WO2024145908A1

WO2024145908A1 - Assembled externally-coated internally-integrated vial cap, and vial

Info

Publication number: WO2024145908A1
Application number: PCT/CN2023/070926
Authority: WO
Inventors: 刘师宏; 刘超
Original assignee: 湖南千山制药机械股份有限公司
Priority date: 2023-01-05
Filing date: 2023-01-06
Publication date: 2024-07-11

Abstract

A vial and an assembled externally-coated internally-integrated vial cap. The assembled externally-coated internally-integrated vial cap comprises a circular main body (100), an outer ring body (200) integrally formed with the edge of the lower end surface of the circular main body (100), an inner ring body (300) integrally formed with the lower end surface of the circular main body (100) and spaced apart from the outer ring body (200), and an upper ring body (500) integrally formed with the upper end surface of the circular main body (100); the lower end surface of the circular main body (100), the inner wall surface of the outer ring body (200), and the outer wall surface of the inner ring body (300) define a first seal cavity for accommodating a seal ring (400); the upper end surface of the circular main body (100) and the inner wall surface of the upper ring body (500) define a second seal cavity for accommodating a rubber stopper (600); the lower end surface of the circular main body (100) and the inner wall surface of the inner ring body (300) define a communication cavity; the upper ring body (500) is provided with a fixing structure (700); a seal film (800) is attached to the upper ring body (500) by welding; the outer ring body (200), the inner ring body (300), and the upper ring body (500) are coaxially arranged; the inner diameter of the outer ring body (200) is greater than the outer diameter of the inner ring body (300); and the middle of the circular main body (100) comprises a puncture part (110) arranged between the second seal cavity and the communication cavity and allowing for puncturing of an injection needle.

Description

Assemble the outer film-coated inner integrated vial cap and vial

Technical Field

The present invention relates to the technical field of vials, and in particular, to an assembled outer film inner integrated vial cap. In addition, the present invention also relates to a vial comprising the assembled outer film inner integrated vial cap.

Background technique

A vial is an injection bottle sealed with a rubber stopper and an aluminum-plastic combination cover, and is generally used for packaging vaccines, powder injections, freeze-dried medicines and other medicines.

However, when the aluminum-plastic composite cap is used to seal the bottle mouth of the vial, the aluminum-plastic composite cap is mainly rolled onto the bottle mouth with a piercing knife, which will cause the friction between the piercing knife and the aluminum-plastic composite cap to generate aluminum powder, thereby polluting the environment. In order to solve this problem, a composite cap structure is used to seal the bottle mouth of the vial, including a main cap and a sealing cap. The outer peripheral wall formed by the main cap extending downward and the annular wall formed by the sealing cap extending downward form a sealing cavity, and a sealing ring is arranged in the sealing cavity to achieve sealing by pressing and plugging with the bottle mouth of the vial through the sealing cavity. However, when performing the external seal to prevent the rubber plug from contacting the external environment, a snap-fit seal with an easily breakable structure is mainly used. This results in the outer seal of the rubber plug being relatively loose. When the easily breakable structure is broken or pulled off to expose the rubber plug, the rubber plug needs to be sterilized and disinfected again before the injection needle can be used to puncture the rubber plug to inject the drug. The operation process is very cumbersome and the drug injection efficiency is low. For example, Chinese utility model patent CN2017882947U discloses a vial packaging with a composite cap, which realizes the outer seal of the rubber plug by snap-fitting an easy-folding cap. Correspondingly, there is a problem of insufficient sealing. In addition, drug injection is mainly manually operated by medical staff, and there is interference from human factors. Once sterilization and disinfection are not in place, it is easy to bring additional safety risks to patients.

Summary of the invention

The present invention provides an assembled outer-film-covered and inner-integrated vial cap and vial, so as to solve the technical problems that the existing vial cap generates aluminum powder chips to pollute the environment during installation, or the rubber plug in the vial cap is not tightly sealed, so that additional sterilization and disinfection treatment is still required during use, which results in cumbersome operation.

According to one aspect of the present invention, there is provided an assembled outer-film inner integrated syringe bottle cap, comprising a circular main body for covering the bottle mouth of the syringe bottle, an outer ring body integrally formed with the edge of the lower end face of the circular main body for clamping with the bottle mouth of the syringe bottle, an inner ring body integrally formed with the lower end face of the circular main body and arranged at a distance from the outer ring body, and an upper ring body integrally formed with the upper end face of the circular main body, the lower end face of the circular main body, the inner wall surface of the outer ring body and the outer wall surface of the inner ring body enclose a first sealing cavity for accommodating a sealing ring, the upper end face of the circular main body and the inner wall surface of the upper ring body enclose a second sealing cavity for accommodating a rubber plug, the lower end face of the circular main body and the inner wall surface of the inner ring body enclose a connecting cavity for connecting to the inner cavity of the syringe bottle, a fixing structure for the rubber plug to fix the rubber plug in the second sealing cavity is provided on the upper ring body, a sealing film for sealing the upper end opening of the second sealing cavity is welded and attached to the upper ring body, the outer ring body, the inner ring body and the upper ring body are coaxially arranged, and the inner diameter of the outer ring body is larger than that of the inner ring body The outer diameter of the circular body is 200 mm, and the middle part of the circular body includes a puncture portion arranged between the second sealing cavity and the communicating cavity for puncture by an injection needle.

As a further improvement of the above technical solution:

Furthermore, a sinking portion extending axially downward is provided in the middle of the circular body, and a sinking groove formed by an axial depression and connected to the second sealing cavity is provided at the upper end of the sinking portion. The puncture portion is arranged at the bottom of the sinking groove and is used to separate the sinking groove and the connecting cavity.

Furthermore, the fixing structure includes an outer pressing edge bent and arranged on the upper end of the upper ring body for pressing the rubber plug by hot pressing and thereby fixing the rubber plug in the second sealing cavity, and the sealing film is welded and attached to the upper end surface of the outer pressing edge.

Furthermore, the fixing structure includes an outer clamping ring which is clamped with the inner wall of the second sealing cavity and is used to press the rubber plug to fix the rubber plug in the second sealing cavity. The upper end face of the outer clamping ring is lower than the upper end face of the upper ring body or is flush with the upper end face of the upper ring body, and the sealing film is welded and attached to the upper end face of the upper ring body.

Furthermore, a retaining protrusion is provided on the outer wall of the outer retaining ring, which extends obliquely axially upward and radially outward, and a retaining groove is provided on the inner wall of the second sealing cavity, which is recessed axially upward and radially outward. The retaining protrusion and the retaining groove are clamped and connected, and the upper end surface of the retaining protrusion and the upper end surface of the retaining groove are horizontally abutted.

Furthermore, the thickness of the puncture portion is 0.3 mm-0.5 mm.

Furthermore, the inner ring body is provided with a volatilization groove for connecting the first sealing cavity and the connecting cavity, and the inner wall of the outer ring body is provided with a limiting protrusion for squeezing and cooperating with the bottle mouth of the syringe bottle to limit the upward movement of the bottle mouth of the syringe bottle within a preset force, and the vertical height of the volatilization groove is lower than the vertical height of the sealing ring.

Furthermore, the inner diameter of the inner ring body is greater than the outer diameter of the upper ring body.

Furthermore, the inner diameter of the upper ring body is greater than the outer diameter of the inner ring body.

According to another aspect of the present invention, there is also provided a vial, which comprises the above-mentioned assembled outer-film inner integrated vial cap.

The present invention has the following beneficial effects:

The assembled outer-film inner-integrated syringe bottle cap of the present invention comprises a circular main body, an outer ring body, an inner ring body and an upper ring body which are formed together by an injection molding process, so that the lower end face of the circular main body, the inner wall face of the outer ring body and the outer wall face of the inner ring body are enclosed to form a first sealed cavity, a sealing ring is accommodated in the first sealed cavity and is plugged and matched with the bottle mouth of the syringe bottle, and then the outer ring body is clamped with the bottle mouth of the syringe bottle to be fixed on the bottle mouth of the syringe bottle, the sealing ring abuts against the bottle mouth of the syringe bottle to achieve sealing after fixation, a second sealed cavity is enclosed by the upper end face of the circular main body and the inner wall face of the upper ring body, a rubber plug is accommodated in the second sealed cavity, and then the rubber plug is pressed by a fixing structure to fix the rubber plug in the second sealed cavity to prevent the rubber plug from being brought out when the injection needle is pulled out, and finally the rubber plug is fixed by a fixing structure. The welding process welds the sealing film to the upper ring body to seal the upper end opening of the second sealing cavity. The outer seal is tight and reliable through face-to-face sealing to prevent the plug from contacting the external environment. When in use, only the sealing film needs to be torn off to expose the plug, which is convenient for medical staff to use. The inner wall surface of the inner ring body and the lower end surface of the circular main body are combined to form a connecting cavity connected to the inner cavity of the vial. Since the outer ring body, the inner ring body and the upper ring body are coaxially arranged, the second sealing cavity and the connecting cavity are coaxially arranged. After the injection needle passes through the second sealing cavity in the center along the axial direction, it will inevitably enter the connecting cavity, thereby realizing the injection of liquid medicine. Since the inner diameter of the outer ring body is larger than the outer diameter of the inner ring body, there must be a gap between the outer ring body and the inner ring body along the radial direction to form the first sealing cavity, and then by passing through The piercing portion facilitates the puncture of the injection needle and guides the puncture of the injection needle to reduce the difficulty of puncture. In this solution, the circular main body, the outer ring body, the inner ring body and the sealing ring cooperate with each other to be fixed to the bottle mouth of the syringe bottle and seal the bottle mouth of the syringe bottle. The circular main body, the upper ring body, the fixed structure and the sealing film are used to achieve reliable sealing of the rubber plug. Compared with the existing technology, the reliable sealing of the rubber plug is achieved without generating aluminum powder. No additional sterilization and disinfection is required during use. The operation is simple and convenient, the practicability is strong, and it is suitable for wide promotion and application.

In addition to the above-described objects, features and advantages, the present invention has other objects, features and advantages. The present invention will be further described in detail with reference to the accompanying drawings.

BRIEF DESCRIPTION OF THE DRAWINGS

The drawings constituting a part of this application are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the drawings:

FIG1 is a schematic diagram of the three-dimensional structure of an assembled outer-film inner-integrated penicillin bottle cap according to a preferred embodiment of the present invention;

FIG2 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG1 ;

FIG3 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG1 ;

FIG4 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG1 ;

FIG5 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG1 ;

FIG6 is a schematic diagram of the three-dimensional structure of an assembled outer-film inner-integrated penicillin bottle cap according to a preferred embodiment of the present invention;

FIG7 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG6;

FIG8 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG6;

FIG9 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG6 ;

FIG10 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap as shown in FIG6 ;

FIG11 is a schematic diagram of the three-dimensional structure of an assembled outer film inner integrated vial cap according to a preferred embodiment of the present invention;

FIG12 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG11;

FIG13 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG11;

FIG14 is a cross-sectional view of an embodiment of an assembled outer film inner integrated vial cap shown in FIG11;

FIG. 15 is a cross-sectional view of an embodiment of an assembled outer film inner integrated syringe bottle cap shown in FIG. 11 .

illustration:

100, circular body; 110, puncture part; 120, sinking part; 200, outer ring body; 210, limiting protrusion; 300, inner ring body; 310, volatilization groove; 400, sealing ring; 500, upper ring body; 600, rubber plug; 700, fixing structure; 710, outer pressure edge; 720, outer clamping ring; 721, clamping protrusion; 800, sealing membrane.

Detailed ways

The embodiments of the present invention are described in detail below with reference to the accompanying drawings. However, the present invention can be implemented in many different ways as defined and covered below.

Fig. 1 is a schematic diagram of the three-dimensional structure of an assembled outer film inner integrated penicillin bottle cap according to a preferred embodiment of the present invention; Fig. 2 is a cross-sectional view of an embodiment of an assembled outer film inner integrated penicillin bottle cap shown in Fig. 1; Fig. 3 is a cross-sectional view of an embodiment of an assembled outer film inner integrated penicillin bottle cap shown in Fig. 1; Fig. 4 is a cross-sectional view of an embodiment of an assembled outer film inner integrated penicillin bottle cap shown in Fig. 1; Fig. 5 is a cross-sectional view of an embodiment of an assembled outer film inner integrated penicillin bottle cap shown in Fig. 1; Fig. 6 is a schematic diagram of the three-dimensional structure of an assembled outer film inner integrated penicillin bottle cap according to a preferred embodiment of the present invention; Fig. 7 is a cross-sectional view of an embodiment of an assembled outer film inner integrated penicillin bottle cap shown in Fig. 6; Fig. 8 is a cross-sectional view of an assembled outer film inner integrated penicillin bottle cap shown in Fig. FIG. 9 is a cross-sectional view of an embodiment of an assembled outer-film inner integrated penicillin bottle cap shown in FIG. 6; FIG. 10 is a cross-sectional view of an embodiment of an assembled outer-film inner integrated penicillin bottle cap shown in FIG. 6; FIG. 11 is a schematic diagram of the three-dimensional structure of an assembled outer-film inner integrated penicillin bottle cap according to a preferred embodiment of the present invention; FIG. 12 is a cross-sectional view of an embodiment of an assembled outer-film inner integrated penicillin bottle cap shown in FIG. 11; FIG. 13 is a cross-sectional view of an embodiment of an assembled outer-film inner integrated penicillin bottle cap shown in FIG. 11; FIG. 14 is a cross-sectional view of an embodiment of an assembled outer-film inner integrated penicillin bottle cap shown in FIG. 11; FIG. 15 is a cross-sectional view of an embodiment of an assembled outer-film inner integrated penicillin bottle cap shown in FIG. 11.

Example 1

As shown in FIGS. 1 , 2 , 6 and 7 , the assembled outer-coated inner-integrated syringe bottle cap of the present embodiment comprises a circular main body 100 for covering the bottle mouth of the syringe bottle, an outer ring body 200 integrally formed with the lower end face edge of the circular main body 100 for clamping with the bottle mouth of the syringe bottle, an inner ring body 300 integrally formed with the lower end face of the circular main body 100 and arranged at intervals with the outer ring body 200, and an upper ring body 500 integrally formed with the upper end face of the circular main body 100. The lower end face of the circular main body 100, the inner wall surface of the outer ring body 200 and the outer wall surface of the inner ring body 300 enclose a first sealing cavity for accommodating a sealing ring 400. The upper end face of the circular main body 100 and the upper ring body 500 are integrally formed. The inner wall surface of the circular main body 100 encloses a second sealed cavity for accommodating the plug 600, the lower end surface of the circular main body 100 and the inner wall surface of the inner ring body 300 enclose a connecting cavity for connecting to the inner cavity of the vial, the upper ring body 500 is provided with a fixing structure 700 for the plug 600 to fix the plug 600 in the second sealed cavity, a sealing film 800 for sealing the upper end opening of the second sealed cavity is welded and attached to the upper ring body 500, the outer ring body 200, the inner ring body 300 and the upper ring body 500 are coaxially arranged, the inner diameter of the outer ring body 200 is larger than the outer diameter of the inner ring body 300, and the middle part of the circular main body 100 includes a puncture portion 110 for injection needle puncture arranged between the second sealed cavity and the connecting cavity. Specifically, in the assembled outer-film inner-integrated syringe bottle cap of the present invention, the circular main body 100, the outer ring body 200, the inner ring body 300 and the upper ring body 500 are formed together by an injection molding process, so that the lower end surface of the circular main body 100, the inner wall surface of the outer ring body 200 and the outer wall surface of the inner ring body 300 are enclosed to form a first sealed cavity, and the sealing ring 400 is accommodated in the first sealed cavity and plugged into and matched with the bottle mouth of the syringe bottle, and then the outer ring body 200 is clamped with the bottle mouth of the syringe bottle to be fixed on the bottle mouth of the syringe bottle, and the sealing ring 400 is abutted against the bottle mouth of the syringe bottle to achieve sealing after fixing, and the upper end surface of the circular main body 100 and the inner wall surface of the upper ring body 500 are enclosed to form a second sealed cavity, so as to pass The second sealed cavity accommodates the plug 600, and then the plug 600 is pressed by the fixing structure 700 to fix the plug 600 in the second sealed cavity to prevent the plug 600 from being pulled out when the injection needle is pulled out. Finally, the sealing film 800 is welded and attached to the upper ring body 500 by welding technology to seal the upper end opening of the second sealed cavity. The surface-to-surface sealing is tight and reliable to prevent the plug 600 from contacting the external environment. When in use, only the sealing film 800 needs to be torn to expose the plug 600, which is convenient for medical staff to use. The inner wall surface of the inner ring body 300 and the lower end surface of the circular main body 100 enclose a connecting cavity connected to the inner cavity of the vial, and because the outer ring body 200 and the inner ring body The outer ring body 200 and the inner ring body 300 are coaxially arranged, and the second sealed cavity and the connecting cavity are coaxially arranged. After the injection needle passes through the second sealed cavity in the middle along the axial direction, it must enter the connecting cavity, so as to achieve the injection of liquid medicine. Since the inner diameter of the outer ring body 200 is greater than the outer diameter of the inner ring body 300, there must be a gap between the outer ring body 200 and the inner ring body 300 along the radial direction to form a first sealed cavity, and then the puncture portion 110 is used to facilitate the puncture of the injection needle and guide the puncture of the injection needle to reduce the difficulty of puncture. The body 200, the inner ring body 300 and the sealing ring 400 cooperate with each other to be fixed to the bottle mouth of the vial and seal the bottle mouth of the vial, and then the reliable sealing of the plug 600 is achieved through the circular main body 100, the upper ring body 500, the fixed structure 700 and the sealing film 800. Compared with the prior art, the reliable sealing of the plug 600 is achieved without generating aluminum powder, and no additional sterilization and disinfection treatment is required during use. The operation is simple and convenient, and the practicability is strong, which is suitable for wide promotion and application. It should be understood that the injection molding process and the welding process are both well-known technologies of those skilled in the art, and will not be described in detail here. Optionally, the outer ring body 200 is provided with a clamping portion extending radially inward to be clamped with the bottle mouth of the vial.

In this embodiment, the fixing structure 700 includes an outer pressure edge 710 bent and arranged on the upper end of the upper ring body 500, which is used to press the plug 600 by hot pressing and bending, and then fix the plug 600 in the second sealing cavity, and the sealing film 800 is welded and attached to the upper end surface of the outer pressure edge 710. Specifically, during the injection molding process, the upper end of the upper ring body 500 is firstly injection-molded axially upward to form an unbent outer pressure edge 710, and after the injection molding is completed, the outer pressure edge 710 is formed by hot pressing and bending by a hot pressing process to press the plug 600 and fix the plug 600 in the second sealing cavity, and then the sealing film 800 is welded and attached to the upper end surface of the outer pressure edge 710 to achieve sealing of the upper end opening of the second sealing cavity. During the hot pressing process, the matrix density of the outer pressure edge 710 increases and it fits tightly with the upper end surface of the plug 600, so that it is fixed reliably. Optionally, the outer pressure edge 710 is arranged in a ring shape, and the inner wall surface of the outer pressure edge 710 encloses a puncture port for injection needle puncture, and the injection needle is guided through the puncture port to reduce the difficulty of puncture. Optionally, a bending concave angle is recessed between the outer pressure edge 710 and the upper ring body 500 for facilitating bending and fixing the length. The outer pressure edge 710 is bent at the bending concave angle during the bending process, which greatly reduces the difficulty of bending, and makes the length of the outer pressure edge 710 relatively fixed, improves the assembly accuracy of the outer pressure edge 710 when pressing and fixing the rubber plug 600, and has a compact structure and high reliability. It should be understood that the hot pressing process is a well-known technology of those skilled in the art and will not be described in detail here.

In this embodiment, the thickness of the puncture portion 110 is 0.3mm-0.5mm. Specifically, the puncture portion 110 is formed together during the injection molding process of the circular body 100. Therefore, when the thickness of the puncture portion 110 is between 0.3mm-0.5mm, the injection molding difficulty of the puncture portion 110 is low and it is convenient for the injection needle to puncture. When the thickness of the puncture portion 110 is less than 0.3mm, it is easy to break during the injection molding process and the injection molding difficulty is high; when the thickness of the puncture portion 110 is greater than 0.5mm, the puncture difficulty is high. Preferably, the thickness of the puncture portion 110 is 0.4mm.

In this embodiment, the inner ring body 300 is provided with a volatilization groove 310 for connecting the first sealing cavity and the connecting cavity, and the inner wall of the outer ring body 200 is provided with a limiting protrusion 210 for squeezing and cooperating with the bottle mouth of the syringe bottle to limit the upward movement of the bottle mouth of the syringe bottle within a preset force, and the vertical height of the volatilization groove 310 is lower than the vertical height of the sealing ring 400. Specifically, when the vial is used to contain freeze-dried drugs, the moisture of the freeze-dried drugs needs to be volatilized during the freezing process. When the first sealed cavity is pressed into the mouth of the vial, the limiting protrusion 210 is squeezed and matched with the mouth of the vial to limit the upward movement of the mouth of the vial within a preset force, so that the vial is in a semi-covered state, and the internal moisture can be volatilized through the volatilization groove 310. When all the moisture is volatilized, the circular body 100 is pressed with a force greater than the preset force to completely compact the vial cap, so that the mouth of the vial and the sealing ring 400 are pressed against each other to achieve complete sealing of the vial. Optionally, a plurality of volatilization grooves 310 are arranged at intervals along the circumference of the inner ring body 300.

In this embodiment, the inner diameter of the inner ring body 300 is larger than the outer diameter of the upper ring body 500. Specifically, when using a vial containing a powder injection or a lyophilized drug, it is first necessary to use an injection needle to inject a solution to dissolve the powder injection or lyophilized drug. After the drug is arranged in a liquid state, another injection needle can be inserted to suck the liquid drug in the vial. In the process of drug dissolution, the vial is often shaken to increase the dissolution rate. Therefore, it is necessary to have enough internal space in the vial to ensure the fluidity of the drug during shaking and vibration. Therefore, by making the inner diameter of the inner ring body 300 larger than the outer diameter of the upper ring body 500, the inner diameter of the connecting cavity is larger than the first sealed cavity, and then there is enough internal space to achieve the flow dissolution of the drug inside the vial during oscillation.

Example 2

As shown in Figures 3, 5, 8, 10, 13 and 15, the difference between this embodiment and Embodiment 1 is that a sinking portion 120 extending axially downward is provided in the middle portion of the circular main body 100, and an upper end portion of the sinking portion 120 is provided with a sinking groove formed by an axial depression and connected to the second sealing cavity, and the puncture portion 110 is arranged at the bottom of the sinking groove and is used to separate the sinking groove and the connecting cavity. Specifically, the second sealed cavity contains the rubber plug 600, and the injection needle needs to puncture the rubber plug 600 and then puncture the puncture part 110 to enter the connecting cavity. If the injection needle punctures the rubber plug 600 and then directly punctures the puncture part 110, the injection needle will encounter great puncture resistance, and insoluble particles are likely to be generated in the process of puncturing the rubber plug 600 and brought into the vial. However, the rubber plug 600 and the puncture part 110 are spaced apart by the sinking groove, so that after the injection needle punctures the rubber plug 600, the needle tip of the injection needle is extended and then punctures the puncture part 110, which greatly reduces the puncture resistance, minimizes or avoids the generation of insoluble particles, and even if insoluble particles are generated, they will be blocked in the sinking groove and will not be brought into the connecting cavity. Optionally, the depth of the sinking groove is 1.5mm-2.5mm. When the depth of the sinking groove is between 1.5mm-2.5mm, the needle head of the injection needle has sufficient space for expansion, and the material consumption of the sinking part 120 is relatively appropriate, and the material cost is low; when the depth of the sinking groove is less than 1.5mm, the expansion space of the needle head of the injection needle is small, and the puncture resistance is large; when the depth of the sinking groove is greater than 2.5mm, the material consumption of the sinking part 120 is too much, and the material cost is high. Preferably, the depth of the sinking groove is 2mm. It should be understood that the sinking groove is formed by the inner wall of the sinking part 120 and the upper end surface of the puncture part 110. When the thickness of the puncture part 110 remains unchanged, the material consumption of the sinking part 120 is positively correlated with the depth of the sinking groove.

Example 3

As shown in Figures 4, 5, 9, 10, 14 and 15, the difference between this embodiment and Embodiment 1 is that the fixing structure 700 includes an outer clamping ring 720 which is clamped with the inner wall of the second sealing cavity and is used to press the rubber plug 600 to fix the rubber plug 600 in the second sealing cavity, the upper end face of the outer clamping ring 720 is lower than the upper end face of the upper ring body 500 or is flush with the upper end face of the upper ring body 500, and the sealing film 800 is welded and attached to the upper end face of the upper ring body 500. Specifically, the outer retaining ring 720 is pressed into the second sealing cavity along the axial direction to engage with the inner wall of the second sealing cavity, and then the rubber plug 600 is pressed to fix the rubber plug 600 in the second sealing cavity. The sealing film 800 is then welded and attached to the upper end surface of the upper ring body 500 by a welding process to achieve the sealing of the upper end opening of the second sealing cavity. Since the upper end surface of the outer retaining ring 720 is lower than the upper end surface of the upper ring body 500 or is flush with the upper end surface of the upper ring body 500, it will not hinder the horizontal sealing of the sealing film 800, thereby greatly improving the sealing performance. In addition, the engaging form of the outer retaining ring 720 is convenient for assembly and disassembly.

In this embodiment, a holding protrusion 721 extending obliquely axially upward and radially outward is provided on the outer wall of the outer clamping ring 720, and a holding groove recessed axially upward and radially outward is provided on the inner wall of the second sealing cavity. The holding protrusion 721 is connected to the holding groove by a clamping connection, and the upper end surface of the holding protrusion 721 and the upper end surface of the holding groove are horizontally abutted. Specifically, in the process of pressing the outer pressure ring axially downward into the second sealing cavity, the holding protrusion 721 is deformed by pressure until it is clamped into the holding groove. At this time, the holding protrusion 721 and the holding groove are connected by a clamping connection, and the upper end surface of the holding protrusion 721 and the upper end surface of the holding groove are horizontally abutted, so as to tightly fix the rubber plug 600 when the injection needle is pulled out to prevent the rubber plug 600 from being taken out. It should be understood that when the vial is used to store powder injections or lyophilized drugs, it is first necessary to inject physiological saline or glucose or other solutions of similar properties through the injection needle to make the drug in the vial liquid, and then the injection needle is pulled out, and another injection needle is inserted to aspirate the drug to achieve liquid injection. Therefore, when pulling out the injection needle, it is necessary to prevent the rubber plug 600 from being pulled out by the injection needle to ensure that the rubber plug 600 can achieve a tight seal on the next injection needle.

Example 4

As shown in Figures 11-15, the difference between this embodiment and embodiment 1 is that the inner diameter of the upper ring body 500 is larger than the outer diameter of the inner ring body 300. Specifically, when using a vial containing a vaccine, it is only necessary to insert the injection needle and then aspirate the vaccine. However, since the vaccine dose is relatively small, it is necessary to avoid vaccine residues when the injection needle aspirates the vaccine as much as possible. During the aspiration process, the vial is usually turned upside down to use gravity to make the vaccine flow into the connecting cavity and be aspirated by the injection needle. At this time, the vaccine in the connecting cavity that is lower than the needle tip of the injection needle will not be able to be aspirated. Therefore, by making the inner diameter of the upper ring body 500 larger than the outer diameter of the inner ring body 300, so that the inner diameter of the connecting cavity is smaller than the inner diameter of the second sealed cavity, so that the internal space of the connecting cavity is relatively small, the amount of vaccine that cannot be aspirated is indirectly reduced, and vaccine residues are avoided as much as possible.

The vial of this embodiment includes the assembled outer film inner integrated vial cap of any of the above embodiments. Specifically, the vial mouth of the vial is sealed by using the assembled outer film inner integrated vial cap to achieve reliable sealing of the rubber stopper 600 without generating aluminum powder, which greatly reduces the difficulty of using the vial, is convenient for medical staff to use, has strong practicality, and is suitable for wide promotion and application.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

An assembled outer-film-coated inner-integrated syringe bottle cap is characterized in that it comprises a circular main body (100) for covering the bottle mouth of the syringe bottle, an outer ring body (200) integrally formed with the lower end surface edge of the circular main body (100) for clamping with the bottle mouth of the syringe bottle, an inner ring body (300) integrally formed with the lower end surface of the circular main body (100) and arranged at intervals with the outer ring body (200), and an upper ring body (500) integrally formed with the upper end surface of the circular main body (100), the lower end surface of the circular main body (100), the inner wall surface of the outer ring body (200) and the outer wall surface of the inner ring body (300) enclose a first sealing cavity for accommodating a sealing ring (400), and the upper end surface of the circular main body (100) and the inner wall surface of the upper ring body (500) enclose a first sealing cavity for accommodating a sealing ring (400), and the upper end surface of the circular main body (100) and the inner wall surface of the upper ring body (500) enclose a first sealing cavity for accommodating a sealing ring (400). A second sealed cavity for accommodating a rubber plug (600), the lower end surface of the circular main body (100) and the inner wall surface of the inner ring body (300) enclose a connecting cavity for connecting to the inner cavity of a vial, the upper ring body (500) is provided with a fixing structure (700) for the rubber plug (600) to fix the rubber plug (600) in the second sealed cavity, a sealing film (800) for sealing the upper end opening of the second sealed cavity is welded and attached to the upper ring body (500), the outer ring body (200), the inner ring body (300) and the upper ring body (500) are coaxially arranged, the inner diameter of the outer ring body (200) is larger than the outer diameter of the inner ring body (300), and the middle part of the circular main body (100) includes a puncture portion (110) arranged between the second sealed cavity and the connecting cavity for injection needle puncture.
The assembled outer film inner integrated syringe bottle cap according to claim 1 is characterized in that a sinking portion (120) extending axially downward is provided in the middle of the circular main body (100), and an upper end of the sinking portion (120) is provided with a sinking groove formed by an axial depression and connected to the second sealing cavity, and the puncture portion (110) is arranged at the bottom of the sinking groove and is used to separate the sinking groove and the connecting cavity.
The assembled outer film inner integrated syringe bottle cap according to claim 1 is characterized in that the fixing structure (700) includes an outer pressing edge (710) bent and arranged on the upper end portion of the upper ring body (500) for pressing the rubber plug (600) by hot pressing and bending to fix the rubber plug (600) in the second sealing cavity, and the sealing film (800) is welded and attached to the upper end surface of the outer pressing edge (710).
The assembled outer film inner integrated syringe bottle cap according to claim 1 is characterized in that the fixing structure (700) includes an outer clamping ring (720) which is clamped with the inner wall of the second sealing cavity and is used to press the rubber plug (600) to fix the rubber plug (600) in the second sealing cavity, and the upper end surface of the outer clamping ring (720) is lower than the upper end surface of the upper ring body (500) or is flush with the upper end surface of the upper ring body (500), and the sealing film (800) is welded and attached to the upper end surface of the upper ring body (500).
The assembled outer-coated and inner-integrated syringe bottle cap according to claim 4 is characterized in that a holding protrusion (721) extending obliquely axially upward and radially outward is provided on the outer wall of the outer clamping ring (720), and a holding groove recessed axially upward and radially outward is provided on the inner wall of the second sealing cavity, the holding protrusion (721) and the holding groove are clamped and connected, and the upper end surface of the holding protrusion (721) and the upper end surface of the holding groove are horizontally abutted.
The assembled outer-film inner-integrated syringe bottle cap according to claim 1 is characterized in that the thickness of the puncture portion (110) is 0.3 mm-0.5 mm.
The assembled outer-film inner-integrated syringe bottle cap according to claim 1 is characterized in that the inner ring body (300) is provided with a volatilization groove (310) for connecting the first sealing cavity and the connecting cavity, and the inner wall of the outer ring body (200) is provided with a limiting protrusion (210) for squeezing and cooperating with the bottle mouth of the syringe bottle to limit the upward movement of the bottle mouth of the syringe bottle within a preset force, and the vertical height of the volatilization groove (310) is lower than the vertical height of the sealing ring (400).
The assembled outer-film inner-integrated syringe bottle cap according to claim 1 is characterized in that the inner diameter of the inner ring body (300) is larger than the outer diameter of the upper ring body (500).
The assembled outer-film inner-integrated syringe bottle cap according to claim 1 is characterized in that the inner diameter of the upper ring body (500) is larger than the outer diameter of the inner ring body (300).
A syringe bottle, characterized by comprising the assembled outer film inner integrated syringe bottle cap according to claim 1.