JP3328131B2 - Inhaler type dispenser - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an inhalation type dispenser suitable for administering a powdered drug (medicine powder) into the lungs by inhaling a patient's breath, for example.

[0002]

2. Description of the Related Art In general, a method of administering a drug to the lungs of an asthma patient or the like includes a method of injecting a drug solution, a method of inhaling with a liquid aerosol sprayer, and a method of powdering a drug powder containing chamber or capsule. A method of inhaling a medicine (hereinafter referred to as a medicine powder) is used.

[0003] Among these drug administration methods for asthma patients,
The method of inhaling the medicinal powder filled in the capsule is as follows: an asthmatic patient attaches the capsule to an inhaler for aspirating the medicinal powder, and breaks the capsule using a puncture needle, so that the medicinal powder in the capsule is inhaled from the inhaler. Is inhaled with air.

[0004]

By the way, in the inhaler using the capsule system according to the prior art, the capsule is filled by utilizing the air flow generated in the inhaler when a patient inhales air from the inlet. The medicine powder thus sucked is sucked into the lung from the inlet. Therefore, when the suction force from the suction port is weak, a sufficient air flow cannot be generated in the inhaler, so that the medicine powder in the capsule and the medicine powder flowing out of the capsule can be effectively stirred. Without
There is a problem that the dispersibility, dischargeability, etc. of the medicinal powder are reduced, thereby lowering the administration efficiency.

[0005] In particular, when the patient is an elderly person or a child having a weak suction force, the medicinal powder remains on the inner wall surface or the like in the capsule, and the dosage of the medicinal powder varies, and the prescribed amount of the medicinal powder is given to the patient. There is a problem that the medicinal powder cannot be administered and the administration efficiency is reduced.

SUMMARY OF THE INVENTION The present invention has been made in view of the above-mentioned problems in the prior art, and effectively disperses the powdered medicine by effectively stirring the powdered powder flowing out to the inhaler side, thereby dispensing a prescribed amount of powdered medicine to the patient. It is an object of the present invention to provide an inhalation type dispenser capable of surely administering the drug to the lung.

[0007]

In order to solve the above-mentioned problems, an inhaler-type dispenser according to the first aspect of the present invention comprises: a dispenser main body having an inlet through which a patient inhales a medicinal powder; a medicine powder accommodating chamber Ru extends axially positioned within the body, and inlet air passage for communicating the drug powder storage chamber and the atmosphere side, outlet side which communicates with the suction port and the drug powder storage chamber from the air passage
The inhaler type dispenser ,
Today, a diaphragm portion positioned in the middle of the suction inlet, the the narrowed portion
Nde and mixed-chamber you mixed leaked medicine powder from located in the agent powder containing chamber side the outlet air passage, said across the throttle portion
A mixing chamber located on the opposite side is provided an opening out injection you ejected through the throttle unit medicine powder from the mixing chamber, the outlet-side ventilation
The path extends obliquely with respect to the powder storage chamber.
Wherein an accommodation chamber that has a configuration for communicating with the mixing chamber
It is with.

According to the above configuration, when the patient inhales while holding the suction port of the main body of the dispenser, the air sucked from the atmosphere side flows sequentially through the inflow side ventilation path, the medicine powder storage chamber, and the outflow side ventilation path. When air passes through the medicine-powder storage chamber, the medicine powder in the medicine-powder storage chamber is conveyed by the airflow into the suction port through the outflow-side ventilation path. And, in the mixing chamber formed by the restricting portion located in the suction port, the medicine powder collection is performed.
Turbulence is generated by the air <br/> airflow flowing out from the outflow-side air passage which is inclined obliquely with respect to the vessel chamber, while diffusing mixing the air more medicine powder to the turbulence and mixing in air medicine Or opening the powder
It can be administered to the lungs of Luo patient.

According to a second aspect of the present invention, the dispenser main body includes
An auxiliary ventilation path is provided for communicating the mixing chamber formed by the throttle section with the atmosphere side separately from the passage composed of the inflow-side ventilation path and the outflow-side ventilation path.

[0010] With the above structure, the air flowing into the mixing chamber can flow out not only from the air flow containing the chemical powder flowing out through the outflow-side ventilation path but also from the auxiliary ventilation path. The turbulence in the mixing chamber can be largely generated, and the dispersibility of the chemical powder can be enhanced.

According to a third aspect of the present invention, an opening portion of the auxiliary ventilation path is formed obliquely with respect to a wall surface of the mixing chamber so that the air flowing out of the auxiliary ventilation path into the mixing chamber is swirled. is there.

With the above structure, the air flow flowing out of the auxiliary ventilation path into the mixing chamber is generated as a swirling flow in the mixing chamber, and is combined with the air flow flowing out of the outflow side ventilation path. The turbulence in the water can be increased, and the dispersibility of the medicinal powder can be increased. Further, in the invention according to claim 4, the diaphragm
The part consists of one or more throttle passages
is there.

[0013]

Embodiments of the present invention will be described below in detail with reference to the accompanying drawings.

First, FIGS. 1 to 3 show a first embodiment of the present invention.

In the drawing, reference numeral 1 denotes an outer shell of an inhaler type dispenser, and a suction piece which forms a main body of the dispenser together with a capsule holder 6 to be described later. It is configured.

Reference numeral 2 denotes one axial side of the suction piece 1 (inflow side).
And a guide cylindrical portion 2A for guiding a support portion 13 of a drilling tool 12, which will be described later, protrudes radially outward from an outer peripheral side of the holder accommodating portion 2. ing.

The guide cylinder 2 of the holder housing 2
Pin holes 4 and 5 penetrating therethrough are formed in the radial direction, respectively, and the pin holes 4 correspond to the pin insertion holes 9B of the inflow-side ventilation passages 9 described later, and the pin holes 5 correspond to the outflow-side ventilation passages. It corresponds to ten pin insertion holes 10B.

Reference numeral 6 denotes a capsule holder which is inserted into the holder accommodating portion 2 and constitutes the dispenser main body together with the suction piece 1. The capsule holder 6 is formed in a columnar shape, and has a holder accommodating portion on one end side outer periphery. An annular stopper portion 6A that fits on one end side of the holder 2 is formed, and the capsule holder 6 is positioned in the holder accommodating portion 2 by the stopper portion 6A. On one end side of the capsule holder 6, a capsule insertion guide 7, which is reduced in diameter from the outer periphery at one end toward the center and forms a capsule insertion opening for guiding the capsule K into a capsule storage chamber 8 described later, is formed. I have.

Further, at the center of the capsule holder 6,
A capsule housing chamber 8 having a bottomed hole extending in the axial direction and opening to the capsule insertion guide 7 is formed, and the capsule housing chamber 8 is filled with a powdery medicine (hereinafter referred to as medicine powder). A capsule K (shown in FIG. 3) is inserted from one side.

Reference numerals 9 and 9 denote two inflow-side air passages provided on one side of the capsule holder 6, respectively.
An inflow passage 9A which is located on the outer peripheral side of the capsule housing chamber 8 and is formed so that one side is opened to the capsule insertion guide 7 and the other side is formed so as to be inclined so as to approach the capsule housing chamber 8; And a pin insertion hole 9B formed in the radial direction so as to open to the inner periphery of the communication capsule housing chamber 8. Each of the pin insertion holes 9 </ b> B is arranged coaxially with the pin hole 4, and the pin hole 4 </ b>
One of the pin insertion holes 9B located on the side is formed as a through hole, the other pin insertion hole 9B is formed as a bottomed hole,
The needle tip 14A of the pin 14 of the drilling tool 12 described later is received.

Reference numerals 10 and 10 denote two outflow-side ventilation passages provided on the other side of the capsule holder 6, and each of the outflow-side ventilation passages 10 is located on the outer peripheral side of the capsule housing chamber 8 and has one side. The outflow passage 1 is formed so as to be inclined so as to approach the capsule accommodating chamber 8 and open on the other side to a mixing chamber 17 described later.
0A and a pin insertion hole 1 formed in the radial direction so as to communicate with the outflow passage 10A and open to the inner periphery of the capsule housing chamber 8.
0B. And each of the pin insertion holes 1
0B is arranged coaxially with the pin hole 5, and one of the pin insertion holes 10B located on the pin hole 5 side with respect to the capsule accommodation chamber 8.
Is formed as a through hole, and the other pin insertion hole 10B is formed as a bottomed hole so as to receive the needle tip 14A of the pin 14.

Since the inflow passages 9A of the respective inflow-side ventilation passages 9 are formed so as to be inclined with respect to the capsule housing chamber 8, the air flowing from the capsule insertion guide 7 through the inflow passages 9A allows the air to flow into the capsule K. Speed up when entering the
The dispersibility of the medicinal powder and air in the capsule K can be increased. Further, since the outflow passages 10A of the respective outflow-side ventilation passages 10 are formed so as to be inclined with respect to the capsule housing chamber 8, the mixing chamber 1 is separated from the capsule housing chamber 8 through the outflow passages 10A.
The speed at which the air flowing into the mixing chamber 7 flows into the mixing chamber 17 can be increased, the turbulence in the mixing chamber 17 can be increased, and the dispersibility of the chemical powder can be increased.

Reference numerals 11 and 11 denote two auxiliary air passages formed so as to penetrate the capsule holder 6 in the axial direction at positions shifted from the passages formed by the inflow side air passages 9 and the outflow side air passages 10 by about 90 degrees. And each of the auxiliary ventilation paths 11 is provided with a mixing chamber 17.
Communicates with the atmosphere without passing through the capsule accommodation room 8,
The amount of air circulating at the time of inhalation is increased to eliminate breathlessness, and turbulence in the mixing chamber 17 is increased by supplying air into the mixing chamber 17.

Reference numeral 12 denotes a drilling tool provided in the holder accommodating portion 2 for drilling a total of four holes H, H,... Which are located at both axial ends of the capsule K and penetrate in the radial direction. Reference numeral 12 denotes a support portion 13 movably provided in the guide tube portion 2A, and a base end side is fixed to the support portion 13 and a distal end side is provided with pin insertion holes of the ventilation passages 9 and 10 through pin holes 4 and 5. 9
B, 10B, which are roughly composed of pins 14 inserted therein. The tip of each pin 14 is a sharp needle tip 14A for making each hole H in the capsule K. Further, a spring 15 is disposed between the support portion 13 and the holder accommodating portion 2 to urge each pin 14 to return to the initial position via the support portion 13. And the drilling tool 12
When the support portion 13 is pushed toward the holder accommodating portion 2, the needle tip 14A of each pin 14 is moved from the pin holes 4 and 5 into the capsule K in the capsule accommodating chamber 8 through the pin insertion holes 9B and 10B. To form four holes H in the capsule K.

Reference numeral 16 denotes a position in the suction port 3 in the longitudinal direction.
Shows the diaphragm portion integrally formed in, the narrowed portion 16 becomes passage 16A diaphragm small diameter portion, the intake port 3 by the narrowed portion 16, position in the capsule housing chamber 8 side across the throttle section 16
And a mixing chamber 17 for mixing the chemical powder flowing out from each of the outflow side ventilation passages 10 with the mixing chamber 17 with the throttle unit 16 interposed therebetween.
The medicine from the mixing chamber 16 is located on the opposite side to the opening side of the suction port 3.
And an ejection opening 18 through which the powder is ejected through the throttle section 16.
Have been.

Here, in the mixing chamber 17 located on the inflow side, the chemical powder conveyed from the capsule K passes through each outflow side air passage 1.
Air flowing out of the outflow passage 10A and the auxiliary air passages 1
The powder and the air are mixed so as to be diffused by a turbulent flow formed by the air flowing out of 1 to enhance the dispersibility of the powder.

On the other hand, the air containing the chemical powder mixed in the mixing chamber 17 flows out through the throttle passage 16A into the ejection opening 18 located on the opening side of the suction port 3, and the ejection opening 18 Squirt into the patient's mouth.

The inhaler-type dispenser according to the present embodiment has the above-described configuration. Next, the operation for inhaling the medicinal powder by the patient will be described with reference to FIG.

First, the capsule K is inserted into the capsule storage chamber 8 from one side. At this time, since one end surface of the capsule holder 6 serves as a capsule insertion guide 7, the capsule K can be easily guided into the capsule storage chamber 8.

In order to make holes H, H,... In the capsule K, the support portion 13 of the hole-making tool 12 is pushed toward the holder accommodating portion 2 and the needle tip 14A of each pin 14 is connected to each of the ventilation paths 9,
The capsule 10 is moved from the pin insertion holes 9B and 10B of the capsule 10 to the capsule storage chamber 8 and penetrated through the capsule K in the capsule storage chamber 8 to the bottoms of the pin insertion holes 9B and 10B on the opposite side. Four holes H can be formed in K. After each hole H is formed in the capsule K, the external force applied to the support portion 13 is removed, so that the spring 1
5, the pins 14 are inserted into the pin insertion holes 9B, 10B.
B, extracted from the capsule K and returned to the initial position.

Next, the flow of air in the inhaler and the movement of the powder when the patient inhales the powder will be described.

First, when the patient holds the inhalation port 3 by mouth and inhales, as shown in FIG. 3, air flows from each inflow side ventilation path 9 into the inhaler-type dispenser, and each inflow side ventilation path 9 Flows into the capsule K from the inflow passage 9A of each of the inflow-side ventilation passages 9 through the pin insertion holes 9B and the holes H, and mixes the medicine powder in the capsule K by the air flow. Mix in.

At this time, the inflow passage 9 of each inflow side ventilation passage 9
A is formed so as to be inclined with respect to the capsule storage chamber 8, so that the speed at which the air flowing from the capsule insertion guide 7 flows into the capsule K is increased, and the medicine powder and the air in the capsule K are increased. And dispersibility can be increased.

As described above, the chemical powder mixed into the air in the capsule K is removed from the capsule K through the holes H and the outflow-side ventilation passages 1.
It flows out into the mixing chamber 17 through the pin insertion hole 10B and the outflow passage 10A.

In the mixing chamber 17, a turbulent flow is generated by the air flowing out through the outflow passage 10A together with the chemical powder and the air flowing out through the auxiliary ventilation passage 11.
The powder that has flowed out due to this turbulence collides with the wall surface or the powder repeatedly collides with each other, and the powder that has been solidified is mixed so as to diffuse uniformly, thereby improving the dispersibility of the powder in the air. Can be.

At this time, since the outflow passages 10A of the respective outflow side ventilation passages 10 are formed so as to be inclined with respect to the capsule housing chamber 8, the capsule housing chambers 8 are formed through the outflow passages 10A.
The speed at which the air flowing out of the mixing chamber 17 flows out into the mixing chamber 17 is increased, and the turbulence in the mixing chamber 17 is increased. As a result, the dispersibility of the chemical powder in the mixing chamber 17 can be improved.

Further, the chemical powder diffused into the air by the mixing chamber 17 is carried along with the air flow to form the throttle passage 16 of the throttle section 16.
A: It is ejected from the suction port 3 through the ejection opening 18 and passes through the mouth, trachea and the like of the patient and reaches the lungs.

On the other hand, the capsule container room 8
Are provided, two auxiliary ventilation paths 11 are provided to communicate between the capsule insertion guide 7 and the mixing chamber 17, so that when the patient inhales, the air is also circulated from each auxiliary ventilation path 11. It can eliminate the stuffiness when breathing in.

Thus, according to the present embodiment, the mixing chamber 17 is formed on the inflow side by the throttle 16 in the suction port 3 and the ejection opening 18 is formed on the outflow side. Due to the turbulence generated by the air flowing into the inside, the medicine powder flowing out of the capsule K from the capsule K into the mixing chamber 17 can be mixed to enhance the dispersibility of the medicine powder. The medicine powder with improved dispersibility is conveyed into the lungs of the patient together with air through the squeezing passage 16A of the squeezing section 16 and the ejection opening 18, thereby improving the medication efficiency.

[0040]

Next, FIGS. 4 to 6 show a second embodiment according to the present invention.
In this embodiment, the feature of the present embodiment is that the suction port and the restricting portion forming the suction piece are formed by different members, and the portion where the auxiliary ventilation passage opens to the mixing chamber is formed on the wall surface of the mixing chamber. It is formed diagonally. In this embodiment, the same components as those in the above-described first embodiment are denoted by the same reference numerals, and description thereof will be omitted.

In the figure, reference numeral 21 designates the outer shell of the inhalation type dispenser,
A suction piece that forms a main body of the dispenser together with a capsule holder 26 described later is shown.
And the suction port 23, and the holder accommodating portion 22 and the suction port 23 are integrally formed.

Reference numeral 22 denotes a substantially cylindrical holder receiving portion provided on one side (inflow side) in the axial direction of the suction piece 21. On the outer peripheral side of the holder receiving portion 22, a support portion for a drilling tool 31 described later is provided. A guide tube portion 22A for guiding the protrusion 32 projects radially outward.

The guide cylinder 2 of the holder housing 22
2A, through-holes 24, 25 are formed in the radial direction, respectively.
9 correspond to the pin insertion holes 29B, and the pin holes 25 correspond to the pin insertion holes 30B of the respective outflow side ventilation paths 30.

Reference numeral 26 denotes a capsule holder which is inserted into the holder accommodating portion 22 and constitutes the main body of the dispenser together with the suction piece 1. The capsule holder 26 is formed in a columnar shape, and has a holder accommodating portion on one end side outer periphery. An annular stopper 26A is formed on one end side of the stopper 22.
By A, the capsule holder 26 is positioned in the holder accommodating portion 22. Also, capsule holder 2
6, on one end side, the diameter is reduced from one end outer periphery toward the center,
A capsule insertion guide 27 serving as a capsule insertion opening for guiding the capsule K into a capsule storage chamber 28 described later is formed.

Further, in the center of the capsule holder 26, a capsule receiving chamber 28 having a bottomed hole extending in the axial direction and opening to the capsule inserting guide 27 is formed. Similarly to 3, the capsule K filled with the medicine powder is inserted from one side.

Reference numerals 29, 29 denote two inflow-side air passages provided on one side of the capsule holder 26. Each of the inflow-side air passages 29 is located on the outer peripheral side of the capsule accommodating chamber 28, and one side is a capsule. An inflow passage 29A that is open to the insertion guide 27 and is inclined so that the other side approaches the capsule housing chamber 28, and has a diameter that communicates with the inflow passage 29A and opens to the inner periphery of the capsule housing chamber 28. And a pin insertion hole 29B formed in the direction. Each of the pin insertion holes 29B is arranged coaxially with the pin hole 5, and one of the pin insertion holes 29B located on the pin hole 24 side with respect to the capsule housing chamber 28 is formed as a through hole, and the other pin insertion hole is formed. The hole 29B is a bottomed hole, and receives a needle tip 33A of a pin 33 of the drilling tool 31 described later.

Reference numerals 30 and 30 denote two outflow-side ventilation passages provided on the other side of the capsule holder 26. Each of the outflow-side ventilation passages 30 is located on the outer peripheral side of the capsule storage chamber 28 and has one side. The outflow passage 30A is formed so as to be inclined so as to approach the capsule housing chamber 28, and the other side is opened to a mixing chamber 36 to be described later, and communicates with the outflow passage 30A and opens to the inner periphery of the capsule housing chamber 28. And a pin insertion hole 30B formed in the radial direction as described above. Each of the pin insertion holes 30B is arranged coaxially with the pin hole 25, and one of the pin insertion holes 30B located on the pin hole 25 side with respect to the capsule storage chamber 28 is formed as a through hole, and the other pin insertion hole 30B is formed. The hole 30B is a bottomed hole, and the needle tip 33 of the pin 33 is used.
A is to be accepted.

The inflow passage 29 of each inflow side ventilation passage 29
Since A is formed to be inclined with respect to the capsule storage chamber 28, the speed of the air flowing out of the capsule insertion guide 27 is increased when flowing into the capsule K, and the dispersion of the medicinal powder and air in the capsule K is performed. Since the outflow passages 30A of the respective outflow-side ventilation passages 30 are formed to be inclined with respect to the capsule storage chamber 28, the air flowing out of the capsule storage chamber 28 into the mixing chamber 36 flows out to the mixing chamber 36. And the turbulence in the mixing chamber 36 is increased to enhance the dispersibility of the chemical powder.

Reference numeral 31 denotes a drilling tool provided in the holder accommodating portion 22 for drilling a total of four holes H, H,... Penetrating in the radial direction at both ends in the axial direction of the capsule K. Reference numeral 31 denotes a support portion 32 movably provided in the guide tube portion 22A, and a base end side is fixed to the support portion 32, and a distal end side is a pin insertion hole of each of the ventilation paths 29, 30 through pin holes 24, 25. Each of the pins 33 has a sharp needle point 33A for making a hole H in the capsule K. A spring 34 is provided between the support portion 32 and the holder accommodating portion 22 to urge each pin 33 to return to the initial position via the support portion 32. When the supporter 32 is pushed toward the holder accommodating portion 22, the hole-piercing tool 31 moves the needle point 33A of each pin 33 from the pin holes 24, 25 via the pin insertion holes 29B, 30B to the capsule accommodating chamber. In this case, four holes H are formed in the capsule K.

Reference numeral 35 denotes a cylindrical throttle forming member which forms a throttle portion provided by being inserted into the suction port 23. The throttle forming member 35 has a small-diameter throttle passage 35A. As a result, the mixing chamber 36 and the ejection opening 37 are provided in the suction port 23.
In the mixing chamber 36 located on the inflow side, the medicine powder flowing out of the capsule K is supplied to each of the outflow side ventilation passages 30.
A turbulent flow is formed by the air flowing out of the outflow passage 30A and the air flowing out of the auxiliary ventilation passage 38 described later, and the turbulent flow mixes the medicine powder and the air well to enhance the dispersibility of the medicine powder. Also, the ejection opening 3 located on the opening side of the suction port 23.
The air containing the chemical powder diffused in the mixing chamber 36 flows out of the mixing chamber 36 through the throttle passage 35A, and this air flow is jetted into the mouth of the patient.

Reference numerals 38, 38 denote auxiliary air passages according to the present embodiment . Each of the auxiliary air passages 38 is approximately 90 degrees with each of the inflow side air passage 29 and the outflow side air passage 30, as shown in FIGS. At the shifted position, the capsule holder 26 and the aperture forming member 35
Are formed so as to penetrate in the axial direction. Also,
Openings 38 that open into the mixing chamber 36 of each of the auxiliary ventilation paths 38
As shown in FIG. 6 , A is formed obliquely in the tangential direction with respect to the wall surface of the mixing chamber 36. And
Each of the auxiliary ventilation paths 38 communicates the atmosphere side with the mixing chamber 36 to increase the amount of air flowing during inhalation to eliminate breathlessness, and to supply air into the mixing chamber 36 to supply air to the mixing chamber 36. To increase the turbulence inside. Further, in each auxiliary ventilation passage 38 according to the present embodiment, since the opening 38A that opens to the mixing chamber 36 is formed obliquely to the wall surface of the mixing chamber 36, a swirling flow may be generated in the mixing chamber 36. it can.

Thus, in the present embodiment having the above-described structure, substantially the same operation and effect as those of the first embodiment can be obtained. An opening 38A that opens into the chamber 36,
The turbulent flow generated in the mixing chamber 36 can be generated as a swirling flow because the turbulent flow is formed so as to be substantially tangential to the wall surface of the mixing chamber 36. As a result, the mixing of the medicine powder and air in the mixing chamber 36 can be more uniformly mixed than in the first embodiment, and the dispersibility of the medicine powder can be increased, thereby improving the administration efficiency.

Next, FIG. 7 shows a third embodiment of the present invention . The feature of this embodiment is that the shape of the aperture forming member is different from that of the first embodiment. On the side, a plurality of throttle passages communicating the mixing chamber and the end face are formed. In this embodiment, the same components as those in the above-described second embodiment are denoted by the same reference numerals, and description thereof will be omitted.

[0055] In the figure, 41 is I the throttle portion according to the present embodiment which is provided in place of the diaphragm member 35 in the second embodiment
The diaphragm forming member 41 is formed in a columnar shape, and communicates with the mixing chamber 42 formed by a concave recessed portion opened at one side end face, and the mixing chamber 42 and the other side end face. , For example, four throttle passages 43 formed so as to increase in diameter from one side to the other side. The throttle forming member 41 is configured such that the inside of the suction port 23 is a mixing chamber 42 on one side ,
Defining the ejection opening 44. In addition, each throttle passage 43
Disperses air containing the medicinal powder mixed in the mixing chamber 42,
This enhances the directivity and allows it to flow out to the ejection opening 44 side.
You.

Reference numerals 45 and 45 denote auxiliary air passages according to the present embodiment. Each of the auxiliary air passages 45 is formed with the capsule holder 26 and the throttle at a position shifted from the inflow air passage 29 and the outflow air passage 30 by about 90 degrees. Two are formed so as to penetrate the member 41 in the axial direction. In addition, the mixing chamber 4 of each of the auxiliary ventilation passages 45
Similarly to the opening 38A of the auxiliary ventilation passage 38 according to the second embodiment, the opening 45A opening to the second 2 is formed so as to be oblique in the tangential direction with respect to the wall surface of the mixing chamber 42.

[0057] In an inhaling type medicine administering apparatus of the present embodiment thus configured, since the operation is the same as the second real 施例 described above, although the explanation is omitted, in this embodiment, the diaphragm The air flowing from the mixing chamber 42 to the ejection opening 44 can be made to flow linearly by the respective throttle passages 43 of the forming member 41, and the directivity of the ejection opening 44 can be enhanced. As a result, the medicine powder ejected from the ejection opening 44 can be reduced from adhering to the inside of the patient's mouth, and the dosage in the lung can be increased.

[0058]

[0059] Further, in each of the foregoing embodiments, inserts a capsule K in the capsule accommodating chamber 8 (2 8) in the hole in the drilling tool 12 (31) in the capsule K H, H, by forming a ..., Although the explanation has been given by taking as an example a dispenser in which the powder in the capsule K is inhaled, a powder storage chamber is provided in place of the capsule storage chamber, and one dose of the powder is distributed into the powder storage chamber. ,
The present invention may be applied to a dispenser adapted to inhale the powder.

Further, in each of the above embodiments, the auxiliary air passage 1
1 (38, 45) is formed in the axial direction of the capsule holder 6 (26). However, the present invention is not limited to this. 36,
42) and the atmosphere side.

[0061]

As described in detail above, according to the first aspect of the present invention, when the patient inhales while holding the inlet of the main body of the dispenser, the air sucked from the atmosphere side flows into the inflow side ventilation passage, The storage chamber flows sequentially with the outflow-side ventilation path, and when air passes through the medicine-powder storage chamber, the medicine powder in the medicine-powder storage chamber is conveyed into the suction port through the outflow-side ventilation path by this airflow, It is discharged into the mixing chamber located in the suction port. Here, in the mixing chamber, a turbulent flow is generated by the airflow flowing out of the outflow-side ventilation passage obliquely inclined with respect to the medicine powder storage chamber. Mixed indoors
It can, through the ejection opening in a state of enhanced dispersibility of the medicine powder can administer the medicine powder into the lungs of a patient, whereby it is possible to increase the dosage efficiency.

[0062] According to the present invention 2, the administering device main body, because the medicine powder storage chamber mixing chamber formed by the diaphragm portion are separately provided auxiliary air passage which communicates with the atmosphere side,
Air flowing into the mixing chamber, not only the air stream containing spilled medicine powder through the outflow-side air passage, even air can be the outflow into the mixing chamber from the auxiliary air passage, in the mixing chamber by the air stream increasing the turbulence that occurs, it is possible to increase the dosage efficiency by increasing the dispersibility of the medicine powder.

According to the third aspect of the present invention , since the portion of the auxiliary ventilation path that opens to the mixing chamber is formed obliquely to the wall surface of the mixing chamber, the airflow flowing out of the auxiliary ventilation path into the mixing chamber is reduced. In addition, a swirl flow is generated in the mixing chamber, and the turbulence generated in the mixing chamber is increased in combination with the air flow flowing out of the outflow-side air passage, thereby improving the dispersibility of the medicinal powder and improving the administration efficiency. . In the invention of claim 4, since the structure Ri by the one or more restriction passage aperture section, the air containing the mixed medicine powder in the mixing chamber, to flow out to the ejection opening via one or more throttle passage The drug powder can be squirted into the patient's mouth with enhanced dispersibility.

[Brief description of the drawings]

FIG. 1 is a longitudinal sectional view showing an inhaler type dispenser according to a first embodiment of the present invention.

FIG. 2 is a longitudinal sectional view as seen from the direction of arrows II-II in FIG.

FIG. 3 is a longitudinal sectional view showing a state in which the medicine powder in the capsule is being sucked, as viewed from the same position as in FIG. 1;

FIG. 4 is a longitudinal sectional view showing an inhaler type dispenser according to a second embodiment of the present invention.

It is a longitudinal sectional view seen from the direction V - [5] arrow V in FIG.

FIG. 6 is a cross-sectional view as viewed from a direction indicated by arrows VI - VI in FIG . 4 ;

FIG. 7 is a longitudinal sectional view showing an inhalation type dispenser according to a third embodiment of the present invention.

──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Kazunori Ishiseki 1370 Onna, Atsugi-shi, Kanagawa Prefecture Inside Unisia Jex Co., Ltd. (72) Inventor Yoshiyuki Tanizawa 1370 Onna, Atsugi-shi, Kanagawa Prefecture Inside Unisia Jex Co., Ltd. (72 ) Inventor Akira Yanagawa 5-3 Fujimigaoka, Tsuzuki-ku, Yokohama, Kanagawa Prefecture (56) References JP-A-8-47531 (JP, A) JP-A-60-185564 (JP, A) JP-T-2000-504248 (JP, A) A) Special table Hei 6-509953 (JP, A) International publication 92/771 (WO, A1) (58) Fields investigated (Int. Cl. ⁷ , DB name) A61M 11/00 A61M 13/00 A61M 15 / 00

Claims (4)

(57) [Claims] And 1. A medication body a patient has a suction port for sucking the medicine powder, and medicine powder accommodating chamber Ru extends axially positioned dosage unit body, and a drug powder storage chamber and the atmosphere side an inlet air passage which communicates, at the outflow side air passage and an inhaling type medicine administering device comprising a for communicating the medicine powder accommodating chamber and the suction port, the suction port of the previous SL administering device main body, intake inlet of the middle Located in
A narrowing portion, which is located on the side of the powder storage chamber with the narrowing portion interposed therebetween.
A mixed-chamber you mixed leaked medicine powder from the outlet air passage, ejecting the medicine powder from across the narrowed portion located opposite the said mixing chamber said mixing chamber through the throttle portion and an opening out injection you provided, the outlet-side air passage is inclined obliquely with respect to the drug powder storage chamber
Configuration and communicating the drug powder receiving chamber extends into the mixing chamber
An inhaling type medicine administering device you characterized in that the. 2. The dispenser main body is provided with an auxiliary air passage that communicates the mixing chamber formed by the throttle section with the atmosphere side separately from a passage composed of the inflow-side air passage and the outflow-side air passage. The inhaler-type dispenser according to claim 1. 3. The mixing passage according to claim 2, wherein an opening portion of the auxiliary ventilation passage is formed obliquely with respect to a wall surface of the mixing chamber so that air flowing out of the auxiliary ventilation passage into the mixing chamber is swirled. Inhalation type dispenser. 4. The inhaler-type dispenser according to claim 1, wherein said throttle portion is constituted by one or a plurality of throttle passages.