WO2024086856A3 - Système d'automatisation de processus analytiques chimiques et biologiques - Google Patents

Système d'automatisation de processus analytiques chimiques et biologiques Download PDF

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Publication number
WO2024086856A3
WO2024086856A3 PCT/US2023/081407 US2023081407W WO2024086856A3 WO 2024086856 A3 WO2024086856 A3 WO 2024086856A3 US 2023081407 W US2023081407 W US 2023081407W WO 2024086856 A3 WO2024086856 A3 WO 2024086856A3
Authority
WO
WIPO (PCT)
Prior art keywords
shuttle
automate
processes
chambers
chemical
Prior art date
Application number
PCT/US2023/081407
Other languages
English (en)
Other versions
WO2024086856A2 (fr
Inventor
Dennis M. Connolly
Original Assignee
Next Labs, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Next Labs, Llc filed Critical Next Labs, Llc
Publication of WO2024086856A2 publication Critical patent/WO2024086856A2/fr
Publication of WO2024086856A3 publication Critical patent/WO2024086856A3/fr

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0303Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50855Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0642Filling fluids into wells by specific techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0357Sets of cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0367Supports of cells, e.g. pivotable
    • G01N2021/0371Supports combined with sample intake
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0367Supports of cells, e.g. pivotable
    • G01N2021/0375Slidable cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La présente invention concerne un nouveau système constitué d'un lecteur et d'une cartouche jetable servant à automatiser des processus analytiques chimiques et biologiques complexes. Le système peut automatiser de nombreux processus de laboratoire standard. La cartouche comprend une navette qui se déplace le long d'un rail dans un boîtier. La navette se déplace de façon linéaire, une étape par étape, durant le processus. La navette est constituée de chambres de réaction et de réactifs. Des seringues dans le boîtier sont en communication fluidique avec les chambres et sont utilisées pour déplacer des fluides dans et hors des chambres. La conception de la cartouche est flexible, ce qui permet l'automatisation d'un grand nombre de processus complexes. En particulier, la présente invention concerne un système permettant d'automatiser toutes les étapes nécessaires à l'isolation et à la préparation d'acides nucléiques à des fins d'analyse.
PCT/US2023/081407 2022-10-19 2023-11-28 Système d'automatisation de processus analytiques chimiques et biologiques WO2024086856A2 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US202263380137P 2022-10-19 2022-10-19
US63/380,137 2022-10-19
US202363480056P 2023-01-16 2023-01-16
US202363480050P 2023-01-16 2023-01-16
US63/480,056 2023-01-16
US63/480,050 2023-01-16
US202363443235P 2023-02-03 2023-02-03
US63/443,235 2023-02-03

Publications (2)

Publication Number Publication Date
WO2024086856A2 WO2024086856A2 (fr) 2024-04-25
WO2024086856A3 true WO2024086856A3 (fr) 2024-06-06

Family

ID=90738440

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/081407 WO2024086856A2 (fr) 2022-10-19 2023-11-28 Système d'automatisation de processus analytiques chimiques et biologiques

Country Status (1)

Country Link
WO (1) WO2024086856A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6374684B1 (en) * 2000-08-25 2002-04-23 Cepheid Fluid control and processing system
US20120244534A1 (en) * 2004-10-27 2012-09-27 Cephied Closed-system multi-stage nucleic acid amplification reactions
US8663918B2 (en) * 2009-05-22 2014-03-04 Integrated Nano-Technologies, Inc. Method and system for sample preparation
US20160186240A1 (en) * 2014-12-31 2016-06-30 Click Diagnostics Devices and methods for molecular diagnostic testing

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6374684B1 (en) * 2000-08-25 2002-04-23 Cepheid Fluid control and processing system
US20120244534A1 (en) * 2004-10-27 2012-09-27 Cephied Closed-system multi-stage nucleic acid amplification reactions
US8663918B2 (en) * 2009-05-22 2014-03-04 Integrated Nano-Technologies, Inc. Method and system for sample preparation
US20160186240A1 (en) * 2014-12-31 2016-06-30 Click Diagnostics Devices and methods for molecular diagnostic testing

Also Published As

Publication number Publication date
WO2024086856A2 (fr) 2024-04-25

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