YU391A - BIOMASS FOR VIRUS / VIRUS ANTIGEN PRODUCTION - Google Patents

BIOMASS FOR VIRUS / VIRUS ANTIGEN PRODUCTION

Info

Publication number
YU391A
YU391A YU391A YU391A YU391A YU 391 A YU391 A YU 391A YU 391 A YU391 A YU 391A YU 391 A YU391 A YU 391A YU 391 A YU391 A YU 391A
Authority
YU
Yugoslavia
Prior art keywords
virus
biomass
production
antigen production
virus antigen
Prior art date
Application number
YU391A
Other languages
Serbo-Croatian (sh)
Inventor
W. Mundt
W. Woehrer
F. Dorner
J. Eibl
Original Assignee
Immuno Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Aktiengesellschaft filed Critical Immuno Aktiengesellschaft
Priority to HRP921353 priority Critical patent/HRP921353A2/en
Publication of YU391A publication Critical patent/YU391A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24051Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24151Methods of production or purification of viral material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Semiconductor Memories (AREA)
  • Non-Volatile Memory (AREA)

Abstract

Izum se nanaša na biomaso za produkcijo virusa/virusantigena, ki sestoji iz celičnih agregatov s premerom od 100 um do 1000 um. Biomasa v smislu izuma ima v suspenziji medija kulture visoko metabolično aktivnost in je inficirana z virusom. Omogoča produkcijo čistega virusa/virusantigena v velikem tehničnem obsegu in je primerna zlasti za produkcijo FSME-virusa/virusantigena.The invention relates to biomass for virus / virus antigen production consisting of cell aggregates with a diameter of 100 μm to 1000 μm. The biomass according to the invention has a high metabolic activity in the suspension of the culture medium and is infected with a virus. It allows the production of pure virus / virus antigen on a large technical scale and is particularly suitable for the production of FSME virus / virus antigen.

YU391A 1990-01-04 1991-01-03 BIOMASS FOR VIRUS / VIRUS ANTIGEN PRODUCTION YU391A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HRP921353 HRP921353A2 (en) 1990-01-04 1992-11-25 Biomass for the production of viruses/virus antigenes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT18/90A AT393277B (en) 1990-01-04 1990-01-04 METHOD FOR PRODUCING EARLY SUMMER MENINGOENZEPHALITIS VIRUS (TBE VIRUS) ANTIGES

Publications (1)

Publication Number Publication Date
YU391A true YU391A (en) 1994-04-05

Family

ID=3479351

Family Applications (1)

Application Number Title Priority Date Filing Date
YU391A YU391A (en) 1990-01-04 1991-01-03 BIOMASS FOR VIRUS / VIRUS ANTIGEN PRODUCTION

Country Status (17)

Country Link
US (2) US5391491A (en)
EP (1) EP0509008B1 (en)
JP (1) JP2633392B2 (en)
AT (2) AT393277B (en)
CA (1) CA2073168C (en)
CZ (1) CZ279725B6 (en)
DE (1) DE59103696D1 (en)
DK (1) DK0509008T3 (en)
ES (1) ES2067921T3 (en)
FI (1) FI106241B (en)
HR (1) HRP921353A2 (en)
HU (1) HU212597B (en)
NO (1) NO310472B1 (en)
RU (1) RU2099419C1 (en)
SK (1) SK279200B6 (en)
WO (1) WO1991009937A1 (en)
YU (1) YU391A (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719051A (en) * 1989-12-22 1998-02-17 Immuno Aktiengesellschaft Perfusion system and a method for the large scale production of virus or virus antigen
AT393277B (en) * 1990-01-04 1991-09-25 Immuno Ag METHOD FOR PRODUCING EARLY SUMMER MENINGOENZEPHALITIS VIRUS (TBE VIRUS) ANTIGES
US5753489A (en) * 1994-11-10 1998-05-19 Immuno Ag Method for producing viruses and vaccines in serum-free culture
US5698433A (en) * 1994-11-10 1997-12-16 Immuno Ag Method for producing influenza virus and vaccine
US5756341A (en) * 1994-11-10 1998-05-26 Immuno Ag Method for controlling the infectivity of viruses
DE69535940D1 (en) 1994-11-10 2009-06-04 Baxter Healthcare Sa Process for the production of biological products in protein-free culture
US6146873A (en) * 1994-11-10 2000-11-14 Baxter Aktiengesellschaft Production of orthomyxoviruses in monkey kidney cells using protein-free media
DE19612966B4 (en) 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK cells and methods of propagating influenza viruses
BR9804283B1 (en) * 1998-03-18 2010-11-30 process for producing low density flaviviruses from cultured cells and process for producing low density recombinant flaviviruses from cultured cells.
US7445924B2 (en) * 2000-11-23 2008-11-04 Bavarian Nordic A/S Modified Vaccinia Ankara virus variant and cultivation method
DE10144906B4 (en) 2001-09-12 2013-11-28 Novartis Vaccines And Diagnostics Gmbh Process for the large-scale production of vaccines
US20040023358A1 (en) * 2001-12-21 2004-02-05 Wyeth Avian embryo particulate biomass for the production of virus antigens
PT1434858E (en) * 2002-09-05 2008-07-28 Bavarian Nordic As Method for the amplification of a poxvirus under serum free conditions
US7998488B2 (en) 2008-11-14 2011-08-16 Baxter International Inc. Vaccine formulations and uses thereof
AU2011305348A1 (en) 2010-09-23 2013-04-18 Baxter Healthcare Sa Recombinant viral vectors and methods for inducing an immune response to yellow fever virus
CN103458922B (en) 2011-01-31 2017-10-03 纳米医疗公司 Recombinant viral vector and method of the induction to the heterologous hypotype immune response of influenza A virus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4059485A (en) * 1976-11-03 1977-11-22 Monsanto Company Adaptation of cell lines to suspension culture
US4195130A (en) * 1978-04-20 1980-03-25 Cornell Research Foundation, Inc. Propagation of feline infectious peritonitis virus in tissue cultures
AT358167B (en) * 1978-12-22 1980-08-25 Immuno Ag METHOD FOR PRODUCING EARLY SUMMER MENINGOENZEPHALITIS VIRUS (FSME VIRUS) VACCINES
US4335215A (en) * 1980-08-27 1982-06-15 Monsanto Company Method of growing anchorage-dependent cells
AT393277B (en) * 1990-01-04 1991-09-25 Immuno Ag METHOD FOR PRODUCING EARLY SUMMER MENINGOENZEPHALITIS VIRUS (TBE VIRUS) ANTIGES
US5114855A (en) * 1990-04-19 1992-05-19 Regents Of The University Of Minnesota Method for aggregating cells with small microspheres

Also Published As

Publication number Publication date
HUT64583A (en) 1994-01-28
HU212597B (en) 1996-08-29
JP2633392B2 (en) 1997-07-23
WO1991009937A1 (en) 1991-07-11
NO922622D0 (en) 1992-07-02
CZ279725B6 (en) 1995-06-14
EP0509008A1 (en) 1992-10-21
CS9100012A2 (en) 1991-08-13
HRP921353A2 (en) 1995-10-31
RU2099419C1 (en) 1997-12-20
EP0509008B1 (en) 1994-11-30
FI923099A0 (en) 1992-07-03
US5391491A (en) 1995-02-21
AT393277B (en) 1991-09-25
CA2073168C (en) 1999-04-27
US5550051A (en) 1996-08-27
ATE114713T1 (en) 1994-12-15
DK0509008T3 (en) 1995-04-18
NO922622L (en) 1992-07-23
SK279200B6 (en) 1998-07-08
FI923099A (en) 1992-07-03
FI106241B (en) 2000-12-29
ES2067921T3 (en) 1995-04-01
DE59103696D1 (en) 1995-01-12
JPH05503843A (en) 1993-06-24
NO310472B1 (en) 2001-07-09
ATA1890A (en) 1991-02-15
CA2073168A1 (en) 1991-07-05

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