YU29596A - Genski proizvodi koji regulišu gojaznost - Google Patents
Genski proizvodi koji regulišu gojaznostInfo
- Publication number
- YU29596A YU29596A YU29596A YU29596A YU29596A YU 29596 A YU29596 A YU 29596A YU 29596 A YU29596 A YU 29596A YU 29596 A YU29596 A YU 29596A YU 29596 A YU29596 A YU 29596A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- leu
- xaa
- ser
- val
- gin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Protein formule I: (SEQ ID BR: 1) Val Pro He Xaa Xaa Val Gin Asp Asp Thr Lys Thr Leu lie 1 5 10 Lys Thr lie Val Thr Arg lie Xaa Asp lie Ser His Xaa Xaa 15 20 25 Ser Val Ser Ser Lys Gin Arg Val Thr Gly Leu Asp Phe He 30 35 40 Pro Gly Leu His Pro Xaa Leu Ser Leu Ser Lys Met Asp Gin 45 50 ,j 55 Thr Leu Ala lie Tyr Gin Gin He Leu Thr Ser Leu Pro Ser 60 65 70 Arg Asn Val Xaa Gin He Ser Asn Asp Leu Glu Asn Leu Arg 75 80 Asp Leu Leu His Leu Leu Ala Xaa Ser Lys Ser Cys Pro 85 90 95 Leu Pro Gin Xaa Arg Ala Leu Glu Xaa Leu Glu Ser Leu 100 105 110 Gly Xaa Val Leu Glu Ala Ser Leu Tyr Ser Thr Glu Val Val 115 120 Ala Leu Ser Arg Leu Gin Gly Xaa Leu Gin Asp ft/let Leu 125 130 135 Arg Gin Leu Asp Leu Ser Pro Gly Cys 140 145 u kojoj: Xaa na poziciji 4 je Trp ili Cys; Xaa na poziciji 5 je Lys ili Arg; Xaa na poziciji 22 je Ser ili Asn; jxP Xaa na poziciji 27 je Met ili Thr; Xaa na poziciji 28 je Gin ili je odsutan; Xaa na poziciji 48 je Val ili Leu; Xaa na poziciji 74 je lie ili Val; Xaa na poziciji 92 je Ser ili Ala; Xaa na poziciji 101 je Ala ili Val; Xaa na poziciji 106 je Thr ili Ser; Xaa na poziciji 112 je Gly ili Val; i Xaa na poziciji 132 je Ala ili Ser; ili njihova farmaceutski prihvatljiva so.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44530595A | 1995-05-19 | 1995-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU29596A true YU29596A (sh) | 1998-07-10 |
Family
ID=23768399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU29596A YU29596A (sh) | 1995-05-19 | 1996-05-16 | Genski proizvodi koji regulišu gojaznost |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0743321A3 (sh) |
| JP (1) | JPH11505706A (sh) |
| AR (1) | AR002742A1 (sh) |
| AU (1) | AU5795496A (sh) |
| CA (1) | CA2221303A1 (sh) |
| IL (1) | IL118297A0 (sh) |
| PE (1) | PE50997A1 (sh) |
| WO (1) | WO1996036644A1 (sh) |
| YU (1) | YU29596A (sh) |
| ZA (1) | ZA963915B (sh) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6350730B1 (en) | 1994-08-17 | 2002-02-26 | The Rockefeller University | OB polypeptides and modified forms as modulators of body weight |
| US6001968A (en) | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
| US6471956B1 (en) | 1994-08-17 | 2002-10-29 | The Rockefeller University | Ob polypeptides, modified forms and compositions thereto |
| US6429290B1 (en) | 1994-08-17 | 2002-08-06 | The Rockefeller University | OB polypeptides, modified forms and derivatives |
| US6124448A (en) * | 1994-08-17 | 2000-09-26 | The Rockfeller University | Nucleic acid primers and probes for the mammalian OB gene |
| US6048837A (en) * | 1994-08-17 | 2000-04-11 | The Rockefeller University | OB polypeptides as modulators of body weight |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US6225446B1 (en) | 1995-12-06 | 2001-05-01 | Schering Corporation | Mutational variants of mammalian proteins |
| WO1997020933A2 (en) * | 1995-12-06 | 1997-06-12 | Schering Corporation | MUTATIONAL VARIANTS OF MAMMALIAN Ob GENE PROTEINS |
| EP0784979A3 (en) * | 1996-01-19 | 1999-03-03 | Eli Lilly And Company | Obesity protein formulations |
| WO1997026916A1 (en) * | 1996-01-25 | 1997-07-31 | Eli Lilly And Company | Obesity protein analog compounds and formulations thereof |
| US6001816A (en) * | 1996-06-20 | 1999-12-14 | Merck & Co., Inc. | Gene therapy for leptin deficiency |
| US6277592B1 (en) * | 1996-07-31 | 2001-08-21 | Purina Mills, Inc. | Porcine leptin protein, nucleic acid sequences coding therefor and uses thereof |
| US20020110857A1 (en) * | 1996-07-31 | 2002-08-15 | Spurlock Michael E. | Bovine leptin protein, antisense and antibody |
| US6297027B1 (en) * | 1996-07-31 | 2001-10-02 | Purina Mills, Inc. | Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof |
| US5965521A (en) * | 1997-02-25 | 1999-10-12 | Eli Lilly Company | Pulsatile delivery of leptin receptor ligands |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| WO1996023517A1 (en) * | 1995-01-31 | 1996-08-08 | Eli Lilly And Company | Anti-obesity proteins |
-
1996
- 1996-05-16 AR ARP960102592A patent/AR002742A1/es unknown
- 1996-05-16 IL IL11829796A patent/IL118297A0/xx unknown
- 1996-05-16 PE PE1996000338A patent/PE50997A1/es not_active Application Discontinuation
- 1996-05-16 WO PCT/US1996/007045 patent/WO1996036644A1/en active Search and Examination
- 1996-05-16 YU YU29596A patent/YU29596A/sh unknown
- 1996-05-16 JP JP8535053A patent/JPH11505706A/ja active Pending
- 1996-05-16 CA CA002221303A patent/CA2221303A1/en not_active Abandoned
- 1996-05-16 EP EP96303478A patent/EP0743321A3/en not_active Withdrawn
- 1996-05-16 AU AU57954/96A patent/AU5795496A/en not_active Abandoned
- 1996-05-16 ZA ZA9603915A patent/ZA963915B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL118297A0 (en) | 1996-09-12 |
| EP0743321A2 (en) | 1996-11-20 |
| WO1996036644A1 (en) | 1996-11-21 |
| EP0743321A3 (en) | 1997-01-15 |
| JPH11505706A (ja) | 1999-05-25 |
| AR002742A1 (es) | 1998-04-29 |
| PE50997A1 (es) | 1997-12-18 |
| CA2221303A1 (en) | 1996-11-21 |
| ZA963915B (en) | 1997-11-17 |
| AU5795496A (en) | 1996-11-29 |
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