WO2024019512A3 - 미생물에 의해 발현이 유도되는 dbn1 유전자 또는 그 산물을 유효성분으로 포함하는 노화 개선용 조성물 - Google Patents

미생물에 의해 발현이 유도되는 dbn1 유전자 또는 그 산물을 유효성분으로 포함하는 노화 개선용 조성물 Download PDF

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Publication number
WO2024019512A3
WO2024019512A3 PCT/KR2023/010381 KR2023010381W WO2024019512A3 WO 2024019512 A3 WO2024019512 A3 WO 2024019512A3 KR 2023010381 W KR2023010381 W KR 2023010381W WO 2024019512 A3 WO2024019512 A3 WO 2024019512A3
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aging
composition
dbn1
active ingredient
microorganism
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PCT/KR2023/010381
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English (en)
French (fr)
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WO2024019512A2 (ko
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남기택
김광휘
김지현
정유숙
허지원
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연세대학교 산학협력단
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Publication of WO2024019512A2 publication Critical patent/WO2024019512A2/ko
Publication of WO2024019512A3 publication Critical patent/WO2024019512A3/ko

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/318Foods, ingredients or supplements having a functional effect on health having an effect on skin health and hair or coat

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Birds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

본 발명은 Dbn1을 발현하는 미생물을 유효성분으로 포함하는 항노화용 조성물 및 이를 이용한 항노화용 화장료 조성물에 관한 것이다. 본 발명은 장내 미생물과 노화의 연관관계에 관한 연구로서, 노화를 개선할 수 있는 장내 미생물을 발견함으로써, 노화를 개선할 수 있는 조성물로 유용하게 이용될 수 있다.
PCT/KR2023/010381 2022-07-20 2023-07-19 미생물에 의해 발현이 유도되는 dbn1 유전자 또는 그 산물을 유효성분으로 포함하는 노화 개선용 조성물 WO2024019512A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2022-0089767 2022-07-20
KR1020220089767A KR20240012178A (ko) 2022-07-20 2022-07-20 미생물에 의해 발현이 유도되는 Dbn1 유전자 또는 그 산물을 유효성분으로 포함하는 노화 개선용 조성물

Publications (2)

Publication Number Publication Date
WO2024019512A2 WO2024019512A2 (ko) 2024-01-25
WO2024019512A3 true WO2024019512A3 (ko) 2024-03-07

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PCT/KR2023/010381 WO2024019512A2 (ko) 2022-07-20 2023-07-19 미생물에 의해 발현이 유도되는 dbn1 유전자 또는 그 산물을 유효성분으로 포함하는 노화 개선용 조성물

Country Status (2)

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KR (1) KR20240012178A (ko)
WO (1) WO2024019512A2 (ko)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200037731A (ko) * 2018-10-01 2020-04-09 한국생명공학연구원 아커만시아 뮤시니필라 균주 또는 이의 배양물을 유효성분으로 함유하는 노화방지용 조성물

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200037731A (ko) * 2018-10-01 2020-04-09 한국생명공학연구원 아커만시아 뮤시니필라 균주 또는 이의 배양물을 유효성분으로 함유하는 노화방지용 조성물

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
(ETNEWS article. [KISTI Science Scent] Youth Is Made of Poop, Not Age?). Retrieved from the Internet URL : https://www.ctncws.com/20230317000118 (20 March 2023). See entire document. *
KWANG H. KIM ET AL: "Gut microbiota of the young ameliorates physical fitness of the aged in mice", MICROBIOME, BIOMED CENTRAL LTD, LONDON, UK, vol. 10, no. 1, 26 December 2022 (2022-12-26), London, UK, pages 1 - 15, XP021312509, DOI: 10.1186/s40168-022-01386-w *
LIU YAN ET AL: "Effective expression of drebrin in hippocampus improves cognitive function and alleviates lesions of alzheimer's disease in APP (swe)/PS1 (AE9) mice", CNS NEUROSCIENCE & THERAPEUTICS, WILEY-BLACKWELL PUBLISHING LTD., GB, vol. 23, no. 7, 1 July 2017 (2017-07-01), GB , pages 590 - 604, XP093087024, ISSN: 1755-5930, DOI: 10.1111/cns.12706 *
LUTFI H. ALFARSI: "Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer", CANCERS, MDPI AG, CH, vol. 12, no. 1549, CH , pages 1 - 12, XP093161500, ISSN: 2072-6694, DOI: 10.3390/cancers12061549 *
W. MOHAMMEDSAEED ET AL: "Lactobacillus rhamnosus GG Inhibits the Toxic Effects of Staphylococcus aureus on Epidermal Keratinocytes", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 80, no. 18, 15 September 2014 (2014-09-15), US , pages 5773 - 5781, XP055347831, ISSN: 0099-2240, DOI: 10.1128/AEM.00861-14 *
WALAA MOHAMMEDSAEED: "Characterisation of the potential of probiotics or their extracts as therapy for skin", A THESIS SUBMITTED TO THE UNIVERSITY OF MANCHESTER FOR THE DEGREE OF DOCTOR OF PHILOSOPHY IN THE FACULTY OF MEDICAL AND HUMAN SCIENCES, 1 January 2014 (2014-01-01), pages 1 - 356, XP093161479 *

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WO2024019512A2 (ko) 2024-01-25
KR20240012178A (ko) 2024-01-29

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