl)-6-oxo-cyclohex- 1-enyl)-acetic acid glutathionesulfonic acid 4-(4-acetamidophenylimino)-2,3-dichloro-2-butenoic acid (4-benzyloxy-3-methoxy-phenyl)-acetic acid : 2-phenyl-hexanedioic acid 4-methyl-2-oxovaleric acid 2'-benzoyl-4'-chloromaleanilic acid 5,6-acenaphthenedicarboxylic acid 5-(2-chloro-5-(trifluoromethyl)phenyl)-2-furoic acid 3-(2,4-dimethylbenzoyl)propionic acid
2-fluoro-3-(trifluoromethyl)phenylacetic acid 4,5-dihydro-1 -(methylthio)benzo[c]thiophene-3-carboxylic acid (2-carboxymethyl-cyclopropyl)-acetic acid 2-(butylcarbamoyl)benzoic acid 3-allyloxypropionic acid 2'-carbamoyl-biphenyl-2-carboxylic acid 6-(1,3-dioxo-1h,3h-benzo(de)isoquinolin-2-yl)-hexanoic acid 3 5-diisopropylsalicylic acid 4-ethylbenzenesulfonic acid boc-1-pipecolic acid 2.6-dichloro-4-(trifluoromethyl)phenylacetic acid 3-thiophenemalonic acid 3-hydroxy-2.2-dimethyl-3-phenylpropionic-acid 3-(9-methyl-9h-fluoren-9-yl)-butyric acid 2-(1 2.3,4.5-pentahydroxy-pentyl)-thiazolidine-4-carboxylic acid di-atrolactic acid n-t-boc-(2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid 2-(1-naphthoyl)benzoic acid 1-(2-(3-chloro-5-trifluoromethylpyridyl)indole-3-propenoic acid 4'-butylmaleanilic acid 4-fluoro-3.5-dimethyl-benzoic acid 4-chloro-3-fluorobenzoic acid n-alpha-fmoc-n-gamma-boc-d-diaminobutyric acid cyclohexa-2,4-dienyl-(2,3,5,6-tetramethyl-phenyl)-acetic acid 8-(4-methoxy-phenyl)-6-methyl-8h-[1 3)dioxolo[4,5-g]chromene-7-carboxylic acid 1 }-(4-chloro-phenylsulfanyl)-undecanoic acid 1.3-dioxo-2-p-tolyl-2,3-dihydro- h-isoindole-5-carboxylic acid cis-2-(p-methylbenzoyl)-1 -cyclohexane-carboxylic acid mucic acid 4'-(methylthio)succinanilic acid 3-ethoxy-2-butenoic acid acetoxyacetic acid 5-methyl-2-nitrobenzoic acid : 4-chloro-2-fluorobenzoic acid 2,5-dimethoxycinnamic acid (+/-)-beta-phenylglutamic acid 3-methyl-2-oxobutyric acid 1-heptane sulfonic acid 4-methyl-3-nitrobenzoic acid 2-carboxycinnamic acid alpha-methylcinnamic acid 4-(3-hexadecyl-2-thioureido)-benzoic acid dehydroabietic acid (2-nitro-benzenesulfonylamino)-acetic acid (3-benzyloxy-4-methoxy-phenyl)-acetic acid 5-bromo-2-iodobenzoic acid 1,1,3-trimethyl-3-phenylindan-4',5-dicarboxylic acid : oxalacetic acid 2-aminoterephthalic acid perfluorohexanoic acid 2,6-dichlorophenylacetic acid 6-bromo-2-pyridin-3-yl-quinoline-4-carboxylic acid 4-(chloromethyl)benzoic acid 2-(4-isopropylbenzoyl)acrylic acid 5-iodoferulic acid 3-(1,2,3,4-tetrahydro-naphthalen-1-yl)-propionic acid 2-[3-o0x0-3-(n'-tridecanoyl-hydrazino)-propionylamino]-benzoic acid 2'-carbamoyl-3,4,5,6-tetrachlorophthalanilic acid 4-(2,6-dibromo-1h-indol-3-yl)-butyric acid (4-bromo-benzoylamino)-acetic acid diethylphosphonobutanoic acid 4-amino benzyl sulfonic acid n-benzoyl-8-hydroxy-2-naphthylamine-6-sulfonic acid 2,6-dimethylphenoxyacetic acid p-hydroxyhippuric acid n-(3-(trifluoromethyl)benzoyl)glycine (2-phenoxy-acetylamino)-acetic acid 8-methylnonanoic acid 3-(3-methoxy-phenyl)-2-methyl-acrylic acid 2-(2,4-dibromophenoxy)-propionic acid 4-pitrosalicylic acid 4-(3-(4-acetyl-phenyl)-propyl)-benzoic acid (s)-(-)-2-acetoxypropionic acid 5-(phenylazo)salicylic acid 5-carboxydehydroacetic acid dimethyldianilinoterephthalic acid phenyl cyclohexyl oxyacetic acid 3,4-dichlorophenoxyacetic acid n-(2,6-diisopropylphenyl-carbamoylmethyl)iminodiacetic acid 3-(4-n-propylbenzoyl)propionic acid trans-3-hexenoic acid -beta-amino adipic acid 3-(4-chlorobenzylthio)thiophene-2-carboxylic acid 3-(1,1,2,2-tetrafluoroethoxy)benzoic acid
S-acetyl-4-hydroxy-3-methoxy-furan-2-carboxylic acid 2,4-dihydroxy-5-(isobutylthio)-benzenesulfonic acid 3-acetoxycinnamic acid 1-amino-2-(3-indolyl)ethane phosphonic acid 2-fluoro-4-propoxybenzoic acid 3-(4-chlorobenzoyl)-2-(4-isopropylphenyl)propionic acid 2-acetyl-3,6-dimethylbenzoic acid 2'.5'-dichlorosuccinanilic acid 2-hydroxy-3(s)-(n-tert-boc-amino)-heptanoic acid
(-)-n-(phenylsulfonyl)glutamic acid (z-styrylthio)acetic acid gamma-d-glutamylaminomethylsulfonic acid dodecyloxy-acetic acid 4'-(methylthio)-3,4,5,6-tetrachlorophthalanilic acid alpha-methyl-2-(methylthio)-5-nitrocinnamic acid 1-(p-tolyl)-1 -cyclopropanecarboxylic acid 3-(hexadecylsulfonamido)-propionic acid (2s)-alpha-ethylglutamic acid ethylene glycol bis(4-carboxyphenyl) ether (+)-n-benzoylglutamic acid alpha-ketovaleric acid 2.3-diacetoxy-n-(1-naphthalen-1-yl-ethyl)-succinamic acid = 5-methyl-1h-(1,2,3)triazole-4-carboxylic acid dipivaloyl-d-tartaric acid it 3-(4-benzyloxy-3-methoxy-phenyl)-propynoic acid : 1-(4-bromobenzoyl)piperazine-2,3-dicarboxylic acid dl-cyclopentylmandelic acid 1-(4'-sulfophenyl)-3-methyl-5-pyrazolone 2',5'-dichloroglutaranilic acid perfluoropentanoic acid 4-hydroxymethyl-3-pyridinecarboxylic acid n-boc-aminoheptanoic acid 2,3,5-trichlorobenzoic acid 2,2-dimethylsuccinic acid benzoic acid d-isoascorbic acid dl-phenylmercapturic acid . n-fmoc-l-aspartic acid-beta-benzyl-ester 2-chloro-4,5-difluorobenzoic acid glyoxylic acid
9-methyl-9h-fluorene-2-carboxylic acid
(2,3,4,5,6-pentahydroxy-hexanoylamino)-acetic acid 4-(hexadecylthio)benzoic acid 3-(5-hydroxy-4-methoxy-2-nitro-phenyl)-acrylic acid trifluorothiolacetic acid n-formyl-dl-2-amino-n-butyric acid
4-ketopimelic acid
3,4,5-trimethoxycinnamic acid 2,5-dibromo-3,6-dichloro-terephthalic acid 1-fluorenecarboxylic acid 2-(2-chloro-1,1,2-trifluoroethylthio)-benzoic acid
1 1-(5-azido-1-naphthoxy)undecanoic acid 2-(2,5-dimethoxy-benzyl)-benzoic acid 3,8-dioxa-tricyclo(5.1.0.0(2,4))octane-5,6-dicarboxylic acid 2-cyclopentylhexanoic acid 2-(4-(2,2-dicarboxy-ethyl)-2,5-dimethoxy-benzyl)-malonic acid 2-methyl-non-2-enoic acid (4,4-dimethyl-3-oxo-cyclohexyl)-acetic acid 2-carboxymethyl-5-methoxy-benzoic acid trans-4-hydroxy-4-(4-nitrophenyl)-2-butenoic acid 3-(2,6-diethyl-phenylcarbamoyi)-acrylic acid 2-[2-(3-methoxy-phenyl)-acetylamino}-3-methyl-butyric acid
11,12-epoxy-(5z,8z,14z)-eicosatrienoic acid 2-bromobutyric acid phthaly!-di-glutamic acid 4-nitro-2-(3-nitrophenoxy)benzoic acid 4-methoxycyclohexanecarboxylic acid
3-methyl-3-(3,4,5-trimethyl-phenyl)-butyric acid
2-(difluoromethoxy)benzoic acid n-(3,4-dichlorophenyl)malonamic acid thiodisuccinic acid
5-chlorobenzo[b]thiophene-3-acetic acid 4-benzyloxy-3-methoxycinnamic acid 2-propylnonanoic acid indazole-3-carboxylic acid anthraquinone-2-carboxylic acid boc-6-aminocaproic acid fmoc-nipecotic acid
. 4-((2-hydroxy-5-methoxy-benzylidene)-amino)-benzoic acid hydroferulic acid pth-di-cysteic acid (+/-)-cis-1-amino-1-carboxycyclopentane-3-acetic acid 1 naphthol 3,6,8 trisulfonic acid 3-(4-chlorobenzoyl)-2-(4-fluorophenyl)propionic acid
: n-carbamyl-dl-alanine cis-hexahydro-n-(2-phenethyl)phthalamic acid immobilized iminodiacetic acid trans-2-(4-fluorobenzoyl)- 1-cyclohexane-carboxylic acid 2-pyridylacrylic acid 4-tert-butyl-3-nitrobenzoic acid 3-(4-methyl-3-nitrophenylureido)benzoic acid 2-benzhydrylidene-succinic acid 3-pentanoic acid 2-(1-indenylidene)glycolic acid 1h,1h,2h,2h-perfluorodecanoic acid 4-(3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-butyric acid 3-(3-bromo-4-hydroxy-phenyl)-propionic acid 2-chloro-6-methylphenoxyacetic acid alpha,beta-dibromo-4-nitrohydrocinnamic acid alpha-(phenylthio)-o-toluic acid heptacosanoic acid
3,5-dibromo-2,4-dihydroxybenzoic acid 5-(9,10-diox0-9,10-dihydro-anthracen-2-yl)-penta-2,4-dienoic acid 9-fluorenone-4-carboxylic acid alpha,alpha,alpha',alpha’-tetramethylheptanedioic acid (+/-)-trans-2,3-piperidinedicarboxylic acid 4 5-dichloro-isothiazole-3-carboxylic acid 2-iodophenylacetic acid 4-jodophenoxyacetic acid 1-amino-8-naphthol-3,6-disulfonic acid 4-((4-chloro-benzylidene)-amino)-benzoic acid 2-cyano-3-methyl-but-2-enoic acid 3-((adamantane- 1-carbonyl)-amino)-benzoic acid 5-(trifluoromethoxy)indole-2-carboxylic acid meso-2,3-diphenylsuccinic acid cyclopentanecarboxylic acid 2-formylamino-2-pheny!-propionic acid gallic acid n-(2-butylsulfanyl-benzothiazol-6-yl)-succinamic acid 3-nitro-alpha-phenyicinnamic acid 4-methoxyphenoxyacetic acid hex-4-ynoic acid 5-(4-methoxybenzoyi)thiophene-2-acetic acid 2-methyl-5-phenylfuran-3-carboxylic acid 3-((5-nitro-1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-amino)-benzoic acid n-ethyl-d-aspartic acid dl-beta-hydroxycapric acid 3,5-dimethyl-2-iodobenzoic acid 2-ethyl-2-methylhexanoic acid diglycolic acid glutaconic acid 3-chloro-4-fluorobenzoic acid tricyclo(8.2.2.2(4,7))hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxylic acid 5-iodovanillic acid 3-methylcinnamic acid 2-bromooctanoic acid 2-bromo-6-methoxybenzoic acid x boc-8-aminocaprylic acid © 1,8-naphthyridine-2-carboxylic acid 3-(4-sulfamoyl-phenyl)-acrylic acid 2-(3-(2,4-xylyl)ureido)benzoic acid : 3-(3-thienyl)acrylic acid 2,2-dimethyl-3-hydroxypropionic acid n.n-bis((r)-(+)-1-phenylethyl)phthalamic acid i 1.3-phenylenediacrylic acid 2-(2-(2-hydroxy-1-naphthoyl)vinyl)benzoic acid (+/-)-erythro-4-methylglutamic acid £3 7-(3-chloro-2-thienyl)-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-carboxylic acid 4-chloro-3-iodobenzoic acid 2-[2-chloro[(4-fluorophenyl)sulfonyl}anilino]acetic acid glycyl-l-aspartic acid 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid 2-nitrobenzenesulfonic acid 3-(1.1.4.6.7-pentamethyl-indan-5-yl)-acrylic acid 2.5-dimethylphenoxyacetic acid hypophosphorous acid pyromellitic acid 2-methyl-2-phenyl-butyric acid 3-hydroxy-2,4,6-tribromobenzoic acid 1-(2-fluorophenyl)cyclohexanecarboxylic acid 3,4-dimethylhippuric acid 6,8-dichloro-2-hydroxy-4-quinolinecarboxylic acid n.n'’-(1,3-phenylene)dimaleamic acid :
1-butanesulfonic acid 2,3-difluorocinnamic acid triphenylsilylcarboxylic acid ethylphosphonic acid chlorogenic acid (1r,2s,3r)-1-hydroxy-3-hydroxymethyl-1,2,3 4-tetrahydronaphthalene-2-carboxylic acid adamantan-2-yl-acetic acid alpha-methy]-2-furanacrylic acid 4-oxatetradecanoic acid 2'.5'-dimethyl-3,4,5,6-tetrachlorophthalanilic acid 4 4-diphenyl-but-3-enoic acid 4 anisidine 2,5 disulfonic acid 2-((3-allyl-2-hydroxy-benzylidene)-amino)-3-(1h-imidazol-4-yl)-propionic acid benzylphosphonic acid methanesulfonylacetic acid 4 4-bis-(4-hydroxy-3-nitrophenyl)-valeric acid acrylic acid 1-(4-chlorophenyl)ethyliminoxy acetic acid 2-(2-chloro-1,1,2-trifluoroethoxy)-benzoic acid cis-2-(p-chlorobenzoy!)- 1-cyclohexane-carboxylic acid 3-acetamidobenzoic acid 2,4-bis(trifluoromethyl)benzoic acid 4-fluorocinnamic acid n-acetyl-d,l-homotryptophan benzofurazan-5-carboxylic acid cis-n-(5-chloro-2-methoxyphenyl)hexahydrophthalamic acid 3-(3,4-dichloro-pheny!)-2-methyl-acrylic acid 4-chloro-2-iodobenzoic acid n-phenylanthranilic acid (+/-)-trans-2,5-piperidinedicarboxylic acid 4-cyano-3,5-dimethyl-1h-pyrrole-2-carboxylic acid
3'-(trifluoromethyl)-1,2,3 6-tetrahydrophthalanilic acid 3-anthracen-2-yl-propionic acid n,n'-(1,2-phenylene)dimaleamic acid (t)-(-)-4-methylglutaric acid 1-monomethy! ester - 3-oxo0-2-phenyl-1-cyclopentanecarboxylic acid
I-homocysteinesulfinic acid 2-(ortho-tolyl)-heptanoic acid 1-(-)-threo-3-hydroxyaspartic acid : 4-chloro-3-sulfamoyl-benzoic acid 3-(4-chloro-phenyl)-3-isobutyrylamino-propionic acid decanoic acid 2-chloroethylphosphonic acid beta-d-aspartylaminomethyl-phosphonic acid -. 3-n-propylglutaric acid alpha-acetamidocinnamic acid epsilon-n-oxalyl-d-alpha, epsilon-diaminohexanoic acid iE d-camphoric acid 3-(1h-1ndol-3-y1)-2-(toluene-4-sulfonylamino)-propionic acid alpha-methoxycinnamic acid costic acid 4-ox0-4-(2-oxocyclohexyl)butyric acid n-(2-methoxyphenyl)maleamic acid 4-ethoxycarboxy-3,5-dimethoxybenzoic acid 2-fluoren-9-ylidenemethyl-benzoic acid 4-dipropylamino-3,5-dinitro-benzoic acid 7,10,13,16,19-docosapentaenoic acid 4-(3-chloro-5-trifluoromethyl-2-pyridyl)-4-phenylsulphonylbutanoic acid 12-(n-methyl-n-{7-nitrobenz-2-oxa-1,3-diazol-4-y!])-aminododecanoic acid 3,4,5-triethoxybenzoic acid 2-methoxypropionic acid (r)-(+)-2-methyiglutaric acid boc-10-aminodecanoic acid cis-aconitic acid n(alpha)-fmoc-n(beta)-alloc-1-2,3-diaminopropionic acid 3-(4-butoxy-benzoylamino)-benzoic acid 4.6-dihydroxy-5-methanesulfonyi-1-ph-3a,6-methano-azulene-3-carboxylic acid 2-bromo-angelica acid dodecanedioic acid 2,3 4-trifluorophenylacetic acid (3-methoxystyryl)glyoxylic acid 4-[[(3-hydroxy-2-naphthalenyl)carbonyl]amino benzoic acid 2-benzyl-3-phenyl-propionic acid 2-hydroxydodecanoic acid 2.3-dibromo-2-methyl-propionic acid 8-hydroxy-1-naphthylamine-4.6-disulfonic acid 3.4-dihydroxyphenylacetic acid 2,5-dimethyl-4-(ethoxycarbonyl)-3-furoic acid 4-((5-bromo-1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-amino)-benzoic acid n-carbobenzyloxy-2-methylalanine (3.4-dichloro-benzoylamino)-acetic acid 5-tert-butyl-2-furoic acid 2-hydroxy-3(s)-(n-tert-boc-amino)-hexanoic acid cyclohexanepentanoic acid 2'-nitrophthalanilic acid 5-methoxy-3-methyl-phthalic acid ricinelaidic acid 2-o0x0-6-pentyl-2h-pyran-3-carboxylic acid 2-carboxyamino-3-(2-hydroxy-phenyl)-acrylic acid 2-acetamido-5-nitrobenzoic acid 3-(n-phenylcarbamoyl)-5-norbornene-2-carboxylic acid dl-mandelic acid 3-fluoranthen-1-yl-acrylic acid
2-(4-bromophenyl)-3-(4-chlorobenzoyl)propionic acid 3-methyl-2-furoic acid (2-methylphenoxy)acetic acid (4-methanesulfonyloxy-3-methoxy-phenyl)-acetic acid 2-hydroxy-3-isopropyl-6-methylbenzoic acid 4-(5,6,7,8-tetrahydro-naphthalen-2-yl)-butyric acid 3-benzoylacrylic acid 4-ethoxybenzoic acid (4-hydroxy-3-methoxy-phenyl)-oxo-acetic acid ’ > 2-((5-bromo-1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-amino)-benzoic acid 3-[[(1-acetyl-2,3-dihydro-(1h)-indol-7-yl)amino]carbonyl]propanoic acid 5-methyl-4-oxohexanoic acid (8-ho-3-meo-1,5,9.9-tetra-me-4,12-dioxo-benzocyclodecen-2-ylidene)-acetic acid : 1-(4-fluoroanilino)-6-methyl-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid
T. : n-alpha-(9-fluorenylmethyloxycarbonyl)-[3s]-1,2,3,4-tetrahyd roisoquinoline-7-hydroxy-3- . carboxylic acid 2 2-[(adamantane-1-carbonyl)-amino]-3-(1h-indol-3-yl)-propionic acid n-cbz-dl-aspartic acid carboxymethylmercaptosuccinic acid 3-bromo-4,5-dimethoxybenzoic acid 3 4-dichloroadipic acid 3'-bromophthalanilic acid 6-methylpyrid-3-ylacetic acid 3,5,6-trichlorooctafluorohexanoic acid 3-(5-(4-chloro-phenyl)-furan-2-yl)-acrylic acid epsilon-maleimidocaproic acid 6-(acetoxymethyl)-3-methyl-3-cyclohexene- 1-carboxylic acid phenylsulphonylacetic acid 2-methyl-2-phenyl-octanoic acid 2,5-dibromoadipic acid 1,1-cyclohexanedicarboxylic acid
2-methyl-bicyclo(2.2.1)hept-5-ene-2-carboxylic acid 2'-methyl-5'-nitromaleanilic acid 2-[benzyl-(toluene-4-sulfonyl)-amino]-benzoic acid (carboxy-phenyl-methylsulfanyl)-phenyl-acetic acid indolizine-2-carboxylic acid alpha-methylhydrocinnamic acid 10-methylundecanoic acid alpha-cyano-beta-methyl-2-(methylthio)cinnamic acid 3-hydroxypropanesulfonic acid 2-[[2-(2,4-dichlorophenyl)hydrazino]carbonyl]benzoic acid 5-iodoorotic acid p-bromophenoxy acetic acid 2-hexynoic acid 2'-chloro-3'-(trifluoromethyl)glutaranilic acid
S-methyl-2-phenylimidazo[1,2-a]pyridine-3-carboxylic acid 4-(3-chloropropoxy)-benzoic acid 4-(4,4-dimethyl-2-oxocyclohexyl)butyric acid 2-methyl-5-nitro-3-furoic acid n-methyl-d-aspartic acid 4-hydroxyphenoxyacetic acid chloroacetic acid 4'-nitroglutaranilic acid (2s)-alpha-methylglutamic acid 9(s)-hydroxyoctadeca-10e, 12z-dienoic acid 2-sulfino-benzoic acid 3-(difluoromethoxy)phenylacetic acid 10-oxopalmitic acid 3-benzamidobenzoic acid hippuric acid phenyl s acid 2,7-di-tert-butyl-9,9-dimethyl-4,5-xanthenedicarboxylic acid
5-chloro-2-nitrocinnamic acid delta-n-oxalyl-d-alpha,delta-diaminopentanoic acid : 4'-pentyl-biphenyl-4-carboxylic acid n-(1-naphthyl)glutaramic acid 3'-fluorophthalanilic acid : tricosanoic acid 4-chloro-2,5-difluorobenzoic acid 16-phenyl-hexadecanoic acid : 3-[(r,s)-2-carboxypiperazin-4-yl|propyl-1-phosphonic acid : 2-naphthalen-2-yl-1,3-dioxo-2,3-dihydro- 1 h-isoindole-5-carboxylic acid 2-pyridin-2-yl-quinoline-4-carboxylic acid - 2-(4-methyl-benzoylamino)-3-(4-nitro-phenyl)-acrylic acid dihydroxychicago acid 4-fluoro-3-(trifluoromethyl)phenylacetic acid 2 tolidine, 3,3 disulfonic acid 2-((2-hydroxy-5-methoxy-benzylidene)-amino)-benzoic acid ps 3',4'-dichloroglutaranilic acid 4-(3-dodecanoyl-2-thioureido)benzoic acid 4-hydroxycyclohexanecarboxylic acid 3,5-dihydroxy-4-methoxybenzoic acid (s)-(+)-citramalic acid 2-naphthylamine-3.6.8-trisulfonic acid 3,5-ditodo-4-hydroxyphenylpropionic acid (s)-(-)-2-bromo 3-methylbutanoic acid (r)-(-)-2-phenylbutyric acid fluorene-4-carboxylic acid n-(2-carboxyphenyl)glycine 2-methoxy-3.6-dichlorobenzoic acid 7-bromokynurenic acid 2-naphthylamine-3.6.8-trisulfonic acid n-tert-butylsuccinamic acid

Claims (14)

1. A paroxetine salt of an acid selected from the Group of Acids.
2. A salt according to claim 1 which is a salt with a D-acid
3. A salt according to claim 1 which is a salt with a L-acid
4. A salt according to claim 1, 2 or 3 in which the ratio of paroxetine free base to acid (by mole) is 1:1.
5. A salt according to claim 1, 2 or 3 in which the ratio of paroxetine free base to acid (by mole) 1s 2:1.
6. A compound according to claim 1, 2, 3, 4 or 5 in non-crystalline form.
7. A compound according to claim 1, 2, 3, 4 or 5 in crystalline form.
8. A process for the preparation of a compound as claimed in claim 1, 2,3, 4, 5S or 6 by precipitation from a solution of the paroxetine salt, spray drying or freeze drying a solution of the paroxetine salt. evaporating a solution of the paroxetine salt to a glass, or by vacuum drying of oils of the paroxetine salt, or solidification of melts of the paroxetine salt.
9. A process for the preparation of a compound as claimed in claim 1,2, 3,4, 5or 7 by crystallization or re-crystallization from a solution of the paroxetine salt.
10. A process according to claim 8 or 9 in which the solution, oil or melt of the paroxetine salt is prepared by treating paroxetine free base or an organic acid salt thereof with an acid selected from the Group of Acids or an ammonium or amine salt thereof.
/ 11. Use of a salt of paroxetine with an acid selected from the Group of Acids in the manufacture of a medicament for treating and/or preventing any one or more of the Disorders.
12. A salt of paroxetine with an acid selected from the Group of Acids, for use in treating and/or preventing any one of the Disorders.
13. A salt according to claim 1, substantially as herein described and exemplified.
14. A process according to claim 8 or 9, substantially as herein described and exemplified. AMENDED SHEET
ZA200100020A 1998-07-02 2001-01-02 Salts of paroxetine. ZA200100020B (en)

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