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Application filed by F. Hoffmann-La Roche Ag.filedCriticalF. Hoffmann-La Roche Ag.
Priority to YU118491ApriorityCriticalpatent/YU48612B/sh
Priority to HRP-1184/91Aprioritypatent/HRP930501B1/xx
Publication of YU118491ApublicationCriticalpatent/YU118491A/sh
Publication of YU48612BpublicationCriticalpatent/YU48612B/sh
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Opisani su gvanidini formule: u kojoj označavaju R i R aril, heteroaril ili heterociklil, T CH2 ili O, L NH ili O i -N(X)-Mi to grupu -N(SO2-R )-CH2 ili u datom slučaju supstituisani izohinolilen, ili X predstavlja H, -CH2COOH, -CH2COO-C1-4-alkil, -CH2CON(CH2)4-7 ili u datom slučaju alkilovani -CH2CONH2, i M R'-(CH2)1-2CH=, R"-COCH2CH=, R'-COCH2CH=, R'-(CO)1-2NHCH2CH=, benzil-OCONHCH2CH=, -CH2/R'(CO)1-2NH/CH-,-CH2(benzil-OCONH)CH- ILI -CH(CO-Q)CH2-grupu, R" i R' aril, heteroaril, cikloalkil ili heterociklil, ili R" označava u datom slučaju supstituisani -N(CH2)4-7' Q benzilamino ili u datom slučaju sa 0-ili S-atomom prekinuti i u datom slučaju supstituisani -N(CH2)4-7' kao i hidrati ili solvati i njihove fiziološki prihvatljive soli.
YU118491A1990-07-051991-07-05Novi guanidini i postupak za njihovo dobijanje
YU48612B
(sh)
N-Acyl-S-(2-hydroxyalkyl)-cysteine, deren Herstellung sowie deren Verwendung als Zwischenprodukte zur Herstellung von synthetischen Immunadjuvantien und synthetischen Impfstoffen
1-dethia-2-thia-cephalosporansaeurederivate, verfahren zur herstellung, ihre verwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen.