WO2024076029A1 - Dispositif de mesure de température dans un réseau d'électrodes - Google Patents

Dispositif de mesure de température dans un réseau d'électrodes Download PDF

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Publication number
WO2024076029A1
WO2024076029A1 PCT/KR2023/013743 KR2023013743W WO2024076029A1 WO 2024076029 A1 WO2024076029 A1 WO 2024076029A1 KR 2023013743 W KR2023013743 W KR 2023013743W WO 2024076029 A1 WO2024076029 A1 WO 2024076029A1
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Prior art keywords
temperature
temperature measurement
measurement module
electrode array
control unit
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PCT/KR2023/013743
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English (en)
Korean (ko)
Inventor
홍진영
이동준
강우정
김종현
Original Assignee
주식회사 필드큐어
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Priority claimed from KR1020230115095A external-priority patent/KR20240049147A/ko
Application filed by 주식회사 필드큐어 filed Critical 주식회사 필드큐어
Publication of WO2024076029A1 publication Critical patent/WO2024076029A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

Definitions

  • the present invention relates to a device for measuring temperature in an electrode array, and more specifically, to a device for measuring temperature in an electrode array in which the interface cable with the electrode array is minimized.
  • TFields Tumor Treatment Fields (TTFields), which induces tumor cell death by delivering an alternating electric field to the tumor, is a proven cancer treatment method that has obtained FDA approval for relapsed glioblastoma and newly diagnosed glioblastoma.
  • An electric field tumor treatment system for delivering a therapeutic electric field to a target area of an object consists of a generator (alternating current signal generator), a distributor, and a plurality of electrode arrays.
  • each electrode array consists of a plurality of electrode elements attached to the surface of an object.
  • a typical electrode array for brain tumors (Glioblastoma) consists of 9 capacitively coupled individual electrodes in a 3X3 matrix structure, and a temperature sensor can be added to each individual electrode to measure the temperature between the electrode and the skin.
  • the generator is connected via a distributor to two pairs of electrode arrays to cover two mutually orthogonal directions.
  • the distributor connects the first electrode array pair to flow current for a certain period of time, and then selects the second electrode array pair to flow current for a certain period of time.
  • the current generated from the generator is connected to the selected electrode array pair through a distributor, and is connected to the electrodes of the first electrode array and the skin and body of the subject to which the electrodes are attached, the skin of the subject to which the electrodes of the second electrode array are attached, the The current flows along the current path created by the electrodes of the second electrode array.
  • a therapeutic electric field of a certain intensity or higher is delivered to the target area of the cancer cells, and this therapeutic electric field destroys the cancer cells by interfering with or delaying the division of dividing cancer cells.
  • the interface cable between the electrode array and the distributor is very complex, consisting of a conductor for the current path, an analog signal line for outputting the temperature measurement value to the generator, and additional lines for the temperature measurement circuit.
  • a conductor for the current path As an alternating current of hundreds of kHz or more than 1A flows, a change in the magnetic field occurs around the conductor for the current path, and this change causes unnecessary interference in the temperature analog output line, which can cause problems with accurate temperature measurement.
  • U.S. Patent No. 11,097,101 and Korean Patent Publication No. 10-2020-0008542 measure temperature within the electrode array using an analog multiplex, constant current source, analog-to-digital converter (ADC), and controller. A method of sequentially measuring temperature and digitally outputting the measured temperature value is disclosed.
  • U.S. Patent Publication No. 2022-0193404 extends this method and discloses a method of selecting a temperature sensor using a matrix switching method using two analog multiplexes and controlling the current waveform of the generator based on the measured temperature value. do.
  • U.S. Patent Publication No. 2022-0257927 discloses a method of switching each electrode array based on the temperature of four or more electrode arrays.
  • the purpose of the present invention to solve the above problems is to provide a device for measuring temperature in an electrode array in which the interface cable with the electrode array is minimized.
  • a temperature measuring device in an electrode array is attached to the surface of an object and transmits an electric field to the object, comprising: the electrode A plurality of electrodes 1100 mounted on an array to transmit an electric field to the object; A plurality of temperature measurement modules 1200 for measuring the temperature between the plurality of electrodes 1100 and the surface of the object; And a digital control unit ( 1300); may be included.
  • each temperature measurement module includes a temperature sensor 1210 for measuring temperature; A conversion unit 1220 that converts the measured temperature value into a digital signal; A receiving unit 1230 that receives a digital signal; A transmitter 1240 that transmits a digital signal; And a temperature measurement module control unit 1250 for controlling the temperature sensor 1210, conversion unit 1220, receiver 1230, and transmitter 1240,
  • the temperature measurement module control unit 1250 measures the temperature through the temperature sensor 1210 according to the measurement signal received through the receiver 1230, and converts the measured temperature value to the conversion unit 1220. Converting to a temperature value signal through, and providing the converted temperature value signal through the transmitting unit 1240,
  • the temperature measurement module control unit 1250 combines the received measurement signal and the temperature value signal converted from the measured temperature value to form one data sequence, and then converts the one data sequence into the The temperature measurement module 1200 may be provided externally.
  • the measurement signal received from the temperature measurement module 1200 includes the converted temperature value signal of at least one adjacent temperature measurement module in addition to the temperature measurement command,
  • the digital control unit 1300 and the plurality of temperature measurement modules 1200 are connected in series, and the position information and temperature value of each temperature measurement module 1200 are determined by analyzing the response signal received by the digital control unit 1300. It could be identification.
  • each temperature measurement module includes a temperature sensor 1210 for measuring temperature; A conversion unit 1220 that converts the measured temperature value into a digital signal; A receiving unit 1230 that receives a digital signal; A transmitter 1240 that transmits a digital signal; And a temperature measurement module control unit 1250 for controlling the temperature sensor 1210, conversion unit 1220, receiver 1230, and transmitter 1240,
  • the temperature measurement module control unit 1250 measures the temperature through the temperature sensor 1210 according to the measurement signal received through the receiver 1230, and converts the measured temperature value to the conversion unit 1220. Converting to a temperature value signal through, and providing the converted temperature value signal through the transmitting unit 1240,
  • the temperature measurement module control unit 1250 combines the received measurement signal and the temperature value signal converted from the measured temperature value to form one data sequence, and then converts the one data sequence into the The temperature measurement module 1200 may be provided externally.
  • the digital control unit 1300 has a plurality of communication ports, each communication port representing the location information of one temperature measurement module 1200, and the corresponding location by analyzing the response signal received through each communication port. It may be to identify the temperature value of .
  • the digital control unit 1300 sets a temperature measurement cycle, monitors the temperature measurement value of the temperature measurement module in real time according to the temperature measurement cycle, and the monitored temperature measurement value falls within a preset temperature range. If it exceeds this, the location information of the temperature measurement module and the monitored temperature measurement value may be provided to the outside.
  • the digital control unit 1300 sets a temperature measurement cycle, monitors the temperature measurement value of the temperature measurement module in real time according to the temperature measurement cycle, and changes the rate of change of the monitored temperature measurement value to a preset change rate. If the range is exceeded, the location information of the temperature measurement module, the monitored temperature measurement value, and the rate of change may be provided to the outside.
  • the electrode array may be made of a flexible substrate and may be attached to adapt to the curved surface of the object.
  • the digital control unit 1300 may further include a power line communication unit (not shown) that transmits digital data received from the temperature measurement module 1200 using power line communication.
  • a power line communication unit (not shown) that transmits digital data received from the temperature measurement module 1200 using power line communication.
  • a high-frequency alternating current signal generator (not shown) that generates an alternating current voltage of 50 to 500 kHz may be further included.
  • a temperature measuring device in an electrode array for solving the above problems is attached to the surface of an object and transmits an electric field to the object, comprising: the electrode A plurality of electrodes 1100 mounted on an array to transmit an electric field to the object; A plurality of temperature measurement modules 1200 for measuring the temperature between the plurality of electrodes and the surface of the object; And a digital control unit 1300 that connects the plurality of temperature measurement modules 1200 to transmit a digital signal to control each temperature measurement module 1200 and receives a response signal from each temperature measurement module 1200,
  • Each of the temperature measurement modules 1200 includes a temperature sensor 1210 for measuring temperature; A conversion unit 1220 that converts the measured temperature value into a digital signal; A receiving unit 1230 that receives a digital signal; A transmitter 1240 that transmits a digital signal; And a temperature measurement module control unit 1250 for controlling the temperature sensor 1210, conversion unit 1220, receiver 1230, and transmitter 1240.
  • a unique identifier is assigned to the temperature sensor 1210, and the temperature measurement module control unit 1250 measures the temperature through the temperature sensor 1210 according to the measurement signal received through the receiver 1230. , converting the measured temperature value into a temperature value signal through the converter 1220, and providing the converted temperature value signal through the transmitter 1240,
  • the temperature measurement module control unit 1250 combines the unique identifier, the received measurement signal, and the temperature value signal converted from the measured temperature value to form one data sequence, and then The data sequence may be provided to the outside of the temperature measurement module 1200.
  • the interface cable between the electrode array and distributor for conventional electric field tumor treatment includes a current pass for flowing current to each individual electrode, a power line for a temperature measurement circuit to measure the temperature between the electrode and the skin, and a power line for sending temperature measurement values. Numerous wires, including analog signal wires, are needed.
  • the present invention discloses a method and device for sequentially digitally measuring temperature sensors provided in an electrode array in a daisy chain and outputting these measured values.
  • the interface cable between the electrode array and the distributor includes a conductor for a current path and a temperature sensor. It can consist of only two conductors for power supply. This has the advantage of reducing the complexity of circuits and interface cables for measuring the temperature of each electrode in the electric field therapy electrode array.
  • FIG. 1 is a diagram for explaining a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • Figure 2 is a diagram for explaining a temperature measuring device in an electrode array according to another embodiment of the present invention.
  • Figure 3 is a diagram for explaining the temperature measurement module in the temperature measurement device in the electrode array according to an embodiment of the present invention.
  • Figure 4 is a block diagram of a temperature sensor with a serial interface and supporting a daisy chain structure in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • FIG. 5 is a diagram of a host controller for transmitting a command to a plurality of temperature sensors configured in a daisy chain and receiving temperature measurement data in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • Figure 6 is a diagram showing a host controller for serial communication with a generator or distributor in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • FIG. 7 is a diagram illustrating a host controller for power line communication with a generator or distributor in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • Figure 8 is a diagram showing a plurality of electrodes, a temperature sensor, a communication controller, and a cable constituting a typical 3X3 electrode pad in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • first, second, and third are used to describe, but are not limited to, various parts, components, regions, layers, and/or sections. These terms are used only to distinguish one part, component, region, layer or section from another part, component, region, layer or section. Accordingly, the first part, component, region, layer or section described below may be referred to as the second part, component, region, layer or section without departing from the scope of the present invention.
  • FIG. 1 is a diagram for explaining a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • Figure 2 is a diagram for explaining a temperature measuring device in an electrode array according to another embodiment of the present invention.
  • Figure 3 is a diagram for explaining the temperature measurement module in the temperature measurement device in the electrode array according to an embodiment of the present invention.
  • Figure 4 is a block diagram of a temperature sensor with a serial interface and supporting a daisy chain structure in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • FIG. 5 is a diagram of a host controller for transmitting a command to a plurality of temperature sensors configured in a daisy chain and receiving temperature measurement data in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • FIG. 6 is a diagram showing a host controller for serial communication with a generator or distributor in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • FIG. 7 is a diagram illustrating a host controller for power line communication with a generator or distributor in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • Figure 8 is a diagram showing a plurality of electrodes, a temperature sensor, a communication controller, and a cable constituting a typical 3X3 electrode pad in a temperature measuring device in an electrode array according to an embodiment of the present invention.
  • a temperature measuring device 1000 in an electrode array is attached to the surface of an object and measures the temperature in the electrode array for transmitting an electric field to the object.
  • the device 1000 includes a plurality of electrodes 1100 mounted on the electrode array to transmit an electric field to the object; A plurality of temperature measurement modules 1200 for measuring the temperature between the plurality of electrodes 1100 and the surface of the object; And a digital control unit ( 1300); may be included.
  • the electrode array is used to transmit an electric field to the object, and may be attached to the surface of the object, and may be equipped with the plurality of electrodes 1100.
  • the plurality of electrodes 1100 may be mounted on the electrode array to transmit an electric field to the object.
  • the plurality of electrodes 1100 may be mounted on the electrode array in various arrangements in consideration of the efficiency of electric field transmission.
  • the plurality of temperature measurement modules 1200 may be used to measure the temperature between the surface of the object, and may be used to measure the temperature between the plurality of electrodes 1100 and the surface of the object.
  • the digital control unit 1300 is connected to the plurality of temperature measurement modules 1200 and transmits a digital signal to control each temperature measurement module 1200, and a response signal of each temperature measurement module 1200. It may be receiving.
  • each temperature measurement module (1200) is a temperature sensor (1210) for measuring temperature;
  • a conversion unit 1220 that converts the measured temperature value into a digital signal;
  • a receiving unit 1230 that receives a digital signal;
  • a transmitter 1240 that transmits a digital signal; and
  • a temperature measurement module control unit 1250 for controlling the temperature sensor 1210, conversion unit 1220, receiver 1230, and transmitter 1240.
  • the temperature measurement module control unit 1250 measures the temperature through the temperature sensor 1210 according to the measurement signal received through the receiver 1230, and converts the measured temperature value to the conversion unit 1220. ) is converted into a temperature value signal, and the converted temperature value signal is provided through the transmitter 1240,
  • the temperature measurement module control unit 1250 combines the received measurement signal and the temperature value signal converted from the measured temperature value to form one data sequence, and then converts the one data sequence into the The temperature measurement module 1200 may be provided externally.
  • the plurality of temperature measurement modules 1200 are connected in series with the digital control unit 1300, and the temperature measurement module control unit 1250 is connected to the reception unit 1230.
  • the temperature is measured through the temperature sensor 1210, the measured temperature value is converted into a temperature value signal through the converter 1220, and the converted temperature value signal is is provided through the transmitter 1240, and the temperature measurement module control unit 1250 combines the received measurement signal and the temperature value signal converted from the measured temperature value to form one data sequence. After being formed, the single data sequence may be provided to the outside of the temperature measurement module 1200.
  • the digital control unit 1300 receives the one data sequence, and when the one data sequence is analyzed, the temperature measured for each temperature measurement module 1200 in the plurality of temperature measurement modules 1200 It will be possible to determine the temperature measured by the temperature measurement module 1200.
  • the measurement signal received from the temperature measurement module 1200 includes a converted temperature value signal of at least one adjacent temperature measurement module in addition to a temperature measurement command, and the digital control unit 1300 and the plurality of temperature measurement modules 1200 may be connected in series to identify the location information and temperature value of each temperature measurement module 1200 by analyzing the response signal received by the digital control unit 1300.
  • each temperature measurement module (1200) is a temperature sensor (1210) for measuring temperature;
  • a conversion unit 1220 that converts the measured temperature value into a digital signal;
  • a receiving unit 1230 that receives a digital signal;
  • a transmitter 1240 that transmits a digital signal;
  • a temperature measurement module control unit 1250 for controlling the temperature sensor 1210, conversion unit 1220, receiver 1230, and transmitter 1240,
  • the temperature measurement module control unit 1250 measures the temperature through the temperature sensor 1210 according to the measurement signal received through the receiver 1230, and converts the measured temperature value to the conversion unit 1220. Converting to a temperature value signal through, and providing the converted temperature value signal through the transmitting unit 1240,
  • the temperature measurement module control unit 1250 combines the received measurement signal and the temperature value signal converted from the measured temperature value to form one data sequence, and then converts the one data sequence into the The temperature measurement module 1200 may be provided externally.
  • the digital control unit 1300 has a plurality of communication ports, each communication port indicating the location information of one temperature measurement module 1200, and analyzing the response signal received through each communication port to determine the corresponding location. It may be identifying a temperature value.
  • the plurality of temperature measurement modules 1200 are connected in parallel with the digital control unit 1300, and the temperature measurement module control unit 1250 is connected to the reception unit 1230.
  • the temperature is measured through the temperature sensor 1210, the measured temperature value is converted into a temperature value signal through the converter 1220, and the converted temperature value signal is is provided through the transmitter 1240, and the temperature measurement module control unit 1250 combines the received measurement signal and the temperature value signal converted from the measured temperature value to form one data sequence. After being formed, the single data sequence may be provided to the outside of the temperature measurement module 1200.
  • the digital control unit 1300 has a plurality of communication ports, each communication port representing the location information of one temperature measurement module 1200, and analyzing the response signal received through each communication port to determine the corresponding location. It may be identifying a temperature value.
  • the digital control unit 1300 analyzes the received response signal using a plurality of communication ports connected in parallel, it determines which temperature measurement module 1200 and what temperature it is based on each communication port. It will be easy to determine whether the temperature value is measured by the measurement module 1200.
  • the digital control unit 1300 sets a temperature measurement cycle and monitors the temperature measurement value of the temperature measurement module in real time according to the temperature measurement cycle, and the monitored temperature measurement value exceeds a preset temperature range.
  • the location information of the temperature measurement module and the monitored temperature measurement value may be provided to the outside.
  • the digital control unit 1300 sets a temperature measurement cycle, monitors the temperature measurement value of the temperature measurement module in real time according to the temperature measurement cycle, and changes the rate of change of the monitored temperature measurement value within a preset change rate range. If it exceeds, the location information of the temperature measurement module, the monitored temperature measurement value, and the rate of change may be provided to the outside.
  • the digital control unit 1300 sets a temperature measurement cycle and monitors the temperature measurement value of the temperature measurement module in real time according to the temperature measurement cycle, i) the monitored temperature measurement value is within a preset temperature range. If it exceeds, the location information of the temperature measurement module and the monitored temperature measurement value may be provided to the outside. ii) If the rate of change of the monitored temperature measurement value exceeds the preset change rate range, the The location information of the temperature measurement module, the monitored temperature measurement value, and the rate of change may be provided to the outside.
  • the electrode array may be made of a flexible substrate and may be attached to adapt to the curved surface of the object. That is, since the object may not have a flat surface, the electrode array may be formed of a flexible substrate so that it can be adaptively attached to the surface shape of the object.
  • the digital control unit 1300 transmits digital data received from the temperature measurement module 1200 using power line communication (not shown). It may include more poems). In other words, in order to improve the efficiency of the connection cable, the cable for supplying power can also be used for communication purposes.
  • a generator (not shown) generates an alternating current voltage of 50 to 500 kHz in order to transmit an electric field to the inside of the object through the plurality of electrodes 1100. connect the city). Therefore, the temperature measuring device in the electrode array presented in the present invention can be universally used in other treatment methods other than electric field tumor therapy, in which the skin temperature of the subject must be maintained within a certain temperature by electrically contacting the electrode array with the subject's skin.
  • a temperature measuring device 1000 in an electrode array is attached to the surface of an object and is configured to transmit an electric field to the object.
  • a plurality of electrodes 1100 mounted on and configured to transmit an electric field to the object;
  • a plurality of temperature measurement modules 1200 for measuring the temperature between the plurality of electrodes and the surface of the object;
  • a digital control unit 1300 that connects the plurality of temperature measurement modules 1200 to transmit a digital signal to control each temperature measurement module 1200 and receives a response signal from each temperature measurement module 1200,
  • Each of the temperature measurement modules 1200 includes a temperature sensor 1210 for measuring temperature; A conversion unit 1220 that converts the measured temperature value into a digital signal; A receiving unit 1230 that receives a digital signal; A transmitter 1240 that transmits a digital signal; And a temperature measurement module control unit 1250 for controlling the temperature sensor 1210, conversion unit 1220, receiver 1230, and transmitter 1240.
  • a unique identifier is assigned to the temperature sensor 1210, and the temperature measurement module control unit 1250 measures the temperature through the temperature sensor 1210 according to the measurement signal received through the receiver 1230. , converting the measured temperature value into a temperature value signal through the converter 1220, and providing the converted temperature value signal through the transmitter 1240,
  • the temperature measurement module control unit 1250 combines the unique identifier, the received measurement signal, and the temperature value signal converted from the measured temperature value to form one data sequence, and then The data sequence may be provided to the outside of the temperature measurement module 1200.
  • a unique identifier is assigned to each temperature sensor 1210, and the temperature measurement module control unit 1250 converts the unique identifier, the received measurement signal, and the measured temperature value into a temperature value signal.
  • the one data sequence can be provided to the outside of the temperature measurement module 1200, so when the received one data sequence is analyzed, the unique identifier By using , you will be able to accurately determine which temperature measurement module the temperature value was measured from.
  • the present invention relates to an electrode array for use with a generator (alternating current signal generator) that delivers a therapeutic electric field to a target area of an object.
  • the electrode array includes a plurality of electrode elements configured to be disposed relative to an object. Each electrode element is configured to attach to the skin of a subject.
  • a plurality of temperature sensors sense the temperature of the plurality of electrodes, and the electrode array includes temperature sensors.
  • FIG. 4 is a block diagram of a temperature sensor supporting serial communication for measuring the temperature of each electrode of an electric field therapy electrode array.
  • the temperature sensor 100 has a built-in temperature sensor.
  • the built-in temperature sensor changes voltage depending on the temperature, and this voltage is converted to a digital value through an analog-to-digital converter.
  • the received command and data can be output as is through TX, or the measured temperature value can be added to the received data and output through TX.
  • thermosensor 100 An example of a component suitable for this purpose is the TMP144 from Texas Instrument.
  • the component is programmed with a unique interface address according to the location of the temperature sensor 100 and can individually respond to its own address. Additionally, temperatures can be measured sequentially in response to common commands, allowing the user to read or write to all devices on the bus without having to send individual addresses and commands to each device. Up to 16 temperature sensors can be daisy-chained.
  • FIG. 5 shows an example of transmitting and receiving temperature information by configuring a plurality of temperature sensors 100 in a daisy chain through the host controller 300.
  • the first temperature sensor 100 adds its temperature measurement value 200 to the data part and transmits it through the TX (102) port, and the second temperature sensor adds the command and data received from RX.
  • the temperature sensor adds its temperature measurement to the received data and transmits it via TX. The entire cycle is completed when the data transmitted from the last temperature sensor is received by the host controller.
  • FIG. 6 shows the structure of a host controller 300 for controlling a temperature sensor and sending measured temperature data to a generator or distributor, according to an embodiment.
  • the host controller sends the received temperature measurements to the generator or distributor via UART.
  • FIG. 7 shows the structure of a host controller 400 for controlling a temperature sensor and sending measured temperature data to a generator or distributor, according to an embodiment.
  • the host controller has a structure for power line communication. Temperature measurements obtained sequentially through a plurality of temperature sensors 100 configured in a daisy chain are converted into current through a load in the host controller, and are placed on a power line to transmit temperature information to a generator or distributor.
  • FIG 8 shows the structure of the electrode array 500 having a typical 3X3 electrode structure.
  • An embodiment is shown in which nine temperature sensors 100 for measuring temperature and a host controller 400 connected in series are arranged in an electrode array.
  • the electrode array includes a plurality of electrode 501 elements configured to be disposed relative to an object.
  • Each electrode attached to the subject's skin is connected to a conductor 502, which is a current path, and transmits a treatment electric field to the subject.
  • the host controller 400 transmits the temperature measurement values obtained through serial communication with a plurality of temperature sensors 100 that measure the temperature between the bottom of each electrode and the skin through the connection line 504 and connector 503 connected to the generator or distributor. Or communicate with the generator.
  • the host controller of FIG. 8 may be configured in an electrode array or may be placed on the distributor side.
  • the intensity of the current applied for electric field treatment can be adjusted based on the temperature value of each electrode measured through a plurality of temperature sensors composed of a daisy chain.

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  • Biomedical Technology (AREA)
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Abstract

Un dispositif de mesure de température dans un réseau d'électrodes selon un mode de réalisation de la présente invention est fixé à la surface d'un objet pour transmettre un champ électrique à l'objet. Le dispositif peut comprendre : une pluralité d'électrodes (1100) qui sont montées sur le réseau d'électrodes pour transmettre le champ électrique à l'objet ; une pluralité de modules de mesure de température (1200) pour mesurer la température entre la pluralité d'électrodes (1100) et la surface de l'objet ; et une unité de commande numérique (1300), qui est connectée à la pluralité de modules de mesure de température (1200), transmet des signaux numériques pour commander chacun des modules de mesure de température (1200), et reçoit des signaux de réponse de chacun des modules de mesure de température (1200). Selon un mode de réalisation de la présente invention, le dispositif a pour effet de réduire la complexité d'un circuit et de câbles d'interface pour mesurer la température de chacune des électrodes dans un réseau d'électrodes de thérapie par champ électrique.
PCT/KR2023/013743 2022-10-07 2023-09-13 Dispositif de mesure de température dans un réseau d'électrodes WO2024076029A1 (fr)

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KR1020230115095A KR20240049147A (ko) 2022-10-07 2023-08-31 전극 어레이에서의 온도 측정 장치

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KR20210094579A (ko) * 2018-11-19 2021-07-29 노보큐어 게엠베하 선택적으로 주소 지정 가능한 하위 요소를 하지는 종양 치료장 제공을 위한 어레이
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