YU58979A - Process for producing antiinflammatory 4,5-diaryl-2-(substituted-thio)-pyrroles and corresponding sulfoxides and sulfones thereof - Google Patents
Process for producing antiinflammatory 4,5-diaryl-2-(substituted-thio)-pyrroles and corresponding sulfoxides and sulfones thereofInfo
- Publication number
- YU58979A YU58979A YU00589/79A YU58979A YU58979A YU 58979 A YU58979 A YU 58979A YU 00589/79 A YU00589/79 A YU 00589/79A YU 58979 A YU58979 A YU 58979A YU 58979 A YU58979 A YU 58979A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- pyrroles
- sulfones
- diaryl
- thio
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88633778A | 1978-03-13 | 1978-03-13 | |
| US97220178A | 1978-12-28 | 1978-12-28 | |
| US1025979A | 1979-02-08 | 1979-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU58979A true YU58979A (en) | 1983-04-30 |
Family
ID=27359191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU00589/79A YU58979A (en) | 1978-03-13 | 1979-03-12 | Process for producing antiinflammatory 4,5-diaryl-2-(substituted-thio)-pyrroles and corresponding sulfoxides and sulfones thereof |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0005156B1 (pt) |
| JP (1) | JPS54141766A (pt) |
| AR (2) | AR225739A1 (pt) |
| AU (1) | AU527243B2 (pt) |
| CA (1) | CA1126275A (pt) |
| DE (1) | DE2963707D1 (pt) |
| DK (1) | DK75779A (pt) |
| ES (2) | ES478556A1 (pt) |
| FI (1) | FI790852A (pt) |
| GR (1) | GR66513B (pt) |
| IL (1) | IL56856A (pt) |
| MX (1) | MX5685E (pt) |
| NO (1) | NO790821L (pt) |
| NZ (1) | NZ189881A (pt) |
| PH (1) | PH14378A (pt) |
| PT (1) | PT69336A (pt) |
| YU (1) | YU58979A (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4267184A (en) * | 1979-02-08 | 1981-05-12 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones |
| DK350280A (da) * | 1979-08-27 | 1981-02-28 | Du Pont | Fremgangsmaade til fremstilling af 4,5-diaryl-alfapolyfluoralkyl-1h-pyrrol-2-methanoler og 1-(4,5-diaryl-1h-pyrrol-2-yl)-polyfluoralkanoner |
| US4267190A (en) * | 1980-04-18 | 1981-05-12 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α,α-bis(polyfluoromethyl)-1H-pyrrole-2-methanethiols |
| EP0044485A1 (en) * | 1980-07-21 | 1982-01-27 | E.I. Du Pont De Nemours And Company | Antiinflammatory 2,3-diaryl-5(2,2,2-trifluoro-1-(trifluoromethyl)-ethyl)-1H-pyrroles |
| DE3317653A1 (de) * | 1983-05-14 | 1984-11-15 | Gödecke AG, 1000 Berlin | 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende |
| US5306827A (en) * | 1991-12-04 | 1994-04-26 | American Cyanamid Company | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents |
| US5492925A (en) * | 1993-08-31 | 1996-02-20 | American Cyanamid Company | Thienyl-and furylpyrrole insecticidal and acaricidal agents |
| FR2874012B1 (fr) * | 2004-08-09 | 2008-08-22 | Sanofi Synthelabo | Derives de pyrrole, leur preparation et leur utlisation en therapeutique |
| US8822694B2 (en) | 2009-02-25 | 2014-09-02 | Takeda Pharmaceutical Company Limited | Process for producing pyrrole compound |
-
1979
- 1979-02-21 DK DK75779A patent/DK75779A/da not_active Application Discontinuation
- 1979-03-09 PH PH22271A patent/PH14378A/en unknown
- 1979-03-12 YU YU00589/79A patent/YU58979A/xx unknown
- 1979-03-12 MX MX797806U patent/MX5685E/es unknown
- 1979-03-12 DE DE7979100736T patent/DE2963707D1/de not_active Expired
- 1979-03-12 GR GR58568A patent/GR66513B/el unknown
- 1979-03-12 IL IL56856A patent/IL56856A/xx unknown
- 1979-03-12 PT PT69336A patent/PT69336A/pt unknown
- 1979-03-12 NO NO790821A patent/NO790821L/no unknown
- 1979-03-12 EP EP79100736A patent/EP0005156B1/en not_active Expired
- 1979-03-12 CA CA323,172A patent/CA1126275A/en not_active Expired
- 1979-03-12 ES ES478556A patent/ES478556A1/es not_active Expired
- 1979-03-12 NZ NZ189881A patent/NZ189881A/xx unknown
- 1979-03-13 AU AU45040/79A patent/AU527243B2/en not_active Ceased
- 1979-03-13 FI FI790852A patent/FI790852A/fi not_active Application Discontinuation
- 1979-03-13 AR AR275794A patent/AR225739A1/es active
- 1979-03-13 JP JP2926779A patent/JPS54141766A/ja active Pending
- 1979-09-14 ES ES484196A patent/ES484196A1/es not_active Expired
-
1980
- 1980-10-16 AR AR282895A patent/AR224276A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| NO790821L (no) | 1979-09-14 |
| DE2963707D1 (en) | 1982-11-04 |
| DK75779A (da) | 1979-09-14 |
| PH14378A (en) | 1981-06-17 |
| CA1126275A (en) | 1982-06-22 |
| ES478556A1 (es) | 1979-12-16 |
| AR225739A1 (es) | 1982-04-30 |
| PT69336A (en) | 1979-04-01 |
| MX5685E (es) | 1983-12-09 |
| IL56856A (en) | 1982-09-30 |
| FI790852A (fi) | 1979-09-14 |
| AU4504079A (en) | 1979-09-20 |
| AR224276A1 (es) | 1981-11-13 |
| AU527243B2 (en) | 1983-02-24 |
| EP0005156A1 (en) | 1979-11-14 |
| ES484196A1 (es) | 1980-05-16 |
| GR66513B (pt) | 1981-03-24 |
| NZ189881A (en) | 1981-02-11 |
| JPS54141766A (en) | 1979-11-05 |
| IL56856A0 (en) | 1979-05-31 |
| EP0005156B1 (en) | 1982-09-22 |
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