WO2024128510A1

WO2024128510A1 - Device for nasal administration of drug

Info

Publication number: WO2024128510A1
Application number: PCT/KR2023/016123
Authority: WO
Inventors: 김관영; 이경민; 최종서; 이재원; 전양원
Original assignee: 주식회사 대웅제약
Priority date: 2022-12-13
Filing date: 2023-10-18
Publication date: 2024-06-20
Also published as: KR20240088467A

Abstract

The present invention relates to a device for nasal administration of a drug and comprises a container part and a nozzle part. The container part accommodates powdered medicine and has a guiding part which has a guiding hole provided at the upper end to guide the powdered medicine toward the guiding hole. The nozzle part is coupled to the upper portion of the container part and is inserted into the nasal cavity of a patient to spray the powdered medicine. In addition, the nozzle part comprises: a measuring part, which is in communication with the guiding part to measure a predetermined amount of the powdered medicine that has been guided thereto through the guiding part; and a flow tube, which is in communication with the measuring part and through which the powdered medicine measured by the measuring part moves along with internal air and is discharged when the container part is pressed. The central axis of the measuring part is arranged to be spaced apart from the central axis of the flow tube.

Description

Nasal medication device

The present invention relates to a nasal medication device, and more specifically, to a nasal medication device capable of administering powdered medicine into the nasal cavity.

Various devices have been proposed for administering drugs to a patient's nasal cavity. Among these, a nasal medication device that inserts a nozzle attached to a container storing the drug into the patient's nasal cavity and discharges the drug through the inserted nozzle is the most widely used.

At this time, the patient must administer an appropriate amount of drug in order to be treated effectively without causing risk. However, since conventional nasal medication devices are not equipped with a separate device to measure the appropriate amount of drug, the patient must administer the appropriate amount of drug on his or her own. It is difficult to administer.

In particular, for young children who have more difficulty administering an appropriate amount of medication on their own, there is a problem that serious side effects may occur if excessive medication is administered.

Accordingly, there is a need for a nasal medication device that has a simple configuration and allows patients to measure an appropriate amount of medication on their own.

Accordingly, the problem to be solved by the present invention is to solve such conventional problems, and is to provide a nasal medication device that allows patients to measure an appropriate amount of drug on their own with a simple configuration.

A nasal medication device according to an embodiment of the present invention for solving the above-described problems includes a container portion that accommodates a powder medication, is provided with an induction hole at the upper end, and has an induction portion that guides the powder medication toward the guide hole; And a nozzle unit coupled to the upper side of the container unit and inserted into the patient's nasal cavity to spray the powder medicine, wherein the nozzle part communicates with the guide part and a metering part through which the powder medicine guided through the guide part is metered in a predetermined amount. and a flow pipe that is in communication with the metering unit and is discharged while flowing the powdered medicine measured in the metering unit together with the internal air when the container unit is pressurized, and the central axis of the metering unit is formed to be spaced apart from the central axis of the flow pipe. It is characterized by A nasal medication device.

In addition, the nasal medication device according to an embodiment of the present invention for solving the above-described problem includes a collection space in which the metered powder medicine is collected by the metering unit, and a collection space in which the powder medicine guided through the guide part is fed into the collection space. While guiding, it may have a protrusion that prevents the powdered medicine from flowing back into the container through the guide hole.

In addition, in the nasal medication device according to an embodiment of the present invention to solve the above-described problem, the guide portion is formed so that the width becomes narrower toward the top, and the guide hole may be located inside the metering portion.

In addition, in the nasal medication device according to an embodiment of the present invention to solve the above-described problem, the flow pipe may be formed by expanding a portion of the flow pipe so that the powder drug is scattered in the process of spraying the powder drug. there is.

In addition, the nasal medication device according to an embodiment of the present invention for solving the above-mentioned problem is that the nozzle part is rotatably installed in the container part, and the metering part is installed to be spaced apart from each other, but first metering units of different sizes are provided. It has a measuring unit and a second measuring unit, and when the nozzle unit is rotated, either the first measuring unit or the second measuring unit can be communicated with the guiding unit.

In addition, the nasal medication device according to an embodiment of the present invention for solving the above-mentioned problem, the guiding part has a first guiding part and a second guiding part installed to be spaced apart from each other at the upper end of the container part, and the metering part has the first guiding part and the second guiding part. It may have a first metering part that communicates with the first guide part, and a second metering part that communicates with the second guide part and has a different size from the first meter.

In addition, the nasal medication device according to an embodiment of the present invention for solving the above-described problem is rotatably installed between the container portion and the nozzle portion, and rotates to the inlet portion of the first metering portion or the second It may have a rotating plate that selectively opens and closes the entrance to the metering unit.

According to the nasal medication device of the present invention, by including a measuring unit, there is an effect of measuring the appropriate amount of powdered medicine required for the patient.

In addition, according to the nasal medication device of the present invention, by including the protrusion, there is an effect of effectively guiding the powdered medicine to the collection space and preventing the powdered medicine from flowing back into the container through the guide hole.

In addition, according to the nasal medication device of the present invention, the central axis of the metering unit is formed to be spaced apart from the central axis of the flow pipe, so that even if the container unit is turned over, the powdered medicine does not flow directly through the flow pipe, but effectively measures a certain amount in the metering unit.

In addition, according to the nasal medication device of the present invention, the guide portion is formed to become narrower toward the top and the guide hole is located inside the metering portion, so the diameter of the guide hole narrows and the gap between the guide hole and the protrusion also narrows. When the powder medicine guided to the collection unit falls, it is possible to more effectively prevent the powder medicine from flowing back into the container unit through the guide hole.

In addition, according to the nasal medication device of the present invention, the flow tube is formed by expanding a portion of the flow tube, so that the powder medicine flowing in the flow tube may scatter during the spraying process, so the flow tube is not blocked by agglomeration of the powder medicine, so the powder medicine is not blocked. It has the effect of being more effectively discharged into the patient's nasal cavity.

In addition, according to the nasal medication device of the present invention, by having the first and second metering parts of different sizes, different amounts of powdered medicine can be metered, which has the effect of improving the versatility of the nasal medication device. .

1 is a diagram showing a nasal medication device according to an embodiment of the present invention;

Figure 2 is a diagram explaining how the protrusions of the nasal medication device of Figure 1 guide the powdered medicine to the collection space and prevent the powdered medicine from flowing back into the container part;

Figure 3 is a diagram showing another embodiment of the guiding part of the nasal medication device of Figure 1;

Figure 4 is a diagram showing another embodiment of the nasal medication device according to the present invention;

Figure 5 is a diagram showing the operation of rotating the nozzle portion of the nasal medication device of Figure 4;

Figure 6 is a diagram showing another embodiment of the nasal medication device according to the present invention;

FIG. 7 is a diagram illustrating how the rotating plate of the nasal medication device of FIG. 6 selectively opens and closes the entrance to the first metering unit or the entrance to the second metering unit.

Hereinafter, preferred embodiments of the present invention, in which the above-described problem to be solved can be concretely realized, will be described with reference to the attached drawings.

Figure 1 is a diagram showing a nasal medication device according to an embodiment of the present invention, and Figure 2 shows that the protrusions of the nasal medication device of Figure 1 guide the powder medication into the collection space while the powder medication flows back into the container portion. It is a diagram explaining prevention, and Figure 3 is a diagram showing another embodiment of the guide part of the nasal medication device of Figure 1, and Figure 4 is a diagram showing another embodiment of the nasal medication device according to the present invention. FIG. 5 is a diagram showing the operation of rotating the nozzle portion of the nasal medication device of FIG. 4, FIG. 6 is a diagram showing another embodiment of the nasal medication device according to the present invention, and FIG. 7 is a diagram showing the operation of rotating the nozzle portion of the nasal medication device of FIG. 4. This is a diagram showing that the rotating plate of the nasal medication device selectively opens and closes the entrance to the first metering unit or the entrance to the second metering unit.

Referring to Figure 1, the nasal medication device according to an embodiment of the present invention includes a container unit 100 and a nozzle unit 200.

The container unit 100 is a container in which the powdered medicine 10 is accommodated, and is provided with a guiding hole 111 at the upper end and has a guiding part 110 that guides the powdered medicine 10 toward the guiding hole 111. The guide portion 110 is formed in a funnel shape, and the container portion 100 can be tilted or turned over to guide the powdered medicine 10 toward the guide hole 111. At this time, the guide hole 111 preferably has a diameter of 3 mm or less.

In addition, the container unit 100 is made of an elastic material and can be pressurized. When pressurized, the air inside the container unit 100 can be moved toward the nozzle unit 200, which will be described later, through the guide hole 111. .

The nozzle unit 200 is coupled to the upper side of the container unit 100 and may be formed to protrude at a predetermined height, and is inserted into the patient's nasal cavity to spray the powdered medicine 10. And, the nozzle unit 200 includes a metering unit 210 and a flow pipe 220.

The measuring unit 210 is in communication with the guiding unit 110 and the powdered medicine 10 guided through the guiding unit 110 is metered at a certain amount. In other words, the measuring unit 210 can measure the appropriate amount of powdered medicine 10 needed for the patient. In addition, the metering unit 210 may have a collection space 211 and a protrusion 212.

The collection space 211 can collect the measured powder drug 10. The collection space 211 may be an inner space of the metering unit 210 on both sides of the protrusion 212.

The protrusion 212 guides the powdered medicine 10 guided through the guiding part 110 to the collection space 211, and prevents the powdered medicine from flowing back into the container part 100 through the guiding hole 111. there is. The protrusion 212 may be formed by protruding the upper end of the metering unit 210 facing the induction hole 111 in the inner direction of the metering unit 210 .

Specifically, with reference to FIG. 2 , it will be explained that the protrusion 212 guides the powdered medicine 10 into the collection space 211 and prevents the backflow of the powdered medicine 10.

As shown in (a) of FIG. 2, the metering unit 210 has a protrusion 212 formed by protruding the upper end of the metering unit 210 facing the induction hole 111 in the inner direction of the metering unit 210. There may be a collection space (211) on both sides of (212).

And, as shown in (b) of FIG. 2, when the container part 100 containing the powder medicine 10 is turned over, the powder medicine 10 is guided toward the guide hole 111 through the guide part 110 and reaches the metering part. It can flow into (210). At this time, the powdered medicine 10 may be guided by the protrusion 212 to the collection portions 213 on both sides of the protrusion 212.

Thereafter, as shown in (c) of FIG. 2, when the container part 100 is turned over again, the powdered medicine 10 guided to the collection part 213 falls and at this time, the protrusion on the upper side of the guide hole 111 By (212), it can be collected in the collection space 211 without flowing back into the container unit 100.

Accordingly, the metering unit 210 includes a collection space 211 and a protrusion 212 to prevent the powdered medicine 10 from flowing back into the container unit 100 through the guide hole 111 and to store the powdered medicine 10. It can be measured in a certain amount.

Meanwhile, the guide portion 110 is formed to become narrower toward the top, and the guide hole 111a may be located inside the metering portion 210.

Referring to FIG. 3, the guide portion 110 is formed to become narrower toward the top and has a protrusion 112 that protrudes into the inner space of the metering portion 210, so that the guide hole 111a is formed to become narrower toward the upper side. ) can be located inside.

By being formed in this way, the diameter of the guidance hole 111a narrows and the gap between the guidance hole 111a and the protrusion 212 also narrows, so when the powdered medicine 10 guided to the collection unit 213 falls, It is possible to more effectively prevent the powdered medicine 10 from flowing back into the container unit 100 through the guide hole 111.

The flow pipe 220 is a pipe in communication with the metering unit 210 through which the powdered medicine 10 flows. When the container part 100 is pressurized, the powdered medicine 10 measured in the metering part 210 is supplied along with the internal air. It may flow through the flow tube 220 and be discharged into the patient's nasal cavity.

At this time, referring again to FIG. 1, the central axis A1 of the metering unit 210 and the central axis A2 of the flow pipe 220 are formed to be spaced apart.

If the central axis (A1) of the metering unit (210) and the central axis (A2) of the flow tube (220) are not formed to be spaced apart but are formed to coincide with each other, when the container unit (100) is turned over, the powdered medicine (10) After being guided toward the guide hole 111 by the guide part 110 and flowing into the metering part 210, it may continue to flow into the flow pipe 220 without being collected in the collection space 211.

In this case, not only is the powdered medicine 10 not measured in a certain amount, but an excessive amount of the powdered medicine 10 may flow directly into the patient's nasal cavity, which may cause a serious situation for the patient.

Therefore, the central axis A1 of the metering unit 210 and the central axis A2 of the flow pipe 220 are formed to be spaced apart, so that even if the container unit 110 is turned over, the powdered medicine 10 flows directly through the flow pipe 220. Since it does not flow, a certain amount can be effectively metered to the metering unit 210.

Meanwhile, the flow pipe 220 may be formed by expanding a portion of the flow pipe 220 so that the powdered drug 10 scatters during the process of spraying the powdered drug 10.

Continuing to refer to FIG. 1 , the flow pipe 220 may maintain a constant diameter at the lower end connected to the metering unit 210 and may have an expansion portion 221 in which a portion of the flow pipe is expanded.

In this way, the flow tube 220 has the expansion part 221 and is formed by expanding some areas, so that the powder medicine 10 flowing through the flow tube 220 may scatter during the spraying process, thereby preventing agglomeration of the powder medicine 10. As a result, the flow pipe 220 is not blocked and the powdered medicine 10 can be more effectively discharged into the patient's nasal cavity.

Figures 4 and 5 are diagrams showing another embodiment of the nasal medication device according to the present invention, and in this embodiment, content repeated with the embodiment of Figure 1 is omitted as much as possible.

Referring to Figures 4 and 5, the nozzle unit 300 of the nasal medication device according to the present invention can be rotatably installed in the container unit 100, and the metering units are installed to be spaced apart from each other, but are of different sizes. It may have a first metering unit 310 and a second metering unit 320. Also, when the nozzle unit 300 is rotated, either the first metering unit 310 or the second metering unit 320 may be in communication with the guide unit 110.

First, the metering units are installed to be spaced apart from each other and have a first metering part 310 and a second metering part 320 of different sizes, so that different amounts of powdered medicine 10 can be metered.

Meanwhile, the amount of powdered medicine needed by the patient may vary depending on the patient's age, health condition, or type of powdered medicine. For example, when the patient is a child, the amount of powdered medicine required is relatively small compared to an adult, so it is preferable to measure the powdered medicine through the second measuring unit 320, which is larger in size.

At this time, as shown in (b) of FIG. 5, the nozzle unit 300 is rotated so that the guide unit 110 communicates with the second metering unit 320. Even if the container part 100 is turned over, the powdered medicine 10 can be allowed to flow only into the second metering part 320 and not into the first metering part 310 .

Therefore, the nozzle unit 300 is rotatably installed in the container unit 100 and has a first metering part 310 and a second metering part 320 of different sizes, so that different amounts of powdered medicine 10 can be used. ) can be measured, which has the effect of improving the versatility of the nasal medication device.

Figures 6 and 7 are diagrams showing another embodiment of the nasal medication device according to the present invention, and in this embodiment, content repeated with the embodiments of Figures 1 and 4 is omitted as much as possible.

Referring to Figures 6 and 7, the guiding part of the nasal medication device according to the present invention has a first guiding part 410 and a second guiding part 430 installed at the upper end of the container part 400 to be spaced apart from each other, and The unit may have a first metering unit 310 in communication with the first guide part 410, and a second metering part 330 in communication with the second guide part 430 but having a different size from the first metering part 310. .

And, it is rotatably installed between the container unit 400 and the nozzle unit 300, and rotates to form the inlet 314 of the first metering unit 310 or the inlet part 334 of the second metering unit 330. It may have a rotating plate 500 that selectively opens and closes.

Specifically, when the amount of powder medication required by the patient is relatively large, the inlet 314 of the first metering unit 310 is closed by rotating the rotary plate 500 as shown in (a) of FIG. The inlet portion 334 of the second metering unit 330 can be opened to allow powdered medicine to flow only into the second metering unit 330 when the container unit 400 is turned over.

Additionally, when the amount of powdered medicine needed by the patient is relatively small, the inlet portion 314 of the first metering unit 310 is opened by rotating the rotary plate 500 as shown in (b) of FIG. 7 and the second metering unit 310 is opened. The inlet 334 of the metering unit 330 can be closed to allow powdered medicine to flow only into the first metering unit 310 when the container unit 400 is turned over.

The nasal medication device according to the present invention, configured as described above, includes a measuring unit and can achieve the effect of measuring an appropriate amount of powdered medicine required for the patient.

In addition, the nasal medication device according to the present invention configured as described above includes a protrusion in the metering portion, which has the effect of effectively guiding the powdered medicine to the collection space and preventing the powdered medicine from flowing back into the container through the guide hole. You can get it.

In addition, in the nasal medication device according to the present invention configured as described above, the central axis of the metering unit is formed to be spaced apart from the central axis of the flow pipe, so that even if the container unit is turned over, the powdered medicine does not flow directly through the flow pipe and effectively measures a certain amount in the metering unit. You can achieve this effect.

In addition, in the nasal medication device according to the present invention configured as described above, the guide portion is formed so that the width becomes narrower toward the upper side, and the guide hole is located inside the metering portion, so that the diameter of the guide hole narrows and the width between the guide hole and the protrusion is narrowed. Since the gap between the is narrowed, when the powdered medicine guided to the collection unit falls, it is possible to more effectively prevent the powdered medicine from flowing back into the container unit through the guide hole.

In addition, in the nasal medication device according to the present invention configured as described above, the flow tube is formed by expanding a portion of the flow tube, so the powder medicine flowing in the flow tube may scatter during the spraying process, so the flow tube may be damaged by agglomeration of the powder medicine. Since this is not blocked, the powdered medicine can be discharged more effectively into the patient's nasal cavity.

In addition, the nasal medication device according to the present invention configured as described above has a first metering unit and a second metering unit of different sizes, so that different amounts of powdered medicine can be metered, thereby increasing the versatility of the nasal medication device. Improved effects can be achieved.

The scope of the present invention is not limited to the above-described embodiments and modifications, but may be implemented in various forms within the scope of the appended claims. It is considered to be within the scope of the claims of the present invention to the extent that anyone skilled in the art can make modifications without departing from the gist of the invention as claimed in the claims.

The present invention has industrial applicability in the field of medical device technology capable of administering powdered medicine into the nasal cavity.

Claims

A container portion that accommodates the powdered medicine, is provided with an induction hole at the upper end, and has a guiding part that guides the powdered medicine toward the induction hole; and

A nozzle unit coupled to the upper side of the container unit and inserted into the patient's nasal cavity through which the powder medicine is sprayed,

The nozzle part

a metering part that communicates with the guiding part and measures a predetermined amount of powdered medicine guided through the guiding part; and a flow pipe that communicates with the metering part and discharges the powdered medicine measured in the metering part as it flows with the internal air when the container part is pressurized. Includes,

A nasal medication device, characterized in that the central axis of the metering unit is formed to be spaced apart from the central axis of the flow pipe.
According to paragraph 1,

The weighing unit

A collection space where the measured powder medicine is collected,

A nasal medication device, characterized in that it has a protrusion that guides the powdered medicine guided through the guide part into the collection space and prevents the powdered medicine from flowing back into the container part through the guide hole.
According to paragraph 1,

A nasal medication device, wherein the guide portion is formed to become narrower toward the top, and the guide hole is located inside the metering portion.
According to paragraph 1,

The flow tube is a nasal medication device, characterized in that a portion of the flow tube is expanded so that the powder medicine is scattered during the process of spraying the powder medicine.
According to paragraph 1,

The nozzle unit is rotatably installed in the container unit,

The metering units are installed spaced apart from each other and have a first metering part and a second metering part of different sizes,

A nasal medication device, characterized in that when the nozzle unit is rotated, either the first metering unit or the second metering unit communicates with the guide unit.
According to paragraph 1,

The guide part has a first guide part and a second guide part installed at an upper end of the container part to be spaced apart from each other,

A nasal medication device characterized in that the metering unit has a first metering part in communication with the first guide part, and a second metering part in communication with the second guide part but having a different size from the first metering part.
According to clause 6,

A nasal medication device, characterized in that it has a rotating plate rotatably installed between the container unit and the nozzle unit to selectively open and close the inlet part of the first metering part or the inlet part of the second metering part while rotating.