WO2024065609A1 - Composition for caring for keratin materials and mask containing the same - Google Patents
Composition for caring for keratin materials and mask containing the same Download PDFInfo
- Publication number
- WO2024065609A1 WO2024065609A1 PCT/CN2022/123076 CN2022123076W WO2024065609A1 WO 2024065609 A1 WO2024065609 A1 WO 2024065609A1 CN 2022123076 W CN2022123076 W CN 2022123076W WO 2024065609 A1 WO2024065609 A1 WO 2024065609A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- acid
- tert
- composition
- butyl
- hydroxy
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 100
- 239000000463 material Substances 0.000 title claims abstract description 27
- 102000011782 Keratins Human genes 0.000 title claims abstract description 25
- 108010076876 Keratins Proteins 0.000 title claims abstract description 25
- 239000002253 acid Substances 0.000 claims abstract description 25
- 239000002738 chelating agent Substances 0.000 claims abstract description 18
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 16
- 239000003002 pH adjusting agent Substances 0.000 claims abstract description 15
- 239000002530 phenolic antioxidant Substances 0.000 claims abstract description 14
- 239000008346 aqueous phase Substances 0.000 claims abstract description 10
- 239000005995 Aluminium silicate Substances 0.000 claims abstract description 8
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229910000323 aluminium silicate Inorganic materials 0.000 claims abstract description 8
- 235000012211 aluminium silicate Nutrition 0.000 claims abstract description 8
- 229910052749 magnesium Inorganic materials 0.000 claims abstract description 8
- 239000011777 magnesium Substances 0.000 claims abstract description 8
- 238000002560 therapeutic procedure Methods 0.000 claims abstract description 5
- 229910052757 nitrogen Inorganic materials 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- -1 ethanoldiglycine acid Chemical class 0.000 claims description 13
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 12
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical group OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 10
- 125000004432 carbon atom Chemical group C* 0.000 claims description 9
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- VKZRWSNIWNFCIQ-WDSKDSINSA-N (2s)-2-[2-[[(1s)-1,2-dicarboxyethyl]amino]ethylamino]butanedioic acid Chemical compound OC(=O)C[C@@H](C(O)=O)NCCN[C@H](C(O)=O)CC(O)=O VKZRWSNIWNFCIQ-WDSKDSINSA-N 0.000 claims description 8
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 8
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical group OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 claims description 8
- 229960001484 edetic acid Drugs 0.000 claims description 8
- 229960003330 pentetic acid Drugs 0.000 claims description 8
- YKTSYUJCYHOUJP-UHFFFAOYSA-N [O--].[Al+3].[Al+3].[O-][Si]([O-])([O-])[O-] Chemical compound [O--].[Al+3].[Al+3].[O-][Si]([O-])([O-])[O-] YKTSYUJCYHOUJP-UHFFFAOYSA-N 0.000 claims description 7
- 229940061720 alpha hydroxy acid Drugs 0.000 claims description 7
- 150000001280 alpha hydroxy acids Chemical class 0.000 claims description 7
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- BGYHLZZASRKEJE-UHFFFAOYSA-N [3-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxy]-2,2-bis[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxymethyl]propyl] 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate Chemical group CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(CCC(=O)OCC(COC(=O)CCC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)(COC(=O)CCC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)COC(=O)CCC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)=C1 BGYHLZZASRKEJE-UHFFFAOYSA-N 0.000 claims description 6
- 125000001931 aliphatic group Chemical group 0.000 claims description 6
- 150000001277 beta hydroxy acids Chemical class 0.000 claims description 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 6
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 6
- 229960004889 salicylic acid Drugs 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- OKOBUGCCXMIKDM-UHFFFAOYSA-N Irganox 1098 Chemical compound CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(CCC(=O)NCCCCCCNC(=O)CCC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)=C1 OKOBUGCCXMIKDM-UHFFFAOYSA-N 0.000 claims description 5
- 150000001261 hydroxy acids Chemical class 0.000 claims description 5
- 239000000758 substrate Substances 0.000 claims description 5
- QEHXDDFROMGLSP-VDBFCSKJSA-K trisodium;(2s)-2-[2-[[(1s)-1-carboxy-2-carboxylatoethyl]amino]ethylamino]butanedioate Chemical compound [Na+].[Na+].[Na+].OC(=O)C[C@@H](C([O-])=O)NCCN[C@H](C([O-])=O)CC([O-])=O QEHXDDFROMGLSP-VDBFCSKJSA-K 0.000 claims description 5
- BVUXDWXKPROUDO-UHFFFAOYSA-N 2,6-di-tert-butyl-4-ethylphenol Chemical compound CCC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 BVUXDWXKPROUDO-UHFFFAOYSA-N 0.000 claims description 4
- PQHYOGIRXOKOEJ-UHFFFAOYSA-N 2-(1,2-dicarboxyethylamino)butanedioic acid Chemical compound OC(=O)CC(C(O)=O)NC(C(O)=O)CC(O)=O PQHYOGIRXOKOEJ-UHFFFAOYSA-N 0.000 claims description 4
- GRUVVLWKPGIYEG-UHFFFAOYSA-N 2-[2-[carboxymethyl-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetic acid Chemical compound C=1C=CC=C(O)C=1CN(CC(=O)O)CCN(CC(O)=O)CC1=CC=CC=C1O GRUVVLWKPGIYEG-UHFFFAOYSA-N 0.000 claims description 4
- CIEZZGWIJBXOTE-UHFFFAOYSA-N 2-[bis(carboxymethyl)amino]propanoic acid Chemical compound OC(=O)C(C)N(CC(O)=O)CC(O)=O CIEZZGWIJBXOTE-UHFFFAOYSA-N 0.000 claims description 4
- ZVVFVKJZNVSANF-UHFFFAOYSA-N 6-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxy]hexyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate Chemical compound CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(CCC(=O)OCCCCCCOC(=O)CCC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)=C1 ZVVFVKJZNVSANF-UHFFFAOYSA-N 0.000 claims description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 4
- 229940120146 EDTMP Drugs 0.000 claims description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 4
- NSOXQYCFHDMMGV-UHFFFAOYSA-N Tetrakis(2-hydroxypropyl)ethylenediamine Chemical compound CC(O)CN(CC(C)O)CCN(CC(C)O)CC(C)O NSOXQYCFHDMMGV-UHFFFAOYSA-N 0.000 claims description 4
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 claims description 4
- 150000001412 amines Chemical class 0.000 claims description 4
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 4
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims description 4
- NFDRPXJGHKJRLJ-UHFFFAOYSA-N edtmp Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CCN(CP(O)(O)=O)CP(O)(O)=O NFDRPXJGHKJRLJ-UHFFFAOYSA-N 0.000 claims description 4
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 4
- 229940061605 tetrasodium glutamate diacetate Drugs 0.000 claims description 4
- UZVUJVFQFNHRSY-OUTKXMMCSA-J tetrasodium;(2s)-2-[bis(carboxylatomethyl)amino]pentanedioate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CC[C@@H](C([O-])=O)N(CC([O-])=O)CC([O-])=O UZVUJVFQFNHRSY-OUTKXMMCSA-J 0.000 claims description 4
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims description 4
- 229940048081 trisodium ethylenediamine disuccinate Drugs 0.000 claims description 4
- 229960000281 trometamol Drugs 0.000 claims description 4
- QBYIENPQHBMVBV-HFEGYEGKSA-N (2R)-2-hydroxy-2-phenylacetic acid Chemical compound O[C@@H](C(O)=O)c1ccccc1.O[C@@H](C(O)=O)c1ccccc1 QBYIENPQHBMVBV-HFEGYEGKSA-N 0.000 claims description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 3
- IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 claims description 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
- 125000000524 functional group Chemical group 0.000 claims description 3
- 239000004310 lactic acid Substances 0.000 claims description 3
- 235000014655 lactic acid Nutrition 0.000 claims description 3
- 229960002510 mandelic acid Drugs 0.000 claims description 3
- 239000001509 sodium citrate Substances 0.000 claims description 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 3
- 235000011083 sodium citrates Nutrition 0.000 claims description 3
- 239000011975 tartaric acid Substances 0.000 claims description 3
- 235000002906 tartaric acid Nutrition 0.000 claims description 3
- KJYSXRBJOSZLEL-UHFFFAOYSA-N (2,4-ditert-butylphenyl) 3,5-ditert-butyl-4-hydroxybenzoate Chemical compound CC(C)(C)C1=CC(C(C)(C)C)=CC=C1OC(=O)C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 KJYSXRBJOSZLEL-UHFFFAOYSA-N 0.000 claims description 2
- CCVYRRGZDBSHFU-UHFFFAOYSA-N (2-hydroxyphenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC=C1O CCVYRRGZDBSHFU-UHFFFAOYSA-N 0.000 claims description 2
- XYXJKPCGSGVSBO-UHFFFAOYSA-N 1,3,5-tris[(4-tert-butyl-3-hydroxy-2,6-dimethylphenyl)methyl]-1,3,5-triazinane-2,4,6-trione Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C)=C1CN1C(=O)N(CC=2C(=C(O)C(=CC=2C)C(C)(C)C)C)C(=O)N(CC=2C(=C(O)C(=CC=2C)C(C)(C)C)C)C1=O XYXJKPCGSGVSBO-UHFFFAOYSA-N 0.000 claims description 2
- KGRVJHAUYBGFFP-UHFFFAOYSA-N 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) Chemical compound CC(C)(C)C1=CC(C)=CC(CC=2C(=C(C=C(C)C=2)C(C)(C)C)O)=C1O KGRVJHAUYBGFFP-UHFFFAOYSA-N 0.000 claims description 2
- SFJOBYZKUSLNIG-UHFFFAOYSA-N 2,3,4-tris(1-phenylethyl)phenol Chemical compound C=1C=C(O)C(C(C)C=2C=CC=CC=2)=C(C(C)C=2C=CC=CC=2)C=1C(C)C1=CC=CC=C1 SFJOBYZKUSLNIG-UHFFFAOYSA-N 0.000 claims description 2
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 claims description 2
- CZNRFEXEPBITDS-UHFFFAOYSA-N 2,5-bis(2-methylbutan-2-yl)benzene-1,4-diol Chemical compound CCC(C)(C)C1=CC(O)=C(C(C)(C)CC)C=C1O CZNRFEXEPBITDS-UHFFFAOYSA-N 0.000 claims description 2
- JZODKRWQWUWGCD-UHFFFAOYSA-N 2,5-di-tert-butylbenzene-1,4-diol Chemical compound CC(C)(C)C1=CC(O)=C(C(C)(C)C)C=C1O JZODKRWQWUWGCD-UHFFFAOYSA-N 0.000 claims description 2
- HWQVXNFIYABVIW-UHFFFAOYSA-N 2-(carboxymethylamino)-4,5-dihydroxypentanoic acid Chemical compound OCC(O)CC(C(O)=O)NCC(O)=O HWQVXNFIYABVIW-UHFFFAOYSA-N 0.000 claims description 2
- QSRJVOOOWGXUDY-UHFFFAOYSA-N 2-[2-[2-[3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propanoyloxy]ethoxy]ethoxy]ethyl 3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propanoate Chemical compound CC(C)(C)C1=C(O)C(C)=CC(CCC(=O)OCCOCCOCCOC(=O)CCC=2C=C(C(O)=C(C)C=2)C(C)(C)C)=C1 QSRJVOOOWGXUDY-UHFFFAOYSA-N 0.000 claims description 2
- VFBJXXJYHWLXRM-UHFFFAOYSA-N 2-[2-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxy]ethylsulfanyl]ethyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate Chemical compound CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(CCC(=O)OCCSCCOC(=O)CCC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)=C1 VFBJXXJYHWLXRM-UHFFFAOYSA-N 0.000 claims description 2
- GAODDBNJCKQQDY-UHFFFAOYSA-N 2-methyl-4,6-bis(octylsulfanylmethyl)phenol Chemical compound CCCCCCCCSCC1=CC(C)=C(O)C(CSCCCCCCCC)=C1 GAODDBNJCKQQDY-UHFFFAOYSA-N 0.000 claims description 2
- HXIQYSLFEXIOAV-UHFFFAOYSA-N 2-tert-butyl-4-(5-tert-butyl-4-hydroxy-2-methylphenyl)sulfanyl-5-methylphenol Chemical compound CC1=CC(O)=C(C(C)(C)C)C=C1SC1=CC(C(C)(C)C)=C(O)C=C1C HXIQYSLFEXIOAV-UHFFFAOYSA-N 0.000 claims description 2
- PFANXOISJYKQRP-UHFFFAOYSA-N 2-tert-butyl-4-[1-(5-tert-butyl-4-hydroxy-2-methylphenyl)butyl]-5-methylphenol Chemical compound C=1C(C(C)(C)C)=C(O)C=C(C)C=1C(CCC)C1=CC(C(C)(C)C)=C(O)C=C1C PFANXOISJYKQRP-UHFFFAOYSA-N 0.000 claims description 2
- GPNYZBKIGXGYNU-UHFFFAOYSA-N 2-tert-butyl-6-[(3-tert-butyl-5-ethyl-2-hydroxyphenyl)methyl]-4-ethylphenol Chemical compound CC(C)(C)C1=CC(CC)=CC(CC=2C(=C(C=C(CC)C=2)C(C)(C)C)O)=C1O GPNYZBKIGXGYNU-UHFFFAOYSA-N 0.000 claims description 2
- QRLSTWVLSWCGBT-UHFFFAOYSA-N 4-((4,6-bis(octylthio)-1,3,5-triazin-2-yl)amino)-2,6-di-tert-butylphenol Chemical compound CCCCCCCCSC1=NC(SCCCCCCCC)=NC(NC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)=N1 QRLSTWVLSWCGBT-UHFFFAOYSA-N 0.000 claims description 2
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims description 2
- PRWJPWSKLXYEPD-UHFFFAOYSA-N 4-[4,4-bis(5-tert-butyl-4-hydroxy-2-methylphenyl)butan-2-yl]-2-tert-butyl-5-methylphenol Chemical compound C=1C(C(C)(C)C)=C(O)C=C(C)C=1C(C)CC(C=1C(=CC(O)=C(C=1)C(C)(C)C)C)C1=CC(C(C)(C)C)=C(O)C=C1C PRWJPWSKLXYEPD-UHFFFAOYSA-N 0.000 claims description 2
- VSAWBBYYMBQKIK-UHFFFAOYSA-N 4-[[3,5-bis[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2,4,6-trimethylphenyl]methyl]-2,6-ditert-butylphenol Chemical compound CC1=C(CC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)C(C)=C(CC=2C=C(C(O)=C(C=2)C(C)(C)C)C(C)(C)C)C(C)=C1CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 VSAWBBYYMBQKIK-UHFFFAOYSA-N 0.000 claims description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims description 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 2
- NMMKNHWQYKOEJV-UHFFFAOYSA-L C(C)(=O)[O-].[Na+].C(CC(O)(C(=O)O)CC(=O)O)(=O)[O-].[K+] Chemical compound C(C)(=O)[O-].[Na+].C(CC(O)(C(=O)O)CC(=O)O)(=O)[O-].[K+] NMMKNHWQYKOEJV-UHFFFAOYSA-L 0.000 claims description 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 claims description 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 2
- 239000007983 Tris buffer Substances 0.000 claims description 2
- STLLXWLDRUVCHL-UHFFFAOYSA-N [2-[1-[2-hydroxy-3,5-bis(2-methylbutan-2-yl)phenyl]ethyl]-4,6-bis(2-methylbutan-2-yl)phenyl] prop-2-enoate Chemical compound CCC(C)(C)C1=CC(C(C)(C)CC)=CC(C(C)C=2C(=C(C=C(C=2)C(C)(C)CC)C(C)(C)CC)OC(=O)C=C)=C1O STLLXWLDRUVCHL-UHFFFAOYSA-N 0.000 claims description 2
- CGRTZESQZZGAAU-UHFFFAOYSA-N [2-[3-[1-[3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propanoyloxy]-2-methylpropan-2-yl]-2,4,8,10-tetraoxaspiro[5.5]undecan-9-yl]-2-methylpropyl] 3-(3-tert-butyl-4-hydroxy-5-methylphenyl)propanoate Chemical compound CC(C)(C)C1=C(O)C(C)=CC(CCC(=O)OCC(C)(C)C2OCC3(CO2)COC(OC3)C(C)(C)COC(=O)CCC=2C=C(C(O)=C(C)C=2)C(C)(C)C)=C1 CGRTZESQZZGAAU-UHFFFAOYSA-N 0.000 claims description 2
- IORUEKDKNHHQAL-UHFFFAOYSA-N [2-tert-butyl-6-[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenyl] prop-2-enoate Chemical compound CC(C)(C)C1=CC(C)=CC(CC=2C(=C(C=C(C)C=2)C(C)(C)C)OC(=O)C=C)=C1O IORUEKDKNHHQAL-UHFFFAOYSA-N 0.000 claims description 2
- 239000000908 ammonium hydroxide Substances 0.000 claims description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 claims description 2
- 235000003704 aspartic acid Nutrition 0.000 claims description 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 claims description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 2
- 235000010216 calcium carbonate Nutrition 0.000 claims description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 2
- 125000004122 cyclic group Chemical group 0.000 claims description 2
- 150000002148 esters Chemical group 0.000 claims description 2
- 125000005843 halogen group Chemical group 0.000 claims description 2
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 claims description 2
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 2
- 239000001095 magnesium carbonate Substances 0.000 claims description 2
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 2
- 235000014380 magnesium carbonate Nutrition 0.000 claims description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims description 2
- 235000019796 monopotassium phosphate Nutrition 0.000 claims description 2
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- 239000012209 synthetic fiber Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Definitions
- the present invention relates to a composition for caring for keratin materials and a mask containing the same.
- the present invention also relates to a non-therapeutic process for caring for keratin materials.
- a mask which is formed by a tissue such as a non-woven fabric sheet impregnated with a lotion or the like has been used for cosmetic treatments of the skin, in particular the face.
- Masks are popular with many consumers since they can put the masks on the face for a period of time and then take away the masks, without massaging on the face during the application.
- Some clay mask formulation comprises hydroxyl acid and niacinamide for anti-acne/oil control and anti-imperfection.
- Hydroxyl acid results in a formulation with a lower pH, meanwhile renders the formulation unstable as water will come out on surface and color will change.
- the lotion therein comprising a hydroxyl acid is stable.
- an object of the present invention is to provide a clay mask for caring for the skin, the lotion therein comprising a hydroxyl acid is stable.
- the present invention provides a composition comprising in an aqueous phase:
- “stable” means the composition has obvious change on pH, appearance, and viscosity for at least two months.
- composition according to the present invention can be used to care for the skin.
- the present invention provides a mask for caring for keratin materials, comprising:
- composition according to the present invention impregnated into the mask tissue.
- the present invention provides a non-therapeutic process for caring for keratin materials, comprising the steps of:
- keratin materials means the entire skin of the body, excluding the scalp and mucous membranes.
- the term “keratin materials” preferably concerns the skin of the face, in particular the skin of the forehead and/or of the sides of the nose and/or of the chin.
- the present invention provides a composition comprises in an aqueous phase:
- the composition according to the present invention comprises magnesium aluminium silicate.
- Magnesium aluminium silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group, class number thereof is 1327-43-1 and the molecular formula thereof is MgAl [Al (SiO 4 ) 2 ] .
- magnesium aluminum silicate is present in an amount ranging from 0.1 wt. %to 10 wt. %, preferably from 0.5 wt. %to 6 wt. %, more preferably from 1 wt. %to 4 wt. %, relative to the total weight of the composition.
- the composition according to the present invention comprises at least one hydroxyl acid.
- Hydroxy acid is selected from alpha hydroxy acid and beta hydroxy acid, and combinations thereof.
- alpha-hydroxy acid is understood to mean, according to the present invention, acarboxylic acid having at least one hydroxyl functional group occupying an alpha-position on said acid (carbon adjacent to a carboxylic acid functional group) .
- Suitable alpha hydroxy acids includes glycolic acid, citric acid, lactic acid, methyllactic acid, glucuronic acid, pyruvic acid, 2-hydroxybutanoic acid, 2-hydroxypentanoic acid, 2-hydroxyhexanoic acid, 2-hydroxyheptanoic acid, 2-hydroxyoctanoic acid, 2-hydroxynonanoic acid, 2-hydroxydecanoic acid, 2-hydroxyundecanoic acid, 2-hydroxydodecanoic acid, 2-hydroxytetradecanoic acid, 2-hydroxyhexadecanoic acid, 2-hydroxyoctadecanoic acid, 2-hydroxytetracosanoic acid, 2-hydroxyeicosanoic acid, mandelic acid, phenyllactic acid, gluconic acid, galacturonic acid, aleuritic acid, ribonic acid, tartronic acid, tartaric acid, malic acid, fumaric acid.
- the alpha hydroxy acid is selected from lactic acid, glycolic acid, tartaric acid, mandelic acid, citric acid, and combinations thereof.
- beta-hydroxy acid is understood to mean, according to the present invention, acarboxylic acid having a hydroxyl functional group and a carboxylic functional group separated by two carbon atoms.
- the beta hydroxy acid is selected from salicylic acid and its derivatives of formula (I) :
- R is a linear, branched or cyclic saturated aliphatic group or an aliphatic unsaturated group containing one or a number of double bonds, which may or may not be conjugated, these groups containing from 2 to 22, preferably 3 to 11 carbon atoms and being able to be substituted for example by at least one substituent selected from (a) halogen atoms, (b) the trifluoromethyl group, (c) hydroxyl groups in the free form or esterified by an acid having from 1 to 6 carbon atoms or (d) a carboxyl functional group which is free or esterified by a lower alcohol having from 1 to 6 carbon atoms;
- R' is a hydroxyl group or an ester functional group of formula (II) :
- R 1 is a linear or branched saturated or unsaturated aliphatic group having from 1 to 18 carbon atoms.
- Preferred salicylic acid derivatives include 5-n-octanoyl salicylic acid (capryloyl salicylic acid) , 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyloxy salicylic acid and 4-n-heptyloxy salicylic acid.
- the composition according to the present invention comprises a compound selected from salicylic acid, 5-n-octanoyl salicylic acid, 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyloxy salicylic acid, 4-n-heptyloxy salicylic acid, and a combination thereof.
- composition according to the present invention comprises salicylic acid.
- Hydroxy acid is contained to provide enhanced penetration of the composition into the skin.
- the hydroxyl acid is present in an amount ranging from 0.1 wt. %to 3 wt. %, preferably from 0.2 wt. %to 2 wt. %, and more preferably from 0.3 wt. %to 1.5 wt. %, relative to the total weight of the composition.
- the composition according to the present invention comprises at least one pH adjusting agent.
- the pH adjusting agent is selected from triethanolamine (TEA) , amine base tromethamine, tetrahydroxypropyl ethylenediamine, diethanolamine, aminomethyl propanol, sodium hydroxide, potassium hydroxide, ammonium hydroxide, sodium phosphate, sodium gluconate, sodium lactate, sodium citrate, sodium acetate potassium citrate, sodium bicarbonate, potassium bicarbonate, sodium dihydrogen phosphate, potassium dihydrogen phosphate, sodium carbonate, sodium hydrogen carbonate, magnesium carbonate, calcium carbonate, and a combination thereof.
- TAA triethanolamine
- the pH adjusting agent is selected from triethanolamine (TEA) , amine base tromethamine, tetrahydroxypropyl ethylenediamine, diethanolamine, aminomethyl propanol, and a combination thereof.
- TAA triethanolamine
- amine base tromethamine tetrahydroxypropyl ethylenediamine
- diethanolamine aminomethyl propanol
- the pH adjusting agent is triethanolamine.
- the skilled in the art can adjust the amount of the pH adjust agent so that the composition has a pH of 4-8, preferably 5-8, more preferably 5-6.
- the composition according to the present invention comprises at least one chelating agent.
- the chelating agent is selected from aminocarboxylic acids and salts thereof.
- the salts are especially alkali metal, alkaline-earth metal, ammonium and substituted ammonium salts.
- the chelating agents may be selected in particular from the compounds having the following INCI name:
- DTPA diethylenetriaminepentaacetic acid
- ethylenediaminedisuccinic acid EDDS
- trisodium ethylenediamine disuccinate such as Octaquest E30 from INNOSPEC ACTIVE CHEMICALS
- EDTA ethylenediaminetetraacetic acid
- EDDG ethylenediamine-N, N'-diglutaric acid
- HPDDS 2-hydroxypropylenediamine-N, N'-disuccinic acid
- EDDHA ethylenediamine-N, N'-bis (ortho-hydroxyphenylacetic acid)
- NTA nitrilotriacetic acid
- MGDA methylglycine diacetic acid
- beta-alanine-N, N'-diacetic acid, aspartic acid-N, N'-diacetic acid and aspartic acid-N-monoacetic acid (described in EP-A-509382) ,
- IDSSA iminodisuccinic acid
- GLDA tetrasodium glutamate diacetate
- EDTA ethylenediamine-tetraacetic acid
- DTPA diethylenetriaminepentaacetic acid
- S S'-ethylenediaminedisuccinic acid
- EDDS trisodium ethylenediamine disuccinate
- ETMP ethylenediaminetetramethylenephosphonic acid
- GLDA tetrasodium glutamate diacetate
- the composition according to the present invention is stable. It can remain stable for at least two months at various temperatures for example, 4°C, at room temperature (25°C) , 37°C, 45°C and 55°C.
- the chelating agent is present in an amount ranging from 0.05 wt. %to 5 wt. %, preferably from 0.1 wt. %to 1 wt. %, and more preferably from 0.15 wt. %to 0.6 wt. %, relative to the total weight of the composition.
- the composition according to the present invention comprises at least one phenolic antioxidant.
- phenolic antioxidants mention may be made of, those which have a hindered phenol structure or a semi-hindered phenol structure within the molecule.
- the phenolic antioxidant is selected from pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, N, N’ -hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , and a mixture thereof.
- composition according to the present invention can remain the color unchanged at different temperatures from 4°C to 45°Cfor long time, for example, at least 2 months.
- the phenolic antioxidant is present in amount ranging from0.01 wt. %to 1 wt. %, preferably from 0.03 wt. %to 0.5 wt. %, more preferably from 0.05 wt. %to 0.2 wt. %, relative to the total weight of the composition.
- composition of the present invention comprises an aqueous phase.
- the aqueous phase of the composition according to the present invention comprises water and optionally one or more water-miscible or at least partially water-miscible solvents, for instance C2 to C8 polyols or monoalcohols, such as ethanol and isopropanol.
- water-miscible or at least partially water-miscible solvents for instance C2 to C8 polyols or monoalcohols, such as ethanol and isopropanol.
- polyol should be understood as meaning any organic molecule comprising at least two free hydroxyl groups.
- examples of polyols that may be mentioned include glycerin, and glycols, for instance butylene glycol, propanediol, propylene glycol, dipropylene glycol, pentylene glycol, and isoprene glycol, caprylyl glycol.
- the at least one C2-C8 polyol is selected from propanediol, pentylene glycol, dipropylene glycol, glycerin, and a combination thereof.
- the aqueous phase may represent in an amount ranging from 30 wt. %to 97.5 wt. %, preferably from 30 wt. %to 97 wt. %, more preferably from 60 wt. %to 97 wt. %, relative to the total weight of the composition.
- composition according to the present invention comprises no oily phase.
- composition according to the present invention can comprises one or more additional cosmetic active ingredients.
- composition of the present invention may comprise one or more conventional cosmetic adjuvants or additives, for instance, fragrances, surfactants, preserving agents (for example, chlorphenesin and phenoxyethanol) and bactericides (for example, hydroxyacetophenone) , thickeners (for example, xanthan gum, Hydroxyethylcellulose) , and mixtures thereof.
- fragrances for instance, fragrances, surfactants, preserving agents (for example, chlorphenesin and phenoxyethanol) and bactericides (for example, hydroxyacetophenone) , thickeners (for example, xanthan gum, Hydroxyethylcellulose) , and mixtures thereof.
- preserving agents for example, chlorphenesin and phenoxyethanol
- bactericides for example, hydroxyacetophenone
- thickeners for example, xanthan gum, Hydroxyethylcellulose
- the present invention provides a composition for caring for keratin materials comprising in an aqueous phase, relative to the total weight of the composition:
- a phenolic antioxidant selected from pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, N, N’ -hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , and a mixture thereof.
- composition according to the present invention can be impregnated into a water insoluble mask tissue to form a mask.
- the present invention relates to a mask for caring for keratin materials, comprising:
- composition according to the present invention impregnated into the mask tissue.
- the mask according to the present invention comprises a water insoluble mask tissue.
- water insoluble means that the mask tissue is not dissolvable in water and it doesn’ t break apart upon immersion in water.
- the skilled in the art can choose a suitable mask tissue and the weight ratio of the mask tissue used and the composition according to the present invention based on the nature of the composition.
- the mask tissue can be a woven or non-woven fabric made of natural fibers such as cotton, pulp, bamboo and cellulose fibers, semi-natural fibers such as viscose rayon fibers and synthetic fibers such as polyester fibers, polyethylene terephthalate fibers, polyethylene fibers, and polypropylene fibers. Two or more selected from the above fibers may be used in combination.
- the mask tissue is an alginate tissue.
- Alginate tissues are known in the art and are described in WO2020001069A1.
- an alginate tissue may comprise a water insoluble alginate chosen from calcium alginate, strontium alginate, zinc alginate, copper alginate, manganese alginate, or a mixture thereof, preferably calcium alginate, preferably in an amount ranging from 20 wt. %to 100 wt. %, preferably from 20 wt. %to 50 wt. %, relative to the total weight of the tissue.
- the composition according to the present invention comprises a pH adjusting agent selected from sodium acetate, sodium citrate, sodium tartrate, and a combination thereof in an amount ranging from 0.01 wt. %to 1.0 wt. %, preferably from 0.05 wt. %to 0.45 wt. %, more preferably from 0.15 wt. %to 0.3 wt. %, relative to the total weight of the composition according to the present invention.
- a pH adjusting agent selected from sodium acetate, sodium citrate, sodium tartrate, and a combination thereof in an amount ranging from 0.01 wt. %to 1.0 wt. %, preferably from 0.05 wt. %to 0.45 wt. %, more preferably from 0.15 wt. %to 0.3 wt. %, relative to the total weight of the composition according to the present invention.
- the mask tissue may be consisted of one or more layers. If a multilayer tissue is used, the material of each layer may be the same or different from each other.
- the multilayer tissue can be prepared by laminating multiple layers made from the materials mentioned above.
- the mask tissue can have a wide variety of shapes, depending on the desired use and characteristic of the mask.
- the mask tissue is typically designed to fit the area of the skin to which topical application is desired.
- the mask tissue is designed to correspond to the shape of the face avoiding the eye, nostril, and mouth areas, as necessary.
- the weight ratio of the water insoluble substrate and the composition ranges from 1: 3 to 1: 20. More preferably, the weight ratio of the water insoluble substrate and the composition ranges from 1: 10 to 1: 18.
- the mask according to the present invention can be used as a skin mask and is intended for topical application and for skin care.
- the present invention provides a non-therapeutic process for caring for keratin materials, comprising the steps of:
- composition or the mask as defined above are applied on at least one zone of the skin.
- composition or the mask as defined above are applied on facial skin and/or eye skin.
- the application time is from 5 minutes to 45 minutes, preferably from 10 minutes to 30 minutes.
- Tissue used made of 100%copper ammonia fibre, with a thickness of 0.3mm, available under the tradename SE384 from the company Asahi-Kasei.
- compositions of comparative examples (CE. ) 1-3 and invention examples (IE. ) 1-3 were prepared according to the amounts given in Table 2. The amount of each component is given in%by weight of the total weight of the composition.
- compositions listed above were prepared by mixing all ingredients and stirring them to obtain a homogenous mixture.
- Masks were prepared by impregnating a tissue with the above compositions, respectively, wherein the weight ratio of the substrate used and the composition is 1: 17.
- compositions obtained above were evaluated in terms of viscosity, pH, and appearance at 4°C, room temperature (25°C) , 37°C, 45°C, and 55°C as follows.
- the viscosity of a composition was measured at 25°C upon preparation, and after being remained at 25°C or 45°C for a certain period of time, using a Rheomat 100 Plus viscometer equipped with a spindle M2, the measurement being performed after 10 minutes of rotation of the spindle in a composition (after which time stabilization of the viscosity and of the spin speed of the spindle are observed) , at a shear rate of 200 rpm.
- the pH value of a composition was measured at 25°C upon preparation, and after being remained at 25°C or 45°C for a certain period of time.
- the samples’ appearance was observed when its temperature achieved the indicated temperature (T0) , 1 month after its temperature achieved the indicated temperature (T1M) , and 2 months after its temperature achieved the indicated temperature (T2M) .
- the appearance will be evaluated as conform if its appearance does not change as compared with its appearance at T0.
- compositions according to the present invention did not change substantially after being remained at 4°C, 25°C, 37°C, 45°C, and/or 55°C for a certain period of time, thus composition according to the present invention are stable.
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- Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
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Abstract
A composition for caring for keratin materials comprises in an aqueous phase: i) magnesium aluminium silicate; ii) at least one hydroxyl acid; ii) at least one pH adjusting agent; iv) at least one chelating agent; and v) at least one phenolic antioxidant. A mask comprises the composition. A non-therapeutic process for caring for keratin materials comprises the step of applying the composition or the mask on the keratin materials.
Description
The present invention relates to a composition for caring for keratin materials and a mask containing the same. The present invention also relates to a non-therapeutic process for caring for keratin materials.
BACKGROUND ART
A mask which is formed by a tissue such as a non-woven fabric sheet impregnated with a lotion or the like has been used for cosmetic treatments of the skin, in particular the face.
Masks are popular with many consumers since they can put the masks on the face for a period of time and then take away the masks, without massaging on the face during the application.
It is also known to use active ingredients in the cosmetic products for caring for the skin, such as cleaning, hydration, pore minimizing, and so on.
Some clay mask formulation comprises hydroxyl acid and niacinamide for anti-acne/oil control and anti-imperfection. Hydroxyl acid results in a formulation with a lower pH, meanwhile renders the formulation unstable as water will come out on surface and color will change.
Thus, there is a need for a clay mask for caring for the skin, the lotion therein comprising a hydroxyl acid is stable.
SUMMARY OF THE INVENTION
Thus, an object of the present invention is to provide a clay mask for caring for the skin, the lotion therein comprising a hydroxyl acid is stable.
Thus, according to a first aspect, the present invention provides a composition comprising in an aqueous phase:
i) magnesium aluminium silicate;
ii) at least one hydroxyl acid;
iii) at least one pH adjusting agent;
iv) at least one chelating agent; and
v) at least one phenolic antioxidant.
It was found that the composition is stable over time.
In the present application, “stable” means the composition has obvious change on pH, appearance, and viscosity for at least two months.
The composition according to the present invention can be used to care for the skin.
According to a second aspect, the present invention provides a mask for caring for keratin materials, comprising:
A) a water insoluble mask tissue, and
B) the composition according to the present invention impregnated into the mask tissue.
According to a third aspect, the present invention provides a non-therapeutic process for caring for keratin materials, comprising the steps of:
(i) applying the composition or the mask according to the present invention on the keratin materials;
(ii) allowing the composition or the mask to remain on the keratin materials for a period of time; and
(iii) removing the composition or the mask from the keratin materials.
Other aspects and advantages of the present invention will emerge more clearly on reading the description and the examples that follow.
Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art the present invention belongs to. When the definition of a term in the present description conflicts with the meaning as commonly understood by those skilled in the art the present invention belongs to, the definition described herein shall apply.
In that which follows and unless otherwise indicated, the limits of a range of values are included within this range, in particular in the expressions "between... and…" and "from... to... " .
Moreover, the expression "at least one" used in the present description is equivalent to the expression "one or more" .
Throughout the instant application, the term “comprising” is to be interpreted as encompassing all specifically mentioned features as well as optional, additional, unspecified ones. As used herein, the use of the term “comprising” also discloses the embodiment wherein no features other than the specifically mentioned features are present (i.e. “consisting of” ) .
Unless otherwise specified, all numerical values expressing amount of ingredients and the like which are used in the description and claims are to be understood as being modified by the term “about” . Accordingly, unless indicated to the contrary, the numerical values and parameters described herein are approximate values, which are capable of being changed according to the desired purpose as required.
All percentages in the present invention refer to weight percentage, unless otherwise specified.
Within the context of the present invention, the term "keratin materials" means the entire skin of the body, excluding the scalp and mucous membranes. The term "keratin materials" preferably concerns the skin of the face, in particular the skin of the forehead and/or of the sides of the nose and/or of the chin.
According to the first aspect, the present invention provides a composition comprises in an aqueous phase:
i) magnesium aluminium silicate;
ii) at least one hydroxyl acid;
iii) at least one pH adjusting agent;
iv) at least one chelating agent; and
v) at least one phenolic antioxidant.
Magnesium aluminum silicate
According to the first aspect, the composition according to the present invention comprises magnesium aluminium silicate.
Magnesium aluminium silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group, class number thereof is 1327-43-1 and the molecular formula thereof is MgAl [Al (SiO
4)
2] .
As a commercial product of magnesium aluminum silicate, mention can be made of that available under the name VEEGUM R from the company VANDERBILT.
Advantageously, magnesium aluminum silicate is present in an amount ranging from 0.1 wt. %to 10 wt. %, preferably from 0.5 wt. %to 6 wt. %, more preferably from 1 wt. %to 4 wt. %, relative to the total weight of the composition.
Hydroxy acids
According to the first aspect, the composition according to the present invention comprises at least one hydroxyl acid.
Hydroxy acid is selected from alpha hydroxy acid and beta hydroxy acid, and combinations thereof.
Alpha hydroxy acids
The term “alpha-hydroxy acid” is understood to mean, according to the present invention, acarboxylic acid having at least one hydroxyl functional group occupying an alpha-position on said acid (carbon adjacent to a carboxylic acid functional group) .
Suitable alpha hydroxy acids includes glycolic acid, citric acid, lactic acid, methyllactic acid, glucuronic acid, pyruvic acid, 2-hydroxybutanoic acid, 2-hydroxypentanoic acid, 2-hydroxyhexanoic acid, 2-hydroxyheptanoic acid, 2-hydroxyoctanoic acid, 2-hydroxynonanoic acid, 2-hydroxydecanoic acid, 2-hydroxyundecanoic acid, 2-hydroxydodecanoic acid, 2-hydroxytetradecanoic acid, 2-hydroxyhexadecanoic acid, 2-hydroxyoctadecanoic acid, 2-hydroxytetracosanoic acid, 2-hydroxyeicosanoic acid, mandelic acid, phenyllactic acid, gluconic acid, galacturonic acid, aleuritic acid, ribonic acid, tartronic acid, tartaric acid, malic acid, fumaric acid.
Preferably, the alpha hydroxy acid is selected from lactic acid, glycolic acid, tartaric acid, mandelic acid, citric acid, and combinations thereof.
Beta hydroxy acids
The term “beta-hydroxy acid” is understood to mean, according to the present invention, acarboxylic acid having a hydroxyl functional group and a carboxylic functional group separated by two carbon atoms.
Preferably, the beta hydroxy acid is selected from salicylic acid and its derivatives of formula (I) :
wherein R is a linear, branched or cyclic saturated aliphatic group or an aliphatic unsaturated group containing one or a number of double bonds, which may or may not be conjugated, these groups containing from 2 to 22, preferably 3 to 11 carbon atoms and being able to be substituted for example by at least one substituent selected from (a) halogen atoms, (b) the trifluoromethyl group, (c) hydroxyl groups in the free form or esterified by an acid having from 1 to 6 carbon atoms or (d) a carboxyl functional group which is free or esterified by a lower alcohol having from 1 to 6 carbon atoms;
R' is a hydroxyl group or an ester functional group of formula (II) :
wherein R
1 is a linear or branched saturated or unsaturated aliphatic group having from 1 to 18 carbon atoms.
Preferred salicylic acid derivatives include 5-n-octanoyl salicylic acid (capryloyl salicylic acid) , 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyloxy salicylic acid and 4-n-heptyloxy salicylic acid.
Preferably, the composition according to the present invention comprises a compound selected from salicylic acid, 5-n-octanoyl salicylic acid, 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyloxy salicylic acid, 4-n-heptyloxy salicylic acid, and a combination thereof.
More preferably, the composition according to the present invention comprises salicylic acid.
Hydroxy acid is contained to provide enhanced penetration of the composition into the skin.
Advantageously, the hydroxyl acid is present in an amount ranging from 0.1 wt. %to 3 wt. %, preferably from 0.2 wt. %to 2 wt. %, and more preferably from 0.3 wt. %to 1.5 wt. %, relative to the total weight of the composition.
pH adjusting agents
According to the first aspect, the composition according to the present invention comprises at least one pH adjusting agent.
For the purpose of the present invention, the pH adjusting agent is selected from triethanolamine (TEA) , amine base tromethamine, tetrahydroxypropyl ethylenediamine, diethanolamine, aminomethyl propanol, sodium hydroxide, potassium hydroxide, ammonium hydroxide, sodium phosphate, sodium gluconate, sodium lactate, sodium citrate, sodium acetate potassium citrate, sodium bicarbonate, potassium bicarbonate, sodium dihydrogen phosphate, potassium dihydrogen phosphate, sodium carbonate, sodium hydrogen carbonate, magnesium carbonate, calcium carbonate, and a combination thereof.
Preferably, the pH adjusting agent is selected from triethanolamine (TEA) , amine base tromethamine, tetrahydroxypropyl ethylenediamine, diethanolamine, aminomethyl propanol, and a combination thereof.
Most preferably, the pH adjusting agent is triethanolamine.
The skilled in the art can adjust the amount of the pH adjust agent so that the composition has a pH of 4-8, preferably 5-8, more preferably 5-6.
Chelating agent
According to the first aspect, the composition according to the present invention comprises at least one chelating agent.
Preferably, the chelating agent is selected from aminocarboxylic acids and salts thereof.
The salts are especially alkali metal, alkaline-earth metal, ammonium and substituted ammonium salts.
The chelating agents may be selected in particular from the compounds having the following INCI name:
diethylenetriaminepentaacetic acid (DTPA) ,
ethylenediaminedisuccinic acid (EDDS) and trisodium ethylenediamine disuccinate such as Octaquest E30 from INNOSPEC ACTIVE CHEMICALS,
ethylenediaminetetraacetic acid (EDTA) ,
ethylenediamine-N, N'-diglutaric acid (EDDG) ,
glycinamide-N, N'-disuccinic acid (GADS) ,
2-hydroxypropylenediamine-N, N'-disuccinic acid (HPDDS) ,
ethylenediamine-N, N'-bis (ortho-hydroxyphenylacetic acid) (EDDHA) ,
N, N'-bis (2-hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) ,
nitrilotriacetic acid (NTA) ,
methylglycine diacetic acid (MGDA) ,
N-2-hydroxyethyl-N, N-diacetic acid and glyceryl imino diacetic acid (as described in documents EP-A-317542 and EP-A-399133) ,
iminodiacetic acid-N-2-hydroxypropyl sulfonic acid and aspartic acid N-carboxymethyl N-2-hydroxypropyl-3-sulfonic acid (as described in EP-A-516102) ,
beta-alanine-N, N'-diacetic acid, aspartic acid-N, N'-diacetic acid and aspartic acid-N-monoacetic acid (described in EP-A-509382) ,
chelating agents based on iminodisuccinic acid (IDSA) (as described in EP-A-509382) ,
ethanoldiglycine acid, and
tetrasodium glutamate diacetate (GLDA) such as Dissolvine GL38 or 45S from Akzo Nobel.
Among the chelating agents mentioned, ethylenediamine-tetraacetic acid (EDTA) , diethylenetriaminepentaacetic acid (DTPA) , S, S'-ethylenediaminedisuccinic acid (EDDS) , trisodium ethylenediamine disuccinate, ethylenediaminetetramethylenephosphonic acid (EDTMP) , and tetrasodium glutamate diacetate (GLDA) , and a combination thereof, are preferably used.
With the presence of the chelating agent, the composition according to the present invention is stable. It can remain stable for at least two months at various temperatures for example, 4℃, at room temperature (25℃) , 37℃, 45℃ and 55℃.
Advantageously, the chelating agent is present in an amount ranging from 0.05 wt. %to 5 wt. %, preferably from 0.1 wt. %to 1 wt. %, and more preferably from 0.15 wt. %to 0.6 wt. %, relative to the total weight of the composition.
Phenolic antioxidants
According to the first aspect, the composition according to the present invention comprises at least one phenolic antioxidant.
As phenolic antioxidants, mention may be made of, those which have a hindered phenol structure or a semi-hindered phenol structure within the molecule. As specific examples of such compounds, mention may be made of, 3, 5-bis (1, 1-dimethylethyl) -4-hydroxybenzenepropanoic acid) which has INCI name of pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, 2, 6-di-tert-butyl-4-methylphenol, 2, 6-di-tert-butyl-4-ethylphenol, mono-or di-or tri- (α-methylbenzyl) phenol, 2, 2’ -methylenebis (4-ethyl-6-tert-butylphenol) , 2, 2’ -methylenebis (4-methyl-6-tert-butylphenol) , 4, 4’ -butylidenebis (3-methyl-6-tert-butylphenol) , 4, 4’ -thiobis (3-methyl-6-tert-butylphenol) , 2, 5-di-tert-butylhydroquinone, 2, 5-di-tert-amylhydroquinone, tris [N- (3, 5-di-tert-butyl-4-hydroxybenzyl) ] isocyanurate, 1, 1, 3-tris (2-methyl-4-hydroxy-5-tert-butylphenyl) butane, butylidene-1, 1bis [3- (3-tert-butyl-4-hydroxy-5-methylphenyl) propionate] , octadecyl 3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate, tetrakis [methylene-3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionato] methane, triethylene glycol bis [3- (3-tert-butyl-4-hydroxy-5-methylphenyl) propionate] , 3, 9-bis {2- [3- (3-tert-butyl-4-hydroxy-5-methylphenyl) propionyloxy] -1, 1-dimethylethyl} -2, 4, 8, 10-tetraoxaspiro [5.5] undecane, 1, 3, 5-trimethyl-2, 4, 6-tris (3, 5-di-tert-butyl-4-hydroxybenzyl) benzene, 2, 2-thiodiethylenebis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate] , N, N’ -hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , 1, 6-hexanediol bis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate] , 1, 3, 5-tris [ (4-tert-butyl-3-hydroxy-2, 6-xylyl) methyl] -1, 3, 5-triazine-2, 4, 6-trione, 2, 4-bis (n-octylthio) -6- (4-hydroxy-3, 5-di-tert-butylanilino) -1, 3, 5-triazine, 2-tert-butyl-6- (3’ -tert-butyl-5’ -methyl-2’ -hydroxybenzyl) -4-methylphenyl acrylate, 2- [1- (2-hydroxy-3, 5-di-tert-pentylphenyl) ethyl] -4, 6-di-tert-pentylphenyl acrylate, 4, 6-bis [ (octylthio) methyl] -o-cresol, 2, 4-di-tert-butylphenyl-3, 5-di-tert-butyl-4-hydroxybenzoate and 1, 6-hexanediolbis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate] .
Preferably, the phenolic antioxidant is selected from pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, N, N’ -hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , and a mixture thereof.
It was found that with the presence of a phenolic antioxidant, inparticular, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, the composition according to the present invention can remain the color unchanged at different temperatures from 4℃ to 45℃for long time, for example, at least 2 months.
Advantageously, the phenolic antioxidant is present in amount ranging from0.01 wt. %to 1 wt. %, preferably from 0.03 wt. %to 0.5 wt. %, more preferably from 0.05 wt. %to 0.2 wt. %, relative to the total weight of the composition.
Aqueous phase
The composition of the present invention comprises an aqueous phase.
The aqueous phase of the composition according to the present invention comprises water and optionally one or more water-miscible or at least partially water-miscible solvents, for instance C2 to C8 polyols or monoalcohols, such as ethanol and isopropanol.
The term “polyol” should be understood as meaning any organic molecule comprising at least two free hydroxyl groups. Examples of polyols that may be mentioned include glycerin, and glycols, for instance butylene glycol, propanediol, propylene glycol, dipropylene glycol, pentylene glycol, and isoprene glycol, caprylyl glycol.
Preferably, the at least one C2-C8 polyol is selected from propanediol, pentylene glycol, dipropylene glycol, glycerin, and a combination thereof.
The aqueous phase may represent in an amount ranging from 30 wt. %to 97.5 wt. %, preferably from 30 wt. %to 97 wt. %, more preferably from 60 wt. %to 97 wt. %, relative to the total weight of the composition.
Preferably, the composition according to the present invention comprises no oily phase.
Additional cosmetic active ingredients
Depend on the final purpose, the composition according to the present invention can comprises one or more additional cosmetic active ingredients.
As cosmetic active ingredients that may be used in the composition of the present invention, examples that may be mentioned include enzymes; flavonoids; antiaging agents; humetants; tensioning agents; soothing agents; and mixtures thereof.
It is easy for the skilled in the art to adjust the amount of the additional cosmetic active ingredient based on the final use of the composition according to the present invention.
Additional adjuvants or additives
The composition of the present invention may comprise one or more conventional cosmetic adjuvants or additives, for instance, fragrances, surfactants, preserving agents (for example, chlorphenesin and phenoxyethanol) and bactericides (for example, hydroxyacetophenone) , thickeners (for example, xanthan gum, Hydroxyethylcellulose) , and mixtures thereof.
The skilled in the art can select the amount of the additional adjuvants or additive so as not to adversely impact the final use of the composition according to the present invention.
According to a preferred embodiment, the present invention provides a composition for caring for keratin materials comprising in an aqueous phase, relative to the total weight of the composition:
i) from 1 wt. %to 4 wt. %of magnesium aluminium silicate;
ii) from 0.3 wt. %to 1.5 wt. %of salicylic acid;
iii) at least one pH adjusting agent;
iv) from 0.15 wt. %to 0.6 wt. %of at least one chelating agent; and
v) from 0.05 wt%to 0.2 wt. %of a phenolic antioxidant selected from pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, N, N’ -hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , and a mixture thereof.
The composition according to the present invention can be impregnated into a water insoluble mask tissue to form a mask.
According to the second aspect, the present invention relates to a mask for caring for keratin materials, comprising:
A) a water insoluble mask tissue, and
B) the composition according to the present invention impregnated into the mask tissue.
Water insoluble mask tissue
According to the second aspect, the mask according to the present invention comprises a water insoluble mask tissue.
For the purpose of the invention, the term “water insoluble” means that the mask tissue is not dissolvable in water and it doesn’ t break apart upon immersion in water.
The skilled in the art can choose a suitable mask tissue and the weight ratio of the mask tissue used and the composition according to the present invention based on the nature of the composition.
The mask tissue can be a woven or non-woven fabric made of natural fibers such as cotton, pulp, bamboo and cellulose fibers, semi-natural fibers such as viscose rayon fibers and synthetic fibers such as polyester fibers, polyethylene terephthalate fibers, polyethylene fibers, and polypropylene fibers. Two or more selected from the above fibers may be used in combination.
In some embodiments, the mask tissue is an alginate tissue.
Alginate tissues are known in the art and are described in WO2020001069A1.
For example, an alginate tissue may comprise a water insoluble alginate chosen from calcium alginate, strontium alginate, zinc alginate, copper alginate, manganese alginate, or a mixture thereof, preferably calcium alginate, preferably in an amount ranging from 20 wt. %to 100 wt. %, preferably from 20 wt. %to 50 wt. %, relative to the total weight of the tissue.
Preferably, when the mask tissue is an alginate tissue, the composition according to the present invention comprises a pH adjusting agent selected from sodium acetate, sodium citrate, sodium tartrate, and a combination thereof in an amount ranging from 0.01 wt. %to 1.0 wt. %, preferably from 0.05 wt. %to 0.45 wt. %, more preferably from 0.15 wt. %to 0.3 wt. %, relative to the total weight of the composition according to the present invention.
The mask tissue may be consisted of one or more layers. If a multilayer tissue is used, the material of each layer may be the same or different from each other. The multilayer tissue can be prepared by laminating multiple layers made from the materials mentioned above.
The mask tissue can have a wide variety of shapes, depending on the desired use and characteristic of the mask.
The mask tissue is typically designed to fit the area of the skin to which topical application is desired. For example, when the mask is applied to the face, the mask tissue is designed to correspond to the shape of the face avoiding the eye, nostril, and mouth areas, as necessary.
Preferably, the weight ratio of the water insoluble substrate and the composition ranges from 1: 3 to 1: 20. More preferably, the weight ratio of the water insoluble substrate and the composition ranges from 1: 10 to 1: 18.
Use
The mask according to the present invention can be used as a skin mask and is intended for topical application and for skin care.
According to the third aspect, the present invention provides a non-therapeutic process for caring for keratin materials, comprising the steps of:
(i) applying the composition or the mask according to the present invention on the keratin materials;
(ii) allowing the composition or the mask to remain on the keratin materials for a period of time; and
(iii) removing the composition or the mask from the keratin materials.
By “used as a skin mask” it may be understood that the composition or the mask as defined above are applied on at least one zone of the skin.
In particular, the composition or the mask as defined above are applied on facial skin and/or eye skin.
Preferably, the application time is from 5 minutes to 45 minutes, preferably from 10 minutes to 30 minutes.
The following examples serve to illustrate the present invention without, however, being limiting in nature.
EXAMPLES
Main raw materials used in examples, trade names and supplier thereof are listed in Table 1.
Table 1
Tissue used: made of 100%copper ammonia fibre, with a thickness of 0.3mm, available under the tradename SE384 from the company Asahi-Kasei.
Comparative Examples 1-3 and Invention Examples 1-3
Compositions of comparative examples (CE. ) 1-3 and invention examples (IE. ) 1-3 were prepared according to the amounts given in Table 2. The amount of each component is given in%by weight of the total weight of the composition.
Table 2
Preparation process:
The compositions listed above were prepared by mixing all ingredients and stirring them to obtain a homogenous mixture.
Masks were prepared by impregnating a tissue with the above compositions, respectively, wherein the weight ratio of the substrate used and the composition is 1: 17.
Evaluation:
The stability of compositions obtained above were evaluated in terms of viscosity, pH, and appearance at 4℃, room temperature (25℃) , 37℃, 45℃, and 55℃ as follows.
Viscosity
The viscosity of a composition was measured at 25℃ upon preparation, and after being remained at 25℃ or 45℃ for a certain period of time, using a Rheomat 100 Plus viscometer equipped with a spindle M2, the measurement being performed after 10 minutes of rotation of the spindle in a composition (after which time stabilization of the viscosity and of the spin speed of the spindle are observed) , at a shear rate of 200 rpm.
pH value
The pH value of a composition was measured at 25℃ upon preparation, and after being remained at 25℃ or 45℃ for a certain period of time.
Appearance
The samples’ appearance was observed when its temperature achieved the indicated temperature (T0) , 1 month after its temperature achieved the indicated temperature (T1M) , and 2 months after its temperature achieved the indicated temperature (T2M) .
The appearance will be evaluated as conform if its appearance does not change as compared with its appearance at T0.
The results in terms of appearance, pH, and viscosity of the compositions according to comparative examples and inventive examples were listed in Table 3.
Table 3
It can be also seen from Table 3 that the appearance, viscosity, and pH values of compositions according to the present invention did not change substantially after being remained at 4℃, 25℃, 37℃, 45℃, and/or 55℃ for a certain period of time, thus composition according to the present invention are stable.
Claims (16)
- A composition comprising in an aqueous phase:i) magnesium aluminium silicate;ii) at least one hydroxyl acid;iii) at least one pH adjusting agent;iv) at least one chelating agent; andv) at least one phenolic antioxidant.
- Composition of claim 1, wherein magnesium aluminum silicate is present in an amount ranging from 0.1 wt. %to 10 wt. %, preferably from 0.5 wt. %to 6 wt. %, more preferably from 1 wt. %to 4 wt. %, relative to the total weight of the composition.
- Composition of claim 1 or 2, wherein the hydroxy acid is selected from alpha hydroxy acid and beta hydroxy acid, and combinations thereof.
- Composition of claim 3, wherein the alpha hydroxy acid is selected from lactic acid, glycolic acid, tartaric acid, mandelic acid, citric acid, and combinations thereof.
- Composition of claim 3, wherein the beta hydroxy acid is selected from salicylic acid and its derivatives of formula (I) :
wherein R is a linear, branched or cyclic saturated aliphatic group or an aliphatic unsaturated group containing one or a number of double bonds, which may or may not be conjugated, these groups containing from 2 to 22, preferably 3 to 11 carbon atoms and being able to be substituted for example by at least one substituent selected from (a) halogen atoms, (b) the trifluoromethyl group, (c) hydroxyl groups in the free form or esterified by an acid having from 1 to 6 carbon atoms or (d) a carboxyl functional group which is free or esterified by a lower alcohol having from 1 to 6 carbon atoms;R' is a hydroxyl group or an ester functional group of formula (II) :
wherein R 1 is a linear or branched saturated or unsaturated aliphatic group having from 1 to 18 carbon atoms - Composition of any of claims 1 to 5, wherein hydroxy acid is present in an amount ranging from 0.1 wt. %to 3wt. %, preferably from 0.2 wt. %to 2 wt. %, and more preferably from 0.3 wt. %to 1.5wt. %, relative to the total weight of the composition.
- Composition of any of claims 1 to 6, wherein the pH adjusting agent is selected from triethanolamine (TEA) , amine base tromethamine, tetrahydroxypropyl ethylenediamine, diethanolamine, aminomethyl propanol, sodium hydroxide, potassium hydroxide, ammonium hydroxide, sodium phosphate, sodium gluconate, sodium lactate, sodium citrate, sodium acetate potassium citrate, sodium bicarbonate, potassium bicarbonate, sodium dihydrogen phosphate, potassium dihydrogen phosphate, sodium carbonate, sodium hydrogen carbonate, magnesium carbonate, calcium carbonate, and a combination thereof, preferably the pH adjusting agent is selected from triethanolamine (TEA) , amine base tromethamine, tetrahydroxypropyl ethylenediamine, diethanolamine, aminomethyl propanol, and a combination thereof, more preferably, the pH adjusting agent is triethanolamine.
- Composition of any of claims 1 to 7, wherein the composition has a pH of 4-8, preferably 5-8, more preferably 5-6.
- Composition according to any of claims 1 to 8, wherein the chelating agent is selected from diethylenetriaminepentaacetic acid (DTPA) , ethylenediaminedisuccinic acid (EDDS) , trisodium ethylenediamine disuccinate, ethylenediaminetetraacetic acid (EDTA) , ethylenediamine-N, N'-diglutaric acid (EDDG) , glycinamide-N, N'-disuccinic acid (GADS) , 2-hydroxypropylenediamine-N, N'-disuccinic acid (HPDDS) , ethylenediamine-N, N'-bis (ortho-hydroxyphenylacetic acid) (EDDHA) , N, N'-bis (2-hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) , nitrilotriacetic acid (NTA) , methylglycine diacetic acid (MGDA) , N-2-hydroxyethyl-N, N-diacetic acid, glyceryl imino diacetic acid, iminodiacetic acid-N-2-hydroxypropyl sulfonic acid, aspartic acid N-carboxymethyl N-2-hydroxypropyl-3-sulfonic acid, beta-alanine-N, N'-diacetic acid, aspartic acid-N, N'-diacetic acid, aspartic acid-N-onoacetic acid, chelating agents based on iminodisuccinic acid (IDSA) , ethanoldiglycine acid, and tetrasodium glutamate diacetate (GLDA) , preferably, the chelating agent is selected from ethylenediamine-tetraacetic acid (EDTA) , diethylenetriaminepentaacetic acid (DTPA) , S, S'-ethylenediaminedisuccinic acid (EDDS) , trisodium ethylenediamine disuccinate, ethylenediaminetetramethylenephosphonic acid (EDTMP) , and tetrasodium glutamate diacetate (GLDA) , and a combination thereof.
- The composition according to any one of claims 1 to 9, wherein the chelating agent is present in an amount ranging from 0.05 wt. %to 5 wt. %, preferably from 0.1 wt. %to 1 wt. %, and more preferably from 0.15 wt. %to 0.6 wt. %, relative to the total weight of the composition.
- Composition according to any one of claims 1 to 10, wherein the phenolic antioxidant is selected from pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, 2, 6-di-tert-butyl-4-methylphenol, 2, 6-di-tert-butyl-4-ethylphenol, mono-or di-or tri- (α-methylbenzyl) phenol, 2, 2’-methylenebis (4-ethyl-6-tert-butylphenol) , 2, 2’-methylenebis (4-methyl-6-tert-butylphenol) , 4, 4’-butylidenebis (3-methyl-6-tert-butylphenol) , 4, 4’-thiobis (3-methyl-6-tert-butylphenol) , 2, 5-di-tert-butylhydroquinone, 2, 5-di-tert-amylhydroquinone, tris [N- (3, 5-di-tert-butyl-4-hydroxybenzyl) ] isocyanurate, 1, 1, 3-tris (2-methyl-4-hydroxy-5-tert-butylphenyl) butane, butylidene-1, 1bis [3- (3-tert-butyl-4-hydroxy-5-methylphenyl) propionate] , octadecyl 3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate, tetrakis [methylene-3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionato] methane, triethylene glycol bis [3- (3-tert-butyl-4-hydroxy-5-methylphenyl) propionate] , 3, 9-bis {2- [3- (3-tert-butyl-4-hydroxy-5-methylphenyl) propionyloxy] -1, 1-dimethylethyl} -2, 4, 8, 10-tetraoxaspiro [5.5] undecane, 1, 3, 5-trimethyl-2, 4, 6-tris (3, 5-di-tert-butyl-4-hydroxybenzyl) benzene, 2, 2-thiodiethylenebis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate] , N, N’-hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , 1, 6-hexanediol bis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate] , 1, 3, 5-tris [ (4-tert-butyl-3-hydroxy-2, 6-xylyl) methyl] -1, 3, 5-triazine-2, 4, 6-trione, 2, 4-bis (n-octylthio) -6- (4-hydroxy-3, 5-di-tert-butylanilino) -1, 3, 5-triazine, 2-tert-butyl-6- (3’-tert-butyl-5’-methyl-2’-hydroxybenzyl) -4-methylphenyl acrylate, 2- [1- (2-hydroxy-3, 5-di-tert-pentylphenyl) ethyl] -4, 6-di-tert-pentylphenyl acrylate, 4, 6-bis [ (octylthio) methyl] -o-cresol, 2, 4-di-tert-butylphenyl-3, 5-di-tert-butyl-4-hydroxybenzoate and 1, 6-hexanediolbis [3- (3, 5-di-tert-butyl-4-hydroxyphenyl) propionate] .
- Composition according to any of claims 1 to 9, wherein the phenolic antioxidant is present in amount ranging from 0.01 wt. %to 1 wt. %, preferably from 0.03 wt. %to 0.5 wt. %, more preferably from 0.05 wt. %to 0.2 wt. %, relative to the total weight of the composition.
- The composition according to claim 10, comprising, relative to the total weight of the composition:i) from 1 wt. %to 4 wt. %of magnesium aluminium silicate;ii) from 0.3 wt. %to 1.5 wt. %of salicylic acid;iii) at least one pH adjusting agent;iv) from 0.15 wt. %to 0.6 wt. %of at least one chelating agent; andv) from 0.05 wt. %to 0.2 wt. %of a phenolic antioxidant selected from pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, N, N’-hexamethylenebis (3, 5-di-tert-butyl-4-hydroxyhydrocinnamide) , and a mixture thereof.
- A mask for caring for keratin materials, comprising in an aqueous phase:A) a water insoluble mask tissue, andB) the composition according to any of claims 1-13 impregnated into the mask tissue.
- The mask according to claim 14, wherein the weight ratio of the water insoluble substrate and the composition ranges from 1: 3 to 1: 20. More preferably, the weight ratio of the water insoluble substrate and the composition ranges from 1: 10 to 1: 18.
- A non-therapeutic process for caring for keratin materials, comprising the steps of:(i) applying the composition according to any of claims 1-13 or the mask according to claim 14 or 15 on the keratin materials;(ii) allowing the composition or the mask to remain on the keratin materials for a period of time; and(iii) removing the composition or the mask from the keratin materials.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2022/123076 WO2024065609A1 (en) | 2022-09-30 | 2022-09-30 | Composition for caring for keratin materials and mask containing the same |
| FR2211947A FR3140265A1 (en) | 2022-09-30 | 2022-11-17 | Care composition of keratinous materials and mask containing it |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2022/123076 WO2024065609A1 (en) | 2022-09-30 | 2022-09-30 | Composition for caring for keratin materials and mask containing the same |
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| WO2024065609A1 true WO2024065609A1 (en) | 2024-04-04 |
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| PCT/CN2022/123076 WO2024065609A1 (en) | 2022-09-30 | 2022-09-30 | Composition for caring for keratin materials and mask containing the same |
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| FR (1) | FR3140265A1 (en) |
| WO (1) | WO2024065609A1 (en) |
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| US20160074315A1 (en) * | 2007-11-19 | 2016-03-17 | Stiefel Laboratories, Inc. | Topical cosmetic skin lightening compositions and methods of use thereof |
| CN105120834A (en) * | 2013-04-22 | 2015-12-02 | 新科蒂斯公司 | Antioxidant compositions and methods of using the same |
| US20180243189A1 (en) * | 2014-03-26 | 2018-08-30 | Symrise Ag | Oil-in-Water Emulsions Containing 4-Hydroxyacetophenone and Anionic Emulsifiers |
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