YU24501A - Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
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Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
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The present invention is directed to esters of (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-lorophenyl)ethyl] -4-piperidinemethanol, of formula (I) wherein R is C4-C20alkyl, pharmaceutical formulations, methods of making and methods of using these esters. These compounds antagonize the effects of serotonin at the 5HT2A receptor and are useful in treating various conditions such as, for example, psychoses such as schizophrenia.
YU24501A1998-10-141998-10-14Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
YU24501A
(en)
Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
Substituted indazole derivatives and their application as inhibitors of phosphodiesterase (pde) type iv and of the production of a tumournecrotic factor (tnf)
Esters of (+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 100,907
Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907
Esters of (+)-alpha-(2,3-dimethyloxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pi peridinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 100,907