YU118491A - NEW GUANIDINES AND THE PROCEDURE FOR OBTAINING THEM - Google Patents

NEW GUANIDINES AND THE PROCEDURE FOR OBTAINING THEM

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Publication number
YU118491A
YU118491A YU118491A YU118491A YU118491A YU 118491 A YU118491 A YU 118491A YU 118491 A YU118491 A YU 118491A YU 118491 A YU118491 A YU 118491A YU 118491 A YU118491 A YU 118491A
Authority
YU
Yugoslavia
Prior art keywords
optionally substituted
procedure
obtaining
guanidines
optionally
Prior art date
Application number
YU118491A
Other languages
Serbo-Croatian (sh)
Other versions
YU48612B (en
Inventor
J. Ackermann
D. Banner
K. Gubernator
P. Hadvary
K. Hilpert
K. Mueller
L. Labler
G. Schmid
T.B. Tschopp
H.P. Wessel
B. Wirz
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Priority to YU118491A priority Critical patent/YU48612B/en
Priority to HRP-1184/91A priority patent/HRP930501B1/en
Publication of YU118491A publication Critical patent/YU118491A/en
Publication of YU48612B publication Critical patent/YU48612B/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Opisani su gvanidini formule: u kojoj označavaju R i R aril, heteroaril ili heterociklil, T CH2 ili O, L NH ili O i -N(X)-Mi to grupu -N(SO2-R )-CH2 ili u datom slučaju supstituisani izohinolilen, ili X predstavlja H, -CH2COOH, -CH2COO-C1-4-alkil, -CH2CON(CH2)4-7 ili u datom slučaju alkilovani -CH2CONH2, i M R'-(CH2)1-2CH=, R"-COCH2CH=, R'-COCH2CH=, R'-(CO)1-2NHCH2CH=, benzil-OCONHCH2CH=, -CH2/R'(CO)1-2NH/CH-,-CH2(benzil-OCONH)CH- ILI -CH(CO-Q)CH2-grupu, R" i R' aril, heteroaril, cikloalkil ili heterociklil, ili R" označava u datom slučaju supstituisani -N(CH2)4-7' Q benzilamino ili u datom slučaju sa 0-ili S-atomom prekinuti i u datom slučaju supstituisani -N(CH2)4-7' kao i hidrati ili solvati i njihove fiziološki prihvatljive soli. Guanidines of the formula are described: in which R and R denote aryl, heteroaryl or heterocyclyl, T CH2 or O, L NH or O and -N (X) -Mi to the group -N (SO2-R) -CH2 or optionally substituted isoquinolylene, or X represents H, -CH2COOH, -CH2COO-C1-4-alkyl, -CH2CON (CH2) 4-7 or optionally alkylated -CH2CONH2, and M R '- (CH2) 1-2CH =, R " -COCH2CH =, R'-COCH2CH =, R '- (CO) 1-2NHCH2CH =, benzyl-OCONHCH2CH =, -CH2 / R' (CO) 1-2NH / CH -, - CH2 (benzyl-OCONH) CH- OR -CH (CO-Q) CH2-group, R "and R 'aryl, heteroaryl, cycloalkyl or heterocyclyl, or R" denotes optionally substituted -N (CH2) 4-7' Q benzylamino or optionally with 0 -or discontinued and optionally substituted -N (CH2) 4-7 'as well as hydrates or solvates and their physiologically acceptable salts.

YU118491A 1990-07-05 1991-07-05 Novel guanidines and process for obtaining thereof YU48612B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
YU118491A YU48612B (en) 1990-07-05 1991-07-05 Novel guanidines and process for obtaining thereof
HRP-1184/91A HRP930501B1 (en) 1990-07-05 1993-03-24 Guanidins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH225090 1990-07-05
YU118491A YU48612B (en) 1990-07-05 1991-07-05 Novel guanidines and process for obtaining thereof

Publications (2)

Publication Number Publication Date
YU118491A true YU118491A (en) 1994-01-20
YU48612B YU48612B (en) 1999-03-04

Family

ID=4229381

Family Applications (1)

Application Number Title Priority Date Filing Date
YU118491A YU48612B (en) 1990-07-05 1991-07-05 Novel guanidines and process for obtaining thereof

Country Status (3)

Country Link
HR (1) HRP930501B1 (en)
YU (1) YU48612B (en)
ZA (1) ZA915028B (en)

Also Published As

Publication number Publication date
HRP930501A2 (en) 1996-04-30
HRP930501B1 (en) 1998-08-31
ZA915028B (en) 1992-03-25
YU48612B (en) 1999-03-04

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