JPH11299892A - Inhalation type medicine administration device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To form an air stream corresponding to the characteristics of a powder medicine and to efficiently administer the powder medicine of different characteristics to a patient by one medicine administration device. SOLUTION: A capsule holder 2 is provided with a capsule moving body guide hole 3 and a capsule moving body 10 for holding a capsule is movably provided in the capsule moving body guide hole 3. Thus, by moving the capsule by the capsule moving body 10, since the separating dimension of an inflow hole and an outflow hole formed on the capsule by the pin 18 of a piercing tool 16 is appropriately set corresponding to the characteristics of the powder medicine filled inside the capsule, the dispersibility of the powder medicine inside the capsule is improved. Thus, since one medicine administration device is separately and properly used corresponding to the characteristics of the powder medicine, handling on medicine administering work is facilitated and the burdens of the patient are reduced.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an inhalation type dispenser suitable for administering a powdered drug (medicine powder) into the lungs by inhaling a patient's breath, for example.

[0002]

2. Description of the Related Art In general, a method of administering a drug to the lungs of an asthma patient or the like includes a method of inhaling with a liquid aerosol sprayer, a powdery drug filled in a drug powder accommodating hole or a capsule (hereinafter referred to as a drug powder). Is used.

[0003] Among these drug administration methods for asthma patients,
As an inhalation type dispenser used in a method of inhaling a medicinal powder filled in a medicinal powder accommodating hole or the like, the one shown in JP-A-7-313599 is known. In the inhalation type dispenser according to the related art, one side in the axial direction is a capsule accommodation hole for accommodating a capsule filled with the medicinal powder, and the other side is an inhalation port, and the dispenser main body is accommodated in the capsule accommodation hole. In order to supply the powdered medicine in the capsule to the suction port side, a hole is formed in the capsule accommodated in the capsule accommodation hole, and a ventilation path communicating the atmosphere side and the suction port side via the capsule accommodation hole. For this purpose, a piercing tool provided in the dispenser body is provided.

In this inhaler type dispenser, a capsule filled with a medicinal powder is inserted into a capsule receiving hole, and a hole communicating with an air passage is formed in the capsule by a punch. In this state, the air is sucked into the capsule from the atmosphere side through the ventilation path on the inflow side by sucking the inhalation port and the medicine powder in the capsule is diffused by the air flow. Then, the medicine powder diffused by the air flow is discharged to the inhalation port side through the outflow-side ventilation path, and is inhaled into the lungs of the patient from the inhalation port.

[0005]

By the way, in the above-mentioned inhalation type dispenser according to the prior art, the medicine powder is diffused by the air flow flowing into the capsule through the inflow side air passage. However, the chemical powder has various characteristics (fluidity, dispersibility), such as granules having strong cohesion and powders easily charged with static electricity.

Therefore, in order to administer medicine powders having different characteristics, an air flow (turbulent flow) corresponding to each characteristic must be formed in the capsule. Therefore, it is necessary to selectively use a plurality of types of dispensers having different specifications such as air passages, for example, a dispenser using agglomerated granules as a medicinal powder, a dispenser using a powder easily charged with static electricity, and the like. There is a problem that the dispensing operation becomes troublesome, and the patient must own two or three dispensers, which increases the burden on the patient.

[0007] The present invention has been made in view of the above-mentioned problems of the prior art, and an object of the present invention is to form an air flow according to the characteristics of a medicinal powder, and to provide a medicinal powder having different characteristics in one dispenser. Is to provide an inhalation-type dispenser capable of efficiently administering to a patient.

[0008]

In order to solve the above-mentioned problems, in the inhalation type dispenser adopted in the first aspect of the present invention, one side in the axial direction is a guide hole for a capsule moving body, and the other side is a suction port. A dispensing device main body, a capsule moving body movably provided in a capsule moving body guide hole of the dispensing device main body, the capsule moving body having a capsule holding portion for holding a capsule; and An air passage for circulating toward the suction port via a capsule held by a capsule holding unit of the capsule moving body, provided in the dispenser main body,
The capsule moving body is constituted by a drilling tool for drilling a hole communicating with the ventilation path in the capsule held by the capsule holding section.

With this configuration, the capsule is held in the capsule holding portion of the capsule moving body, and in this state, the capsule moving body is moved by the capsule moving body guide hole, so that the capsule is moved with respect to the drilling tool. The capsule can be moved, and the piercing device can pierce a desired position of the capsule, for example, a position at which an air flow according to the characteristics of the medicinal powder is formed in the capsule. Thereby, when breath is inhaled in addition to the inhalation port, the air flow flowing into the capsule through the hole from the air passage can be made to be an air flow according to the characteristics of the chemical powder. The medicament powder in the capsule is dispersed and atomized, and can be stably inhaled into the lung from the inhalation port.

A second aspect of the present invention is that the capsule moving body is configured to move the capsule held by the capsule holding section to a desired position by an operation from the outside of the dispenser body. Thereby, the capsule moving body can be moved from the outside of the dispenser main body, and the hole of the capsule can be formed at a position corresponding to the characteristics of the medicine powder by a simple operation.

The invention according to claim 3 is that the piercing tool is constituted by one piercing pin provided movably in the radial direction of the dispenser main body. Thereby, the configuration of the punch and the dispenser main body can be simplified.

A fourth aspect of the present invention resides in that a scale is provided on the outer peripheral surface of the main body of the dispenser, and a marker portion which moves along the scale is provided on the capsule moving body. Thereby, the position of the hole in the capsule can be confirmed from the outside by the scale and the marker portion.

[0013]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, an inhaler type dispenser according to an embodiment of the present invention will be described in detail with reference to FIGS.

Reference numeral 1 denotes a main body of a dispenser serving as a base of the inhaler type dispenser. The main body 1 is generally constituted by a capsule holder 2 and a suction port 7, which will be described later.

Reference numeral 2 denotes a capsule holder provided on one side of the dispenser main body 1. The capsule holder 2 is formed in a substantially cylindrical shape as shown in FIG. 3 (hereinafter, referred to as a moving body guide hole 3) is formed as an elongated hole extending in the axial direction. The moving body guide hole 3 is formed to have a diameter slightly larger than the diameter of a capsule K described later, one end of which is open to the atmosphere and the other end is a bottomed hole serving as a bottom. And
The moving body guide hole 3 guides a capsule moving body 10 described later so as to be movable together with the capsule K.

Here, the capsule K is formed in a long cylindrical shape in which both ends in the length direction are convex spherical, and a powdery chemical (hereinafter referred to as a chemical powder) is contained inside the capsule K. Is filled.

On the outer peripheral side of the capsule holder 2, a support cylinder portion 4 for movably supporting a support portion 17 of a drilling tool 16, which will be described later, is provided so as to project radially outward. Further, a pin insertion hole 5 is formed in the support cylindrical portion 4 so as to radially penetrate the movable body guide hole 3, and the pin 18 of the hole punch 16 is movably inserted into the pin insertion hole 5. .

Reference numeral 6 denotes a moving groove provided in the capsule holder 2, and the moving groove 6 is orthogonal to the pin insertion hole 5 and extends along the moving body guide hole 3, as shown in FIGS. And extend in the axial direction. The moving groove 6 allows the holding rod 12, the operating lever 13, and the like of the capsule moving body 10 described later to move.

Reference numeral 7 denotes a suction port which is detachably attached to the other end of the capsule holder 2. The suction port 7 is formed in a substantially cylindrical shape, and the outer periphery at the other end is directed to the other side so that the patient can easily hold it. The diameter is gradually reduced.

Reference numerals 8, 8 denote two inflow-side ventilation passages provided on one side of the capsule holder 2. Each of the inflow-side ventilation passages 8 is located on the outer peripheral side of the movable body guide hole 3, and Axial passages 8A, 8A extending in the axial direction of the capsule holder 2 so as to open to the atmosphere from one side end surface, and communicating with the axial passages 8A, and a moving body guide hole near the pin insertion hole 5. 3
Radial passages 8B, 8B extending radially to open
And is constituted by. And each inflow side ventilation passage 8
Is for communication between the inside of the capsule K and the atmosphere side.

Reference numerals 9 and 9 denote two outflow-side air passages provided on the other side of the capsule holder 2. Each of the outflow-side air passages 9 is located on the outer peripheral side of the movable body guide hole 3. Axial passages 9A, 9A extending in the axial direction of the capsule holder 2 so as to open from the other end surface to the suction port 7, communicate with the respective axial passages 9A, and move near the pin insertion hole 5. A radial passage 9B extending in the radial direction so as to open to the guide hole 3;
9B. Each outflow-side ventilation path 9 communicates the inside of the capsule K with the suction port 7 side.

Reference numeral 10 denotes a movable body guide hole 3 of the capsule holder 2.
As shown in FIG. 6, the capsule moving body 10 includes a capsule receiver 11 slidably inserted into the moving body guide hole 3 and a capsule receiving body which is slidably inserted into the moving body guide hole 3. Two holding rods 12, 12 fixed to the outer periphery of the receiver 11, the leading ends of which extend to one side in the axial direction and become free ends, and are fixed to the leading end of one of the holding rods 12 of the holding rods 12. ,
An operation lever 13 extending radially toward the outer surface side of the capsule holder 2 and a marker projection 14 as a triangular prism-shaped marker portion extending radially from the middle of the holding rod 12 parallel to the operation lever 13. It is configured.

Here, the capsule receiver 11 is formed in a short columnar shape, and has a concave spherical fitting recess 11A into which an end of the capsule K is fitted on one side surface. Each holding rod 12 is slidably supported by the moving groove 6, and an arc-shaped holding projection 12A for holding the capsule K between the holding rod 12 and the fitting recess 11A of the capsule receiver 11 is opposed to the tip end thereof. It is formed. Thus, the capsule receiver 11 and each holding rod 1
2 form a capsule holding unit. further,
The operation lever 13 extends in the moving groove 6 in the radial direction, and an operation piece 13A for operating the capsule moving body 10 from the outside is provided at a tip portion thereof.

Then, as shown by a two-dot chain line in FIG.
A and the capsule K between the holding projection 12A of each holding rod 12
Is held, the capsule K is moved in the arrow A direction or the arrow B direction from the outside of the capsule holder 2 via the operation piece 13A of the operation lever 13. Also,
The moving position of the capsule K can be confirmed by the marker protrusion 14 moving along the scale 15 (shown in FIG. 1) provided on the outer peripheral surface of the capsule holder.

On the other hand, reference numeral 16 denotes a piercing tool for piercing the capsule K held by the capsule moving body 10. The piercing tool 16 comprises a support 17 movably supported in the support cylinder 4, and a base 17. One end 18 is fixed to the support portion 17 and one end 18 is inserted into the pin insertion hole 5 with a sharp tip at the tip end, and is provided between the support portion 17 and the capsule holder 2. It is roughly constituted by the return spring 19.

The drilling tool 16 pushes the support portion 17 into the support tube portion 4 against the return spring 19,
The needle point of the pin 18 is made to penetrate the capsule K held by the capsule moving body 10, and an inflow hole H 1 described later is inserted into the capsule K.
, H1 and outflow holes H2, H2. When the pressing force on the support portion 17 is removed, the support portion 17 and the pins 18 are retracted to the standby position by the urging force of the return spring 19.

The inhaler-type dispenser according to the present embodiment has the above-mentioned configuration. Next, the preparation operation until the patient inhales the medicinal powder and the flow of air and medicinal powder during inhalation are shown in FIGS. This will be described with reference to FIG.

First, the preparation operation until the inflow hole H1 and the outflow hole H2 are formed in the capsule K will be described.

First, with the capsule K held by the capsule moving body 10, the capsule K is inserted into the moving body guide hole 3 together with the capsule moving body 10. Next, the capsule K is moved in the direction of arrow A by the capsule moving body 10 while viewing the marker projection 14 and the scale 15, and the movement of the capsule K is stopped at a predetermined position as shown in FIG. Then, in this state, the supporting portion 17 of the drilling tool 16 is pushed and the pin 18 is moved.
Are penetrated through the capsule K, so that the inflow holes H1, H1 are made in the capsule K.

Next, the capsule K is moved in the direction of arrow B by the capsule moving body 10, and the movement of the capsule K is stopped at a predetermined position as shown in FIG. Then, in this state, the outflow hole H2
, H2.

Here, the distance L between each of the inflow holes H1 and each of the outflow holes H2 formed in the capsule K is determined by the characteristics of the chemical powder filled in the capsule K, for example, granules having strong cohesion, static electricity, It is appropriately set in accordance with the fluidity and dispersibility depending on the condition of a powder or the like which is apt to take on. When the distance L is set to be large, a turbulent flow occurs at one point in the capsule K, and when the distance L is set to be small, the capsule K
A turbulent flow will be generated at two places.

After each outflow hole H2 is formed in the capsule K, the capsule K is moved in the direction of arrow A by the capsule moving body 10, and the inflow hole H1 communicates with the inflow side ventilation passage 8 as shown in FIG. The outlet hole H2 is communicated with the outlet side ventilation path 9.

Next, the flow of air and powder in the inhaler-type dispenser when the patient inhales the medicine will be described.

First, the patient holds the other end of the suction port 7,
Inhale in this state. As a result, the air (atmosphere) flows toward the capsule K through each inflow side ventilation passage 8 and flows into the capsule K via each inflow hole H1. At this time, the air flow that has flowed into the capsule K from each of the inflow side ventilation paths 8 disperses the chemical powder in the capsule K.

Then, the chemical powder mixed into the air in the capsule K is discharged from each outflow hole H2 through each outflow side ventilation path 9 to the suction port 7 side. As a result, the patient is
Can be administered to the lungs via the mouth and trachea by inhaling the drug powder released from.

Here, the distance L between the inflow hole H1 and the outflow hole H2 of the capsule K is appropriately set in accordance with the characteristics of the powder in the capsule K. A turbulent flow can be formed, and the chemical powder can be stably supplied to the suction port 7 side in a state of being dispersed by the turbulent flow.

As described above, according to the present embodiment, the distance L between the inflow hole H1 and the outflow hole H2 formed in the capsule K is appropriately determined according to the characteristics of the chemical powder filled in the capsule K. Therefore, the dispersibility of the medicinal powder in the capsule K can be improved. Thus, one medication device can be used selectively according to the characteristics of the medicinal powder, so that handling during medication operation can be facilitated. Moreover, the patient only needs to have one dispenser, and the burden on the patient can be reduced.

The operation lever 1 is attached to the capsule moving body 10.
3, the capsule K is moved by operating the operation piece 13A of the operation lever 13 from the outside. Therefore, the capsule K can be easily moved by the operation lever 13, and the operability at the time of administration is improved. Can be improved.

Further, since the moving position of the capsule K can be confirmed by the marker projection 14 and the scale 15,
The inflow hole H1 and the outflow hole H2 can be accurately and easily formed in the capsule K, and the dispersibility of the medicinal powder, the operability of the dispenser, and the like can be improved.

Further, since the drilling tool 16 has one pin 18, the number of parts can be reduced and the configuration can be simplified.
The entire dispenser can be reduced in size.

In the embodiment, the capsule moving body 1
0, a marker projection 14 is provided.
5, the moving position of the capsule K is confirmed. However, the present invention is not limited to this.
A marker may be provided on the operation piece 13A, and a scale 15 may be provided corresponding to the marker. In this case, the marker projection 14 can be omitted.

[0042]

As described in detail above, according to the first aspect of the present invention, the capsule moving body guide hole is provided in the dispenser main body, and the capsule moving body has the capsule holding portion in the capsule moving body guide hole of the dispenser main body. Is movably provided, the capsule is held in the capsule holding portion of the capsule moving body, and the capsule moving body is moved in the capsule moving body guide hole in this state, thereby moving the capsule with respect to the drilling tool. The piercing device can pierce a desired position of the capsule, for example, a position at which an air flow according to the characteristics of the medicinal powder is formed in the capsule.

Thus, when breath is inhaled in addition to the suction port, the air flow flowing into the capsule from the air passage through the hole can be made an air flow according to the characteristics of the chemical powder. The medicine powder in the capsule is dispersed and atomized by the air flow, and can be stably inhaled into the lung from the inhalation port. As a result, a single dispenser can be selectively used according to the characteristics of the medicinal powder, so that handling during the dispensing operation can be facilitated. Moreover, the patient only needs to have one dispenser, and the burden on the patient can be reduced.

According to the second aspect of the present invention, the capsule moving body is configured to move the capsule held by the capsule holding portion to a desired position by an operation from outside the dispenser main body. By moving the capsule moving body from the outside, the hole of the capsule can be formed at a position corresponding to the characteristics of the medicinal powder by a simple operation, and the handleability can be improved.

According to the third aspect of the present invention, since the piercing device is constituted by a single piercing pin provided so as to be movable in the radial direction of the dispensing device main body, the configuration of the piercing device and the dispensing device main body is simplified. It is possible to improve the assemblability, downsize the inhalation type dispenser, and the like.

According to the fourth aspect of the present invention, the scale is provided on the outer peripheral surface of the main body of the dispenser, and the marker portion which moves along the scale is provided on the capsule moving body. The parts can be checked from the outside, and the drilling operation can be facilitated.

[Brief description of the drawings]

FIG. 1 is a front view showing an inhalation type dispenser according to an embodiment of the present invention.

FIG. 2 is a longitudinal sectional view showing an inhalation type dispenser according to an embodiment of the present invention.

FIG. 3 is a right side view showing the inhaler type dispenser.

FIG. 4 is a cross-sectional view as viewed from the direction of arrows IV-IV in FIG. 2;

FIG. 5 is a vertical cross-sectional view as seen from a direction indicated by arrows VV in FIG. 2;

FIG. 6 is an external perspective view showing an enlarged capsule moving body.

FIG. 7 is an enlarged longitudinal sectional view showing a main part of a state in which an inflow hole is formed in a capsule.

FIG. 8 is an enlarged longitudinal sectional view of a main part viewed from the same position as in FIG. 7, showing a state in which an outflow hole is formed in the capsule.

FIG. 9 is a longitudinal sectional view showing the inhaler-type dispenser in a state where the medicine powder in the capsule is inhaled, as viewed from the same position as in FIG. 2;

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Dosing device main body 2 Capsule holder 3 Capsule moving body guide hole 7 Inlet 8 Inlet side ventilation path 9 Outlet side ventilation path 10 Capsule moving body 11 Capsule receiving part (capsule holding part) 12 Holding rod (capsule holding part) 13 Operating lever 14 Marker protrusion (marker part) 15 scale 16 Drilling tool 18 pin K capsule H1 Inflow hole H2 Outflow hole

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Inventor Shigemi Nakamura 1370 Onna, Atsugi-shi, Kanagawa Prefecture Inside Unisia Gex Co., Ltd. (72) Inventor Kazunori Ishiseki 1370 Onna, Atsugi-shi, Kanagawa Prefecture Inside Unisia Gex Co., Ltd. (72) Inventor Akira Yanagawa 5-3 Fujimigaoka, Tsuzuki-ku, Yokohama, Kanagawa

Claims (4)

[Claims] 1. A dispenser main body having one axial side serving as a capsule moving body guide hole and the other side serving as an inlet, and a capsule moving body guide hole of the dispenser main body movably provided to hold a capsule. A capsule moving body having a capsule holding portion, and an air passage provided in the dispenser main body, for allowing external air to flow toward the suction port through a capsule held in the capsule holding portion of the capsule moving body, An inhalation-type dispenser which is provided on the dispenser main body and comprises a drilling tool for drilling a hole communicating with the air passage in a capsule held in a capsule holding portion of the capsule moving body. 2. The inhaler-type dispenser according to claim 1, wherein the capsule moving body is configured to move the capsule held by the capsule holder to a desired position by an operation from outside the dispenser main body. . 3. The inhalation type dispenser according to claim 1, wherein the piercing tool is constituted by one piercing pin movably provided in a radial direction of the dispenser main body. 4. The inhalation type medication according to claim 1, wherein a scale is provided on an outer peripheral surface of said dispenser main body, and a marker portion which moves along said scale is provided on said capsule moving body. vessel.