YU75295A - A FACTOR THAT STIMULATES THE HUMAN COLONY OF GRANULocytes - Google Patents
A FACTOR THAT STIMULATES THE HUMAN COLONY OF GRANULocytesInfo
- Publication number
- YU75295A YU75295A YU75295A YU75295A YU75295A YU 75295 A YU75295 A YU 75295A YU 75295 A YU75295 A YU 75295A YU 75295 A YU75295 A YU 75295A YU 75295 A YU75295 A YU 75295A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- csf
- colony
- granulocytes
- stimulates
- study
- Prior art date
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
FAKTOR KOJI STIMULIŠE HUMANU KOLONIJU GRANULOCITA - prema pronalasku, pripada oblasti molekularne biologije, a odnosi se na humani hromozomski kodirajući gen za polipeptid koji poseduje aktivnost faktora stimulisanja kolonije (označen kao CSF) koji je specifični stimulirajući faktor potreban principijelno za građenje kolonija humanih granulocitnih ćelija. Pronalazak se odnosi i na rekombinantni vektor prisutan u pomenutom genu, transformant koji sadrži pomenuti vektor i postupak za dobijanje glikoproteina koji ima CSF aktivnost. Razjašnjavanje pojedinih CSF podklasa i pravljenje studijanjihovih hemijskih i bioloških osobina je vrlo važno za proučavanje hematopoietskih mehanizama i analiziranje patomorfoloških aspekata raznih hematoloSkih oboljenja. Biološka dejstva G-CSF izazivaju uvećanu pažnju istraživača zbog svoje sposobnosti izazivanja diferencijacije leukemijskih ćelija koStane srži i pojačavanja funkcija zrelih granulocita, i potencijalno pruža mogućnost uspešne kliničke primene u oblastima tretiranja i prevencije leukemije. Prijava je izdvojena iz jugoslovenske patentne prijave P-1610/86.FACTORS WHICH STIMULATES THE HUMAN COLONY OF GRANULOCYTES - according to the invention, belongs to the field of molecular biology, and refers to a human chromosomal coding gene for a polypeptide having the activity of a colony stimulating factor (referred to as CSF), which is a specific stimulating factor required in principle for the construction of colony cells. The invention also relates to a recombinant vector present in said gene, a transformant comprising said vector, and a method for producing a glycoprotein having CSF activity. The elucidation of individual CSF subclasses and the study of their chemical and biological properties is very important for the study of hematopoietic mechanisms and for the analysis of the pathomorphological aspects of various hematological diseases. The biological effects of G-CSF have attracted increased research attention due to their ability to induce bone marrow differentiation of leukemia cells and enhance the function of mature granulocytes, and potentially offer the potential for successful clinical applications in leukemia treatment and prevention. The application was isolated from the patent application P-1610/86 of Yugoslavia.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU75295A YU48523B (en) | 1985-09-30 | 1995-12-04 | Human granulocyte colony stimulating factor |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21715085 | 1985-09-30 | ||
JP61166709A JPH0657152B2 (en) | 1985-09-17 | 1986-07-17 | CSF genes |
JP61166710A JPS62236497A (en) | 1985-09-17 | 1986-07-17 | Novel glycoprotein and production thereof |
YU161086A YU48546B (en) | 1985-10-25 | 1986-09-16 | Human granulocyte colony stimulating factor |
YU75295A YU48523B (en) | 1985-09-30 | 1995-12-04 | Human granulocyte colony stimulating factor |
Publications (2)
Publication Number | Publication Date |
---|---|
YU75295A true YU75295A (en) | 1997-07-31 |
YU48523B YU48523B (en) | 1998-11-05 |
Family
ID=47566346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU75295A YU48523B (en) | 1985-09-30 | 1995-12-04 | Human granulocyte colony stimulating factor |
Country Status (1)
Country | Link |
---|---|
YU (1) | YU48523B (en) |
-
1995
- 1995-12-04 YU YU75295A patent/YU48523B/en unknown
Also Published As
Publication number | Publication date |
---|---|
YU48523B (en) | 1998-11-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Binderman et al. | Formation of bone tissue in culture from isolated bone cells | |
KR860700264A (en) | Lymphokine Production and Purification | |
YU46597B (en) | PROCEDURE FOR THE PRODUCTION OF HYBRID INTERFERONS OF HUMAN LEUKOCYTES | |
ATE192500T1 (en) | RECOMBINANT VIRUS VECTORS FOR EXPRESSION IN MUSCLE CELLS | |
FI20010334A (en) | Granulocyte Colonization Stimulating Polypeptides, Pharmaceutical Composition Containing Them, and Their Medical Use | |
YU47700B (en) | INTERFERONS AND PROCEDURES FOR OBTAINING THEM | |
DK1131422T3 (en) | Recombinant glycoproteins, methods for their preparation, drugs containing them and their use | |
RU95110767A (en) | Dna encoding human glycoprotein | |
GR3025718T3 (en) | Progenitor b cell stimulating factor. | |
DE3683430D1 (en) | A HUMAN GRANULOCYT COLONIZING FACTOR FOR THE TREATMENT OF LEUKOPENIA PHARMACEUTICAL PREPARATION. | |
CA2087170A1 (en) | Promotion of maturation of hematopoietic progenitor cells | |
ES2039209T3 (en) | PHARMACEUTICAL AGENT CONTAINING A HUMAN GRANULOCYTIC COLONY STIMULATION FACTOR. | |
US9410143B1 (en) | Biological molecules produced by electromagnetically stimulating living mammalian cells | |
Metcalf | Sources and biology of regulatory factors active on mouse myeloid leukeimic cells | |
YU75295A (en) | A FACTOR THAT STIMULATES THE HUMAN COLONY OF GRANULocytes | |
IL88034A0 (en) | Mutant acidic fibroblast growth factor,its preparation and pharmaceutical compositions containing it | |
EP0607593B1 (en) | Process for obtaining cell cultures with higher content of autologous cytokines | |
EP0516845A4 (en) | Novel megakaryocytic colony stimulating factor and process for its preparation. | |
Denburg et al. | Factors influencing basophilic differentiation of HL-60 cells | |
MURAO et al. | RECOMBINANT GAMMA-INTERFERON AND LIPOPOLYSACCHARIDE ENHANCE 1, 25-DIHYDROXYVITAMIN D3-INDUCED CELLD IFFERENTIATION IN HUMAN PROMYELOCYTIC LEUKEMIA (HL-60) CELLS | |
MIYOSHI et al. | Large-Scale production of human interferon by leukemic lymphoblasts grown in hamsters | |
Udupa et al. | The pattern of myeloid suppression and recovery after the addition of methotrexate to murine long-term bone marrow culture | |
Tawhid et al. | Cooperative effects of human recombinant granulocyte-macrophage colony stimulating factor and human recombinant erythropoietin in inducing erythroid differentiation of the human erythroleukaemia cell line K 562 clonogenic cells | |
Zhdanov et al. | Role of Thy 1.2+ cells in hemopoietic regulation in cytostatic-induced hemosuppression | |
KR880701249A (en) | New protein, neuroleukin |