YU46099B - PROCESS FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- 1-PIPERAZINYL) -1 - Google Patents

PROCESS FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- 1-PIPERAZINYL) -1

Info

Publication number
YU46099B
YU46099B YU244787A YU244787A YU46099B YU 46099 B YU46099 B YU 46099B YU 244787 A YU244787 A YU 244787A YU 244787 A YU244787 A YU 244787A YU 46099 B YU46099 B YU 46099B
Authority
YU
Yugoslavia
Prior art keywords
piperazinyl
oxo
fluoro
substituted
preparing
Prior art date
Application number
YU244787A
Other languages
Serbo-Croatian (sh)
Other versions
YU244787A (en
Inventor
M. Globokar
N. Zupančič
B. Šket
P. Zupet
M. Zupan
Original Assignee
Krka Tovarna Zdravil
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Tovarna Zdravil filed Critical Krka Tovarna Zdravil
Priority to YU244787A priority Critical patent/YU46099B/en
Priority to SI8712447A priority patent/SI8712447A8/en
Priority to NO88885666A priority patent/NO885666L/en
Priority to PT8935988A priority patent/PT89359B/en
Priority to CS903288A priority patent/CS274635B2/en
Priority to AT320688A priority patent/AT396105B/en
Priority to PL27689088A priority patent/PL163337B1/en
Priority to HU667788A priority patent/HU200454B/en
Priority to SU4613227 priority patent/RU2002744C1/en
Priority to DD32470388A priority patent/DD283386B5/en
Publication of YU244787A publication Critical patent/YU244787A/en
Publication of YU46099B publication Critical patent/YU46099B/en
Priority to LTIP510A priority patent/LT3274B/en
Priority to LV930828A priority patent/LV10774B/en
Priority to HRP-2447/87A priority patent/HRP931142A2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

4-DIHID ROKINOLIN-3-KARBOKSILNE KISLINE IN NOV INTERMEDIAT UPORABEN V TEM POSTOPKU, s formulo I v kateri pommeni R CH2CH3, ciklopropil, CH2CH2OH, CH2OCH2CH2OH, označen s tem, da 1-substituirano 6-fluoro-4-okso-7-(4-karboetoksi-1-piperazinil)-1,4-dihidrokinolin-3-karboksilno kislino oz. njen etil ester s splošno formulo II v kateri ima R enak pomen kot zgoraj, R pa pomeni vodik ali etil, hidroliziramo v bazičnem mediju. Prijava vsebuje še 4 zahtevke.ROCKINOLIN-3-CARBOXYLIC ACID 4-DIHYDE AND A NEW INTERMEDIATE USED IN THIS PROCESS, of formula I wherein R is CH2CH3, cyclopropyl, CH2CH2OH, CH2OCH2CH2OH, characterized in that 1-substituted 6-oxo-4-fluoro-4 (4-Carboethoxy-1-piperazinyl) -1,4-dihydroquinoline-3-carboxylic acid or its ethyl ester of general formula II in which R has the same meaning as above and R represents hydrogen or ethyl is hydrolysed in a basic medium. The application contains 4 more claims.

YU244787A 1987-12-31 1987-12-31 PROCESS FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- 1-PIPERAZINYL) -1 YU46099B (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
YU244787A YU46099B (en) 1987-12-31 1987-12-31 PROCESS FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- 1-PIPERAZINYL) -1
SI8712447A SI8712447A8 (en) 1987-12-31 1987-12-31 Process for preparing 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl) -1,4-dihydroquinoline-3-carboxylic acid and new intermediate used in this process
NO88885666A NO885666L (en) 1987-12-31 1988-12-21 PROCEDURE FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- (1-PIPERAZINYL) -1,4-DIHYDROQINOLINE-3-CARBOXYLIC ACID AND INTERMEDIATE PRODUCT FOR USE IN THE PROCEDURE.
PT8935988A PT89359B (en) 1987-12-31 1988-12-28 6-FLUOR-4-OXO-7- (1-PIPERAZINYL) -1,4-DIHYDROQUINOLINE-3-CARBOXYLIC-1-SUBSTITUTED ACIDS AND NEW INTERMEDIATE COMPOUNDS USED IN THIS PROCESS
CS903288A CS274635B2 (en) 1987-12-31 1988-12-29 Method of 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxyl acid preparation
HU667788A HU200454B (en) 1987-12-31 1988-12-30 Process for production of derivatives of 1-substituated-6-fluor-4-oxo-7-/1-piperasinile/-1,4-dihydro-quinoline-3-carbonic acid
PL27689088A PL163337B1 (en) 1987-12-31 1988-12-30 Method of obtaining derivatives of 6-fluoro-4-keto-7-/piperazine-1/-1,4-dihydroquinoline carboxylic-3 acid
AT320688A AT396105B (en) 1987-12-31 1988-12-30 Process for the preparation of 1-substituted 6-fluoro-4- oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid and novel intermediate which can be used in this process
SU4613227 RU2002744C1 (en) 1987-12-31 1988-12-30 Method of synthesis of 1-substituted 6-fluoro-4-oxo-7-(1- piperazinyl)-1,4- -dihydroquinoline-3-carboxylic acid
DD32470388A DD283386B5 (en) 1987-12-31 1988-12-30 Process for the preparation of 1-substituted 6-fluoro-4-oxo-7- (1-piperazinyl) -1,4-dihydroquinoline-3-carboxylic acid
LTIP510A LT3274B (en) 1987-12-31 1993-05-05 Process for preparing 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid
LV930828A LV10774B (en) 1987-12-31 1993-06-30 Process for preparation of 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid, 6-fluoro-4-oxo-7-(4-carbethoxy-1-piperazinyl)-1,4-dihydroquinoline-3-ethylcarboxylate and method for preparing thereof
HRP-2447/87A HRP931142A2 (en) 1987-12-31 1993-08-19 Process for the preparation of 1-substituted 6-floro-4-oxo-7-(1-piperazinyl)-1,4-dihydrquinoline-3-carbonic acid and new intermediate used in this process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU244787A YU46099B (en) 1987-12-31 1987-12-31 PROCESS FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- 1-PIPERAZINYL) -1

Publications (2)

Publication Number Publication Date
YU244787A YU244787A (en) 1990-06-30
YU46099B true YU46099B (en) 1992-12-21

Family

ID=25557985

Family Applications (1)

Application Number Title Priority Date Filing Date
YU244787A YU46099B (en) 1987-12-31 1987-12-31 PROCESS FOR PREPARING 1-SUBSTITUTED 6-FLUORO-4-OXO-7- 1-PIPERAZINYL) -1

Country Status (12)

Country Link
AT (1) AT396105B (en)
CS (1) CS274635B2 (en)
DD (1) DD283386B5 (en)
HU (1) HU200454B (en)
LT (1) LT3274B (en)
LV (1) LV10774B (en)
NO (1) NO885666L (en)
PL (1) PL163337B1 (en)
PT (1) PT89359B (en)
RU (1) RU2002744C1 (en)
SI (1) SI8712447A8 (en)
YU (1) YU46099B (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
SE444566B (en) 1977-09-20 1986-04-21 Bellon Labor Sa Roger 7-DIALKYLAMINE-6-HALOGEN-4-OXO-1,4-DIHYDROQINOLINE-3-CARBOXYLIC ACID, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL PREPARATION OF THEREOF
JPS5845426B2 (en) * 1978-09-29 1983-10-08 杏林製薬株式会社 Substituted quinoline carboxylic acid derivatives
JPS5762259A (en) 1980-09-05 1982-04-15 Kyorin Pharmaceut Co Ltd Preparation of substituted quinolinecarboxylic acid derivative
DE3306771A1 (en) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen CHINOLONIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3308909A1 (en) 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen BACTERICIDALS BASED ON CHINOLONIC CARBONIC ACID
DE3509546A1 (en) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-AMINO-1- (SUBST.CYCLOPROPYL) -1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
JPH06103891B2 (en) 1989-05-31 1994-12-14 日本電信電話株式会社 Routing method for packet switching network
JPH066686A (en) 1992-06-17 1994-01-14 Ricoh Co Ltd Image pickup device

Also Published As

Publication number Publication date
CS274635B2 (en) 1991-09-15
SI8712447A8 (en) 1995-12-31
ATA320688A (en) 1992-10-15
PL276890A1 (en) 1989-10-16
LV10774A (en) 1995-08-20
LV10774B (en) 1996-08-20
RU2002744C1 (en) 1993-11-15
PT89359B (en) 1993-08-31
LT3274B (en) 1995-05-25
DD283386B5 (en) 1997-10-30
HUT49129A (en) 1989-08-28
HU200454B (en) 1990-06-28
NO885666D0 (en) 1988-12-21
AT396105B (en) 1993-06-25
CS903288A2 (en) 1990-12-13
NO885666L (en) 1989-07-03
PT89359A (en) 1989-12-29
LTIP510A (en) 1994-11-25
YU244787A (en) 1990-06-30
PL163337B1 (en) 1994-03-31

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