YU28495A - NEW AMINO ACID DERIVATIVES A PROCEDURE FOR THEIR PREPARATION AND THE PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS (II) - Google Patents

NEW AMINO ACID DERIVATIVES A PROCEDURE FOR THEIR PREPARATION AND THE PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS (II)

Info

Publication number
YU28495A
YU28495A YU28495A YU28495A YU28495A YU 28495 A YU28495 A YU 28495A YU 28495 A YU28495 A YU 28495A YU 28495 A YU28495 A YU 28495A YU 28495 A YU28495 A YU 28495A
Authority
YU
Yugoslavia
Prior art keywords
preparation
amino acid
acid derivatives
compounds
procedure
Prior art date
Application number
YU28495A
Other languages
Serbo-Croatian (sh)
Inventor
G. Schnorrenberg
F. Esser
H. Dollinger
B. Jung
G. Speck
E. Burger
Original Assignee
Boehringer Ingelheim Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg. filed Critical Boehringer Ingelheim Kg.
Publication of YU28495A publication Critical patent/YU28495A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NOVI DERIVATI AMINO KISELINE POSTUPAK ZA NJIHOVO PRIPREMANJE I FARMACEUTSKI PREPARATI KOJI SADRŽE OVA JEDINJENJA (II) - Pronalazak se odnosi na nove derivate amino kiseline, opšte formule R'-R^-A'-B i njihove farmaceutski prihvatljive soli, u kojoj grupa B označava -A2- NR2R3 ili R5, pri čemu R 1 Al A2 p2 R3 OS r6 p7 r8 ,M,M,n,n,n,ri,n,ri,R9, X, Y, Z, t i u imaju značenja navedena u opisu, kao i njihovo pripremanje i primenu. Nova jedinjenja su dragoceni antagonisti neurokinina (tahikinina).The invention relates to new amino acid derivatives, of general formula R'-R ^ -A'-B and their pharmaceutically acceptable salts, in which group B denotes -A2- NR2R3 or R5, wherein R 1 Al A2 p2 R3 OS r6 p7 r8, M, M, n, n, n, ri, n, ri, R9, X, Y, Z, tiu have the meanings given in description, as well as their preparation and application. The new compounds are valuable antagonists of neurokinin (tachykinin).

YU28495A 1994-05-07 1995-05-05 NEW AMINO ACID DERIVATIVES A PROCEDURE FOR THEIR PREPARATION AND THE PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS (II) YU28495A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4416255 1994-05-07
DE4445939A DE4445939A1 (en) 1994-05-07 1994-12-22 Novel amino acid derivatives, process for their preparation and pharmaceutical compositions containing them (II)

Publications (1)

Publication Number Publication Date
YU28495A true YU28495A (en) 1998-05-15

Family

ID=6517628

Family Applications (1)

Application Number Title Priority Date Filing Date
YU28495A YU28495A (en) 1994-05-07 1995-05-05 NEW AMINO ACID DERIVATIVES A PROCEDURE FOR THEIR PREPARATION AND THE PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS (II)

Country Status (6)

Country Link
KR (1) KR970702876A (en)
CO (1) CO4960643A1 (en)
DE (1) DE4445939A1 (en)
PE (1) PE14996A1 (en)
YU (1) YU28495A (en)
ZA (1) ZA953628B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19541283A1 (en) * 1995-11-06 1997-05-07 Boehringer Ingelheim Kg Novel amino acid derivatives, processes for their preparation and pharmaceutical compositions containing these compounds

Also Published As

Publication number Publication date
ZA953628B (en) 1995-11-07
KR970702876A (en) 1997-06-10
DE4445939A1 (en) 1995-11-09
CO4960643A1 (en) 2000-09-25
PE14996A1 (en) 1996-05-08

Similar Documents

Publication Publication Date Title
FI941987A (en) Novel amino acid derivatives, methods for their preparation and pharmaceutical compositions containing these compounds
YU8197A (en) Novel arylglycinamide derivatives, procedures for their preparation and pharmaceutical preparations containing these compositions
BR9813390A (en) Compound, process for preparing it, and use of it, pharmaceutical composition, process for preparing it, and, process for effecting immunosuppression
BG100946A (en) New amino acid derivatives, method for their preparation and pharmaceutical compositions containing them
CA2234610A1 (en) New amino acid derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
YU13396A (en) N-(3-benzofuranyl) urea derivatives, methods for preparation thereof, compositions containing them and their application in medicines
PT1254134E (en) 1,3-DIHYDRO-2H-INDOL-2-ONA DERIVATIVES AND THEIR USE AS LIGANDS FOR ARGININE-VASOPRESSIN V1B OR V1B AND V1A RECEPTORS
NO991384L (en) Substituted heterocycles as anti-tumor agents
NO930768D0 (en) SUBSTITUTED AMINOPHOSPHONATE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS THEREOF
FI963440A (en) The novel amino acid derivatives, the process for their preparation and the pharmaceutical compositions containing these compounds
YU28495A (en) NEW AMINO ACID DERIVATIVES A PROCEDURE FOR THEIR PREPARATION AND THE PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS (II)
RU95104890A (en) Novel steroids comprising aminosubstituted chain in 20-position, method and intermediate derivatives for preparing for said method, their usage as medicinals and pharmaceutical compounds comprising them
ATE293635T1 (en) STREPTOGRAMINE DERIVATIVES, THEIR PRODUCTION AND PREPARATIONS CONTAINING THEM
BR0011296A (en) Spiroimidazolidine derivatives, preparation thereof, use thereof and pharmaceutical preparations comprising the same
UY26971A1 (en) NEW NEUROQUININE ANTAGONISTS, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
ECSP951434A (en) NEW AMINO ACID DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS (II)
ECSP951394A (en) NEW AMINO ACID DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
UA27738C2 (en) 2,3,4,5,6,7-hexahydro-1-(4-(1-(4-(2-methoxyphenyl)piperazinyl))-2-phenylbutyryl)-1h-azepine or pharmaceutically acceptable acid addition salt thereof capable of binding to 5-ht receptors, processes for their preparation (variants) and pharmaceutical composition
CA2241788A1 (en) Novel n-(arylsulphonyl)amino acid derivatives, their preparation process and pharmaceutical compositions containing them